Beutler Mutagenetix

Strain Name:
C57BL/6J-MtgxR5534Btlr/Mmmh
Stock Number:
043092-MU
Citation ID:
RRID:MMRRC_043092-MU
Other Names:
R5534 (G1), C57BL/6J-MtgxR5534Btlr
Major Collection:

Gene Information

Sema6d
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
Synonyms: Sema6D-2, Sema6D-4, Sema6D-1, Sema6D-6, 1110067B02Rik, Sema6D-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 214968
Homologene: 16195
Otx1
Name: orthodenticle homeobox 1
Synonyms: A730044F23Rik, jv
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 18423
HGNC: HGNC:8521
Homologene: 7875
Ank2
Name: ankyrin 2, brain
Synonyms: Ankyrin-2, Gm4392, Ank-2, ankyrin B, Ankyrin-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 109676
HGNC: HGNC:493
Homologene: null
Snx17
Name: sorting nexin 17
Synonyms: 5830447M19Rik, b2b1625.1Clo, D5Ertd260e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 266781
Homologene: 8838
Efemp1
Name: epidermal growth factor-containing fibulin-like extracellular matrix protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216616
HGNC: HGNC:3218
Homologene: 3028
Ep400
Name: E1A binding protein p400
Synonyms: 1700020J09Rik, mDomino, p400
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 75560
Homologene: 38779
Rps8
Name: ribosomal protein S8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 20116
Homologene: 133143
Sema3f
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
Synonyms: Semak, Sema IV
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20350
Homologene: 20885
Dock6
Name: dedicator of cytokinesis 6
Synonyms: C330023D02Rik, 4931431C02Rik, 2410095B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319899
VEGA: 9
Homologene: 83291
Tut7
Name: terminal uridylyl transferase 7
Synonyms: Zcchc6, Tent3b, 6030448M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 214290
VEGA: 13
Homologene: 51941
Cnot4
Name: CCR4-NOT transcription complex, subunit 4
Synonyms: Not4, Not4hp, Not4h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 53621
HGNC: HGNC:7880
Homologene: 40870
Ptpn23
Name: protein tyrosine phosphatase, non-receptor type 23
Synonyms: PTP-TD14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 104831
Homologene: 135706
Rras2
Name: related RAS viral (r-ras) oncogene 2
Synonyms: 2610016H24Rik, TC21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 66922
Homologene: 6945
Pold1
Name: polymerase (DNA directed), delta 1, catalytic subunit
Synonyms: 125kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18971
HGNC: HGNC:9175
Homologene: 2014
Nedd1
Name: neural precursor cell expressed, developmentally down-regulated gene 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 17997
VEGA: 10
HGNC: HGNC:7723
Homologene: 7439
Ccdc141
Name: coiled-coil domain containing 141
Synonyms: 2610301F02Rik, CAMDI, ENSMUSG00000075261
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 545428
Homologene: 52149
Mmp16
Name: matrix metallopeptidase 16
Synonyms: Membrane type 3-MMP, MT3-MMP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 17389
HGNC: HGNC:7162
Homologene: 55939
Dsp
Name: desmoplakin
Synonyms: 5730453H04Rik, DP, 2300002E22Rik, rul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Rnd2
Name: Rho family GTPase 2
Synonyms: Rohn, Arhn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11858
Homologene: 21123
Med13
Name: mediator complex subunit 13
Synonyms: Trap240, 1110067M05Rik, Thrap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 327987
Homologene: 21067
Clca4b
Name: chloride channel accessory 4B
Synonyms: AI747448
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99709
HGNC: HGNC:2018
Homologene: 40808
Adam18
Name: a disintegrin and metallopeptidase domain 18
Synonyms: Adam27, Dtgn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13524
HGNC: HGNC:196
Homologene: 74941
Jmjd6
Name: jumonji domain containing 6
Synonyms: PSR, 5730436I23Rik, Ptdsr, PtdSerR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 107817
Homologene: 9046
Kirrel
Name: kirre like nephrin family adhesion molecule 1
Synonyms: Neph1, Kirrel1, 6720469N11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 170643
Homologene: 10089
Pfkp
Name: phosphofructokinase, platelet
Synonyms: 9330125N24Rik, PFK-C, 1200015H23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 56421
HGNC: HGNC:8878
Homologene: 20579
Coq10b
Name: coenzyme Q10B
Synonyms: 1500041J02Rik, 9530077A17Rik, 1700030I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 67876
Homologene: 6916
Cep72
Name: centrosomal protein 72
Synonyms: 4933440J22Rik, 2610029E11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 74470
VEGA: 13
Homologene: 10027
Col4a4
Name: collagen, type IV, alpha 4
Synonyms: E130010M05Rik, [a]4(IV)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12829
HGNC: HGNC:2206
Homologene: 20071
Ltbr
Name: lymphotoxin B receptor
Synonyms: Ltar, LT beta-R, TNF-R-III, TNFRrp, TNFCR, TNFR2-RP, LTbetaR, Tnfbr, Tnfrsf3, LT-beta receptor, TNF receptor-related protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 17000
HGNC: HGNC:6718
Homologene: 1753
Slc9c1
Name: solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
Synonyms: LOC208169, spermNHE, Slc9a10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 208169
Homologene: 19505
Col11a2
Name: collagen, type XI, alpha 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12815
HGNC: HGNC:2187
Homologene: 22547
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Lama3
Name: laminin, alpha 3
Synonyms: nicein, 150kDa, [a]3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Fbxo30
Name: F-box protein 30
Synonyms: 1700026A16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71865
Homologene: 12959
Cplane1
Name: ciliogenesis and planar polarity effector 1
Synonyms: Hug, Jbts17, b2b012Clo, 2410089E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 73692
Homologene: 11315
Carmil3
Name: capping protein regulator and myosin 1 linker 3
Synonyms: Lrrc16b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 268747
VEGA: 14
Homologene: 74564
Zan
Name: zonadhesin
Synonyms: Zan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 22635
Homologene: 124417
Cass4
Name: Cas scaffolding protein family member 4
Synonyms: F730031O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 320664
Homologene: 75128
Esyt1
Name: extended synaptotagmin-like protein 1
Synonyms: Fam62a, Mbc2, vp115
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 23943
VEGA: 10
Homologene: 40794
Ankrd50
Name: ankyrin repeat domain 50
Synonyms: E430012K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99696
Homologene: 129859
Myh3
Name: myosin, heavy polypeptide 3, skeletal muscle, embryonic
Synonyms: Myhse, Myhs-e, MyHC-emb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17883
HGNC: HGNC:7573
Homologene: 20553
Gna11
Name: guanine nucleotide binding protein, alpha 11
Synonyms: Dsk7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 14672
HGNC: HGNC:4379
Homologene: 20474
Tbc1d2b
Name: TBC1 domain family, member 2B
Synonyms: 1810061M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 67016
Homologene: 56694
Snrpe
Name: small nuclear ribonucleoprotein E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20643
Homologene: 37729
Ush1c
Name: USH1 protein network component harmonin
Synonyms: harmonin, 2010016F01Rik, Usher syndrome 1C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72088
Homologene: 77476
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: Mll2, Mll4, C430014K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Pcnx2
Name: pecanex homolog 2
Synonyms: E330039K12Rik, Pcnxl2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 270109
HGNC: HGNC:8736
Homologene: 8987
Rin3
Name: Ras and Rab interactor 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217835
Homologene: 11748
Wdr90
Name: WD repeat domain 90
Synonyms: 3230401M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 106618
Homologene: 27066
Grid2
Name: glutamate receptor, ionotropic, delta 2
Synonyms: GluRdelta2, B230104L07Rik, tpr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14804
HGNC: HGNC:4576
Homologene: 74399
Ankmy2
Name: ankyrin repeat and MYND domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217473
VEGA: 12
Homologene: 10662
Armc2
Name: armadillo repeat containing 2
Synonyms: 2610018I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 213402
Homologene: 41848
Slc22a27
Name: solute carrier family 22, member 27
Synonyms: mOAT6 related protein, AB056442
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 171405
Homologene: 77136
Apcdd1
Name: adenomatosis polyposis coli down-regulated 1
Synonyms: EIG180, Drapc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 494504
VEGA: 18
Homologene: 77420
Smg8
Name: smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
Synonyms: 1200011M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 74133
Homologene: 32393
Gm13084
Name: predicted gene 13084
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381569
HGNC: null
Homologene: 77858
Ccdc33
Name: coiled-coil domain containing 33
Synonyms: LOC382077, 4930535E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382077
Homologene: 19641
Wnt11
Name: wingless-type MMTV integration site family, member 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 22411
Homologene: 20970
Ankmy1
Name: ankyrin repeat and MYND domain containing 1
Synonyms: 4930483I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241158
Homologene: 9561
Zfp763
Name: zinc finger protein 763
Synonyms: 1700065O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 73451
HGNC: null
Homologene: 66274
Edil3
Name: EGF-like repeats and discoidin I-like domains 3
Synonyms: developmental endothelial locus-1, Del1, Del-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13612
HGNC: HGNC:3173
Homologene: 21166
Olfr1295
Name: olfactory receptor 1295
Synonyms: GA_x6K02T2Q125-72616944-72616006, MOR248-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258398
HGNC: null
Homologene: 74058
Poglut2
Name: protein O-glucosyltransferase 2
Synonyms: 5730416C13Rik, EP58, 1810049A15Rik, Kdel1, Kdelc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 72050
Homologene: 11367
Olfr237-ps1
Name: olfactory receptor 237, pseudogene 1
Synonyms: Olfr438, GA_x6K02T08UK8-1-481, MOR261-4, GA_x6K02T2P3E9-4404793-4403861
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 258648
Homologene: 88438
Scrn2
Name: secernin 2
Synonyms: SES2, D11Moh48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217140
Homologene: 26698
Gbp11
Name: guanylate binding protein 11
Synonyms: Gm7141
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 634650
Homologene: 128731
Slc36a3
Name: solute carrier family 36 (proton/amino acid symporter), member 3
Synonyms: TRAMD2, PAT3, tramdorin2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 215332
Homologene: 76175
Otud3
Name: OTU domain containing 3
Synonyms: 3110030K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 73162
Homologene: 66103
Olfr199
Name: olfactory receptor 199
Synonyms: GA_x54KRFPKG5P-55430495-55429569, MOR182-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 404310
HGNC: null
Homologene: 37011
Meltf
Name: melanotransferrin
Synonyms: melanotransferrin, MTf, Mfi2, CD228
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 30060
VEGA: 16
HGNC: HGNC:7037
Homologene: 4335
R3hdm4
Name: R3H domain containing 4
Synonyms: C030046I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 109284
VEGA: 10
Homologene: 16343
Olfr1009
Name: olfactory receptor 1009
Synonyms: GA_x6K02T2Q125-47195323-47196267, MOR175-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258565
HGNC: null
Homologene: 17297
Rhbdd2
Name: rhomboid domain containing 2
Synonyms: Usmg1, 0610011L13Rik, Rhbdl7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 215160
Homologene: 32481
Shd
Name: src homology 2 domain-containing transforming protein D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 20420
VEGA: 17
Homologene: 7537
Gm5292
Name: predicted gene 5292
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 384179
HGNC: null
Homologene: null
Pole4
Name: polymerase (DNA-directed), epsilon 4 (p12 subunit)
Synonyms: 5830430F06Rik, 2400007P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 66979
Homologene: 41339
Mgat1
Name: mannoside acetylglucosaminyltransferase 1
Synonyms: Mgat-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17308
HGNC: HGNC:7044
Homologene: 1804
Pcdhga7
Name: protocadherin gamma subfamily A, 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93715
HGNC: HGNC:8705
Homologene: 36377
Trav9n-4
Name: T cell receptor alpha variable 9N-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 279882
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 44,112,677 bp
  • T to C, chromosome 1 at 55,064,200 bp
  • T to C, chromosome 1 at 82,487,517 bp
  • T to C, chromosome 1 at 92,886,720 bp
  • A to T, chromosome 1 at 133,606,473 bp
  • A to G, chromosome 2 at 77,057,897 bp
  • T to C, chromosome 2 at 85,721,987 bp
  • T to C, chromosome 2 at 111,565,004 bp
  • T to C, chromosome 2 at 124,659,815 bp
  • G to T, chromosome 2 at 172,426,768 bp
  • A to G, chromosome 3 at 38,456,082 bp
  • G to A, chromosome 3 at 87,090,518 bp
  • A to T, chromosome 3 at 126,947,298 bp
  • A to T, chromosome 3 at 144,915,466 bp
  • A to T, chromosome 4 at 18,110,452 bp
  • G to C, chromosome 4 at 117,155,155 bp
  • A to G, chromosome 4 at 138,897,583 bp
  • G to T, chromosome 4 at 143,812,599 bp
  • C to T, chromosome 5 at 31,196,502 bp
  • A to T, chromosome 5 at 43,944,223 bp
  • A to T, chromosome 5 at 105,331,038 bp
  • A to T, chromosome 5 at 110,698,947 bp
  • A to G, chromosome 5 at 135,635,261 bp
  • A to G, chromosome 5 at 137,438,451 bp
  • A to G, chromosome 6 at 35,078,004 bp
  • A to G, chromosome 6 at 43,153,633 bp
  • A to T, chromosome 6 at 63,503,361 bp
  • A to G, chromosome 6 at 82,652,134 bp
  • G to A, chromosome 6 at 125,312,794 bp
  • A to G, chromosome 7 at 44,538,619 bp
  • A to G, chromosome 7 at 46,221,423 bp
  • T to C, chromosome 7 at 98,839,142 bp
  • G to A, chromosome 7 at 114,050,415 bp
  • T to A, chromosome 8 at 24,665,514 bp
  • T to G, chromosome 8 at 125,838,015 bp
  • G to A, chromosome 9 at 21,803,076 bp
  • A to G, chromosome 9 at 58,117,167 bp
  • C to T, chromosome 9 at 90,227,506 bp
  • T to C, chromosome 9 at 107,684,412 bp
  • A to G, chromosome 9 at 110,392,741 bp
  • T to C, chromosome 10 at 11,289,665 bp
  • G to T, chromosome 10 at 41,922,667 bp
  • C to T, chromosome 10 at 79,912,458 bp
  • A to T, chromosome 10 at 81,531,133 bp
  • A to T, chromosome 10 at 92,695,032 bp
  • C to T, chromosome 10 at 128,519,460 bp
  • A to G, chromosome 11 at 21,996,296 bp
  • T to C, chromosome 11 at 28,867,758 bp
  • T to C, chromosome 11 at 49,261,149 bp
  • C to G, chromosome 11 at 55,142,769 bp
  • A to T, chromosome 11 at 67,097,044 bp
  • A to T, chromosome 11 at 86,319,365 bp
  • A to T, chromosome 11 at 87,085,470 bp
  • A to G, chromosome 11 at 97,030,925 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • A to G, chromosome 11 at 116,840,426 bp
  • T to C, chromosome 11 at 118,052,770 bp
  • A to G, chromosome 12 at 36,182,492 bp
  • T to C, chromosome 12 at 102,387,632 bp
  • C to A, chromosome 13 at 6,648,583 bp
  • A to C, chromosome 13 at 38,195,842 bp
  • A to G, chromosome 13 at 59,788,553 bp
  • T to C, chromosome 13 at 74,062,216 bp
  • A to G, chromosome 13 at 89,199,474 bp
  • A to G, chromosome 14 at 53,294,899 bp
  • A to G, chromosome 14 at 55,494,890 bp
  • C to A, chromosome 15 at 8,228,835 bp
  • A to G, chromosome 15 at 98,837,357 bp
  • T to A, chromosome 16 at 31,890,814 bp
  • T to A, chromosome 16 at 45,556,614 bp
  • T to C, chromosome 16 at 59,216,040 bp
  • T to C, chromosome 17 at 25,851,481 bp
  • A to C, chromosome 17 at 33,021,794 bp
  • C to T, chromosome 17 at 34,051,024 bp
  • G to T, chromosome 17 at 55,971,577 bp
  • A to T, chromosome 18 at 12,553,210 bp
  • A to C, chromosome 18 at 37,716,278 bp
  • T to C, chromosome 18 at 62,937,034 bp
  • T to C, chromosome 19 at 7,926,631 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5534 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043092-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.