Strain Name:
C57BL/6J-MtgxR5901Btlr/Mmmh
Stock Number:
043239-MU
Citation ID:
RRID:MMRRC_043239-MU
Other Names:
R5901 (G1), C57BL/6J-MtgxR5901Btlr
Major Collection:

Gene Information

Drd2
Name: dopamine receptor D2
Synonyms: D2 receptor, D2R, Drd-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 13489
VEGA: 9
HGNC: HGNC:3023
Homologene: 22561
Ccr2
Name: chemokine (C-C motif) receptor 2
Synonyms: CC-CKR-2, CKR2B, CKR2A, CCR2B, CCR2A, CKR2, Cmkbr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12772
HGNC: HGNC:1603
Homologene: 537
Ly6k
Name: lymphocyte antigen 6 complex, locus K
Synonyms: 3110035B01Rik, 2410015A16Rik, mLy-6K
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 76486
Homologene: 130772
Dop1b
Name: DOP1 leucine zipper like protein B
Synonyms: 0610038M01Rik, 2610510B01Rik, Dopey2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 70028
VEGA: 16
HGNC: HGNC:1291
Homologene: 21068
Fancd2
Name: Fanconi anemia, complementation group D2
Synonyms: 2410150O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 211651
HGNC: HGNC:3585
Homologene: 13212
Matk
Name: megakaryocyte-associated tyrosine kinase
Synonyms: Ntk, HYL, CHK, Csk homologous kinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17179
HGNC: HGNC:6906
Homologene: 48104
Sema4b
Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
Synonyms: SemC, Semac
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20352
Homologene: 8426
Tmem39a
Name: transmembrane protein 39a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67846
Homologene: 9985
Pdcd11
Name: programmed cell death 11
Synonyms: ALG-4, 1110021I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18572
VEGA: 19
Homologene: 74968
Mcm10
Name: minichromosome maintenance 10 replication initiation factor
Synonyms: C330019M07Rik, 2410041F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70024
Homologene: 41275
Bdp1
Name: B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
Synonyms: TFIIIB150, TFIIIB90, TAF3B1, TFC5, Tfnr, G630013P12Rik, B130055N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 544971
Homologene: 34582
Otof
Name: otoferlin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 83762
HGNC: HGNC:8515
Homologene: 12892
Ppfia1
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
Synonyms: liprin, C030014K08Rik, Liprin-alpha1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233977
HGNC: HGNC:9245
Homologene: 20802
Scyl2
Name: SCY1-like 2 (S. cerevisiae)
Synonyms: D10Ertd802e, CVAK104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 213326
Homologene: 13349
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: A930005E13Rik, LOC381562, D930005K06Rik, 1810009A16Rik, Zubr1, p600
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69116
Homologene: 10804
Atp6v1b1
Name: ATPase, H+ transporting, lysosomal V1 subunit B1
Synonyms: Vpp-3, Vpp3, Atp6b1, lysosomal 56/58kDa, D630039P21Rik, D630030L16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 110935
HGNC: HGNC:853
Homologene: 68198
Kif24
Name: kinesin family member 24
Synonyms: 4933425J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 109242
Homologene: 52346
Rad54b
Name: RAD54 homolog B (S. cerevisiae)
Synonyms: E130016E03Rik, E130016E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 623474
Homologene: 8240
Mlph
Name: melanophilin
Synonyms: Slac-2a, D1Wsu84e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 171531
Homologene: 11465
Kif17
Name: kinesin family member 17
Synonyms: N-4 kinesin, 5930435E01Rik, Kif17b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16559
Homologene: 5883
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: A530024P18Rik, 2310008C07Rik, 2310003D02Rik, mXin beta, myomaxin, Cmya3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241431
Homologene: 19388
Zfand4
Name: zinc finger, AN1-type domain 4
Synonyms: 2810002D23Rik, Anubl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67492
VEGA: 6
Homologene: 18373
Megf10
Name: multiple EGF-like-domains 10
Synonyms: LOC240312, 3000002B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 70417
Homologene: 23771
Efcab7
Name: EF-hand calcium binding domain 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230500
Homologene: 19952
Aqp8
Name: aquaporin 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11833
HGNC: HGNC:642
Homologene: 68166
Stard9
Name: START domain containing 9
Synonyms: N-3 kinesin, Kif16a, 4831403C07Rik, E230025N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668880
Homologene: 130712
Vmn2r78
Name: vomeronasal 2, receptor 78
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 637896
Homologene: 115466
Fbxw16
Name: F-box and WD-40 domain protein 16
Synonyms: 7420402K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320083
Homologene: 110776
Atg9b
Name: autophagy related 9B
Synonyms: LOC213948, Apg9l2, eONE, Nos3as
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 213948
Homologene: 72638
B4gat1
Name: beta-1,4-glucuronyltransferase 1
Synonyms: BETA3GNT1, iGNT, 1500032M01Rik, B3gnt6, B3gnt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 108902
VEGA: 19
Homologene: 38239
Ankra2
Name: ankyrin repeat, family A (RFXANK-like), 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 68558
Homologene: 11312
Adamts15
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235130
VEGA: 9
Homologene: 8610
Smarcd3
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
Synonyms: 1500001J14Rik, BAF60C, 2210409C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66993
Homologene: 2314
Xkr4
Name: X-linked Kx blood group related 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 497097
Homologene: 45848
Cfap43
Name: cilia and flagella associated protein 43
Synonyms: 4930428C11Rik, 4632415N18Rik, 4930463G05Rik, D19Ertd652e, Wdr96
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 100048534
Homologene: 36425
Stat5b
Name: signal transducer and activator of transcription 5B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20851
Homologene: 55718
Tmem117
Name: transmembrane protein 117
Synonyms: B930062P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 320709
VEGA: 15
Homologene: 12992
Vmn1r7
Name: vomeronasal 1 receptor 7
Synonyms: Gm5568, V1rc31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 434016
Homologene: 83427
Slc16a11
Name: solute carrier family 16 (monocarboxylic acid transporters), member 11
Synonyms: MNCb-2717
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216867
Homologene: 27409
Faim
Name: Fas apoptotic inhibitory molecule
Synonyms: Faim-L, Faim-S
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 23873
Homologene: 8018
Mapk10
Name: mitogen-activated protein kinase 10
Synonyms: p493F12, JNK3, Serk2, C230008H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26414
HGNC: HGNC:6872
Homologene: 56439
2300003K06Rik
Name: RIKEN cDNA 2300003K06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 100502865
Acyp2
Name: acylphosphatase 2, muscle type
Synonyms: 2310004B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 75572
HGNC: HGNC:180
Homologene: 41776
Yae1d1
Name: Yae1 domain containing 1
Synonyms: 1600012F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 67008
VEGA: 13
Homologene: 10615
Sar1b
Name: secretion associated Ras related GTPase 1B
Synonyms: 2900019I22Rik, 2310075M17Rik, Sara2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66397
Homologene: 90905
Tas2r119
Name: taste receptor, type 2, member 119
Synonyms: mt2r19, Tas2r19, mGR19, T2R19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 57254
Homologene: 10480
BB019430
Name: expressed sequence BB019430
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 103505
VEGA: 10
Calhm3
Name: calcium homeostasis modulator 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240669
VEGA: 19
Ighv1-57
Name: immunoglobulin heavy variable V1-57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 780937
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 3,216,678 bp
  • T to C, chromosome 1 at 90,939,814 bp
  • A to G, chromosome 2 at 4,999,626 bp
  • A to T, chromosome 2 at 67,513,066 bp
  • A to C, chromosome 2 at 120,701,370 bp
  • G to A, chromosome 4 at 11,595,919 bp
  • A to T, chromosome 4 at 41,428,604 bp
  • T to A, chromosome 4 at 99,909,744 bp
  • T to C, chromosome 4 at 138,298,332 bp
  • T to A, chromosome 4 at 139,451,254 bp
  • A to G, chromosome 5 at 24,392,019 bp
  • A to G, chromosome 5 at 24,591,053 bp
  • T to C, chromosome 5 at 30,374,979 bp
  • A to G, chromosome 5 at 102,913,292 bp
  • T to C, chromosome 6 at 57,024,606 bp
  • A to G, chromosome 6 at 83,758,357 bp
  • T to C, chromosome 6 at 113,549,365 bp
  • T to C, chromosome 6 at 116,288,123 bp
  • A to G, chromosome 7 at 80,224,967 bp
  • T to C, chromosome 7 at 86,954,588 bp
  • G to A, chromosome 7 at 123,462,584 bp
  • A to G, chromosome 7 at 144,477,978 bp
  • C to T, chromosome 9 at 30,902,490 bp
  • T to A, chromosome 9 at 49,406,959 bp
  • T to C, chromosome 9 at 98,992,142 bp
  • T to C, chromosome 9 at 109,441,217 bp
  • C to T, chromosome 9 at 124,106,202 bp
  • T to A, chromosome 10 at 58,704,192 bp
  • T to C, chromosome 10 at 81,260,198 bp
  • C to T, chromosome 10 at 89,660,262 bp
  • C to T, chromosome 11 at 30,506,354 bp
  • C to T, chromosome 11 at 51,779,749 bp
  • A to G, chromosome 11 at 70,216,346 bp
  • T to A, chromosome 11 at 99,837,337 bp
  • A to T, chromosome 11 at 100,804,907 bp
  • C to T, chromosome 12 at 115,268,441 bp
  • A to G, chromosome 13 at 17,989,615 bp
  • A to G, chromosome 13 at 98,271,136 bp
  • A to G, chromosome 13 at 100,066,060 bp
  • T to A, chromosome 15 at 32,177,786 bp
  • A to T, chromosome 15 at 74,798,580 bp
  • T to A, chromosome 15 at 94,714,958 bp
  • T to C, chromosome 16 at 38,573,206 bp
  • A to G, chromosome 16 at 93,769,751 bp
  • G to A, chromosome 18 at 57,277,108 bp
  • T to A, chromosome 19 at 5,039,213 bp
  • T to C, chromosome 19 at 47,128,332 bp
  • T to C, chromosome 19 at 47,157,613 bp
  • T to C, chromosome 19 at 47,897,099 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5901 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043239-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.