Strain Name:
C57BL/6J-MtgxR5339Btlr/Mmmh
Stock Number:
042918-MU
Citation ID:
RRID:MMRRC_042918-MU
Other Names:
R5339 (G1), C57BL/6J-MtgxR5339Btlr
Major Collection:

Gene Information

Chrna7
Name: cholinergic receptor, nicotinic, alpha polypeptide 7
Synonyms: alpha7, alpha7 nicotinic receptor, alpha7-nAChR, Acra7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11441
HGNC: HGNC:1960
Homologene: 593
Fgfr1
Name: fibroblast growth factor receptor 1
Synonyms: Hspy, Flt-2, Eask, Fr1, FGFR-I, Fgfr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14182
HGNC: HGNC:3688
Homologene: 69065
Adgrl2
Name: adhesion G protein-coupled receptor L2
Synonyms: Lphh1, Lec1, Lphn2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99633
Homologene: 22712
Snx8
Name: sorting nexin 8
Synonyms: B130023O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231834
Homologene: 8338
Vps26a
Name: VPS26 retromer complex component A
Synonyms: H beta 58, Vps26, HB58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 30930
VEGA: 10
Homologene: 68420
Ipo5
Name: importin 5
Synonyms: 1110011C18Rik, RanBP5, 5730478E03Rik, Kpnb3, IMB3, importin beta 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 70572
VEGA: 14
HGNC: HGNC:6402
Homologene: 1710
Itpr1
Name: inositol 1,4,5-trisphosphate receptor 1
Synonyms: IP3R1, opt, Pcp1, wblo, Pcp-1, Ip3r, P400, InsP3R type I, Itpr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16438
HGNC: HGNC:6180
Homologene: 1673
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 21819
Homologene: 2430
Tep1
Name: telomerase associated protein 1
Synonyms: Tp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 21745
VEGA: 14
Homologene: 5157
Huwe1
Name: HECT, UBA and WWE domain containing 1
Synonyms: C430014N20Rik, Mule, Ureb1, Arf-bp1, Ib772, LOC382250, 5430439H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 59026
Homologene: 45994
Gfm2
Name: G elongation factor, mitochondrial 2
Synonyms: 6530419G12Rik, MST027, A930009M04Rik, EFG2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 320806
Homologene: 6238
Pex5
Name: peroxisomal biogenesis factor 5
Synonyms: ESTM1, PTS1R, peroxisome biogenesis factor 5, Pxr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 19305
HGNC: HGNC:9719
Homologene: 270
Kansl3
Name: KAT8 regulatory NSL complex subunit 3
Synonyms: 4632411B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226976
Homologene: 9949
Leng8
Name: leukocyte receptor cluster (LRC) member 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232798
Homologene: 13612
C3
Name: complement component 3
Synonyms: Plp, acylation stimulating protein, complement factor 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12266
HGNC: HGNC:1318
Homologene: 68031
Prune2
Name: prune homolog 2
Synonyms: 6330414G02Rik, A230083H22Rik, A330102H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 353211
VEGA: 19
Homologene: 18939
Pdia4
Name: protein disulfide isomerase associated 4
Synonyms: U48620, ERp72, Erp72, Cai
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12304
Homologene: 21020
Ccdc50
Name: coiled-coil domain containing 50
Synonyms: 5730448P06Rik, D16Bwg1543e, 2610529H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 67501
Homologene: 69406
Zfp236
Name: zinc finger protein 236
Synonyms: LOC240456
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 329002
Homologene: 7198
Crtc1
Name: CREB regulated transcription coactivator 1
Synonyms: TORC1, Mect1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 382056
Homologene: 41607
Pnpla7
Name: patatin-like phospholipase domain containing 7
Synonyms: E430013P11Rik, NRE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241274
Homologene: 62431
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 1110021D17Rik, 4833413O10Rik, Polydom, D430029O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 64817
Homologene: 23386
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Dnahc12, HL-19, DLP12, HL19, DHC3, 4921531P07Rik, Hdhc3, Dnahc7l, LOC380889
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Tbx15
Name: T-box 15
Synonyms: Tbx14, de, Tbx8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 21384
Homologene: 7967
Uba7
Name: ubiquitin-like modifier activating enzyme 7
Synonyms: 1300004C08Rik, Ube1l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74153
Homologene: 2502
Sycp2
Name: synaptonemal complex protein 2
Synonyms: 4930518F03Rik, 3830402K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 320558
Homologene: 8604
Klkb1
Name: kallikrein B, plasma 1
Synonyms: Klk3, PSA, Kal-3, Kal3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 16621
HGNC: HGNC:6371
Homologene: 68097
Ubqlnl
Name: ubiquilin-like
Synonyms: 4922504M18Rik, LOC244179
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244179
Homologene: 17034
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 215772
Homologene: 100289
Gm14085
Name: predicted gene 14085
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381417
Moxd2
Name: monooxygenase, DBH-like 2
Synonyms: Dbhl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 194357
Homologene: 77226
Olfr1361
Name: olfactory receptor 1361
Synonyms: GA_x6K02T2QHY8-11577590-11578528, MOR256-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 258534
Homologene: 88362
Foxa2
Name: forkhead box A2
Synonyms: Tcf-3b, HNF3-beta, HNF3beta, Hnf3b, Tcf3b, Hnf-3b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15376
HGNC: HGNC:5022
Homologene: 7762
Olfr948
Name: olfactory receptor 948
Synonyms: MOR171-45, MOR171-51, GA_x6K02T2PVTD-33016899-33015934
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 257912
VEGA: 9
Homologene: 79377
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: Opo, ojoplano
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218165
VEGA: 13
Homologene: 125376
Mctp1
Name: multiple C2 domains, transmembrane 1
Synonyms: 2810465F10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 78771
Homologene: 75211
Zfp800
Name: zinc finger protein 800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 627049
Homologene: 18529
Gzmd
Name: granzyme D
Synonyms: Ctla5, CCP5, Ctla-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 14941
HGNC: HGNC:4710
Homologene: 133275
Ublcp1
Name: ubiquitin-like domain containing CTD phosphatase 1
Synonyms: 8430435I17Rik, 4930527B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 79560
Homologene: 16796
Sstr5
Name: somatostatin receptor 5
Synonyms: sst5, Smstr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20609
VEGA: 17
Homologene: 20287
Tdrd9
Name: tudor domain containing 9
Synonyms: 4930441E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 74691
Homologene: 14311
Tha1
Name: threonine aldolase 1
Synonyms: 1300017K07Rik, GLY1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71776
Homologene: 57081
Olfr845
Name: olfactory receptor 845
Synonyms: GA_x6K02T2PVTD-13076685-13077623, Olfr1522-ps1, MOR150-2, MOR150-1P, MOR150-1P, MOR150-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258249
Homologene: 133689
Ehd3
Name: EH-domain containing 3
Synonyms: Ehd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 57440
HGNC: HGNC:3244
Homologene: 81837
Fastkd3
Name: FAST kinase domains 3
Synonyms: 2310010B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 69577
VEGA: 13
Homologene: 11457
Slbp
Name: stem-loop binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 20492
Homologene: 31389
Olfr970
Name: olfactory receptor 970
Synonyms: MOR171-16, GA_x6K02T2PVTD-33517322-33518257
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258604
VEGA: 9
Homologene: 121532
Trim72
Name: tripartite motif-containing 72
Synonyms: mitsugumin 53, MG53
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 434246
Homologene: 66924
Krtap14
Name: keratin associated protein 14
Synonyms: mKAP13, Pmg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 23927
Homologene: 56600
Gm1968
Name: predicted gene 1968
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 328657
VEGA: 16
Olfr728
Name: olfactory receptor 728
Synonyms: GA_x6K02T2PMLR-5831021-5830086, MOR246-1P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258039
Homologene: 74224
Reg3a
Name: regenerating islet-derived 3 alpha
Synonyms: RegIII (alpha)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 19694
HGNC: HGNC:8601
Homologene: 136247
Zdhhc21
Name: zinc finger, DHHC domain containing 21
Synonyms: 9130404H11Rik, D130004H04Rik, dep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68268
Homologene: 32668
Gmfg-ps
Name: glia maturation factor, gamma, pseudogene
Synonyms: Gm9835
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 100040018
HGNC: HGNC:4374
Homologene: 37978
Hist3h2bb-ps
Name: histone cluster 3, H2bb, pseudogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 382522
Homologene: 75941
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 36,367,721 bp
  • T to C, chromosome 2 at 25,002,937 bp
  • A to T, chromosome 2 at 122,486,671 bp
  • T to A, chromosome 2 at 148,044,434 bp
  • A to G, chromosome 2 at 178,362,979 bp
  • G to A, chromosome 3 at 99,316,284 bp
  • C to T, chromosome 3 at 148,817,844 bp
  • T to C, chromosome 4 at 58,121,892 bp
  • C to T, chromosome 4 at 82,838,313 bp
  • A to G, chromosome 5 at 33,643,748 bp
  • G to A, chromosome 5 at 140,358,150 bp
  • T to C, chromosome 6 at 4,893,401 bp
  • A to T, chromosome 6 at 28,256,473 bp
  • T to C, chromosome 6 at 40,885,420 bp
  • C to T, chromosome 6 at 47,796,685 bp
  • A to G, chromosome 6 at 78,383,539 bp
  • T to A, chromosome 6 at 108,393,961 bp
  • A to T, chromosome 6 at 124,398,004 bp
  • T to A, chromosome 7 at 4,145,286 bp
  • A to G, chromosome 7 at 63,099,307 bp
  • A to G, chromosome 7 at 104,149,765 bp
  • A to G, chromosome 7 at 128,010,333 bp
  • T to C, chromosome 8 at 25,564,408 bp
  • C to A, chromosome 8 at 45,270,711 bp
  • A to T, chromosome 8 at 70,397,733 bp
  • G to A, chromosome 9 at 19,339,159 bp
  • A to T, chromosome 9 at 39,319,303 bp
  • T to A, chromosome 9 at 39,819,933 bp
  • C to T, chromosome 9 at 107,978,866 bp
  • C to T, chromosome 10 at 10,442,606 bp
  • A to G, chromosome 10 at 62,458,967 bp
  • A to T, chromosome 11 at 44,455,608 bp
  • C to T, chromosome 11 at 58,954,510 bp
  • C to A, chromosome 11 at 117,871,082 bp
  • T to C, chromosome 12 at 112,027,122 bp
  • G to A, chromosome 13 at 21,659,234 bp
  • A to G, chromosome 13 at 40,087,845 bp
  • G to A, chromosome 13 at 68,590,164 bp
  • C to A, chromosome 13 at 76,825,706 bp
  • T to C, chromosome 13 at 97,175,040 bp
  • A to G, chromosome 14 at 26,814,537 bp
  • C to A, chromosome 14 at 50,140,302 bp
  • A to T, chromosome 14 at 50,844,574 bp
  • A to T, chromosome 14 at 56,130,683 bp
  • T to C, chromosome 14 at 120,943,710 bp
  • T to A, chromosome 15 at 66,678,093 bp
  • C to T, chromosome 16 at 27,417,305 bp
  • T to C, chromosome 16 at 29,962,259 bp
  • A to C, chromosome 16 at 32,753,917 bp
  • C to A, chromosome 16 at 88,825,859 bp
  • T to C, chromosome 17 at 25,491,199 bp
  • C to A, chromosome 17 at 57,224,308 bp
  • G to A, chromosome 17 at 73,828,207 bp
  • T to C, chromosome 18 at 82,624,366 bp
  • G to A, chromosome 19 at 17,120,872 bp
  • AGAGGAGGAGGAGGAGGA to AGAGGAGGAGGAGGA, chromosome X at 151,907,048 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5339 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042918-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.