Strain Name:
C57BL/6J-MtgxR5418Btlr/Mmmh
Stock Number:
042986-MU
Citation ID:
RRID:MMRRC_042986-MU
Other Names:
R5418 (G1), C57BL/6J-MtgxR5418Btlr
Major Collection:

Gene Information

Pax6
Name: paired box 6
Synonyms: Pax-6, Dey, Dickie's small eye, 1500038E17Rik, AEY11, Gsfaey11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18508
HGNC: HGNC:8620
Homologene: 1212
Pkp4
Name: plakophilin 4
Synonyms: p0071, Armrp, 5031422I09Rik, 9430019K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227937
HGNC: HGNC:9026
Homologene: 2689
Slc4a7
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 7
Synonyms: E430014N10Rik, NBC3, NBCn1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218756
VEGA: 14
Homologene: 2680
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: DNA-PKcs, slip, DNAPDcs, XRCC7, DNA-PK, DOXNPH, dxnph
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Ncoa7
Name: nuclear receptor coactivator 7
Synonyms: 9030406N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 211329
VEGA: 10
Homologene: 65245
Mapk14
Name: mitogen-activated protein kinase 14
Synonyms: p38-alpha, p38, p38 MAP Kinase, Mxi2, CSBP2, Crk1, Csbp1, p38MAPK, p38a, p38 alpha, p38alpha, p38 MAP kinase alpha, p38 MAPK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 26416
HGNC: HGNC:6876
Homologene: 31777
Ap2b1
Name: adaptor-related protein complex 2, beta 1 subunit
Synonyms: 1300012O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71770
HGNC: HGNC:563
Homologene: 137384
Sema3f
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
Synonyms: Sema IV, Semak
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20350
Homologene: 20885
Senp6
Name: SUMO/sentrin specific peptidase 6
Synonyms: E130319N12Rik, 2810017C20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 215351
Homologene: 9196
Nbea
Name: neurobeachin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 26422
HGNC: HGNC:7648
Homologene: 69190
Mtmr12
Name: myotubularin related protein 12
Synonyms: C730015A02Rik, Pip3ap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 268783
Homologene: 10403
Tcf3
Name: transcription factor 3
Synonyms: ALF2, E2A, E47, E12, Pan2, Pan1, A1, Tcfe2a, bHLHb21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 21423
Homologene: 2408
Emc8
Name: ER membrane protein complex subunit 8
Synonyms: Noc4, Fam158b, Cox4nb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18117
HGNC: HGNC:7864
Homologene: 4424
Agps
Name: alkylglycerone phosphate synthase
Synonyms: ADAPS, 9930035G10Rik, bs2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228061
HGNC: HGNC:327
Homologene: 2716
Resf1
Name: retroelement silencing factor 1
Synonyms: GET, 2810474O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67246
Homologene: 19251
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F32S1, D15F32S1h, D7H15F37S1, rjs, jdf2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
Crlf2
Name: cytokine receptor-like factor 2
Synonyms: Ly114, Tslpr, Tpte2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 57914
Homologene: 49476
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Plxnb2
Name: plexin B2
Synonyms: Debt, 1110007H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 140570
HGNC: HGNC:9104
Homologene: 66630
Zfp960
Name: zinc finger protein 960
Synonyms: BC018101
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 449000
Homologene: 133884
Epha6
Name: Eph receptor A6
Synonyms: m-ehk2, Ehk2, Hek12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13840
Homologene: 56396
Erc2
Name: ELKS/RAB6-interacting/CAST family member 2
Synonyms: D14Ertd171e, ELKS2alpha, CAST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 238988
Homologene: 69188
Tpcn2
Name: two pore segment channel 2
Synonyms: D830047E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233979
Homologene: 16375
Piezo1
Name: piezo-type mechanosensitive ion channel component 1
Synonyms: Piezo1, Fam38a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234839
Homologene: 124356
Dennd1c
Name: DENN/MADD domain containing 1C
Synonyms: 4432409M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70785
VEGA: 17
Homologene: 11773
Col1a2
Name: collagen, type I, alpha 2
Synonyms: Col1a-2, Cola2, Cola-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12843
HGNC: HGNC:2198
Homologene: 69
Adamts4
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
Synonyms: aggrecanase-1, ADAM-TS4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240913
HGNC: HGNC:220
Homologene: 36169
Klb
Name: klotho beta
Synonyms: betaKlotho
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 83379
Homologene: 12820
Kcp
Name: kielin/chordin-like protein
Synonyms: LOC333088, KCP, Crim2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 333088
Homologene: 87817
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Add2
Name: adducin 2 (beta)
Synonyms: 2900072M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11519
HGNC: HGNC:244
Homologene: 1221
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: VLGR1, Mass1, Mgr1, Gpr98
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 110789
Homologene: 19815
Irs1
Name: insulin receptor substrate 1
Synonyms: IRS-1, G972R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16367
HGNC: HGNC:6125
Homologene: 4049
Taar1
Name: trace amine-associated receptor 1
Synonyms: Tar1, Trar1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 111174
VEGA: 10
Homologene: 24938
Hc
Name: hemolytic complement
Synonyms: C5a, C5, He, Hfib2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Scara5
Name: scavenger receptor class A, member 5
Synonyms: 4932433F15Rik, 4933425F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71145
Homologene: 12556
Vmn2r102
Name: vomeronasal 2, receptor 102
Synonyms: EG224572
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 224572
Homologene: 115024
Rbm11
Name: RNA binding motif protein 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224344
HGNC: HGNC:9897
Homologene: 16988
Fam234b
Name: family with sequence similarity 234, member B
Synonyms: 8430419L09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74525
Homologene: 12572
Bcl9l
Name: B cell CLL/lymphoma 9-like
Synonyms: DLNB11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80288
VEGA: 9
Homologene: 65615
Tmem184c
Name: transmembrane protein 184C
Synonyms: 8430433H16Rik, Tmem34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234463
Homologene: 32403
Disp2
Name: dispatched RND tramsporter family member 2
Synonyms: DispB, B230210L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214240
Homologene: 24916
4930568D16Rik
Name: RIKEN cDNA 4930568D16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75859
Homologene: 86865
Mmp1b
Name: matrix metallopeptidase 1b (interstitial collagenase)
Synonyms: Mcol-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 83996
HGNC: HGNC:7155
Homologene: 130791
Ankrd24
Name: ankyrin repeat domain 24
Synonyms: 5730519E19Rik, 4631433D01Rik, D10Bur2e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70615
Homologene: 49885
Mylk
Name: myosin, light polypeptide kinase
Synonyms: telokin, Mlck, MLCK210, MLCK108, 9530072E15Rik, A930019C19Rik, nmMlck
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 107589
HGNC: HGNC:7590
Homologene: 14202
Smarcal1
Name: SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
Synonyms: Mharp, 6030401P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 54380
Homologene: 8558
Hic1
Name: hypermethylated in cancer 1
Synonyms: HIC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15248
HGNC: HGNC:4909
Homologene: 4740
Fam120b
Name: family with sequence similarity 120, member B
Synonyms: CCPG, 4932442K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 67544
VEGA: 17
Homologene: 13033
Fcgbp
Name: Fc fragment of IgG binding protein
Synonyms: A430096B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 215384
Homologene: 68369
Prss40
Name: protease, serine 40
Synonyms: Tesp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21756
Homologene: 69043
Abcc1
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Synonyms: MRP, Mdrap, Mrp1, Abcc1b, Abcc1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17250
HGNC: HGNC:51
Homologene: 133779
Lrrc34
Name: leucine rich repeat containing 34
Synonyms: 1700007J06Rik, Spata34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 71827
Homologene: 27419
Sox7
Name: SRY (sex determining region Y)-box 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 20680
VEGA: 14
Homologene: 7949
Acoxl
Name: acyl-Coenzyme A oxidase-like
Synonyms: 1200014P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74121
Homologene: 75083
Klra6
Name: killer cell lectin-like receptor, subfamily A, member 6
Synonyms: Ly49F, Ly49f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16637
Homologene: 110821
Efcab11
Name: EF-hand calcium binding domain 11
Synonyms: 2610110A13Rik, 2610021K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 78767
VEGA: 12
Homologene: 44924
Prx
Name: periaxin
Synonyms: L-Periaxin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 19153
Homologene: 76542
Map3k9
Name: mitogen-activated protein kinase kinase kinase 9
Synonyms: Mlk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 338372
VEGA: 12
HGNC: HGNC:6861
Homologene: 76377
Alms1-ps1
Name: ALMS1, centrosome and basal body associated, pseudogene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 100043493
Frmd3
Name: FERM domain containing 3
Synonyms: EPB41L4O, P410, 4.1O, 9430066I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242506
Homologene: 16012
Zdhhc3
Name: zinc finger, DHHC domain containing 3
Synonyms: Zfp373, 1110020O22Rik, GODZ, 1810006O10Rik, 2210017C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 69035
Homologene: 9582
Etnk2
Name: ethanolamine kinase 2
Synonyms: 4933417N20Rik, Eki2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 214253
Homologene: 10072
Vmn1r232
Name: vomeronasal 1 receptor 232
Synonyms: V1re4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 171227
Homologene: 121611
Slc25a3
Name: solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
Synonyms: Phc, 5730556H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18674
Homologene: 37649
9530077C05Rik
Name: RIKEN cDNA 9530077C05 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68283
VEGA: 9
Homologene: 19280
Gm2058
Name: predicted gene 2058
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100039133
Acad8
Name: acyl-Coenzyme A dehydrogenase family, member 8
Synonyms: 2310016C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66948
HGNC: HGNC:87
Homologene: 8662
Fndc4
Name: fibronectin type III domain containing 4
Synonyms: 6330410H20Rik, FRCP1, 2810430J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 64339
Homologene: 49716
Ccr10
Name: chemokine (C-C motif) receptor 10
Synonyms: CCR10, GPR2, Cmkbr9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12777
HGNC: HGNC:4474
Homologene: 7271
Glrx2
Name: glutaredoxin 2 (thioltransferase)
Synonyms: 1700010P22Rik, Grx2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 69367
Homologene: 41098
Olfr1252
Name: olfactory receptor 1252
Synonyms: GA_x6K02T2Q125-51162884-51161940, MOR231-22_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 404331
Homologene: 128094
Cflar
Name: CASP8 and FADD-like apoptosis regulator
Synonyms: Casper, A430105C05Rik, Flip, c-Flip, 2310024N18Rik, Cash
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12633
HGNC: HGNC:1876
Homologene: 7652
Dnase1l1
Name: deoxyribonuclease 1-like 1
Synonyms: G4.8, Dnl1ll, 2310005K03Rik, Dnase1ll
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 69537
HGNC: HGNC:2957
Homologene: 4896
Bin2
Name: bridging integrator 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 668218
HGNC: HGNC:1053
Homologene: 22965
Gm27953
Name: predicted gene, 27953
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Igkv4-92
Name: immunoglobulin kappa variable 4-92
Synonyms: LOC384410, IgVk ay4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 384410
Traj21
Name: T cell receptor alpha joining 21
Synonyms: Gm16815
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100124368
Gm21898
Name: predicted gene, 21898
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
Homologene: 86944
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 34,560,759 bp
  • A to T, chromosome 1 at 58,752,651 bp
  • C to T, chromosome 1 at 72,598,909 bp
  • G to A, chromosome 1 at 82,288,770 bp
  • T to C, chromosome 1 at 133,373,257 bp
  • C to A, chromosome 1 at 143,739,708 bp
  • T to A, chromosome 1 at 171,252,574 bp
  • C to T, chromosome 2 at 35,008,183 bp
  • A to G, chromosome 2 at 35,354,726 bp
  • A to G, chromosome 2 at 36,087,366 bp
  • T to C, chromosome 2 at 59,310,162 bp
  • A to G, chromosome 2 at 75,858,904 bp
  • T to C, chromosome 2 at 89,721,999 bp
  • A to T, chromosome 2 at 105,691,565 bp
  • A to C, chromosome 2 at 118,787,232 bp
  • T to A, chromosome 2 at 127,877,802 bp
  • G to A, chromosome 3 at 30,642,774 bp
  • A to T, chromosome 3 at 55,645,989 bp
  • G to A, chromosome 4 at 74,161,698 bp
  • A to T, chromosome 5 at 31,294,634 bp
  • A to G, chromosome 5 at 65,383,470 bp
  • A to G, chromosome 5 at 109,557,033 bp
  • A to G, chromosome 6 at 4,516,931 bp
  • A to T, chromosome 6 at 29,504,284 bp
  • A to T, chromosome 6 at 68,755,580 bp
  • G to A, chromosome 6 at 85,755,602 bp
  • A to G, chromosome 6 at 86,110,912 bp
  • T to A, chromosome 6 at 130,013,430 bp
  • A to G, chromosome 6 at 135,226,968 bp
  • T to C, chromosome 6 at 149,326,136 bp
  • T to A, chromosome 7 at 27,517,274 bp
  • G to A, chromosome 7 at 28,085,313 bp
  • T to G, chromosome 7 at 39,588,934 bp
  • T to C, chromosome 7 at 56,137,565 bp
  • C to T, chromosome 7 at 145,278,781 bp
  • A to G, chromosome 8 at 77,597,820 bp
  • G to A, chromosome 8 at 120,658,603 bp
  • A to G, chromosome 8 at 122,486,780 bp
  • T to C, chromosome 9 at 7,384,897 bp
  • G to T, chromosome 9 at 22,431,770 bp
  • A to T, chromosome 9 at 26,985,557 bp
  • A to G, chromosome 9 at 44,505,436 bp
  • A to G, chromosome 9 at 54,374,651 bp
  • G to A, chromosome 9 at 80,121,869 bp
  • A to G, chromosome 9 at 107,692,621 bp
  • A to G, chromosome 9 at 123,080,391 bp
  • T to C, chromosome 10 at 23,921,316 bp
  • A to G, chromosome 10 at 30,648,039 bp
  • A to G, chromosome 10 at 80,427,683 bp
  • T to A, chromosome 10 at 81,644,942 bp
  • T to C, chromosome 10 at 91,119,536 bp
  • A to G, chromosome 11 at 75,166,599 bp
  • A to G, chromosome 11 at 83,316,445 bp
  • C to T, chromosome 11 at 101,174,078 bp
  • A to G, chromosome 11 at 107,111,294 bp
  • C to A, chromosome 11 at 118,094,984 bp
  • T to A, chromosome 12 at 81,743,817 bp
  • A to G, chromosome 12 at 99,855,618 bp
  • T to A, chromosome 13 at 81,419,308 bp
  • T to A, chromosome 14 at 14,760,280 bp
  • A to G, chromosome 14 at 27,966,510 bp
  • A to G, chromosome 14 at 54,198,818 bp
  • C to T, chromosome 14 at 63,947,947 bp
  • CG to C, chromosome 14 at 65,759,662 bp
  • T to C, chromosome 15 at 12,269,959 bp
  • A to G, chromosome 15 at 89,166,491 bp
  • T to C, chromosome 15 at 100,649,146 bp
  • T to C, chromosome 16 at 14,461,132 bp
  • T to G, chromosome 16 at 15,795,097 bp
  • T to C, chromosome 16 at 34,912,230 bp
  • C to A, chromosome 16 at 60,424,835 bp
  • A to C, chromosome 16 at 75,596,535 bp
  • C to T, chromosome 17 at 15,401,799 bp
  • T to A, chromosome 17 at 17,087,543 bp
  • C to T, chromosome 17 at 19,694,153 bp
  • T to A, chromosome 17 at 20,914,116 bp
  • T to C, chromosome 17 at 28,741,843 bp
  • CCGCCCCTCGCTGACAGC to CC, chromosome 17 at 57,066,755 bp
  • C to T, chromosome X at 74,277,038 bp
  • T to C, chromosome Y at 36,025,731 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5418 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
042986-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.