Strain Name:
C57BL/6J-MtgxR5337Btlr/Mmmh
Stock Number:
042917-MU
Citation ID:
RRID:MMRRC_042917-MU
Other Names:
R5337 (G1), C57BL/6J-MtgxR5337Btlr
Major Collection:

Gene Information

Pds5b
Name: PDS5 cohesin associated factor B
Synonyms: AS3, Aprin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100710
Homologene: 41001
Map3k4
Name: mitogen-activated protein kinase kinase kinase 4
Synonyms: MTK1, MAPKKK4, D17Rp17, RP17, D17Rp17e, Mekk4, T-associated sex reversal, Tas
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 26407
VEGA: 17
HGNC: HGNC:6856
Homologene: 31346
Dock6
Name: dedicator of cytokinesis 6
Synonyms: 2410095B20Rik, 4931431C02Rik, C330023D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319899
VEGA: 9
Homologene: 83291
Tut7
Name: terminal uridylyl transferase 7
Synonyms: 6030448M23Rik, Zcchc6, Tent3b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 214290
VEGA: 13
Homologene: 51941
Api5
Name: apoptosis inhibitor 5
Synonyms: AAC-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11800
HGNC: HGNC:594
Homologene: 4809
Phkb
Name: phosphorylase kinase beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102093
HGNC: HGNC:8927
Homologene: 247
Akap8l
Name: A kinase (PRKA) anchor protein 8-like
Synonyms: Nakap95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 54194
VEGA: 17
Homologene: 8658
Cftr
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12638
HGNC: HGNC:1884
Homologene: 55465
Zc3h18
Name: zinc finger CCCH-type containing 18
Synonyms: 1190001B23Rik, 5830416A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 76014
Homologene: 44894
Cuzd1
Name: CUB and zona pellucida-like domains 1
Synonyms: UTCZP, Itmap1, UO-44, ERG-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16433
Homologene: 7389
Mtpn
Name: myotrophin
Synonyms: V1, Gcdp, 5033418D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14489
Homologene: 40607
Chd1l
Name: chromodomain helicase DNA binding protein 1-like
Synonyms: Snf2p, 4432404A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68058
HGNC: HGNC:1916
Homologene: 11590
Zswim4
Name: zinc finger SWIM-type containing 4
Synonyms: E130119J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212168
Homologene: 18183
Gpr155
Name: G protein-coupled receptor 155
Synonyms: DEPDC3, PGR22, 1110017O10Rik, F730029F15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68526
Homologene: 16584
Slfn4
Name: schlafen 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20558
Homologene: 133236
Cspg4b
Name: chondroitin sulfate proteoglycan 4B
Synonyms: BC067074
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 408066
Cmya5
Name: cardiomyopathy associated 5
Synonyms: Myospryn, 2310076E16Rik, 2310076E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
2610507B11Rik
Name: RIKEN cDNA 2610507B11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 72503
Homologene: 34730
Fat4
Name: FAT atypical cadherin 4
Synonyms: 6030410K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 329628
Homologene: 14377
Uspl1
Name: ubiquitin specific peptidase like 1
Synonyms: E430026A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231915
Homologene: 4235
Itgb4
Name: integrin beta 4
Synonyms: CD104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192897
HGNC: HGNC:6158
Homologene: 179
Trpc3
Name: transient receptor potential cation channel, subfamily C, member 3
Synonyms: Trp3, Trrp3, Trcp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 22065
Homologene: 20708
Pilra
Name: paired immunoglobin-like type 2 receptor alpha
Synonyms: FDF03
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231805
Homologene: 8387
Rhpn1
Name: rhophilin, Rho GTPase binding protein 1
Synonyms: Rhophilin, Grbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 14787
Homologene: 7346
Tmem127
Name: transmembrane protein 127
Synonyms: 2310003P10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69470
Homologene: 9877
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50720
Grik1
Name: glutamate receptor, ionotropic, kainate 1
Synonyms: Glur-5, Glur5, D16Ium24, A830007B11Rik, D16Ium24e, Glurbeta1, GluK5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 14805
HGNC: HGNC:4579
Homologene: 68992
Greb1l
Name: growth regulation by estrogen in breast cancer-like
Synonyms: mKIAA4095, AK220484
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 381157
Homologene: 73393
Psg23
Name: pregnancy-specific glycoprotein 23
Synonyms: 1620401C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56868
Homologene: 110989
Rims4
Name: regulating synaptic membrane exocytosis 4
Synonyms: Rim4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241770
Homologene: 18123
Sntb1
Name: syntrophin, basic 1
Synonyms: beta1-Syntrophin, 59-1 DAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20649
Homologene: 9618
Neto1
Name: neuropilin (NRP) and tolloid (TLL)-like 1
Synonyms: C130005O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 246317
VEGA: 18
Homologene: 16367
Trim50
Name: tripartite motif-containing 50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 215061
Homologene: 14548
Kcnip1
Name: Kv channel-interacting protein 1
Synonyms: 2900046L02Rik, KCHIP1, 3202002F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70357
Homologene: 22824
Kif21b
Name: kinesin family member 21B
Synonyms: N-5 kinesin, 2610511N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16565
Homologene: 56868
Proz
Name: protein Z, vitamin K-dependent plasma glycoprotein
Synonyms: 1300015B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 66901
HGNC: HGNC:9460
Homologene: 2890
Gad1-ps
Name: glutamate decarboxylase 1, pseudogene
Synonyms: Gad-1ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 382407
VEGA: 10
Olfr1333
Name: olfactory receptor 1333
Synonyms: GA_x6K02T2QD9B-18703033-18703986, MOR259-11, MOR259-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258265
Homologene: 134082
Rgl2
Name: ral guanine nucleotide dissociation stimulator-like 2
Synonyms: Rlf, KE1.5, Rab2l, Rgt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 19732
HGNC: HGNC:9769
Homologene: 3494
H6pd
Name: hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Synonyms: Gpd-1, Gpd1, G6pd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100198
HGNC: HGNC:4795
Homologene: 48275
Gja3
Name: gap junction protein, alpha 3
Synonyms: connexin 46, alpha 3 connexin, Gja-3, Cx46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 14611
VEGA: 14
HGNC: HGNC:4277
Homologene: 9670
Mgat5
Name: mannoside acetylglucosaminyltransferase 5
Synonyms: GlcNAc-TV, beta1,6N-acetylglucosaminyltransferase V, 5330407H02Rik, 4930471A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 107895
HGNC: HGNC:7049
Homologene: 1808
Fam166b
Name: family with sequence similarity 166, member B
Synonyms: 4833436C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329831
Homologene: 52229
Ndst1
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
Synonyms: glucosaminyl N-deacetylase/N-sulfotransferase 1, Hsst, 1200015G06Rik, Ndst-1, b2b2230Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 15531
VEGA: 18
HGNC: HGNC:7680
Homologene: 20386
Olfr807
Name: olfactory receptor 807
Synonyms: GA_x6K02T2PULF-11434134-11433199, MOR117-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258931
Homologene: 27300
Tsga10ip
Name: testis specific 10 interacting protein
Synonyms: 1810013N20Rik, Fam161c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 78306
VEGA: 19
Homologene: 17663
Tgfb2
Name: transforming growth factor, beta 2
Synonyms: Tgf-beta2, Tgfb-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21808
Homologene: 2432
1110032A03Rik
Name: RIKEN cDNA 1110032A03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68721
HGNC: HGNC:1163
Homologene: 11242
Abhd15
Name: abhydrolase domain containing 15
Synonyms: 1300007F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67477
Homologene: 12142
Dnajc5b
Name: DnaJ heat shock protein family (Hsp40) member C5 beta
Synonyms: 1700008A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66326
Homologene: 32634
Lrrc61
Name: leucine rich repeat containing 61
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243371
Homologene: 41538
Olfr9
Name: olfactory receptor 9
Synonyms: MOR269-3, GA_x6K02T2PULF-10675610-10676548
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18373
Homologene: 85121
Pmvk
Name: phosphomevalonate kinase
Synonyms: 1110011E12Rik, 2900002L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68603
HGNC: HGNC:9141
Homologene: 4779
Olfr550
Name: olfactory receptor 550
Synonyms: GA_x6K02T2PBJ9-5297243-5298193, MOR16-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259108
Homologene: 17507
Anapc15
Name: anaphase promoting complex C subunit 15
Synonyms: 6330414C15Rik, 3200002M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 75430
Homologene: 87047
Olfr485
Name: olfactory receptor 485
Synonyms: GA_x6K02T2PBJ9-10489044-10488091, MOR204-30P, MOR204-40_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258041
Homologene: 110483
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 127,459,921 bp
  • T to C, chromosome 1 at 136,171,143 bp
  • C to T, chromosome 1 at 186,649,741 bp
  • T to C, chromosome 2 at 73,348,248 bp
  • G to T, chromosome 2 at 94,425,688 bp
  • T to C, chromosome 2 at 127,256,145 bp
  • T to G, chromosome 2 at 163,865,843 bp
  • A to T, chromosome 3 at 19,574,782 bp
  • A to T, chromosome 3 at 36,638,370 bp
  • T to A, chromosome 3 at 38,891,627 bp
  • A to G, chromosome 3 at 39,010,378 bp
  • T to C, chromosome 3 at 89,468,571 bp
  • G to A, chromosome 3 at 97,562,616 bp
  • C to T, chromosome 4 at 43,427,687 bp
  • T to C, chromosome 4 at 118,829,666 bp
  • A to G, chromosome 4 at 149,981,784 bp
  • C to T, chromosome 5 at 135,367,476 bp
  • C to T, chromosome 5 at 137,835,770 bp
  • T to C, chromosome 5 at 149,214,746 bp
  • T to C, chromosome 5 at 150,793,597 bp
  • A to G, chromosome 6 at 18,319,059 bp
  • C to T, chromosome 6 at 35,512,290 bp
  • G to A, chromosome 6 at 48,568,374 bp
  • A to T, chromosome 7 at 18,612,072 bp
  • C to T, chromosome 7 at 101,898,603 bp
  • T to C, chromosome 7 at 102,579,274 bp
  • A to T, chromosome 7 at 108,159,273 bp
  • A to G, chromosome 7 at 131,316,074 bp
  • T to A, chromosome 8 at 13,066,854 bp
  • G to A, chromosome 8 at 84,235,079 bp
  • A to G, chromosome 8 at 85,878,245 bp
  • A to G, chromosome 8 at 122,386,902 bp
  • A to G, chromosome 9 at 21,829,548 bp
  • C to A, chromosome 9 at 50,765,749 bp
  • G to A, chromosome 10 at 99,445,147 bp
  • A to G, chromosome 10 at 128,990,679 bp
  • A to T, chromosome 10 at 129,754,534 bp
  • T to G, chromosome 11 at 33,642,389 bp
  • T to A, chromosome 11 at 77,518,839 bp
  • T to A, chromosome 11 at 78,265,208 bp
  • T to C, chromosome 11 at 83,189,229 bp
  • C to T, chromosome 11 at 115,984,157 bp
  • G to A, chromosome 13 at 59,791,852 bp
  • T to C, chromosome 13 at 93,083,273 bp
  • T to A, chromosome 13 at 113,318,765 bp
  • T to G, chromosome 14 at 57,035,832 bp
  • T to A, chromosome 14 at 61,193,514 bp
  • C to G, chromosome 15 at 55,642,795 bp
  • A to G, chromosome 15 at 75,708,205 bp
  • CGG to CGGG, chromosome 16 at 87,923,194 bp
  • G to T, chromosome 17 at 12,271,610 bp
  • A to G, chromosome 17 at 32,336,394 bp
  • A to T, chromosome 17 at 33,934,984 bp
  • A to G, chromosome 18 at 10,509,143 bp
  • A to T, chromosome 18 at 60,690,007 bp
  • A to T, chromosome 18 at 86,398,309 bp
  • A to T, chromosome 19 at 5,394,335 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5337 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042917-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.