Strain Name:
C57BL/6J-MtgxR5482Btlr/Mmmh
Stock Number:
043043-MU
Citation ID:
RRID:MMRRC_043043-MU
Other Names:
R5482 (G1), C57BL/6J-MtgxR5482Btlr
Major Collection:

Gene Information

Trmt9b
Name: tRNA methyltransferase 9B
Synonyms: 6430573F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 319582
Homologene: 35306
Wnt5b
Name: wingless-type MMTV integration site family, member 5B
Synonyms: Wnt-5b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 22419
Homologene: 22530
Lrrn3
Name: leucine rich repeat protein 3, neuronal
Synonyms: NLRR-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 16981
VEGA: 12
Homologene: 36315
Adgrl3
Name: adhesion G protein-coupled receptor L3
Synonyms: D130075K09Rik, 5430402I23Rik, LEC3, lectomedin 3, Lphn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 319387
Homologene: 22878
Fam133b
Name: family with sequence similarity 133, member B
Synonyms: 5830415L20Rik, 2900022K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 68152
Homologene: 85443
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, D630005A10Rik, A430040A19Rik, Bruce, A430032G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12211
Homologene: 7248
Rufy3
Name: RUN and FYVE domain containing 3
Synonyms: Rpipx, 6330416M07Rik, D5Bwg0860e, 2810428M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 52822
Homologene: 87809
Trappc12
Name: trafficking protein particle complex 12
Synonyms: CGI-87, D930014A20Rik, Ttc15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217449
VEGA: 12
Homologene: 34805
Pip5k1c
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma
Synonyms: PIP5KIgamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 18717
HGNC: HGNC:8996
Homologene: 69032
Acy1
Name: aminoacylase 1
Synonyms: 1110014J22Rik, Acy-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 109652
HGNC: HGNC:177
Homologene: 110440
Sun2
Name: Sad1 and UNC84 domain containing 2
Synonyms: Unc84b, B230369L08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223697
Homologene: 9113
Akap5
Name: A kinase (PRKA) anchor protein 5
Synonyms: 3526401B18Rik, LOC238276, AKAP150
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238276
HGNC: HGNC:375
Homologene: 15854
Acvr1
Name: activin A receptor, type 1
Synonyms: Alk-2, Acvr1a, ALK2, Acvr, Alk8, ActRIA, D330013D15Rik, Acvrlk2, ActR-I, Tsk7L, SKR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 11477
HGNC: HGNC:171
Homologene: 7
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Ralbp1
Name: ralA binding protein 1
Synonyms: RLIP76, Rip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 19765
VEGA: 17
HGNC: HGNC:9841
Homologene: 4940
Wdr36
Name: WD repeat domain 36
Synonyms: 5730444A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225348
VEGA: 18
Homologene: 6536
Bik
Name: BCL2-interacting killer
Synonyms: Biklk, Nbk, Blk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12124
VEGA: 15
HGNC: HGNC:1051
Homologene: 924
Usp2
Name: ubiquitin specific peptidase 2
Synonyms: B930035K21Rik, ubp41
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 53376
Homologene: 3098
Arap3
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Synonyms: E030006K04Rik, Centd3, DRAG1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 106952
VEGA: 18
Homologene: 11199
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
Homologene: 110349
Aplp1
Name: amyloid beta (A4) precursor-like protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11803
HGNC: HGNC:597
Homologene: 68447
Dock3
Name: dedicator of cyto-kinesis 3
Synonyms: Moca, PBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 208869
HGNC: HGNC:2989
Homologene: 21030
Abca15
Name: ATP-binding cassette, sub-family A (ABC1), member 15
Synonyms: 4930500I12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 320631
Homologene: 87255
Vmn2r26
Name: vomeronasal 2, receptor 26
Synonyms: V2r1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 56552
Homologene: 135915
Clstn3
Name: calsyntenin 3
Synonyms: CSTN3, alcadein-beta, Cst-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232370
Homologene: 22836
Syna
Name: syncytin a
Synonyms: syncytin-A, Gm52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 214292
Homologene: 86751
Skint2
Name: selection and upkeep of intraepithelial T cells 2
Synonyms: B7S3, OTTMUSG00000008540
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 329919
Homologene: 136741
Btn2a2
Name: butyrophilin, subfamily 2, member A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 238555
HGNC: HGNC:1137
Homologene: 56012
Hecw2
Name: HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Synonyms: Nedl2, D030049F17Rik, A730039N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329152
Homologene: 66192
Pign
Name: phosphatidylinositol glycan anchor biosynthesis, class N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 27392
HGNC: HGNC:8967
Homologene: 6330
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 628870
Homologene: 46008
Ppp1r18
Name: protein phosphatase 1, regulatory subunit 18
Synonyms: 2310014H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 76448
Homologene: 19512
Lrrk1
Name: leucine-rich repeat kinase 1
Synonyms: D130026O16Rik, C230002E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233328
Homologene: 23464
Tgfbr3
Name: transforming growth factor, beta receptor III
Synonyms: TBRIII, 1110036H20Rik, betaglycan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 21814
Homologene: 2436
Cfap57
Name: cilia and flagella associated protein 57
Synonyms: LOC384050, C130004B06Rik, 1110020C03Rik, Wdr65
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 68625
Homologene: 51350
Gm10722
Name: predicted gene 10722
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
Gmcl1
Name: germ cell-less, spermatogenesis associated 1
Synonyms: mglc-1, Gcl, 2810049L19Rik, Btbd13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 23885
Homologene: 8021
Olfr1448
Name: olfactory receptor 1448
Synonyms: GA_x6K02T2RE5P-3249780-3248836, MOR202-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258696
Homologene: 64904
Acap3
Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
Synonyms: Centb5, Kiaa1716-hp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 140500
Homologene: 23708
Myo18b
Name: myosin XVIIIb
Synonyms: 4933411E19Rik, 4932408L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74376
Homologene: 53435
Ttll11
Name: tubulin tyrosine ligase-like family, member 11
Synonyms: 4933424A20Rik, D2Ertd624e, 4932702F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 74410
Homologene: 77534
Ripply2
Name: ripply transcriptional repressor 2
Synonyms: LOC382089, C030002E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382089
Homologene: 19960
Nt5dc3
Name: 5'-nucleotidase domain containing 3
Synonyms: C630002B14Rik, Gnn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103466
VEGA: 10
Homologene: 9571
Cryl1
Name: crystallin, lambda 1
Synonyms: A230106J09Rik, 1110025H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 68631
VEGA: 14
Homologene: 9322
Entpd1
Name: ectonucleoside triphosphate diphosphohydrolase 1
Synonyms: Cd39, 2610206B08Rik, ectoapyrase, NTPDase-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 12495
HGNC: HGNC:3363
Homologene: 20423
Fam57b
Name: family with sequence similarity 57, member B
Synonyms: A330104J06Rik, 1500016O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68952
Homologene: 69491
Padi3
Name: peptidyl arginine deiminase, type III
Synonyms: Pdi3, Pad3, PAD type III
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18601
Homologene: 7882
Acsl6
Name: acyl-CoA synthetase long-chain family member 6
Synonyms: A330035H04Rik, Lacsl, Facl6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216739
Homologene: 100939
Cabyr
Name: calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
Synonyms: CBP86, 4933421A18Rik, 1700016C01Rik, FSP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 71132
Homologene: 49299
9230109A22Rik
Name: RIKEN cDNA 9230109A22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
Olfr788
Name: olfactory receptor 788
Synonyms: GA_x6K02T2PULF-11151514-11152449, MOR111-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 258544
Homologene: 74200
Zc2hc1b
Name: zinc finger, C2HC-type containing 1B
Synonyms: Fam164b, 4930519B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 75122
VEGA: 10
Homologene: 77965
Dipk1a
Name: divergent protein kinase domain 1A
Synonyms: 2900024C23Rik, Fam69a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 67266
Homologene: 12104
Nr2f6
Name: nuclear receptor subfamily 2, group F, member 6
Synonyms: COUP-TF3, EAR2, Erbal2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13864
HGNC: HGNC:7977
Homologene: 7706
Pcdhgb5
Name: protocadherin gamma subfamily B, 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93702
HGNC: HGNC:8712
Homologene: 55773
Gm5535
Name: predicted gene 5535
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 433481
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 53,926,201 bp
  • A to G, chromosome 1 at 105,546,710 bp
  • A to G, chromosome 2 at 35,752,406 bp
  • C to A, chromosome 2 at 58,463,017 bp
  • C to T, chromosome 2 at 82,985,310 bp
  • C to A, chromosome 2 at 144,174,572 bp
  • T to G, chromosome 4 at 112,625,879 bp
  • C to T, chromosome 4 at 118,569,641 bp
  • G to A, chromosome 4 at 140,795,843 bp
  • A to G, chromosome 4 at 155,900,156 bp
  • A to G, chromosome 5 at 3,558,544 bp
  • A to G, chromosome 5 at 81,794,513 bp
  • TAAGCA to TA, chromosome 5 at 88,637,332 bp
  • T to C, chromosome 5 at 107,140,504 bp
  • C to G, chromosome 5 at 107,909,663 bp
  • C to T, chromosome 5 at 112,802,469 bp
  • A to G, chromosome 5 at 134,559,174 bp
  • A to T, chromosome 6 at 86,718,073 bp
  • T to C, chromosome 6 at 119,446,431 bp
  • A to T, chromosome 6 at 124,061,326 bp
  • A to G, chromosome 6 at 124,432,009 bp
  • A to G, chromosome 7 at 30,440,175 bp
  • A to G, chromosome 7 at 66,330,670 bp
  • T to C, chromosome 7 at 120,369,147 bp
  • A to G, chromosome 7 at 126,827,488 bp
  • A to T, chromosome 8 at 36,512,049 bp
  • A to T, chromosome 8 at 71,374,538 bp
  • A to C, chromosome 9 at 3,001,041 bp
  • G to A, chromosome 9 at 44,089,183 bp
  • A to G, chromosome 9 at 87,015,567 bp
  • T to C, chromosome 9 at 106,434,639 bp
  • G to A, chromosome 9 at 106,978,738 bp
  • C to T, chromosome 10 at 13,153,526 bp
  • A to G, chromosome 10 at 81,293,063 bp
  • A to G, chromosome 10 at 86,811,531 bp
  • T to A, chromosome 10 at 107,821,941 bp
  • T to C, chromosome 10 at 129,473,078 bp
  • G to A, chromosome 11 at 54,327,138 bp
  • T to C, chromosome 12 at 28,691,325 bp
  • G to A, chromosome 12 at 41,452,387 bp
  • A to C, chromosome 12 at 41,452,388 bp
  • T to C, chromosome 12 at 76,328,826 bp
  • T to C, chromosome 13 at 23,486,387 bp
  • A to T, chromosome 14 at 57,313,012 bp
  • T to C, chromosome 15 at 25,138,950 bp
  • C to T, chromosome 15 at 79,737,511 bp
  • T to G, chromosome 15 at 83,544,134 bp
  • G to A, chromosome 17 at 30,800,547 bp
  • G to A, chromosome 17 at 35,873,879 bp
  • A to C, chromosome 17 at 65,861,568 bp
  • A to T, chromosome 17 at 74,641,782 bp
  • A to G, chromosome 17 at 74,662,690 bp
  • A to G, chromosome 18 at 12,751,439 bp
  • A to T, chromosome 18 at 32,841,904 bp
  • A to G, chromosome 18 at 37,731,532 bp
  • A to G, chromosome 18 at 37,974,674 bp
  • T to C, chromosome 19 at 12,919,905 bp
  • G to A, chromosome 19 at 40,711,275 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5482 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043043-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.