Strain Name:
C57BL/6J-MtgxR5967Btlr/Mmmh
Stock Number:
043248-MU
Citation ID:
RRID:MMRRC_043248-MU
Other Names:
R5967 (G1), C57BL/6J-MtgxR5967Btlr
Major Collection:

Gene Information

Cdc25a
Name: cell division cycle 25A
Synonyms: D9Ertd393e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12530
HGNC: HGNC:1725
Homologene: 1355
Gtf2h3
Name: general transcription factor IIH, polypeptide 3
Synonyms: 5033417D07Rik, BTF2, D5Ertd679e, 34kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 209357
HGNC: HGNC:4657
Homologene: 1160
Kif20a
Name: kinesin family member 20A
Synonyms: Rabkinesin-6, Rab6kifl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 19348
VEGA: 18
HGNC: HGNC:9787
Homologene: 38093
Dapp1
Name: dual adaptor for phosphotyrosine and 3-phosphoinositides 1
Synonyms: Bam32
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 26377
Homologene: 32138
Agrn
Name: agrin
Synonyms: NMF380, Agrin, nmf380
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 11603
HGNC: HGNC:329
Homologene: 27907
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, Bruce, A430032G04Rik, D630005A10Rik, A430040A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Nup214
Name: nucleoporin 214
Synonyms: D2H9S46E, CAN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227720
HGNC: HGNC:8064
Homologene: 38008
Itprid2
Name: ITPR interacting domain containing 2
Synonyms: SPAG13, CS-1, CS1, KRAP, Ssfa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70599
Homologene: 4912
Ncor2
Name: nuclear receptor co-repressor 2
Synonyms: SMRTe, SMRT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20602
HGNC: HGNC:7673
Homologene: 31370
Rad23a
Name: RAD23 homolog A, nucleotide excision repair protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 19358
HGNC: HGNC:9812
Homologene: 48322
Gpsm1
Name: G-protein signalling modulator 1 (AGS3-like, C. elegans)
Synonyms: 1810037C22Rik, Ags3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67839
Homologene: 16987
Meaf6
Name: MYST/Esa1-associated factor 6
Synonyms: 2810036M01Rik, 2310005N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 70088
Homologene: 11240
Slit2
Name: slit guidance ligand 2
Synonyms: Slil3, Drad-1, E130320P19Rik, E030015M03Rik, b2b1200.1Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20563
Homologene: 3516
Nodal
Name: nodal
Synonyms: Tg.413d
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18119
HGNC: HGNC:7865
Homologene: 8417
Angptl2
Name: angiopoietin-like 2
Synonyms: Arp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 26360
HGNC: HGNC:490
Homologene: 22695
Ralbp1
Name: ralA binding protein 1
Synonyms: Rip1, RLIP76
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 19765
VEGA: 17
HGNC: HGNC:9841
Homologene: 4940
Gnl2
Name: guanine nucleotide binding protein-like 2 (nucleolar)
Synonyms: Ngp-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230737
Homologene: 6858
Trhde
Name: TRH-degrading enzyme
Synonyms: 9330155P21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237553
Homologene: 75007
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
C8b
Name: complement component 8, beta polypeptide
Synonyms: 4930439B20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 110382
HGNC: HGNC:1353
Homologene: 48
Scin
Name: scinderin
Synonyms: adseverin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 20259
Homologene: 36296
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 26875
Homologene: 69111
Ptprd
Name: protein tyrosine phosphatase, receptor type, D
Synonyms: 3000002J10Rik, B230219D21Rik, 1110002J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19266
HGNC: HGNC:9668
Scn7a
Name: sodium channel, voltage-gated, type VII, alpha
Synonyms: Nav2.3, NaG, Nav2, 1110034K09Rik, Scn6a, Nax
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20272
Homologene: 55706
Agl
Name: amylo-1,6-glucosidase, 4-alpha-glucanotransferase
Synonyms: 9430004C13Rik, 9630046L06Rik, 1110061O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77559
HGNC: HGNC:321
Homologene: 536
Stard9
Name: START domain containing 9
Synonyms: N-3 kinesin, Kif16a, 4831403C07Rik, E230025N21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 668880
Homologene: 130712
Ppargc1b
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 beta
Synonyms: PGC-1beta/ERRL1, 4631412G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 170826
Homologene: 15776
Gna11
Name: guanine nucleotide binding protein, alpha 11
Synonyms: Dsk7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14672
HGNC: HGNC:4379
Homologene: 20474
Txlnb
Name: taxilin beta
Synonyms: Mdp77, 2310001N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 378431
Homologene: 44534
Klc3
Name: kinesin light chain 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232943
Homologene: 14899
Myorg
Name: myogenesis regulating glycosidase (putative)
Synonyms: NET37, AI464131
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329828
Homologene: 19853
Muc3
Name: mucin 3, intestinal
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 666339
Homologene: 141159
Piwil2
Name: piwi-like RNA-mediated gene silencing 2
Synonyms: Miwi like, mili
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 57746
VEGA: 14
Homologene: 23071
1520401A03Rik
Name: RIKEN cDNA 1520401A03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 320309
Prkd1
Name: protein kinase D1
Synonyms: Pkcm, PKD1, Prkcm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18760
VEGA: 12
HGNC: HGNC:9407
Homologene: 55680
Meis2
Name: Meis homeobox 2
Synonyms: Meis2, Stra10, A430109D20Rik, Mrg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17536
HGNC: HGNC:7001
Homologene: 7846
Zfp715
Name: zinc finger protein 715
Synonyms: 2610041B18Rik, mszf15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69930
Homologene: 74591
Ido2
Name: indoleamine 2,3-dioxygenase 2
Synonyms: C230043N17Rik, Ido2, Indol1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 209176
Homologene: 48830
Ceacam1
Name: carcinoembryonic antigen-related cell adhesion molecule 1
Synonyms: CD66a, MHVR1, mmCGM1, mCEA1, mmCGM2, Hv-2, Bgp, Mhv-1, Cea-7, Cea-1, Cea1, Bgp1, C-CAM, Hv2, Cea7, Cc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26365
HGNC: HGNC:1814
Homologene: 128630
Olfr514
Name: olfactory receptor 514
Synonyms: GA_x6K02T2PBJ9-11156311-11155379, MOR268-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258721
Homologene: 73956
Olfr172
Name: olfactory receptor 172
Synonyms: GA_x54KRFPKG5P-54930346-54929417, MOR184-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 259003
HGNC: HGNC:8349
Homologene: 45084
Olfr1029
Name: olfactory receptor 1029
Synonyms: GA_x6K02T2Q125-47454152-47455126, MOR198-1P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258154
Homologene: 73972
Gm4963
Name: predicted gene 4963
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 243302
Homologene: 135447
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 2 at 26,340,534 bp
  • T to C, chromosome 2 at 31,979,778 bp
  • A to G, chromosome 2 at 33,228,706 bp
  • T to A, chromosome 2 at 66,675,713 bp
  • G to T, chromosome 2 at 79,662,647 bp
  • G to A, chromosome 2 at 85,976,191 bp
  • G to A, chromosome 2 at 115,864,309 bp
  • T to A, chromosome 2 at 120,706,894 bp
  • T to A, chromosome 3 at 116,793,708 bp
  • T to A, chromosome 3 at 137,981,476 bp
  • G to A, chromosome 4 at 41,497,830 bp
  • A to G, chromosome 4 at 76,099,520 bp
  • A to G, chromosome 4 at 104,793,333 bp
  • A to G, chromosome 4 at 125,041,030 bp
  • G to A, chromosome 4 at 125,107,656 bp
  • G to A, chromosome 4 at 156,175,103 bp
  • A to T, chromosome 5 at 14,540,655 bp
  • A to T, chromosome 5 at 47,985,164 bp
  • C to T, chromosome 5 at 124,584,297 bp
  • C to T, chromosome 5 at 125,068,984 bp
  • T to A, chromosome 5 at 137,146,637 bp
  • C to T, chromosome 5 at 137,993,241 bp
  • C to A, chromosome 7 at 19,395,982 bp
  • C to T, chromosome 7 at 25,474,742 bp
  • T to C, chromosome 7 at 43,299,148 bp
  • C to T, chromosome 7 at 108,825,714 bp
  • A to G, chromosome 8 at 16,081,634 bp
  • A to G, chromosome 8 at 24,540,672 bp
  • T to C, chromosome 8 at 84,838,939 bp
  • G to A, chromosome 9 at 109,892,144 bp
  • A to G, chromosome 10 at 17,799,420 bp
  • G to T, chromosome 10 at 61,423,667 bp
  • A to G, chromosome 10 at 81,530,809 bp
  • T to A, chromosome 10 at 114,567,134 bp
  • C to T, chromosome 12 at 40,077,538 bp
  • A to T, chromosome 12 at 50,364,550 bp
  • A to T, chromosome 14 at 70,390,564 bp
  • G to T, chromosome 16 at 58,760,362 bp
  • C to A, chromosome 17 at 23,712,358 bp
  • A to G, chromosome 17 at 65,864,279 bp
  • T to C, chromosome 17 at 74,660,439 bp
  • G to T, chromosome 18 at 34,630,527 bp
  • A to G, chromosome 18 at 61,298,766 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5967 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043248-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.