Strain Name:
C57BL/6J-MtgxR5408Btlr/Mmmh
Stock Number:
042977-MU
Citation ID:
RRID:MMRRC_042977-MU
Other Names:
R5408 (G1), C57BL/6J-MtgxR5408Btlr
Major Collection:

Strain Information

Cdh3
Name: cadherin 3
Synonyms: Cadp, P-cadherin, Pcad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12560
HGNC: HGNC:1762
Homologene: 20425
Ptprz1
Name: protein tyrosine phosphatase receptor type Z, polypeptide 1
Synonyms: DSD-1-PG, Ptprz, Ptpz, Rptpbeta, PTPbeta, PTPzeta, RPTPz, phosphacan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Cadps
Name: Ca2+-dependent secretion activator
Synonyms: CAPS1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 27062
VEGA: 14
HGNC: HGNC:1426
Homologene: 2755
Blm
Name: Bloom syndrome, RecQ like helicase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12144
HGNC: HGNC:1058
Homologene: 47902
Epb41l2
Name: erythrocyte membrane protein band 4.1 like 2
Synonyms: Epb4.1l2, 4.1G, D10Ertd398e, NBL2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13822
VEGA: 10
HGNC: HGNC:3379
Homologene: 37478
Kif13b
Name: kinesin family member 13B
Synonyms: C130021D12Rik, 5330429L19Rik, N-3 kinesin, GAKIN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16554
VEGA: 14
Homologene: 9073
Akap9
Name: A kinase (PRKA) anchor protein (yotiao) 9
Synonyms: AKAP450, repro12, mei2-5, 5730481H23Rik, G1-448-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Scaper
Name: S phase cyclin A-associated protein in the ER
Synonyms: D530014O03Rik, Zfp291
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244891
VEGA: 9
Homologene: 32488
Gspt1
Name: G1 to S phase transition 1
Synonyms: Gst-1, G1st, Gst-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 14852
HGNC: HGNC:4621
Homologene: 68226
Gtf2ird1
Name: general transcription factor II I repeat domain-containing 1
Synonyms: WBSCR11, binding factor for early enhancer, Cream1, GTF3, ESTM9, MusTRD1, BEN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 57080
HGNC: HGNC:4661
Homologene: 4158
Atp13a1
Name: ATPase type 13A1
Synonyms: Cgi152, catp, Atp13a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 170759
VEGA: 8
Homologene: 5791
Psip1
Name: PC4 and SFRS1 interacting protein 1
Synonyms: Psip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 101739
HGNC: HGNC:9527
Homologene: 13242
Son
Name: Son DNA binding protein
Synonyms: 2900011L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20658
Homologene: 10551
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: 8030453L17Rik, E430018P19Rik, KMT2H, chromatin remodeling factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 192195
Homologene: 10225
Shoc2
Name: Shoc2, leucine rich repeat scaffold protein
Synonyms: Sur-8, soc-2 (suppressor of clear) homolog (C. elegans)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 56392
VEGA: 19
Homologene: 7219
Uty
Name: ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
Synonyms: Hydb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
NCBI: 22290
Rreb1
Name: ras responsive element binding protein 1
Synonyms: 1110037N09Rik, B930013M22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 68750
Homologene: 2218
Jup
Name: junction plakoglobin
Synonyms: PG, gamma-catenin, D930025P04Rik, Ctnng, plakoglobin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16480
HGNC: HGNC:6207
Homologene: 1680
Bend5
Name: BEN domain containing 5
Synonyms: 2310026E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67621
Homologene: 41574
Nbeal2
Name: neurobeachin-like 2
Synonyms: 1110014F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235627
Homologene: 86422
Baz1a
Name: bromodomain adjacent to zinc finger domain 1A
Synonyms: Acf1, Gtl5, Wcrf180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217578
HGNC: HGNC:960
Homologene: 45654
Usp54
Name: ubiquitin specific peptidase 54
Synonyms: 4930429G18Rik, C030002J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 78787
Homologene: 90902
Fchsd2
Name: FCH and double SH3 domains 2
Synonyms: Sh3md3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 207278
Homologene: 8887
Olfml2b
Name: olfactomedin-like 2B
Synonyms: 4832415H08Rik, 1110018N05Rik, photomedin-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 320078
Homologene: 18546
Uncx
Name: UNC homeobox
Synonyms: Uncx4.1, Chx4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22255
Homologene: 56598
Galnt12
Name: polypeptide N-acetylgalactosaminyltransferase 12
Synonyms: A630062B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230145
Homologene: 11637
Kcng3
Name: potassium voltage-gated channel, subfamily G, member 3
Synonyms: KV6.3, Kv10.1a, Kv10.1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225030
VEGA: 17
Homologene: 15168
Nr1d1
Name: nuclear receptor subfamily 1, group D, member 1
Synonyms: rev-erbA(alpha), REV-ERBalpha, A530070C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217166
HGNC: HGNC:7962
Homologene: 23324
Cacna1a
Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Synonyms: alpha1A, Ccha1a, SCA6, Cacnl1a4, nmf352, smrl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12286
HGNC: HGNC:1388
Homologene: 56383
Ank1
Name: ankyrin 1, erythroid
Synonyms: pale, Ank-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11733
HGNC: HGNC:492
Homologene: 55427
Mapk3
Name: mitogen-activated protein kinase 3
Synonyms: Esrk1, Erk1, Prkm3, Mtap2k, p44mapk, p44erk1, Erk-1, p44 MAP kinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26417
HGNC: HGNC:6877
Homologene: 55682
Slc7a2
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
Synonyms: Cat2, Tea, Atrc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11988
Homologene: 20659
Ttn
Name: titin
Synonyms: L56, 1100001C23Rik, D330041I19Rik, 2310057K23Rik, D830007G01Rik, 2310074I15Rik, 2310036G12Rik, mdm, connectin, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Pkd1l3
Name: polycystic kidney disease 1 like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244646
Homologene: 14627
Fyco1
Name: FYVE and coiled-coil domain containing 1
Synonyms: 2810409M01Rik, ZFYVE7, Mem2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17281
Homologene: 11561
Scyl3
Name: SCY1-like 3 (S. cerevisiae)
Synonyms: Pace1, 1200016D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240880
Homologene: 10706
Reg3b
Name: regenerating islet-derived 3 beta
Synonyms: REG-III, Pap, PAP1, RegIII (beta)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 18489
Homologene: 130506
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Trim14
Name: tripartite motif-containing 14
Synonyms: 5830400N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 74735
Homologene: 13241
Actn2
Name: actinin alpha 2
Synonyms: 1110008F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 11472
HGNC: HGNC:164
Homologene: 31016
Mmp3
Name: matrix metallopeptidase 3
Synonyms: stromelysin 1, Str1, Stmy1, SLN-1, SLN1, progelatinase, STR-1, stromelysin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17392
VEGA: 9
HGNC: HGNC:7173
Homologene: 20545
Xcr1
Name: chemokine (C motif) receptor 1
Synonyms: C motif-1/lymphotactin receptor, XCR1, Ccxcr1, GPR5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 23832
HGNC: HGNC:1625
Homologene: 21095
Akr1c13
Name: aldo-keto reductase family 1, member C13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 27384
Homologene: 121208
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: Usmg4, D130016K21Rik, 9430063L05Rik, D3Bwg1078e, 4732458A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 83679
Homologene: 66961
Pip4k2a
Name: phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
Synonyms: Pip5k2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18718
HGNC: HGNC:8997
Homologene: 37995
Padi6
Name: peptidyl arginine deiminase, type VI
Synonyms: Padi5, ePAD, Pad6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242726
Homologene: 17695
Fam171a2
Name: family with sequence similarity 171, member A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217219
Homologene: 19144
Dgkz
Name: diacylglycerol kinase zeta
Synonyms: E130307B02Rik, mDGK[z]
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 104418
HGNC: HGNC:2857
Homologene: 37831
Sox30
Name: SRY (sex determining region Y)-box 30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 214105
Homologene: 34027
Wdsub1
Name: WD repeat, SAM and U-box domain containing 1
Synonyms: 2610014F08Rik, 1700048E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72137
Homologene: 17609
Col16a1
Name: collagen, type XVI, alpha 1
Synonyms: A530052M23Rik, 2700007F12Rik, [a]1 (XVI) collagen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 107581
HGNC: HGNC:2193
Homologene: 1397
Cacna2d4
Name: calcium channel, voltage-dependent, alpha 2/delta subunit 4
Synonyms: 5730412N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 319734
Homologene: 26544
Prex1
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Synonyms: P-REX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 277360
Homologene: 10821
Wipf3
Name: WAS/WASL interacting protein family, member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330319
Homologene: 113391
Zfp687
Name: zinc finger protein 687
Synonyms: 4931408L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 78266
Homologene: 10827
Or56b1b
Name: olfactory receptor family 56 subfamily B member 1B
Synonyms: MOR40-7P, Olfr504, GA_x6K02T2PBJ9-10895499-10894543, MOR40-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258163
Homologene: 17189
A430110L20Rik
Name: RIKEN cDNA A430110L20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Vmn1r30
Name: vomeronasal 1 receptor 30
Synonyms: V1rc22, V1rc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 171195
Homologene: 137652
H6pd
Name: hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Synonyms: G6pd1, Gpd1, Gpd-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100198
HGNC: HGNC:4795
Homologene: 48275
Hectd2
Name: HECT domain E3 ubiquitin protein ligase 2
Synonyms: A630025O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226098
Homologene: 6280
Higd1c
Name: HIG1 domain family, member 1C
Synonyms: LOC380975, Yghl1-4, HIG1-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 380975
Homologene: 105259
Zswim9
Name: zinc finger SWIM-type containing 9
Synonyms: 6330408A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 321008
Homologene: 52386
Aldh2
Name: aldehyde dehydrogenase 2, mitochondrial
Synonyms: Ahd5, Ahd-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11669
HGNC: HGNC:404
Homologene: 55480
Or13p4
Name: olfactory receptor family 13 subfamily P member 4
Synonyms: Olfr1342, GA_x6K02T2QD9B-18856980-18857927, MOR258-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258708
Homologene: 17357
Zhx1
Name: zinc fingers and homeoboxes 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22770
Homologene: 5225
Pcyox1
Name: prenylcysteine oxidase 1
Synonyms: PCL1, 1200015P13Rik, Pcly
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66881
Homologene: 9458
Fam89b
Name: family with sequence similarity 89, member B
Synonyms: Mtvr2, 1110021A21Rik, Fam89b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 17826
Homologene: 18749
Cfap68
Name: cilia and flagella associated protein 68
Synonyms: 1110032A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68721
HGNC: HGNC:1163
Homologene: 11242
Cenps
Name: centromere protein S
Synonyms: 2810407L01Rik, 2610040C18Rik, Apitd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69928
Homologene: 66004
Dctn6
Name: dynactin 6
Synonyms: WS-3, p27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 22428
Homologene: 4792
Sap18
Name: Sin3-associated polypeptide 18
Synonyms: Sinbp1, C530046K05Rik, Sap18a, EMegR4, D11Ertd539e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 20220
Homologene: 4289
Adora1
Name: adenosine A1 receptor
Synonyms: A1R, A1AR, Ri, AA1R, A1-AR, ARA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11539
HGNC: HGNC:262
Homologene: 20165
Gm11505
Name: predicted gene 11505
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Zfp729b
Name: zinc finger protein 729b
Synonyms: AA987161
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 100416706
Homologene: 133713
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 134,203,163 bp
  • A to T, chromosome 1 at 163,954,676 bp
  • T to A, chromosome 1 at 170,644,976 bp
  • A to G, chromosome 1 at 181,227,414 bp
  • T to C, chromosome 2 at 18,906,308 bp
  • T to C, chromosome 2 at 59,861,543 bp
  • T to C, chromosome 2 at 76,900,928 bp
  • C to A, chromosome 2 at 91,935,823 bp
  • CGTTGTTGTTGT to CGTTGTTGTTGTTGT, chromosome 2 at 166,575,653 bp
  • A to G, chromosome 3 at 88,982,394 bp
  • T to C, chromosome 3 at 95,009,275 bp
  • T to A, chromosome 3 at 97,796,736 bp
  • A to T, chromosome 4 at 46,507,134 bp
  • A to T, chromosome 4 at 47,104,169 bp
  • T to C, chromosome 4 at 83,458,137 bp
  • A to T, chromosome 4 at 111,454,083 bp
  • T to C, chromosome 4 at 118,690,444 bp
  • A to T, chromosome 4 at 130,093,105 bp
  • G to A, chromosome 4 at 140,727,685 bp
  • C to A, chromosome 4 at 149,130,201 bp
  • A to G, chromosome 4 at 149,982,865 bp
  • T to A, chromosome 5 at 4,058,458 bp
  • C to T, chromosome 5 at 121,570,557 bp
  • T to C, chromosome 5 at 134,362,468 bp
  • A to T, chromosome 5 at 139,544,490 bp
  • C to T, chromosome 6 at 23,002,600 bp
  • A to G, chromosome 6 at 54,481,911 bp
  • C to T, chromosome 6 at 58,435,044 bp
  • T to C, chromosome 6 at 78,373,232 bp
  • A to G, chromosome 6 at 86,392,298 bp
  • A to G, chromosome 6 at 119,348,791 bp
  • T to C, chromosome 7 at 13,260,826 bp
  • T to G, chromosome 7 at 80,502,622 bp
  • A to G, chromosome 7 at 101,271,574 bp
  • C to T, chromosome 7 at 108,565,169 bp
  • A to G, chromosome 7 at 126,763,835 bp
  • A to G, chromosome 8 at 23,082,193 bp
  • C to T, chromosome 8 at 34,094,902 bp
  • G to A, chromosome 8 at 40,915,005 bp
  • T to C, chromosome 8 at 69,796,840 bp
  • T to C, chromosome 8 at 84,549,707 bp
  • T to C, chromosome 8 at 106,536,637 bp
  • C to A, chromosome 8 at 109,667,052 bp
  • T to C, chromosome 9 at 7,449,904 bp
  • T to C, chromosome 9 at 50,764,757 bp
  • A to T, chromosome 9 at 55,586,224 bp
  • C to A, chromosome 9 at 110,637,520 bp
  • T to G, chromosome 9 at 123,829,503 bp
  • T to A, chromosome 9 at 123,856,566 bp
  • A to T, chromosome 10 at 25,468,094 bp
  • A to G, chromosome 11 at 45,991,867 bp
  • A to G, chromosome 11 at 59,051,611 bp
  • T to A, chromosome 11 at 87,801,025 bp
  • T to A, chromosome 11 at 98,770,261 bp
  • C to T, chromosome 11 at 100,376,781 bp
  • T to C, chromosome 11 at 102,437,518 bp
  • A to T, chromosome 12 at 54,923,050 bp
  • G to T, chromosome 13 at 4,194,716 bp
  • T to C, chromosome 13 at 12,270,795 bp
  • A to G, chromosome 13 at 37,931,344 bp
  • A to T, chromosome 13 at 67,591,444 bp
  • T to C, chromosome 14 at 12,705,759 bp
  • A to T, chromosome 14 at 20,550,433 bp
  • A to T, chromosome 14 at 57,801,974 bp
  • A to T, chromosome 14 at 64,779,689 bp
  • A to T, chromosome 15 at 58,052,423 bp
  • A to T, chromosome 15 at 100,383,754 bp
  • C to T, chromosome 16 at 11,253,855 bp
  • C to A, chromosome 16 at 91,670,494 bp
  • T to C, chromosome 17 at 83,631,005 bp
  • G to T, chromosome 19 at 5,729,393 bp
  • T to C, chromosome 19 at 36,554,896 bp
  • A to G, chromosome 19 at 53,988,125 bp
  • A to G, chromosome Y at 1,245,614 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5408 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042977-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.