Strain Name:
C57BL/6J-MtgxR5354Btlr/Mmmh
Stock Number:
042933-MU
Citation ID:
RRID:MMRRC_042933-MU
Other Names:
R5354 (G1), C57BL/6J-MtgxR5354Btlr
Major Collection:

Gene Information

Pald1
Name: phosphatase domain containing, paladin 1
Synonyms: paladin, X99384
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 27355
VEGA: 10
Homologene: 8453
Slc6a1
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 1
Synonyms: XT-1, Gabt, Xtrp1, Gat1, Gabt1, GAT-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232333
Homologene: 2290
Slit3
Name: slit guidance ligand 3
Synonyms: Slit1, b2b2362.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20564
Homologene: 2303
Thbs3
Name: thrombospondin 3
Synonyms: Thbs-3, TSP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 21827
Homologene: 5159
Bclaf1
Name: BCL2-associated transcription factor 1
Synonyms: 2700025J07Rik, 2810454G14Rik, 2610102K23Rik, 5730534O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 72567
Homologene: 8832
Wnk1
Name: WNK lysine deficient protein kinase 1
Synonyms: 6430573H23Rik, Prkwnk1, EG406236, Hsn2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232341
Homologene: 14253
Hmgcr
Name: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Synonyms: HMG-CoAR, 3-hydroxy-3-methylglutaryl-CoA reductase, Red
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 15357
HGNC: HGNC:5006
Homologene: 30994
Dhx38
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 38
Synonyms: Prp16, Ddx38, 5730550P09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 64340
Homologene: 8512
Ints1
Name: integrator complex subunit 1
Synonyms: 1110015K06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 68510
Homologene: 53111
Dctn1
Name: dynactin 1
Synonyms: Glued, p150, p150glued
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 13191
HGNC: HGNC:2711
Homologene: 3011
Tpr
Name: translocated promoter region, nuclear basket protein
Synonyms: 2610029M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108989
Homologene: 37753
Nufip2
Name: nuclear fragile X mental retardation protein interacting protein 2
Synonyms: 9530056D24Rik, 1110001M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 68564
Homologene: 10808
Uhrf1bp1
Name: UHRF1 (ICBP90) binding protein 1
Synonyms: 1110020K19Rik, F830021D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224648
Homologene: 9816
Coro1c
Name: coronin, actin binding protein 1C
Synonyms: coronin 3, CRN2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 23790
HGNC: HGNC:2254
Homologene: 56537
Son
Name: Son DNA binding protein
Synonyms: 2900011L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20658
Homologene: 10551
Cdc45
Name: cell division cycle 45
Synonyms: Cdc45l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12544
HGNC: HGNC:1739
Homologene: 2616
Snap91
Name: synaptosomal-associated protein 91
Synonyms: F1-20, 91kDa, AP180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20616
Homologene: 8429
Aco1
Name: aconitase 1
Synonyms: Irp1, Irebp, Aco-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11428
HGNC: HGNC:117
Homologene: 1657
Bod1l
Name: biorientation of chromosomes in cell division 1-like
Synonyms: A230054D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 665775
Homologene: 45109
Gm14496
Name: predicted gene 14496
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 672125
Homologene: 129606
Fchsd1
Name: FCH and double SH3 domains 1
Synonyms: A030002D08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 319262
Homologene: 14127
Anxa7
Name: annexin A7
Synonyms: synexin, Anx7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 11750
VEGA: 14
HGNC: HGNC:545
Homologene: 36149
Ckap2
Name: cytoskeleton associated protein 2
Synonyms: LB1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 80986
HGNC: HGNC:1990
Homologene: 10070
Ppp4r3b
Name: protein phosphatase 4 regulatory subunit 3B
Synonyms: Smek2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 104570
Homologene: 68886
Zbtb7b
Name: zinc finger and BTB domain containing 7B
Synonyms: c-Krox, Zfp67, Thpok
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 22724
Homologene: 7605
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26875
Homologene: 69111
Egfem1
Name: EGF-like and EMI domain containing 1
Synonyms: 6130401L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 75740
Homologene: 135950
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Hdhc3, HL-19, DLP12, HL19, DHC3, LOC380889, 4921531P07Rik, Dnahc7l, Dnahc12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Pde10a
Name: phosphodiesterase 10A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 23984
HGNC: HGNC:8772
Homologene: 4852
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22635
Homologene: 124417
Rims1
Name: regulating synaptic membrane exocytosis 1
Synonyms: RIM1, RIM1a, C030033M19Rik, RIM1alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 116837
Homologene: 128399
Agbl3
Name: ATP/GTP binding protein-like 3
Synonyms: 2900053G10Rik, 6530406M24Rik, 4930431N21Rik, Ccp3, Ccp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 76223
Homologene: 35330
Pcdhb13
Name: protocadherin beta 13
Synonyms: PcdhbM, Pcdbh6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93884
HGNC: HGNC:8691
Homologene: 10338
Skint10
Name: selection and upkeep of intraepithelial T cells 10
Synonyms: A030001H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230613
Homologene: 136292
Gpat2
Name: glycerol-3-phosphate acyltransferase 2, mitochondrial
Synonyms: Gpat2, A530057A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 215456
Homologene: 19037
Trp63
Name: transformation related protein 63
Synonyms: KET protein, p63, p73L, Trp53rp1, TAp63, p51/p63, deltaNp63
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22061
Homologene: 31189
Myh4
Name: myosin, heavy polypeptide 4, skeletal muscle
Synonyms: MyHC-IIb, MHC2B, Myhsf, MM, MYH-2B, Minmus, Minimsc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17884
HGNC: HGNC:7574
Homologene: 123880
St18
Name: suppression of tumorigenicity 18
Synonyms: Nzf3, Myt3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240690
Homologene: 8792
Ablim1
Name: actin-binding LIM protein 1
Synonyms: Limab1, 4833406P10Rik, abLIM-S, abLIM-M, abLIM-L, 2610209L21Rik, 9330196J19Rik, 2210411C18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226251
HGNC: HGNC:78
Homologene: 40994
Dnajb7
Name: DnaJ heat shock protein family (Hsp40) member B7
Synonyms: mDj5, 4933424H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 57755
Homologene: 77343
Vmn1r27
Name: vomeronasal 1 receptor 27
Synonyms: V1rc33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171206
Homologene: 79462
Ccdc170
Name: coiled-coil domain containing 170
Synonyms: LOC237250, Gm221
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100504234
Homologene: 69393
Atp11a
Name: ATPase, class VI, type 11A
Synonyms: Ih, 4930558F19Rik, 9130422H11Rik, LOC100045280
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 50770
Homologene: 75050
Med16
Name: mediator complex subunit 16
Synonyms: 95kDa, Trap95, Thrap5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216154
Homologene: 64602
Adam22
Name: a disintegrin and metallopeptidase domain 22
Synonyms: MDC2, 2900022I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11496
HGNC: HGNC:201
Homologene: 37898
Xkr6
Name: X-linked Kx blood group related 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219149
Homologene: 18287
Olfr414
Name: olfactory receptor 414
Synonyms: GA_x6K02T2P20D-20749615-20748662, MOR103-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258756
Homologene: 17383
Clca3a1
Name: chloride channel accessory 3A1
Synonyms: Clca1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12722
Homologene: 77224
Slc28a3
Name: solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
Synonyms: Cnt3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 114304
Homologene: 32533
Fmo1
Name: flavin containing monooxygenase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14261
HGNC: HGNC:3769
Homologene: 55520
Zfp618
Name: zinc finger protein 618
Synonyms: D430033D05Rik, 2810040O04Rik, 2810031P15Rik, Nedd10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 72701
Homologene: 18975
Olfr290
Name: olfactory receptor 290
Synonyms: GA_x6K02T2NHDJ-11170115-11169168, MOR254-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258411
Homologene: 83130
Pnpt1
Name: polyribonucleotide nucleotidyltransferase 1
Synonyms: PNPase, polynucleotide phosphorylase, 1200003F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71701
Homologene: 12404
Bcas1
Name: breast carcinoma amplified sequence 1
Synonyms: NABC1, 2210416M21Rik, 9030223A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 76960
HGNC: HGNC:974
Homologene: 2714
Catsperg1
Name: cation channel sperm associated auxiliary subunit gamma 1
Synonyms: A230107C01Rik, Catsperg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 320225
Homologene: 10915
Cyp4a12b
Name: cytochrome P450, family 4, subfamily a, polypeptide 12B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13118
Homologene: 134044
Plin1
Name: perilipin 1
Synonyms: 6030432J05Rik, perilipin B, perilipin A, Peri, Plin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 103968
HGNC: HGNC:9076
Homologene: 2001
Cpox
Name: coproporphyrinogen oxidase
Synonyms: clone 560, cac, Cpo, nct
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12892
VEGA: 16
HGNC: HGNC:2321
Homologene: 76
Dsc1
Name: desmocollin 1
Synonyms: Dsc1b, Dsc1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13505
VEGA: 18
HGNC: HGNC:3035
Homologene: 22761
Synpo
Name: synaptopodin
Synonyms: 9330140I15Rik, 9030217H17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 104027
Homologene: 5274
Rassf5
Name: Ras association (RalGDS/AF-6) domain family member 5
Synonyms: 1300019G20Rik, Nore1B, Nore1A, Rapl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 54354
Homologene: 10296
Pcsk4
Name: proprotein convertase subtilisin/kexin type 4
Synonyms: PC4, SPC5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18551
HGNC: HGNC:8746
Homologene: 22495
Acat1
Name: acetyl-Coenzyme A acetyltransferase 1
Synonyms: Acat, 6330585C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 110446
HGNC: HGNC:93
Homologene: 6
A630010A05Rik
Name: RIKEN cDNA A630010A05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 545280
Mrgprb4
Name: MAS-related GPR, member B4
Synonyms: MrgB4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233230
Homologene: 115575
Psmc3
Name: proteasome (prosome, macropain) 26S subunit, ATPase 3
Synonyms: Tat binding protein 1, TBP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19182
HGNC: HGNC:9549
Homologene: 2097
Hax1
Name: HCLS1 associated X-1
Synonyms: mHAX-1s, HAX-1, Silg111, Hs1bp1, HS1-associated protein X-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 23897
Homologene: 4463
Gpr162
Name: G protein-coupled receptor 162
Synonyms: A-2, Grca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14788
Homologene: 8400
Islr
Name: immunoglobulin superfamily containing leucine-rich repeat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 26968
VEGA: 9
HGNC: HGNC:6133
Homologene: 4050
Plekhg2
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 2
Synonyms: Clg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101497
Homologene: 16341
Lrrc36
Name: leucine rich repeat containing 36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 270091
Homologene: 23090
Oasl1
Name: 2'-5' oligoadenylate synthetase-like 1
Synonyms: 7530414C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231655
HGNC: HGNC:8090
Homologene: 2769
Hsd3b2
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 15493
Homologene: 133013
Dupd1
Name: dual specificity phosphatase and pro isomerase domain containing 1
Synonyms: EG435391
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 435391
VEGA: 14
Homologene: 51120
Maf1
Name: MAF1 homolog, negative regulator of RNA polymerase III
Synonyms: 1110068E11Rik, Maf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 68877
Homologene: 49867
Pcdhga10
Name: protocadherin gamma subfamily A, 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93722
HGNC: HGNC:8697
Homologene: 49567
Gm10237
Name: predicted gene 10237
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 108168272
VEGA: 16
Prr18
Name: proline rich 18
Synonyms: 9630019K15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 320111
VEGA: 17
Homologene: 52195
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 6,844,171 bp
  • T to A, chromosome 1 at 22,538,511 bp
  • T to C, chromosome 1 at 131,180,648 bp
  • C to T, chromosome 1 at 150,445,924 bp
  • T to C, chromosome 1 at 162,830,145 bp
  • T to C, chromosome 1 at 174,430,686 bp
  • T to A, chromosome 2 at 91,059,353 bp
  • T to A, chromosome 2 at 127,428,723 bp
  • T to A, chromosome 2 at 170,349,396 bp
  • A to G, chromosome 2 at 182,000,809 bp
  • T to C, chromosome 3 at 29,082,212 bp
  • A to G, chromosome 3 at 89,221,377 bp
  • T to C, chromosome 3 at 89,379,606 bp
  • A to T, chromosome 3 at 89,997,955 bp
  • T to C, chromosome 3 at 98,712,315 bp
  • A to T, chromosome 3 at 144,737,005 bp
  • T to C, chromosome 4 at 40,180,290 bp
  • A to T, chromosome 4 at 63,080,028 bp
  • T to C, chromosome 4 at 112,711,593 bp
  • C to A, chromosome 4 at 115,433,464 bp
  • C to A, chromosome 5 at 8,090,182 bp
  • C to A, chromosome 5 at 14,678,808 bp
  • A to C, chromosome 5 at 41,831,537 bp
  • A to T, chromosome 5 at 113,846,165 bp
  • A to T, chromosome 5 at 114,936,996 bp
  • A to G, chromosome 5 at 137,380,788 bp
  • A to G, chromosome 5 at 139,766,428 bp
  • T to A, chromosome 6 at 34,814,752 bp
  • C to A, chromosome 6 at 58,215,596 bp
  • T to G, chromosome 6 at 83,183,126 bp
  • T to C, chromosome 6 at 114,302,623 bp
  • T to C, chromosome 6 at 119,968,523 bp
  • T to C, chromosome 6 at 124,859,637 bp
  • T to C, chromosome 7 at 28,362,274 bp
  • G to T, chromosome 7 at 29,195,873 bp
  • T to A, chromosome 7 at 48,198,329 bp
  • T to A, chromosome 7 at 79,725,721 bp
  • T to A, chromosome 7 at 84,916,149 bp
  • A to T, chromosome 8 at 12,806,753 bp
  • A to C, chromosome 8 at 22,177,565 bp
  • A to G, chromosome 8 at 105,425,364 bp
  • A to G, chromosome 8 at 109,555,746 bp
  • T to A, chromosome 9 at 53,589,183 bp
  • T to C, chromosome 9 at 58,157,612 bp
  • C to T, chromosome 9 at 86,835,124 bp
  • G to A, chromosome 10 at 4,534,188 bp
  • A to G, chromosome 10 at 20,333,532 bp
  • A to T, chromosome 10 at 61,348,661 bp
  • T to C, chromosome 10 at 79,898,396 bp
  • G to T, chromosome 10 at 80,323,689 bp
  • A to G, chromosome 11 at 29,154,166 bp
  • T to A, chromosome 11 at 29,211,646 bp
  • A to G, chromosome 11 at 35,675,913 bp
  • A to T, chromosome 11 at 67,255,725 bp
  • A to G, chromosome 11 at 77,686,277 bp
  • G to C, chromosome 13 at 58,610,778 bp
  • C to T, chromosome 13 at 96,654,896 bp
  • A to G, chromosome 14 at 20,464,909 bp
  • G to A, chromosome 14 at 21,677,023 bp
  • G to A, chromosome 14 at 26,774,342 bp
  • A to G, chromosome 14 at 63,818,904 bp
  • T to C, chromosome 15 at 76,353,130 bp
  • T to C, chromosome 15 at 81,408,007 bp
  • A to G, chromosome 16 at 14,618,671 bp
  • C to T, chromosome 16 at 18,795,897 bp
  • A to G, chromosome 16 at 25,684,355 bp
  • T to C, chromosome 16 at 35,920,729 bp
  • A to G, chromosome 16 at 58,670,842 bp
  • T to C, chromosome 16 at 91,655,739 bp
  • C to A, chromosome 17 at 8,341,060 bp
  • C to A, chromosome 17 at 8,961,980 bp
  • G to A, chromosome 17 at 27,887,515 bp
  • A to T, chromosome 18 at 20,087,575 bp
  • G to T, chromosome 18 at 37,444,791 bp
  • A to G, chromosome 18 at 37,748,206 bp
  • C to T, chromosome 18 at 37,959,873 bp
  • A to G, chromosome 18 at 60,602,231 bp
  • T to C, chromosome 19 at 57,130,923 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5354 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042933-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.