Strain Name:
C57BL/6J-MtgxR5435Btlr/Mmmh
Stock Number:
043000-MU
Citation ID:
RRID:MMRRC_043000-MU
Other Names:
R5435 (G1), C57BL/6J-MtgxR5435Btlr
Major Collection:

Gene Information

Col2a1
Name: collagen, type II, alpha 1
Synonyms: Del1, Lpk, M100856, Col2, Rgsc856, Col2a, Col2a-1, M100413, Rgsc413
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12824
HGNC: HGNC:2200
Homologene: 55607
Prkar2a
Name: protein kinase, cAMP dependent regulatory, type II alpha
Synonyms: 1110061A24Rik, RII(alpha)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 19087
HGNC: HGNC:9391
Homologene: 3064
Myh9
Name: myosin, heavy polypeptide 9, non-muscle
Synonyms: NMHC II-A, Myhn1, E030044M24Rik, Fltn, D0Jmb2, Myhn-1, myosin IIA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 17886
HGNC: HGNC:7579
Homologene: 129835
Setd5
Name: SET domain containing 5
Synonyms: 2900045N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 72895
Homologene: 12485
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Herc3
Name: hect domain and RLD 3
Synonyms: 5730409F18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 73998
HGNC: HGNC:4876
Homologene: 57095
Wee1
Name: WEE 1 homolog 1 (S. pombe)
Synonyms: Wee1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22390
Homologene: 31152
Adam23
Name: a disintegrin and metallopeptidase domain 23
Synonyms: MDC3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 23792
HGNC: HGNC:202
Homologene: 2826
Aff1
Name: AF4/FMR2 family, member 1
Synonyms: Mllt2h, Af4, 9630032B01Rik, Rob
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17355
HGNC: HGNC:7135
Homologene: 4340
Relch
Name: RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
Synonyms: 2310035C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227446
Homologene: 10834
Rbbp5
Name: retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit
Synonyms: 4933411J24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 213464
HGNC: HGNC:9888
Homologene: 3709
Ccar2
Name: cell cycle activator and apoptosis regulator 2
Synonyms: Dbc1, 2610301G19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219158
VEGA: 14
Homologene: 10910
Mettl25
Name: methyltransferase like 25
Synonyms: BC067068
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216292
Homologene: 32774
Stag1
Name: stromal antigen 1
Synonyms: SA-1, Scc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20842
Homologene: 21191
Gmnn
Name: geminin
Synonyms: Gem
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 57441
Homologene: 9292
Ap1g1
Name: adaptor protein complex AP-1, gamma 1 subunit
Synonyms: gamma-adaptin, D8Ertd374e, Adtg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 11765
HGNC: HGNC:555
Homologene: 47995
Ift74
Name: intraflagellar transport 74
Synonyms: 1700029H06Rik, Cmg1, b2b796Clo, Ccdc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 67694
Homologene: 11831
Abca17
Name: ATP-binding cassette, sub-family A (ABC1), member 17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 381072
Homologene: 86807
Kank1
Name: KN motif and ankyrin repeat domains 1
Synonyms: Ankrd15, D330024H06Rik, A930031B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107351
Homologene: 17706
Rasa3
Name: RAS p21 protein activator 3
Synonyms: R-Ras gap, GAPIII activator 3, hlb381, GAPIII, Ras GTPase-activating protein III, scat
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 19414
Homologene: 7217
Aph1c
Name: aph1 homolog C, gamma secretase subunit
Synonyms: 0610008A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 68318
Homologene: 134745
Adgra3
Name: adhesion G protein-coupled receptor A3
Synonyms: Gpr125, 3830613O22Rik, Tem5-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 70693
Homologene: 19235
Mpdz
Name: multiple PDZ domain protein
Synonyms: B930003D11Rik, MUPP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 17475
HGNC: HGNC:7208
Homologene: 2841
Hnrnpul2
Name: heterogeneous nuclear ribonucleoprotein U-like 2
Synonyms: 1110031M08Rik, Hnrpul2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 68693
VEGA: 19
Homologene: 28583
Tubgcp2
Name: tubulin, gamma complex associated protein 2
Synonyms: 1700022B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 74237
Homologene: 55980
Inpp5f
Name: inositol polyphosphate-5-phosphatase F
Synonyms: SAC2, 5830435P03Rik, cI-27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101490
Homologene: 8962
Peak1
Name: pseudopodium-enriched atypical kinase 1
Synonyms: 1110049L02Rik, C230081A13Rik, NKF3 kinase family member
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244895
Homologene: 18259
Tbc1d32
Name: TBC1 domain family, member 32
Synonyms: Bromi, D630037F22Rik, b2b2284Clo, C6orf170
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 544696
VEGA: 10
Homologene: 51889
Col4a4
Name: collagen, type IV, alpha 4
Synonyms: E130010M05Rik, [a]4(IV)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12829
HGNC: HGNC:2206
Homologene: 20071
Dnajc6
Name: DnaJ heat shock protein family (Hsp40) member C6
Synonyms: 2810027M23Rik, auxilin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 72685
Homologene: 8865
Anxa9
Name: annexin A9
Synonyms: 2310069F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71790
HGNC: HGNC:547
Homologene: 2643
Scn1a
Name: sodium channel, voltage-gated, type I, alpha
Synonyms: Nav1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20265
Homologene: 21375
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Col12a1
Name: collagen, type XII, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12816
HGNC: HGNC:2188
Homologene: 3217
Pik3c2g
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18705
HGNC: HGNC:8973
Homologene: 3362
Ccdc116
Name: coiled-coil domain containing 116
Synonyms: 4930432J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 76872
Homologene: 51873
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 545030
Homologene: 83473
Gls2
Name: glutaminase 2 (liver, mitochondrial)
Synonyms: A330074B06Rik, Lga
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216456
Homologene: 40861
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22635
Homologene: 124417
Trank1
Name: tetratricopeptide repeat and ankyrin repeat containing 1
Synonyms: A230061D21Rik, C030048J01Rik, Lba1, LOC235639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 320429
Homologene: 45845
Guf1
Name: GUF1 homolog, GTPase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231279
Homologene: 6505
Kcnma1
Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Synonyms: 5730414M22Rik, BKCa, Slo, BK channel alpha subunit, MaxiK, Slo1, mSlo1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16531
HGNC: HGNC:6284
Homologene: 1693
Bdh1
Name: 3-hydroxybutyrate dehydrogenase, type 1
Synonyms: 2310032J20Rik, Bdh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 71911
HGNC: HGNC:1027
Homologene: 20860
B3galnt2
Name: UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2
Synonyms: D230016N13Rik, A930105D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 97884
VEGA: 13
Homologene: 17595
Zfp735
Name: zinc finger protein 735
Synonyms: 1700012C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76390
Homologene: 88945
Neto1
Name: neuropilin (NRP) and tolloid (TLL)-like 1
Synonyms: C130005O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 246317
VEGA: 18
Homologene: 16367
Olfr992
Name: olfactory receptor 992
Synonyms: MOR203-1, GA_x6K02T2Q125-46877170-46876241
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258865
Homologene: 121517
Psg26
Name: pregnancy-specific glycoprotein 26
Synonyms: cea14, EG574429
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 574429
Homologene: 110989
Acsf3
Name: acyl-CoA synthetase family member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 257633
Homologene: 14958
3425401B19Rik
Name: RIKEN cDNA 3425401B19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 100504518
VEGA: 14
Homologene: 54908
Fkbpl
Name: FK506 binding protein-like
Synonyms: WAF-1/CIP1 stabilizing protein 39, DIR1, Ppiase-X, NG7, WISp39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 56299
Homologene: 10529
Hmgn1
Name: high mobility group nucleosomal binding domain 1
Synonyms: Hmg14, HMG-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 15312
HGNC: HGNC:4984
Homologene: 3643
Zfyve16
Name: zinc finger, FYVE domain containing 16
Synonyms: B130024H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218441
Homologene: 8826
Tchh
Name: trichohyalin
Synonyms: AHF, Thh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99681
Homologene: 136273
Foxf1
Name: forkhead box F1
Synonyms: Freac-1, Hfh8, Foxf1, HFH-8, Foxf1a, FREAC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 15227
HGNC: HGNC:3809
Homologene: 1114
Wdr35
Name: WD repeat domain 35
Synonyms: 4930459M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 74682
Homologene: 10814
Acsbg1
Name: acyl-CoA synthetase bubblegum family member 1
Synonyms: Bgm, E230019G03Rik, Lpd, BG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 94180
Homologene: 9044
Ddx19b
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b
Synonyms: 2810457M08Rik, 4921519L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234733
HGNC: HGNC:2742
Homologene: 56032
H2-Q6
Name: histocompatibility 2, Q region locus 6
Synonyms: H-2Q6, Qa-6, 0610037M15Rik, Qa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 110557
HGNC: HGNC:4931
Homologene: 128352
Rps10-ps1
Name: ribosomal protein S10, pseudogene 1
Synonyms: Gm9180
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 668457
Pih1d1
Name: PIH1 domain containing 1
Synonyms: 4933413A04Rik, 1110061L23Rik, Nop17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68845
Homologene: 9914
Nol7
Name: nucleolar protein 7
Synonyms: RARG-1, NOP27, 2210008F15Rik, 5730556I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 70078
VEGA: 13
Homologene: 49451
R3hdm4
Name: R3H domain containing 4
Synonyms: C030046I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 109284
VEGA: 10
Homologene: 16343
Fbxo4
Name: F-box protein 4
Synonyms: 1700096C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 106052
Homologene: 8134
Ccdc107
Name: coiled-coil domain containing 107
Synonyms: 1110032O22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 622404
Homologene: 52163
Ccl12
Name: chemokine (C-C motif) ligand 12
Synonyms: Scya12, MCP-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20293
Homologene: 2245
Pcdha8
Name: protocadherin alpha 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 353235
HGNC: HGNC:8675
Homologene: 129614
Ighv5-4
Name: immunoglobulin heavy variable 5-4
Synonyms: Gm16971
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 777688
Gm13599
Name: predicted gene 13599
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 102639471
Gm9967
Name: predicted gene 9967
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 63,546,453 bp
  • T to A, chromosome 1 at 82,454,007 bp
  • T to A, chromosome 1 at 105,741,250 bp
  • T to A, chromosome 1 at 132,494,275 bp
  • T to A, chromosome 2 at 66,273,534 bp
  • T to A, chromosome 2 at 67,396,152 bp
  • A to T, chromosome 2 at 76,914,358 bp
  • T to A, chromosome 2 at 85,400,470 bp
  • C to A, chromosome 3 at 93,443,672 bp
  • T to C, chromosome 3 at 95,297,250 bp
  • C to A, chromosome 3 at 95,622,458 bp
  • A to T, chromosome 4 at 43,493,519 bp
  • A to G, chromosome 4 at 81,283,487 bp
  • A to G, chromosome 4 at 94,686,813 bp
  • A to T, chromosome 4 at 101,606,610 bp
  • G to A, chromosome 5 at 49,990,126 bp
  • A to T, chromosome 5 at 69,563,169 bp
  • G to A, chromosome 5 at 103,754,332 bp
  • T to A, chromosome 5 at 137,403,762 bp
  • T to A, chromosome 6 at 58,855,806 bp
  • T to A, chromosome 6 at 73,060,138 bp
  • G to A, chromosome 6 at 113,151,221 bp
  • T to G, chromosome 6 at 139,715,855 bp
  • A to G, chromosome 7 at 18,478,473 bp
  • T to A, chromosome 7 at 45,156,272 bp
  • TCCCC to TCCC, chromosome 7 at 110,124,569 bp
  • A to G, chromosome 7 at 126,775,788 bp
  • T to A, chromosome 7 at 128,675,324 bp
  • G to A, chromosome 7 at 139,996,072 bp
  • T to C, chromosome 8 at 13,631,811 bp
  • T to A, chromosome 8 at 109,838,920 bp
  • T to C, chromosome 8 at 111,008,826 bp
  • G to A, chromosome 8 at 121,084,492 bp
  • T to A, chromosome 8 at 122,780,281 bp
  • G to T, chromosome 9 at 54,615,869 bp
  • A to G, chromosome 9 at 56,206,486 bp
  • A to T, chromosome 9 at 66,834,501 bp
  • A to G, chromosome 9 at 79,707,901 bp
  • A to G, chromosome 9 at 100,953,550 bp
  • A to G, chromosome 9 at 108,740,483 bp
  • A to G, chromosome 9 at 111,391,890 bp
  • C to A, chromosome 10 at 56,040,150 bp
  • C to T, chromosome 10 at 79,912,458 bp
  • A to G, chromosome 10 at 105,779,586 bp
  • G to A, chromosome 10 at 128,195,126 bp
  • T to A, chromosome 11 at 73,712,113 bp
  • T to C, chromosome 11 at 82,103,175 bp
  • A to G, chromosome 12 at 8,989,951 bp
  • A to G, chromosome 12 at 113,597,663 bp
  • A to T, chromosome 13 at 13,777,064 bp
  • A to G, chromosome 13 at 13,996,990 bp
  • A to G, chromosome 13 at 24,752,101 bp
  • C to A, chromosome 13 at 43,401,372 bp
  • A to G, chromosome 13 at 92,508,237 bp
  • A to T, chromosome 14 at 23,528,404 bp
  • A to G, chromosome 14 at 32,661,456 bp
  • A to G, chromosome 14 at 33,020,311 bp
  • A to G, chromosome 14 at 70,139,327 bp
  • C to T, chromosome 15 at 3,965,792 bp
  • C to T, chromosome 15 at 77,769,609 bp
  • T to C, chromosome 15 at 98,000,510 bp
  • G to T, chromosome 16 at 17,142,762 bp
  • C to T, chromosome 16 at 31,456,657 bp
  • A to T, chromosome 16 at 96,122,330 bp
  • C to T, chromosome 17 at 24,267,614 bp
  • G to A, chromosome 17 at 34,645,329 bp
  • A to G, chromosome 17 at 35,425,685 bp
  • A to G, chromosome 18 at 36,993,599 bp
  • A to T, chromosome 18 at 86,398,263 bp
  • T to G, chromosome 19 at 8,820,318 bp
  • T to G, chromosome 19 at 25,411,143 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5435 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043000-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.