Strain Name:
C57BL/6J-MtgxR5692Btlr/Mmmh
Stock Number:
043179-MU
Citation ID:
RRID:MMRRC_043179-MU
Other Names:
R5692 (G1), C57BL/6J-MtgxR5692Btlr
Major Collection:

Gene Information

Sulf2
Name: sulfatase 2
Synonyms: 2010004N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72043
Homologene: 10313
Med1
Name: mediator complex subunit 1
Synonyms: TRAP 220, TRAP220, CRSP210, DRIP205, Pparbp, l11Jus15, PBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 19014
HGNC: HGNC:9234
Homologene: 21002
Pafah2
Name: platelet-activating factor acetylhydrolase 2
Synonyms: 2310074E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100163
HGNC: HGNC:8579
Homologene: 37309
Rab3gap2
Name: RAB3 GTPase activating protein subunit 2
Synonyms: 1110059F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98732
Homologene: 40842
Ago3
Name: argonaute RISC catalytic subunit 3
Synonyms: argonaute 3, eIF2C3, C130014L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 214150
Homologene: 49799
Aldh16a1
Name: aldehyde dehydrogenase 16 family, member A1
Synonyms: 2410004H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69748
Homologene: 34938
Trf
Name: transferrin
Synonyms: Tfn, HP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22041
Homologene: 68153
Bcam
Name: basal cell adhesion molecule
Synonyms: B-CAM, 1200005K12Rik, Lu
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 57278
HGNC: HGNC:6722
Homologene: 21149
Mtch1
Name: mitochondrial carrier 1
Synonyms: 2310034O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56462
Homologene: 22807
Tph2
Name: tryptophan hydroxylase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216343
Homologene: 27831
Pcdhb18
Name: protocadherin beta 18
Synonyms: Pcdhb9, PcdhbR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93889
Homologene: 137649
Clec4d
Name: C-type lectin domain family 4, member d
Synonyms: mMCL, Mpcl, Clecsf8, mcl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 17474
Homologene: 7844
Pcdh17
Name: protocadherin 17
Synonyms: LOC219228, C030033F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219228
VEGA: 14
Homologene: 8700
Dph2
Name: DPH2 homolog
Synonyms: 9130020C19Rik, Dph2l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67728
HGNC: HGNC:3004
Homologene: 1060
Egln3
Name: egl-9 family hypoxia-inducible factor 3
Synonyms: SM-20, 2610021G09Rik, Phd3, Hif-p4h-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 112407
Homologene: 32531
Slc35e2
Name: solute carrier family 35, member E2
Synonyms: A530082C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 320541
Homologene: 84987
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Fhad1
Name: forkhead-associated (FHA) phosphopeptide binding domain 1
Synonyms: 2900090M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329977
Homologene: 77947
Snrk
Name: SNF related kinase
Synonyms: SNRK, 2010012F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20623
Homologene: 9797
Fetub
Name: fetuin beta
Synonyms: 2310011O17Rik, D17980
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 59083
VEGA: 16
HGNC: HGNC:3658
Homologene: 8660
Vmn2r18
Name: vomeronasal 2, receptor 18
Synonyms: EG632671
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 632671
Sacs
Name: sacsin
Synonyms: E130115J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50720
Dennd4b
Name: DENN/MADD domain containing 4B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229541
Homologene: 28281
Nnmt
Name: nicotinamide N-methyltransferase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 18113
HGNC: HGNC:7861
Homologene: 4496
Arhgap26
Name: Rho GTPase activating protein 26
Synonyms: 1810044B20Rik, 2610010G17Rik, 4933432P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 71302
Homologene: 36349
Mrc2
Name: mannose receptor, C type 2
Synonyms: novel lectin, Endo180, uPARAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17534
Homologene: 4408
Pcdhb15
Name: protocadherin beta 15
Synonyms: Pcdhb7, PcdhbO
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93886
HGNC: HGNC:8692
Homologene: 32429
Zfp709
Name: zinc finger protein 709
Synonyms: GIOT-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 236193
Homologene: 136795
Gfm1
Name: G elongation factor, mitochondrial 1
Synonyms: D3Wsu133e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 28030
Homologene: 6449
Slc7a11
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
Synonyms: System xc, xc, xCT, sut, 9930009M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 26570
Homologene: 22684
1700128F08Rik
Name: RIKEN cDNA 1700128F08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 76669
VEGA: 9
Opn1sw
Name: opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
Synonyms: Blue/UV Opsin, Blue Opsin, SWS opsin, Short Wavelength Sensitive opsin, S Opsin, Blue Cone Opsin, Bcp, UV cone pigment
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12057
HGNC: HGNC:1012
Homologene: 1291
Ly9
Name: lymphocyte antigen 9
Synonyms: T100, Lgp100, CD229, SLAMF3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17085
HGNC: HGNC:6730
Homologene: 1759
Isg15
Name: ISG15 ubiquitin-like modifier
Synonyms: G1p2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100038882
VEGA: 4
HGNC: HGNC:4053
Homologene: 48326
Optc
Name: opticin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269120
HGNC: HGNC:8158
Homologene: 8652
Aqp7
Name: aquaporin 7
Synonyms: AQP7L, AQPap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11832
HGNC: HGNC:640
Homologene: 48000
Zfp607b
Name: zinc finger protein 607B
Synonyms: C030039L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 112415
Homologene: 134321
Psme2
Name: proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
Synonyms: PA28b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19188
HGNC: HGNC:9569
Homologene: 86889
B130055M24Rik
Name: RIKEN cDNA B130055M24 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 654803
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 133,900,976 bp
  • GCCTTTGGGGGACAATTCC to GCC, chromosome 1 at 171,605,187 bp
  • C to T, chromosome 1 at 185,283,501 bp
  • C to T, chromosome 2 at 76,797,858 bp
  • C to A, chromosome 2 at 166,081,506 bp
  • C to G, chromosome 3 at 50,372,331 bp
  • T to G, chromosome 3 at 67,435,622 bp
  • T to C, chromosome 3 at 90,277,783 bp
  • G to A, chromosome 4 at 41,035,510 bp
  • C to A, chromosome 4 at 117,889,792 bp
  • T to C, chromosome 4 at 126,355,069 bp
  • C to T, chromosome 4 at 134,411,890 bp
  • T to A, chromosome 4 at 141,963,457 bp
  • C to T, chromosome 4 at 155,610,026 bp
  • A to T, chromosome 4 at 156,199,822 bp
  • A to G, chromosome 5 at 151,562,259 bp
  • G to A, chromosome 6 at 29,379,841 bp
  • T to C, chromosome 6 at 123,268,145 bp
  • A to G, chromosome 7 at 19,765,431 bp
  • G to T, chromosome 7 at 27,703,464 bp
  • A to G, chromosome 7 at 45,147,799 bp
  • T to C, chromosome 7 at 127,448,899 bp
  • C to T, chromosome 8 at 71,890,155 bp
  • G to A, chromosome 9 at 8,221,990 bp
  • G to T, chromosome 9 at 48,603,480 bp
  • T to C, chromosome 9 at 103,226,125 bp
  • G to C, chromosome 9 at 122,166,320 bp
  • A to T, chromosome 10 at 115,184,827 bp
  • G to T, chromosome 11 at 98,156,380 bp
  • T to A, chromosome 11 at 105,336,642 bp
  • T to C, chromosome 12 at 54,180,661 bp
  • A to G, chromosome 14 at 55,588,550 bp
  • T to C, chromosome 14 at 61,207,839 bp
  • C to T, chromosome 14 at 84,448,540 bp
  • C to T, chromosome 16 at 22,932,331 bp
  • C to T, chromosome 17 at 29,340,863 bp
  • T to C, chromosome 18 at 37,474,449 bp
  • G to A, chromosome 18 at 37,490,484 bp
  • T to A, chromosome 18 at 39,121,892 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5692 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043179-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.