Strain Name:
C57BL/6J-MtgxR5602Btlr/Mmmh
Stock Number:
043154-MU
Citation ID:
RRID:MMRRC_043154-MU
Other Names:
R5602 (G1), C57BL/6J-MtgxR5602Btlr
Major Collection:

Gene Information

Utrn
Name: utrophin
Synonyms: G-utrophin, DRP, Dmdl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22288
VEGA: 10
Homologene: 21398
Cd36
Name: CD36 molecule
Synonyms: Scarb3, FAT, fatty acid translocase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12491
HGNC: HGNC:1663
Homologene: 73871
Slco1a5
Name: solute carrier organic anion transporter family, member 1a5
Synonyms: Slc21a7, Oatp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 108096
Homologene: 56603
Becn1
Name: beclin 1, autophagy related
Synonyms: Atg6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 56208
HGNC: HGNC:1034
Homologene: 2794
Jak2
Name: Janus kinase 2
Synonyms: C81284
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 16452
VEGA: 19
HGNC: HGNC:6192
Homologene: 21033
Rorb
Name: RAR-related orphan receptor beta
Synonyms: Rorbeta, Nr1f2, RZR-beta, hstp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225998
Homologene: 38250
Ube2o
Name: ubiquitin-conjugating enzyme E2O
Synonyms: B230113M03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217342
Homologene: 11113
Map4
Name: microtubule-associated protein 4
Synonyms: Mtap4, MAP 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17758
HGNC: HGNC:6862
Homologene: 1780
Cop1
Name: COP1, E3 ubiquitin ligase
Synonyms: Rfwd2, Cop1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 26374
Homologene: 115565
Washc2
Name: WASH complex subunit 2`
Synonyms: Fam21, C530005J20Rik, D6Wsu116e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28006
Homologene: 41686
Fmn2
Name: formin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 54418
Homologene: 137334
Stk38l
Name: serine/threonine kinase 38 like
Synonyms: 4930473A22Rik, Ndr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232533
Homologene: 56299
Tmem104
Name: transmembrane protein 104
Synonyms: C630005D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 320534
Homologene: 9802
Cnot4
Name: CCR4-NOT transcription complex, subunit 4
Synonyms: Not4, Not4hp, Not4h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 53621
HGNC: HGNC:7880
Homologene: 40870
Ap2a2
Name: adaptor-related protein complex 2, alpha 2 subunit
Synonyms: 2410074K14Rik, Adtab, L25, alpha-adaptin C, alpha-C adaptin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11772
HGNC: HGNC:562
Homologene: 5335
Naa25
Name: N(alpha)-acetyltransferase 25, NatB auxiliary subunit
Synonyms: 4833422K13Rik, C330023M02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231713
Homologene: 6891
Srrm2
Name: serine/arginine repetitive matrix 2
Synonyms: 5033413A03Rik, SRm300
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 75956
Safb2
Name: scaffold attachment factor B2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224902
Homologene: 35210
Pdik1l
Name: PDLIM1 interacting kinase 1 like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230809
Homologene: 36977
Ipo9
Name: importin 9
Synonyms: 0710008K06Rik, Imp9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226432
Homologene: 5874
Mlh1
Name: mutL homolog 1
Synonyms: colon cancer, nonpolyposis type 2, 1110035C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17350
HGNC: HGNC:7127
Homologene: 208
Gpr3
Name: G-protein coupled receptor 3
Synonyms: Gpcr3, Gpcr21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 14748
HGNC: HGNC:4484
Homologene: 31303
Pfas
Name: phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
Synonyms: Sofa, 4432409B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237823
HGNC: HGNC:8863
Homologene: 5970
Adam19
Name: a disintegrin and metallopeptidase domain 19 (meltrin beta)
Synonyms: Mltnb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11492
HGNC: HGNC:197
Homologene: 74925
Zfp507
Name: zinc finger protein 507
Synonyms: 1810022O10Rik, A230056M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 668501
Homologene: 8942
Dock2
Name: dedicator of cyto-kinesis 2
Synonyms: MBC, Hch, CED-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 94176
HGNC: HGNC:2988
Homologene: 37984
Sall3
Name: spalt like transcription factor 3
Synonyms: Salt, Spalt, Msal-1, B130022O04Rik, Msal
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 20689
VEGA: 18
Homologene: 18142
Ccr7
Name: chemokine (C-C motif) receptor 7
Synonyms: Ebi1h, EBI1, Cmkbr7, CD197
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12775
HGNC: HGNC:1608
Homologene: 1387
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Adal
Name: adenosine deaminase-like
Synonyms: 4930578F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75894
Homologene: 13827
Scaf1
Name: SR-related CTD-associated factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233208
Wdr24
Name: WD repeat domain 24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268933
Homologene: 6870
Gm17067
Name: predicted gene 17067
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101056115
Ggt7
Name: gamma-glutamyltransferase 7
Synonyms: 6330563L03Rik, 1110017C11Rik, Ggtl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 207182
HGNC: HGNC:4259
Homologene: 70866
Slc20a1
Name: solute carrier family 20, member 1
Synonyms: Glvr1, PiT-1, Glvr-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20515
Homologene: 38049
Olfr954
Name: olfactory receptor 954
Synonyms: MOR171-53, GA_x6K02T2PVTD-33158015-33158950, MOR171-42
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258328
VEGA: 9
Homologene: 71961
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: E130113P14Rik, bl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231470
Homologene: 23516
Supv3l1
Name: suppressor of var1, 3-like 1 (S. cerevisiae)
Synonyms: 6330443E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 338359
Homologene: 2386
Arhgef4
Name: Rho guanine nucleotide exchange factor (GEF) 4
Synonyms: Asef, C230030N03Rik, 9330140K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226970
HGNC: HGNC:684
Homologene: 49414
Col15a1
Name: collagen, type XV, alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 12819
HGNC: HGNC:2192
Homologene: 1396
B4galnt3
Name: beta-1,4-N-acetyl-galactosaminyl transferase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330406
Homologene: 18328
Tll2
Name: tolloid-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 24087
VEGA: 19
Homologene: 56545
Xkr4
Name: X-linked Kx blood group related 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 497097
Homologene: 45848
Scgb2b27
Name: secretoglobin, family 2B, member 27
Synonyms: Abpbg27, Abpbg5, C2a, Abpb, Scgb2b5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233099
Homologene: 83171
Rasgrf1
Name: RAS protein-specific guanine nucleotide-releasing factor 1
Synonyms: Grfbeta, Grf1, CDC25, CDC25Mm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 19417
HGNC: HGNC:9875
Homologene: 74972
Prob1
Name: proline rich basic protein 1
Synonyms: LOC381148, Gm1614
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 381148
Homologene: 83773
4921509C19Rik
Name: RIKEN cDNA 4921509C19 gene
Synonyms: LOC381389
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381393
Homologene: 72396
4932414N04Rik
Name: RIKEN cDNA 4932414N04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75721
Homologene: 138468
Vmn2r109
Name: vomeronasal 2, receptor 109
Synonyms: EG627814
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627814
Homologene: 129678
AA474408
Name: expressed sequence AA474408
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
Rsph9
Name: radial spoke head 9 homolog (Chlamydomonas)
Synonyms: 1700027N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 75564
Homologene: 12606
1700057G04Rik
Name: RIKEN cDNA 1700057G04 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 78459
Homologene: 134508
Olfr969
Name: olfactory receptor 969
Synonyms: GA_x6K02T2PVTD-33492981-33493916, MOR171-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258823
VEGA: 9
Homologene: 121532
Galm
Name: galactose mutarotase
Synonyms: aldose 1-epimerase, A530057M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 319625
Homologene: 71795
Acyp2
Name: acylphosphatase 2, muscle type
Synonyms: 2310004B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75572
HGNC: HGNC:180
Homologene: 41776
Tmem151b
Name: transmembrane protein 151B
Synonyms: LOC210573
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 210573
VEGA: 17
Homologene: 19365
Zfp768
Name: zinc finger protein 768
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233890
Homologene: 11650
Spata21
Name: spermatogenesis associated 21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 329972
Homologene: 18639
Asb5
Name: ankyrin repeat and SOCs box-containing 5
Synonyms: 1110018D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 76294
Homologene: 12637
Ighv11-2
Name: immunoglobulin heavy variable V11-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 780818
Pcdhgb4
Name: protocadherin gamma subfamily B, 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93701
HGNC: HGNC:8711
Homologene: 74507
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 3,216,528 bp
  • C to A, chromosome 1 at 34,807,337 bp
  • G to A, chromosome 1 at 135,402,245 bp
  • T to A, chromosome 1 at 159,324,839 bp
  • A to T, chromosome 1 at 174,699,712 bp
  • A to T, chromosome 2 at 68,748,368 bp
  • T to C, chromosome 2 at 121,142,285 bp
  • G to T, chromosome 2 at 125,321,741 bp
  • A to G, chromosome 2 at 129,200,469 bp
  • G to A, chromosome 2 at 151,473,539 bp
  • A to G, chromosome 2 at 155,490,999 bp
  • G to A, chromosome 4 at 47,312,087 bp
  • T to C, chromosome 4 at 133,210,494 bp
  • A to G, chromosome 4 at 134,284,269 bp
  • C to T, chromosome 4 at 141,096,899 bp
  • T to C, chromosome 5 at 17,814,792 bp
  • A to G, chromosome 5 at 96,737,021 bp
  • A to G, chromosome 5 at 121,420,495 bp
  • C to T, chromosome 6 at 35,051,529 bp
  • T to A, chromosome 6 at 116,248,095 bp
  • G to A, chromosome 6 at 120,215,025 bp
  • T to A, chromosome 6 at 142,275,529 bp
  • C to A, chromosome 6 at 146,758,500 bp
  • A to T, chromosome 7 at 34,013,106 bp
  • G to T, chromosome 7 at 35,776,238 bp
  • T to A, chromosome 7 at 42,708,415 bp
  • A to G, chromosome 7 at 45,007,583 bp
  • C to T, chromosome 7 at 110,060,907 bp
  • T to A, chromosome 7 at 127,344,632 bp
  • A to T, chromosome 7 at 141,604,942 bp
  • A to G, chromosome 8 at 54,585,939 bp
  • A to T, chromosome 9 at 39,462,030 bp
  • T to A, chromosome 9 at 39,796,194 bp
  • T to C, chromosome 9 at 89,911,571 bp
  • G to A, chromosome 9 at 92,352,668 bp
  • T to C, chromosome 9 at 110,052,700 bp
  • A to T, chromosome 9 at 111,252,878 bp
  • T to C, chromosome 10 at 12,750,095 bp
  • G to A, chromosome 10 at 62,430,592 bp
  • C to T, chromosome 11 at 30,506,354 bp
  • C to A, chromosome 11 at 34,254,391 bp
  • T to C, chromosome 11 at 46,136,315 bp
  • A to T, chromosome 11 at 68,991,045 bp
  • G to T, chromosome 11 at 99,145,489 bp
  • T to C, chromosome 11 at 101,288,952 bp
  • G to A, chromosome 11 at 115,205,124 bp
  • G to A, chromosome 11 at 116,539,086 bp
  • G to A, chromosome 12 at 114,048,479 bp
  • A to G, chromosome 12 at 114,048,657 bp
  • A to T, chromosome 17 at 20,540,671 bp
  • G to A, chromosome 17 at 23,819,337 bp
  • G to A, chromosome 17 at 25,825,967 bp
  • A to G, chromosome 17 at 45,545,600 bp
  • G to T, chromosome 17 at 46,134,983 bp
  • C to A, chromosome 17 at 56,575,630 bp
  • T to A, chromosome 17 at 80,150,139 bp
  • C to T, chromosome 18 at 35,654,026 bp
  • T to C, chromosome 18 at 37,721,644 bp
  • T to C, chromosome 18 at 80,972,812 bp
  • T to A, chromosome 19 at 18,977,937 bp
  • T to A, chromosome 19 at 29,298,339 bp
  • T to A, chromosome 19 at 41,104,981 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5602 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043154-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.