Strain Name:
C57BL/6J-MtgxR5479Btlr/Mmmh
Stock Number:
043040-MU
Citation ID:
RRID:MMRRC_043040-MU
Other Names:
R5479 (G1), C57BL/6J-MtgxR5479Btlr
Major Collection:

Gene Information

Ptprz1
Name: protein tyrosine phosphatase, receptor type Z, polypeptide 1
Synonyms: DSD-1-PG, phosphacan, PTPzeta, PTPbeta, Rptpbeta, Ptpz, Ptprz, RPTPz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Mbd5
Name: methyl-CpG binding domain protein 5
Synonyms: 9430004D19Rik, C030040A15Rik, OTTMUSG00000012483
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 109241
Homologene: 81861
Nrg1
Name: neuregulin 1
Synonyms: HGL, HRG, Hgl, SMDF, GGF, ARIA, heregulin, D230005F13Rik, HRGalpha, 6030402G23Rik, GGFII, NDF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 211323
HGNC: HGNC:7997
Homologene: 138451
Ncam2
Name: neural cell adhesion molecule 2
Synonyms: RNCAM, R4B12 antigen, Ncam-2, Ocam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17968
HGNC: HGNC:7657
Homologene: 3336
Gnai2
Name: guanine nucleotide binding protein (G protein), alpha inhibiting 2
Synonyms: Gia, Gnai-2, Galphai2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 14678
HGNC: HGNC:4385
Homologene: 55539
Dgka
Name: diacylglycerol kinase, alpha
Synonyms: Dagk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 13139
VEGA: 10
HGNC: HGNC:2849
Homologene: 1028
Ggnbp2
Name: gametogenetin binding protein 2
Synonyms: DIF-3, Zfp403, D330017P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217039
Homologene: 11750
Pard3
Name: par-3 family cell polarity regulator
Synonyms: ASIP, D8Ertd580e, PAR-3, Par3, Pard3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 93742
Homologene: 10489
Apbb2
Name: amyloid beta (A4) precursor protein-binding, family B, member 2
Synonyms: TR2L, Rirl1, 2310007D03Rik, Zfra, FE65L1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11787
HGNC: HGNC:582
Homologene: 32079
Usp25
Name: ubiquitin specific peptidase 25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 30940
VEGA: 16
Homologene: 8374
Cep57
Name: centrosomal protein 57
Synonyms: 4931428M20Rik, 4921510P06Rik, Tsp57, 3110002L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74360
Homologene: 8790
Elp1
Name: elongator complex protein 1
Synonyms: 3110040G09Rik, C78473, IKAP, Ikbkap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230233
HGNC: HGNC:5959
Homologene: 2699
Parp4
Name: poly (ADP-ribose) polymerase family, member 4
Synonyms: VPARP, VAULT3, p193, PH5P, E230037B21Rik, Adprtl1, C030027K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 328417
HGNC: HGNC:271
Homologene: 124423
Nfs1
Name: nitrogen fixation gene 1 (S. cerevisiae)
Synonyms: m-Nfs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18041
Homologene: 5463
Chd8
Name: chromodomain helicase DNA binding protein 8
Synonyms: 5830451P18Rik, Duplin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 67772
Homologene: 72405
Eya3
Name: EYA transcriptional coactivator and phosphatase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14050
HGNC: HGNC:3521
Homologene: 1508
Sptb
Name: spectrin beta, erythrocytic
Synonyms: Spnb-1, spectrin R, D330027P03Rik, LOC383567, brain erythroid spectrin (235E), Spnb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20741
Homologene: 295
Acsl5
Name: acyl-CoA synthetase long-chain family member 5
Synonyms: 1700030F05Rik, Facl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 433256
VEGA: 19
Homologene: 69208
Ppp3cb
Name: protein phosphatase 3, catalytic subunit, beta isoform
Synonyms: PP2BA beta, Calnb, CnAbeta, 1110063J16Rik, Cnab
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19056
HGNC: HGNC:9315
Homologene: 56429
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Zfp148
Name: zinc finger protein 148
Synonyms: beta enolase repressor factor 1, BERF-1, BFCOL1, 2210405J08Rik, ZBP-89
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 22661
VEGA: 16
Homologene: 8003
Exosc10
Name: exosome component 10
Synonyms: PM/Scl-100, PM-Scl, RRP6, p4, p3, p2, Pmscl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 50912
HGNC: HGNC:9138
Homologene: 31105
Pnpla7
Name: patatin-like phospholipase domain containing 7
Synonyms: E430013P11Rik, NRE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241274
Homologene: 62431
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269700
Homologene: 28297
Plxna2
Name: plexin A2
Synonyms: OCT, Plxn2, 2810428A13Rik, PlexA2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18845
HGNC: HGNC:9100
Homologene: 56427
Myh13
Name: myosin, heavy polypeptide 13, skeletal muscle
Synonyms: extraocular myosin, EO Myosin, MyHC-eo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 544791
HGNC: HGNC:7571
Homologene: 55780
Pilra
Name: paired immunoglobin-like type 2 receptor alpha
Synonyms: FDF03
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231805
Homologene: 8387
Maz
Name: MYC-associated zinc finger protein (purine-binding transcription factor)
Synonyms: Pur-1, PUR1, SAF-2, SAF-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17188
HGNC: HGNC:6914
Homologene: 106451
Apbb1
Name: amyloid beta (A4) precursor protein-binding, family B, member 1
Synonyms: Fe65, Rir
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11785
HGNC: HGNC:581
Homologene: 898
Grik1
Name: glutamate receptor, ionotropic, kainate 1
Synonyms: Glur-5, Glur5, D16Ium24, A830007B11Rik, D16Ium24e, Glurbeta1, GluK5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 14805
HGNC: HGNC:4579
Homologene: 68992
Mdga2
Name: MAM domain containing glycosylphosphatidylinositol anchor 2
Synonyms: Mdga2, 9330209L04Rik, 6720489L24Rik, Mamdc1, Adp, Tg(Prnp-PFN1*G118V)838Kiaei
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 320772
Homologene: 45659
Ppfibp1
Name: PTPRF interacting protein, binding protein 1 (liprin beta 1)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67533
HGNC: HGNC:9249
Homologene: 2685
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: LOC227058, Dnahc7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227058
Homologene: 41287
Gpx5
Name: glutathione peroxidase 5
Synonyms: Arep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14780
HGNC: HGNC:4557
Homologene: 1155
Agbl4
Name: ATP/GTP binding protein-like 4
Synonyms: 4930578N11Rik, 4931433A01Rik, Ccp6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 78933
Homologene: 84880
Klra9
Name: killer cell lectin-like receptor subfamily A, member 9
Synonyms: Ly49I, LY49I1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16640
Homologene: 110821
Piwil4
Name: piwi-like RNA-mediated gene silencing 4
Synonyms: 9230101H05Rik, Miwi2, MIWI2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 330890
Homologene: 45122
Mios
Name: meiosis regulator for oocyte development
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 252875
Homologene: 10371
Ctrl
Name: chymotrypsin-like
Synonyms: 1810004D15Rik, Ctra1, 0910001G08Rik, Ctra-1, chymopasin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 109660
HGNC: HGNC:2524
Homologene: 37549
Nrbf2
Name: nuclear receptor binding factor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 641340
Homologene: 41473
Adad2
Name: adenosine deaminase domain containing 2
Synonyms: 4930403J07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 75773
Homologene: 16392
Cyp4v3
Name: cytochrome P450, family 4, subfamily v, polypeptide 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102294
Homologene: 133054
Ftcd
Name: formiminotransferase cyclodeaminase
Synonyms: glutamate formiminotransferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14317
HGNC: HGNC:3974
Homologene: 4848
Olfr1208
Name: olfactory receptor 1208
Synonyms: GA_x6K02T2Q125-50372411-50371485, MOR225-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258774
Homologene: 74190
Onecut3
Name: one cut domain, family member 3
Synonyms: OC-3, Oc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 246086
Homologene: 82258
Gm23156
Name: predicted gene, 23156
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Frs3os
Name: fibroblast growth factor receptor substrate 3, opposite strand
Synonyms: Gm14873
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 100126242
B020004C17Rik
Name: RIKEN cDNA B020004C17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 432860
VEGA: 14
Homologene: 128423
Gm10251
Name: predicted gene 10251
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 46,223,105 bp
  • G to A, chromosome 1 at 194,793,873 bp
  • T to C, chromosome 2 at 25,019,441 bp
  • T to C, chromosome 2 at 49,272,905 bp
  • T to C, chromosome 2 at 88,896,691 bp
  • G to A, chromosome 2 at 156,128,502 bp
  • A to G, chromosome 4 at 56,757,186 bp
  • A to G, chromosome 4 at 110,955,672 bp
  • A to G, chromosome 4 at 132,672,933 bp
  • A to G, chromosome 4 at 148,573,348 bp
  • A to G, chromosome 5 at 66,313,475 bp
  • A to T, chromosome 5 at 121,306,948 bp
  • A to G, chromosome 5 at 137,836,056 bp
  • C to T, chromosome 6 at 8,215,314 bp
  • C to T, chromosome 6 at 23,001,666 bp
  • T to C, chromosome 6 at 130,179,112 bp
  • T to A, chromosome 6 at 147,030,150 bp
  • A to T, chromosome 7 at 105,565,025 bp
  • A to T, chromosome 7 at 127,025,688 bp
  • T to C, chromosome 8 at 31,818,377 bp
  • A to G, chromosome 8 at 45,036,875 bp
  • T to A, chromosome 8 at 45,310,206 bp
  • A to G, chromosome 8 at 105,933,040 bp
  • C to A, chromosome 8 at 119,614,915 bp
  • G to A, chromosome 8 at 127,370,355 bp
  • T to C, chromosome 9 at 13,813,494 bp
  • T to C, chromosome 9 at 14,705,041 bp
  • T to G, chromosome 9 at 107,635,166 bp
  • T to C, chromosome 9 at 108,844,544 bp
  • A to G, chromosome 10 at 67,285,091 bp
  • A to T, chromosome 10 at 76,578,016 bp
  • T to A, chromosome 10 at 80,514,022 bp
  • T to A, chromosome 10 at 128,729,672 bp
  • G to A, chromosome 11 at 67,348,822 bp
  • T to C, chromosome 11 at 84,854,343 bp
  • C to T, chromosome 12 at 66,655,176 bp
  • T to C, chromosome 12 at 76,599,851 bp
  • T to C, chromosome 13 at 21,292,635 bp
  • C to T, chromosome 14 at 6,675,781 bp
  • A to T, chromosome 14 at 20,503,281 bp
  • C to T, chromosome 14 at 52,215,195 bp
  • T to C, chromosome 14 at 56,624,095 bp
  • T to C, chromosome 14 at 57,016,542 bp
  • C to A, chromosome 16 at 33,497,219 bp
  • T to C, chromosome 16 at 77,107,913 bp
  • C to T, chromosome 16 at 81,434,878 bp
  • C to A, chromosome 16 at 87,936,026 bp
  • A to G, chromosome 17 at 47,701,710 bp
  • G to T, chromosome 19 at 55,280,462 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5479 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043040-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.