Strain Name:
C57BL/6J-MtgxR5805Btlr/Mmmh
Stock Number:
043212-MU
Citation ID:
RRID:MMRRC_043212-MU
Other Names:
R5805 (G1), C57BL/6J-MtgxR5805Btlr
Major Collection:

Gene Information

Kifc2
Name: kinesin family member C2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16581
VEGA: 15
Homologene: 7800
Dnm2
Name: dynamin 2
Synonyms: b2b2159Clo, Dyn2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13430
HGNC: HGNC:2974
Homologene: 90883
Ntrk1
Name: neurotrophic tyrosine kinase, receptor, type 1
Synonyms: TrkA, Tkr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18211
HGNC: HGNC:8031
Homologene: 1898
Rnf10
Name: ring finger protein 10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 50849
Homologene: 40990
Tnrc6a
Name: trinucleotide repeat containing 6a
Synonyms: 2010321I05Rik, CAGH26, Tnrc6, D130023A07Rik, 3110054G10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233833
Homologene: 41399
Micu1
Name: mitochondrial calcium uptake 1
Synonyms: Cbara1, C730016L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216001
HGNC: HGNC:1530
Homologene: 4431
U2surp
Name: U2 snRNP-associated SURP domain containing
Synonyms: 2610101N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67958
Homologene: 13964
Plcg2
Name: phospholipase C, gamma 2
Synonyms: Plcg-2, PLCgamma2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234779
HGNC: HGNC:9066
Homologene: 55671
Stag1
Name: stromal antigen 1
Synonyms: SA-1, Scc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20842
Homologene: 21191
Lypla1
Name: lysophospholipase 1
Synonyms: Gm39587, Pla1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18777
HGNC: HGNC:6737
Homologene: 100781
Adam8
Name: a disintegrin and metallopeptidase domain 8
Synonyms: MS2, CD156a, E430039A18Rik, CD156
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11501
HGNC: HGNC:215
Homologene: 74384
Garem1
Name: GRB2 associated regulator of MAPK1 subtype 1
Synonyms: Garem, Fam59a, LOC381126
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 381126
VEGA: 18
Homologene: 11237
Kcnn2
Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Synonyms: small conductance calcium-activated potassium channel 2, fri, bc, SK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 140492
HGNC: HGNC:6291
Homologene: 135651
Mef2a
Name: myocyte enhancer factor 2A
Synonyms: A430079H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17258
HGNC: HGNC:6993
Homologene: 4080
Atf7
Name: activating transcription factor 7
Synonyms: C130020M04Rik, 1110012F10Rik, 9430065F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223922
HGNC: HGNC:792
Homologene: 4994
Arhgap33
Name: Rho GTPase activating protein 33
Synonyms: NOMA-GAP, Snx26, Tcgap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233071
Homologene: 76448
Sidt2
Name: SID1 transmembrane family, member 2
Synonyms: CGI-40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214597
Homologene: 22943
Itfg1
Name: integrin alpha FG-GAP repeat containing 1
Synonyms: D8Wsu49e, 2310047C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 71927
Homologene: 12423
Zfp979
Name: zinc finger protein 979
Synonyms: 2610305D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 112422
Homologene: 133076
Baiap3
Name: BAI1-associated protein 3
Synonyms: LOC381076
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 545192
HGNC: HGNC:948
Homologene: 20844
Srcap
Name: Snf2-related CREBBP activator protein
Synonyms: D030022P06Rik, F630004O05Rik, B930091H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043597
Homologene: 38213
Usf3
Name: upstream transcription factor family member 3
Synonyms: Gm608, LOC385650, LOC207806, 5530400K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 207806
Homologene: 19504
Chia1
Name: chitinase, acidic 1
Synonyms: 2200003E03Rik, YNL, AMCase, Chia
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 81600
Homologene: 75168
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: PC5/6A, b2b585Clo, SPC6, b2b1549Clo, PC6, PC5A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Synonyms: BC006779
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 229003
Homologene: 14118
Stxbp5
Name: syntaxin binding protein 5 (tomosyn)
Synonyms: tomosyn 1, 0710001E20Rik, 4930565N16Rik, LGL3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 78808
Homologene: 16402
Ciz1
Name: CDKN1A interacting zinc finger protein 1
Synonyms: 0610038H21Rik, 2900056O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 68379
Homologene: 8112
Vmn2r15
Name: vomeronasal 2, receptor 15
Synonyms: EG211223
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 211223
Homologene: 129606
Ros1
Name: Ros1 proto-oncogene
Synonyms: c-ros, Ros-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19886
Homologene: 2207
Krt18
Name: keratin 18
Synonyms: K18, Krt1-18, CK18, Endo B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16668
VEGA: 15
HGNC: HGNC:6430
Homologene: 55448
Abca5
Name: ATP-binding cassette, sub-family A (ABC1), member 5
Synonyms: ABC13, B930033A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217265
HGNC: HGNC:35
Homologene: 10263
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: Dnahc7b, LOC227058
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227058
Homologene: 41287
Ccdc40
Name: coiled-coil domain containing 40
Synonyms: B930008I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 207607
Homologene: 27890
Olfr155
Name: olfactory receptor 155
Synonyms: GA_x6K02T2N78B-16092200-16091241, OR37A, mOR37a, MOR262-14, Olfr37a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 29845
HGNC: HGNC:8276
Homologene: 84331
Doc2b
Name: double C2, beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13447
HGNC: HGNC:2986
Homologene: 20796
Slc66a2
Name: solute carrier family 66 member 2
Synonyms: 4933425L21Rik, Pqlc1, 2310009N05Rik, 5730564E11Rik, C78974
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 66943
Homologene: 32623
Olfr1212
Name: olfactory receptor 1212
Synonyms: GA_x6K02T2Q125-50437014-50437949, MOR233-17, MOR233-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258241
Homologene: 66154
Mpv17l
Name: Mpv17 transgene, kidney disease mutant-like
Synonyms: M-LP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 93734
Homologene: 13547
Gm15448
Name: predicted gene 15448
Synonyms: ENSMUSG00000074419
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100041146
HGNC: HGNC:6607
Homologene: 134028
Rnf19b
Name: ring finger protein 19B
Synonyms: 4930534K13Rik, 4930555L03Rik, Ibrdc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 75234
Homologene: 34999
Spag1
Name: sperm associated antigen 1
Synonyms: TPR-containing protein involved in spermatogenesis, tpis
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 26942
VEGA: 15
Homologene: 8081
Gpr132
Name: G protein-coupled receptor 132
Synonyms: G2a, G2 accumulation
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 56696
VEGA: 12
Homologene: 8350
Olfr61
Name: olfactory receptor 61
Synonyms: IH7, MOR253-1, GA_x6K02T2PBJ9-42783826-42784758
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18362
Homologene: 79374
Rpl17-ps10
Name: ribosomal protein L17, pseudogene 10
Synonyms: Gm10294
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100042880
Homologene: 138783
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 4,830,294 bp
  • T to C, chromosome 1 at 46,177,407 bp
  • T to C, chromosome 2 at 32,367,396 bp
  • G to A, chromosome 2 at 88,958,641 bp
  • C to A, chromosome 2 at 181,240,508 bp
  • G to A, chromosome 3 at 87,780,172 bp
  • A to G, chromosome 3 at 106,128,476 bp
  • T to C, chromosome 4 at 43,855,152 bp
  • A to G, chromosome 4 at 129,058,824 bp
  • T to C, chromosome 4 at 147,613,610 bp
  • T to C, chromosome 5 at 109,286,940 bp
  • A to T, chromosome 5 at 115,244,068 bp
  • G to A, chromosome 7 at 3,822,623 bp
  • T to C, chromosome 7 at 30,526,414 bp
  • T to C, chromosome 7 at 67,251,668 bp
  • T to A, chromosome 7 at 72,649,229 bp
  • T to C, chromosome 7 at 123,170,076 bp
  • T to A, chromosome 7 at 127,542,039 bp
  • T to A, chromosome 7 at 139,985,881 bp
  • T to A, chromosome 7 at 140,638,471 bp
  • A to T, chromosome 8 at 85,766,972 bp
  • T to C, chromosome 8 at 117,598,495 bp
  • A to G, chromosome 9 at 21,467,669 bp
  • G to A, chromosome 9 at 45,942,199 bp
  • C to T, chromosome 9 at 95,479,304 bp
  • T to A, chromosome 9 at 100,796,778 bp
  • T to C, chromosome 10 at 9,900,586 bp
  • G to T, chromosome 10 at 52,123,289 bp
  • A to C, chromosome 10 at 59,827,306 bp
  • C to A, chromosome 10 at 74,230,259 bp
  • A to G, chromosome 11 at 75,772,538 bp
  • C to T, chromosome 11 at 110,279,390 bp
  • T to C, chromosome 11 at 119,246,080 bp
  • G to A, chromosome 12 at 112,852,796 bp
  • T to C, chromosome 15 at 36,200,284 bp
  • C to T, chromosome 15 at 76,662,153 bp
  • T to A, chromosome 15 at 102,031,300 bp
  • A to T, chromosome 15 at 102,557,587 bp
  • A to G, chromosome 16 at 13,942,149 bp
  • A to G, chromosome 16 at 44,220,746 bp
  • T to A, chromosome 17 at 25,247,515 bp
  • C to T, chromosome 18 at 21,148,435 bp
  • T to A, chromosome 18 at 45,683,131 bp
  • C to T, chromosome 18 at 80,263,443 bp
  • T to C, chromosome 19 at 17,456,829 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5805 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043212-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.