Strain Name:
C57BL/6J-MtgxR5215Btlr/Mmmh
Stock Number:
042788-MU
Citation ID:
RRID:MMRRC_042788-MU
Other Names:
R5215 (G1), C57BL/6J-MtgxR5215Btlr
Major Collection:

Gene Information

Atic
Name: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Synonyms: 2610509C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108147
HGNC: HGNC:794
Homologene: 2983
Jmjd1c
Name: jumonji domain containing 1C
Synonyms: TRIP8, 5430433L24Rik, D630035I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 108829
Homologene: 3129
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNA-PKcs, slip, DNAPDcs, DNA-PK, XRCC7, DOXNPH, dxnph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Tnpo3
Name: transportin 3
Synonyms: 5730544L10Rik, C430013M08Rik, D6Ertd313e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 320938
Homologene: 40848
Herc4
Name: hect domain and RLD 4
Synonyms: 4921531D01Rik, 1700056O17Rik, 9530080M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67345
VEGA: 10
Homologene: 56715
Mtor
Name: mechanistic target of rapamycin kinase
Synonyms: FKBP-rapamycin-associated protein FRAP, 2610315D21Rik, RAPT1, RAFT1, flat, Frap1, mechanistic target of rapamycin (serine/threonine kinase)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56717
HGNC: HGNC:3942
Homologene: 3637
Pard3
Name: par-3 family cell polarity regulator
Synonyms: ASIP, D8Ertd580e, PAR-3, Par3, Pard3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 93742
Homologene: 10489
Mast4
Name: microtubule associated serine/threonine kinase family member 4
Synonyms: 4930420O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 328329
Homologene: 42094
Drosha
Name: drosha, ribonuclease type III
Synonyms: 1110013A17Rik, Etohi2, Rnasen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14000
Homologene: 8293
Ubr1
Name: ubiquitin protein ligase E3 component n-recognin 1
Synonyms: E3 alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22222
Homologene: 7582
Tars2
Name: threonyl-tRNA synthetase 2, mitochondrial (putative)
Synonyms: 2610024N01Rik, Tarsl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71807
Homologene: 23520
Tnip1
Name: TNFAIP3 interacting protein 1
Synonyms: A20-binding inhibitor of NF-kappa B activation, ABIN1, VAN, Nef
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 57783
Homologene: 31355
Zwilch
Name: zwilch kinetochore protein
Synonyms: 2310031L18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68014
Homologene: 32381
Eftud2
Name: elongation factor Tu GTP binding domain containing 2
Synonyms: U5-116kD, 116kDa, Snrp116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20624
Homologene: 3133
Mdn1
Name: midasin AAA ATPase 1
Synonyms: LOC213784, 4833432B22Rik, D4Abb1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100019
Homologene: 39689
Prpf8
Name: pre-mRNA processing factor 8
Synonyms: DBF3/PRP8, Prp8, D11Bwg0410e, Sfprp8l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192159
Homologene: 4706
Son
Name: Son DNA binding protein
Synonyms: 2900011L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20658
Homologene: 10551
Cdc45
Name: cell division cycle 45
Synonyms: Cdc45l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12544
HGNC: HGNC:1739
Homologene: 2616
Iars2
Name: isoleucine-tRNA synthetase 2, mitochondrial
Synonyms: 2010002H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 381314
Homologene: 7118
Pan3
Name: PAN3 poly(A) specific ribonuclease subunit
Synonyms: 2700050F09Rik, A430027N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 72587
Homologene: 6372
Hnrnpk
Name: heterogeneous nuclear ribonucleoprotein K
Synonyms: hnRNPK, Hnrpk, KBBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 15387
HGNC: HGNC:5044
Homologene: 81909
Dnaaf5
Name: dynein, axonemal assembly factor 5
Synonyms: Heatr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 433956
Homologene: 41198
Slf2
Name: SMC5-SMC6 complex localization factor 2
Synonyms: 6030443O07Rik, Fam178a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226151
VEGA: 19
Homologene: 23077
Gigyf2
Name: GRB10 interacting GYF protein 2
Synonyms: A830080H02Rik, 2610016F01Rik, Tnrc15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227331
Homologene: 41048
Dpep2
Name: dipeptidase 2
Synonyms: MBD-2, F630103D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 319446
Homologene: 49703
Cd164l2
Name: CD164 sialomucin-like 2
Synonyms: 2310047N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69655
Homologene: 19231
Alas1
Name: aminolevulinic acid synthase 1
Synonyms: 5-aminolevulinate synthase, succinyl-CoA: glycine C-succinyl transferase, Alas-1, ALAS-N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 11655
HGNC: HGNC:396
Homologene: 55478
Chd6
Name: chromodomain helicase DNA binding protein 6
Synonyms: 6330406J24Rik, 5430439G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71389
Homologene: 32772
Gorasp2
Name: golgi reassembly stacking protein 2
Synonyms: GRASP55, 5730520M13Rik, 9430094F20Rik, GOLPH2, GRS2, p59, ENSMUSG00000075299
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70231
Homologene: 9180
Rprd1a
Name: regulation of nuclear pre-mRNA domain containing 1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225283
VEGA: 18
Homologene: 124432
Taf6l
Name: TATA-box binding protein associated factor 6 like
Synonyms: PAF65A, C530024J06Rik, 2810417N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225895
Homologene: 4728
Tbc1d2
Name: TBC1 domain family, member 2
Synonyms: LOC381605, PARIS-1, PARIS1, A630005A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381605
Homologene: 10190
Grin1
Name: glutamate receptor, ionotropic, NMDA1 (zeta 1)
Synonyms: NMDAR1, NR1, Nmdar, M100174, GluRzeta1, Rgsc174
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14810
HGNC: HGNC:4584
Homologene: 7187
Atp6v1c2
Name: ATPase, H+ transporting, lysosomal V1 subunit C2
Synonyms: 1110038G14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68775
Homologene: 15866
Dhodh
Name: dihydroorotate dehydrogenase
Synonyms: 2810417D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56749
HGNC: HGNC:2867
Homologene: 1043
Oca2
Name: oculocutaneous albinism II
Synonyms: D7H15S12, D7H15S12, p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18431
HGNC: HGNC:8101
Homologene: 37281
Ano4
Name: anoctamin 4
Synonyms: A330096O15Rik, Tmem16d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 320091
Homologene: 66599
Zc3h12a
Name: zinc finger CCCH type containing 12A
Synonyms: Mcpip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230738
Homologene: 11824
Dnah11
Name: dynein, axonemal, heavy chain 11
Synonyms: lrd, b2b1203Clo, b2b1279Clo, b2b598Clo, b2b1289Clo, b2b1727Clo, Dnahc11, avc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13411
HGNC: HGNC:2942
Homologene: 2801
Mx1
Name: MX dynamin-like GTPase 1
Synonyms: myxovirus (influenza) resistance 1 polypeptide, Mx-1, Mx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17857
Lama3
Name: laminin, alpha 3
Synonyms: nicein, 150kDa, [a]3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Hrc
Name: histidine rich calcium binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15464
HGNC: HGNC:5178
Homologene: 137234
Gzmn
Name: granzyme N
Synonyms: GrN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 245839
VEGA: 14
Homologene: 87221
Mink1
Name: misshapen-like kinase 1 (zebrafish)
Synonyms: Misshapen/NIKs-related kinase, MINK, Ysk2, Map4k6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 50932
Homologene: 56762
Cfap69
Name: cilia and flagella associated protein 69
Synonyms: A330021E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 207686
Homologene: 11718
Olfr1285
Name: olfactory receptor 1285
Synonyms: GA_x6K02T2Q125-72459956-72460837, MOR248-17P, MOR248-25_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 545447
Ptprt
Name: protein tyrosine phosphatase, receptor type, T
Synonyms: RPTPrho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19281
HGNC: HGNC:9682
Homologene: 56924
Aldoart2
Name: aldolase 1 A, retrogene 2
Synonyms: Aldo1-ps1, 4933425L11Rik, Aldoa-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 79459
Homologene: 134148
Olfr952
Name: olfactory receptor 952
Synonyms: GA_x6K02T2PVTD-33124064-33123120, MOR171-21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235248
VEGA: 9
Homologene: 133698
Glmn
Name: glomulin, FKBP associated protein
Synonyms: Fap68, Fap48, 9330160J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 170823
Homologene: 14239
Elfn2
Name: leucine rich repeat and fibronectin type III, extracellular 2
Synonyms: Lrrc62
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 207393
VEGA: 15
Homologene: 18835
Rp1l1
Name: retinitis pigmentosa 1 homolog like 1
Synonyms: Dcdc4, Rp1hl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 271209
VEGA: 14
Homologene: 105870
Kcng1
Name: potassium voltage-gated channel, subfamily G, member 1
Synonyms: OTTMUSG00000016048
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241794
HGNC: HGNC:6248
Homologene: 20515
Cps1
Name: carbamoyl-phosphate synthetase 1
Synonyms: CPS, CPSase I, 4732433M03Rik, D1Ucla3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227231
HGNC: HGNC:2323
Homologene: 68208
Vmn2r9
Name: vomeronasal 2, receptor 9
Synonyms: EG435864
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 435864
Homologene: 129606
Rbm42
Name: RNA binding motif protein 42
Synonyms: 1700003D06Rik, 3100004P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68035
Homologene: 32579
Cdc42ep2
Name: CDC42 effector protein (Rho GTPase binding) 2
Synonyms: Borg1, Cep2, 1110008C05Rik, D19Bwg1013e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 104252
VEGA: 19
Homologene: 4933
Prag1
Name: PEAK1 related kinase activating pseudokinase 1
Synonyms: NACK, D8Ertd82e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244418
Homologene: 18256
Slc22a16
Name: solute carrier family 22 (organic cation transporter), member 16
Synonyms: FLIPT2, OKB1, OCT6, CT2, 4921504E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70840
Homologene: 41957
Pgghg
Name: protein glucosylgalactosylhydroxylysine glucosidase
Synonyms: 5730511L01Rik, Athl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212974
Homologene: 16023
Decr1
Name: 2,4-dienoyl CoA reductase 1, mitochondrial
Synonyms: Decr, Nadph, 1200012F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67460
HGNC: HGNC:2753
Homologene: 68178
Saxo1
Name: stabilizer of axonemal microtubules 1
Synonyms: 4930500O09Rik, Fam154a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75811
Homologene: 27548
Olfr521
Name: olfactory receptor 521
Synonyms: GA_x6K02T2PBJ9-2443810-2444775, MOR101-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258353
Homologene: 128108
Gabra1
Name: gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
Synonyms: GABAA alpha 1, Gabra-1, GABAAR alpha1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14394
HGNC: HGNC:4075
Homologene: 629
Olfr682-ps1
Name: olfactory receptor 682, pseudogene 1
Synonyms: GA_x6K02SYW8DF-188-1037, GA_x6K02T2PBJ9-7755919-7755070, MOR40-6P, MOR40-19_p, Olfr217-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258187
Pdcd2l
Name: programmed cell death 2-like
Synonyms: 6030457N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68079
Homologene: 41861
Txndc16
Name: thioredoxin domain containing 16
Synonyms: 5730420B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 70561
Homologene: 18197
Gm340
Name: predicted gene 340
Synonyms: LOC381224
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Olfr103
Name: olfactory receptor 103
Synonyms: MOR250-3, GA_x6K02T2PSCP-1798423-1797482, MOR250-8_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258830
Homologene: 115555
Gimap8
Name: GTPase, IMAP family member 8
Synonyms: LOC243374, IAN9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243374
Homologene: 69703
Crb2
Name: crumbs family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241324
Homologene: 45474
Pigu
Name: phosphatidylinositol glycan anchor biosynthesis, class U
Synonyms: 5430426F17Rik, Cdc91l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228812
Homologene: 6553
Slc11a1
Name: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Synonyms: host resistance locus Bcg/Ity/Lsh, Nramp, Bcg, Lsh, Ity, ity, Nramp1, Ity1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18173
Homologene: 73884
Gm10032
Name: predicted gene 10032
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Klra14-ps
Name: killer cell lectin-like receptor subfamily A, member 14, pseudogene
Synonyms: Ly49N, EG654449, Gm15858, Klra14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 654449
Cdk5
Name: cyclin-dependent kinase 5
Synonyms: Crk6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12568
HGNC: HGNC:1774
Homologene: 3623
Pkmyt1
Name: protein kinase, membrane associated tyrosine/threonine 1
Synonyms: Myt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268930
VEGA: 17
Homologene: 31227
Krtap5-3
Name: keratin associated protein 5-3
Synonyms: A030007E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 77215
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 67,166,380 bp
  • T to C, chromosome 1 at 71,564,507 bp
  • A to T, chromosome 1 at 74,383,777 bp
  • C to A, chromosome 1 at 87,365,266 bp
  • T to C, chromosome 1 at 185,294,769 bp
  • A to T, chromosome 2 at 25,303,907 bp
  • A to G, chromosome 2 at 37,793,753 bp
  • G to A, chromosome 2 at 70,689,254 bp
  • T to C, chromosome 2 at 111,409,286 bp
  • T to C, chromosome 2 at 120,904,044 bp
  • C to A, chromosome 2 at 155,335,329 bp
  • C to T, chromosome 2 at 160,949,953 bp
  • C to T, chromosome 2 at 162,278,164 bp
  • C to T, chromosome 2 at 168,263,133 bp
  • A to G, chromosome 3 at 95,746,640 bp
  • T to C, chromosome 4 at 15,929,795 bp
  • T to C, chromosome 4 at 32,741,418 bp
  • C to A, chromosome 4 at 46,614,006 bp
  • A to T, chromosome 4 at 86,445,816 bp
  • A to G, chromosome 4 at 125,126,913 bp
  • C to A, chromosome 4 at 133,221,478 bp
  • A to T, chromosome 4 at 148,453,983 bp
  • G to T, chromosome 5 at 5,589,133 bp
  • T to A, chromosome 5 at 24,419,461 bp
  • A to G, chromosome 5 at 107,561,886 bp
  • A to G, chromosome 5 at 108,846,485 bp
  • G to A, chromosome 5 at 139,161,877 bp
  • A to G, chromosome 5 at 147,455,105 bp
  • C to T, chromosome 6 at 29,582,153 bp
  • A to T, chromosome 6 at 48,651,083 bp
  • C to A, chromosome 6 at 130,157,683 bp
  • A to T, chromosome 7 at 30,645,962 bp
  • A to T, chromosome 7 at 34,192,889 bp
  • A to T, chromosome 7 at 45,336,091 bp
  • A to T, chromosome 7 at 56,295,498 bp
  • A to G, chromosome 7 at 99,767,510 bp
  • G to A, chromosome 7 at 105,126,564 bp
  • T to C, chromosome 7 at 140,946,564 bp
  • T to A, chromosome 7 at 142,202,237 bp
  • G to A, chromosome 8 at 36,099,889 bp
  • C to A, chromosome 8 at 105,989,343 bp
  • G to A, chromosome 8 at 109,606,343 bp
  • G to A, chromosome 8 at 127,378,264 bp
  • A to T, chromosome 9 at 39,426,623 bp
  • T to G, chromosome 9 at 64,146,874 bp
  • C to A, chromosome 9 at 106,243,375 bp
  • T to A, chromosome 10 at 40,581,390 bp
  • T to A, chromosome 10 at 63,289,097 bp
  • T to A, chromosome 10 at 67,240,701 bp
  • T to C, chromosome 10 at 89,317,303 bp
  • T to C, chromosome 11 at 42,154,828 bp
  • T to C, chromosome 11 at 54,940,769 bp
  • T to C, chromosome 11 at 70,608,655 bp
  • G to A, chromosome 11 at 75,500,204 bp
  • C to T, chromosome 11 at 102,871,120 bp
  • T to C, chromosome 12 at 17,291,658 bp
  • G to A, chromosome 12 at 55,565,419 bp
  • T to C, chromosome 12 at 118,157,361 bp
  • A to G, chromosome 13 at 58,395,252 bp
  • A to T, chromosome 13 at 103,334,085 bp
  • A to T, chromosome 14 at 45,211,140 bp
  • A to G, chromosome 14 at 56,167,862 bp
  • C to T, chromosome 14 at 64,030,013 bp
  • T to C, chromosome 14 at 66,792,549 bp
  • T to C, chromosome 15 at 12,885,133 bp
  • T to A, chromosome 15 at 78,674,201 bp
  • C to A, chromosome 16 at 15,772,121 bp
  • C to T, chromosome 16 at 18,795,897 bp
  • T to A, chromosome 16 at 91,656,675 bp
  • T to C, chromosome 16 at 97,448,360 bp
  • G to A, chromosome 17 at 23,732,592 bp
  • T to A, chromosome 17 at 37,336,813 bp
  • A to G, chromosome 18 at 12,577,900 bp
  • G to T, chromosome 18 at 24,488,200 bp
  • T to C, chromosome 19 at 5,918,210 bp
  • T to C, chromosome 19 at 8,778,053 bp
  • T to C, chromosome 19 at 41,585,932 bp
  • T to G, chromosome 19 at 44,948,037 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5215 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042788-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.