Strain Name:
C57BL/6J-MtgxR5495Btlr/Mmmh
Stock Number:
043056-MU
Citation ID:
RRID:MMRRC_043056-MU
Other Names:
R5495 (G1), C57BL/6J-MtgxR5495Btlr
Major Collection:

Gene Information

Nfat5
Name: nuclear factor of activated T cells 5
Synonyms: OREBP, TonEBP, nfatz, B130038B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 54446
HGNC: HGNC:7774
Homologene: 4811
Aldh1l1
Name: aldehyde dehydrogenase 1 family, member L1
Synonyms: 1810048F20Rik, Fthfd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 107747
HGNC: HGNC:3978
Homologene: 122031
Atp1a1
Name: ATPase, Na+/K+ transporting, alpha 1 polypeptide
Synonyms: Atpa-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11928
HGNC: HGNC:799
Homologene: 564
Auts2
Name: autism susceptibility candidate 2
Synonyms: 2700063G02Rik, D830032G16Rik, A730011F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319974
Homologene: 22907
Fancl
Name: Fanconi anemia, complementation group L
Synonyms: Pog, B230118H11Rik, Phf9, 2010322C19Rik, gcd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67030
Homologene: 9987
Rab11fip3
Name: RAB11 family interacting protein 3 (class II)
Synonyms: Rab11-FIP3, D030060O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 215445
Homologene: 49396
Dgkd
Name: diacylglycerol kinase, delta
Synonyms: dgkd-2, DGKdelta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227333
HGNC: HGNC:2851
Homologene: 100054
Casp12
Name: caspase 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12364
Homologene: 7654
Lmbr1
Name: limb region 1
Synonyms: 1110048D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56873
Homologene: 49706
Leng8
Name: leukocyte receptor cluster (LRC) member 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232798
Homologene: 13612
Cdan1
Name: congenital dyserythropoietic anemia, type I (human)
Synonyms: CDA-I, 1500015A01Rik, CDA1, codanin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68968
HGNC: HGNC:1713
Homologene: 16324
Nr4a2
Name: nuclear receptor subfamily 4, group A, member 2
Synonyms: Nurr1, RNR-1, HZF-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18227
HGNC: HGNC:7981
Homologene: 4509
Vnn1
Name: vanin 1
Synonyms: pantetheinase, V-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22361
Homologene: 32130
Chrd
Name: chordin
Synonyms: Chd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12667
HGNC: HGNC:1949
Homologene: 2774
Sptbn5
Name: spectrin beta, non-erythrocytic 5
Synonyms: Spnb5, EG640524
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 640524
Homologene: 41150
Arhgap29
Name: Rho GTPase activating protein 29
Synonyms: Parg1, B130017I01Rik, 6720461J18Rik, C76601
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 214137
Homologene: 3539
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22635
Homologene: 124417
Prl6a1
Name: prolactin family 6, subfamily a, member 1
Synonyms: PLP-B, Prlpb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 19111
Homologene: 49261
Egflam
Name: EGF-like, fibronectin type III and laminin G domains
Synonyms: pikachurin, nectican
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 268780
Homologene: 65044
Parp10
Name: poly (ADP-ribose) polymerase family, member 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 671535
Homologene: 53133
Rfc4
Name: replication factor C (activator 1) 4
Synonyms: A1, RFC37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 106344
HGNC: HGNC:9972
Homologene: 6288
Taar4
Name: trace amine-associated receptor 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 209513
Homologene: 45509
D630003M21Rik
Name: RIKEN cDNA D630003M21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228846
Homologene: 18598
Mug2
Name: murinoglobulin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17837
Homologene: 136663
Zswim8
Name: zinc finger SWIM-type containing 8
Synonyms: 2310021P13Rik, 4832404P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 268721
VEGA: 14
Homologene: 34313
Lgals12
Name: lectin, galactose binding, soluble 12
Synonyms: galectin-related inhibitor of proliferation, galectin-12, GRIP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 56072
Homologene: 10462
Ndor1
Name: NADPH dependent diflavin oxidoreductase 1
Synonyms: NR1, 4930447P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 78797
Homologene: 7144
Ugt1a6a
Name: UDP glucuronosyltransferase 1 family, polypeptide A6A
Synonyms: UGT1.6, Ugt1a6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 94284
Homologene: 85959
Impa1
Name: inositol (myo)-1(or 4)-monophosphatase 1
Synonyms: 2900059K10Rik, 2610002K09Rik, lithium-sensitive myo-inositol monophosphatase A1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 55980
HGNC: HGNC:6050
Homologene: 4043
Thsd7b
Name: thrombospondin, type I, domain containing 7B
Synonyms: 1700074E13Rik, D130067I03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210417
Homologene: 18180
Galc
Name: galactosylceramidase
Synonyms: 2310068B06Rik, A930008M05Rik, galactocerebrosidase, Gacy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 14420
VEGA: 12
HGNC: HGNC:4115
Homologene: 124
Olfr139
Name: olfactory receptor 139
Synonyms: GA_x6K02T2P1NL-4202012-4201065, MOR255-2, M5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259005
Homologene: 77386
Galnt15
Name: polypeptide N-acetylgalactosaminyltransferase 15
Synonyms: 4631401E18Rik, Galntl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 78754
Homologene: 14286
Serpinb12
Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12
Synonyms: 2300003F07Rik, 4833409F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71869
Homologene: 23631
Fkbp7
Name: FK506 binding protein 7
Synonyms: FKBP23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14231
HGNC: HGNC:3723
Homologene: 22568
Tdpoz4
Name: TD and POZ domain containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 399675
Homologene: 130121
Ogfod1
Name: 2-oxoglutarate and iron-dependent oxygenase domain containing 1
Synonyms: 4930415J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 270086
Homologene: 41238
Larp1b
Name: La ribonucleoprotein domain family, member 1B
Synonyms: Larp2, 4933421B21Rik, 1700108L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 214048
Homologene: 103869
Olfr957
Name: olfactory receptor 957
Synonyms: MOR171-12, GA_x6K02T2PVTD-33208209-33207274
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258740
VEGA: 9
Bcl11a
Name: B cell CLL/lymphoma 11A (zinc finger protein)
Synonyms: D930021L15Rik, COUP-TF interacting protein 1, mouse myeloid leukemia gene, Evi9c, 2810047E18Rik, Evi9b, Evi9, CTIP1, Evi9a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14025
Homologene: 11284
Lrat
Name: lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
Synonyms: 1300010A18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 79235
HGNC: HGNC:6685
Homologene: 3483
S100a7l2
Name: S100 calcium binding protein A7 like 2
Synonyms: 9130204L05Rik, LOC229550
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229550
Homologene: 135857
Olfr710
Name: olfactory receptor 710
Synonyms: MOR260-3, GA_x6K02T2PBJ9-9325348-9324416
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258594
Homologene: 27218
Ccdc59
Name: coiled-coil domain containing 59
Synonyms: D10Ertd718e, 2300004H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 52713
Homologene: 32208
Gm7932
Name: predicted gene 7932
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 666105
Gm8730
Name: predicted pseudogene 8730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 667618
Gm13757
Name: predicted gene 13757
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Pcdha11
Name: protocadherin alpha 11
Synonyms: Crnr7, Cnr7, A830022B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 12942
HGNC: HGNC:8665
Homologene: 75095
A730035I17Rik
Name: RIKEN cDNA A730035I17 gene
Synonyms: Gm34285
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 102637492
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 87,926,872 bp
  • A to T, chromosome 1 at 88,139,024 bp
  • T to C, chromosome 1 at 106,956,421 bp
  • T to A, chromosome 1 at 129,595,833 bp
  • T to C, chromosome 2 at 25,251,692 bp
  • T to C, chromosome 2 at 57,112,375 bp
  • T to C, chromosome 2 at 76,663,294 bp
  • T to C, chromosome 2 at 88,446,057 bp
  • G to A, chromosome 2 at 120,046,484 bp
  • A to C, chromosome 2 at 120,722,930 bp
  • C to T, chromosome 2 at 158,220,511 bp
  • A to G, chromosome 3 at 10,326,170 bp
  • G to T, chromosome 3 at 41,035,822 bp
  • C to A, chromosome 3 at 82,896,982 bp
  • A to T, chromosome 3 at 91,090,295 bp
  • A to T, chromosome 3 at 93,797,499 bp
  • T to G, chromosome 3 at 101,591,425 bp
  • T to G, chromosome 3 at 122,014,929 bp
  • A to T, chromosome 5 at 29,346,853 bp
  • A to G, chromosome 5 at 98,185,306 bp
  • G to A, chromosome 5 at 131,440,513 bp
  • A to G, chromosome 5 at 137,470,408 bp
  • A to T, chromosome 6 at 48,862,875 bp
  • T to C, chromosome 6 at 90,596,995 bp
  • A to T, chromosome 6 at 122,079,650 bp
  • T to A, chromosome 7 at 4,142,843 bp
  • C to A, chromosome 7 at 106,944,492 bp
  • C to A, chromosome 8 at 94,064,278 bp
  • A to G, chromosome 8 at 102,865,515 bp
  • A to G, chromosome 8 at 107,368,447 bp
  • T to A, chromosome 9 at 5,353,797 bp
  • T to C, chromosome 9 at 39,511,145 bp
  • T to A, chromosome 10 at 23,898,564 bp
  • A to T, chromosome 10 at 23,961,283 bp
  • A to G, chromosome 10 at 105,845,378 bp
  • T to A, chromosome 11 at 24,165,042 bp
  • C to G, chromosome 11 at 26,397,801 bp
  • G to A, chromosome 11 at 74,044,785 bp
  • A to G, chromosome 12 at 98,231,414 bp
  • T to C, chromosome 13 at 27,312,671 bp
  • A to G, chromosome 14 at 20,722,286 bp
  • A to G, chromosome 14 at 32,029,817 bp
  • T to A, chromosome 15 at 7,251,241 bp
  • T to G, chromosome 15 at 76,243,166 bp
  • T to C, chromosome 16 at 20,737,424 bp
  • T to C, chromosome 16 at 23,122,254 bp
  • T to A, chromosome 17 at 26,016,143 bp
  • A to G, chromosome 18 at 37,011,026 bp
  • C to T, chromosome 19 at 7,604,130 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5495 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043056-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.