Strain Name:
C57BL/6J-MtgxR5362Btlr
Stock Number:
043264-MU
Citation ID:
RRID:MMRRC_043264-MU
Other Names:
R5362 (G1)
Major Collection:

Gene Information

Nrp2
Name: neuropilin 2
Synonyms: NP2, Npn-2, Npn2, 1110048P06Rik, NP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18187
HGNC: HGNC:8005
Homologene: 2875
Ano1
Name: anoctamin 1, calcium activated chloride channel
Synonyms: Tmem16a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101772
Homologene: 75079
Ankrd17
Name: ankyrin repeat domain 17
Synonyms: 4933425K22Rik, Gtar, A130069E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 81702
Homologene: 82403
Foxj3
Name: forkhead box J3
Synonyms: C330039G02Rik, Fhd6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230700
Homologene: 35243
Trappc9
Name: trafficking protein particle complex 9
Synonyms: 4632408O18Rik, 2900005P22Rik, Nibp, TRS130, 1810044A24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 76510
VEGA: 15
Homologene: 81931
Top2a
Name: topoisomerase (DNA) II alpha
Synonyms: DNA Topoisomerase II alpha, Top-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21973
Homologene: 830
Prpf8
Name: pre-mRNA processing factor 8
Synonyms: DBF3/PRP8, Prp8, D11Bwg0410e, Sfprp8l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192159
Homologene: 4706
Elp1
Name: elongator complex protein 1
Synonyms: 3110040G09Rik, C78473, IKAP, Ikbkap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230233
HGNC: HGNC:5959
Homologene: 2699
Afg3l2
Name: AFG3-like AAA ATPase 2
Synonyms: 2310036I02Rik, par, Emv66
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 69597
VEGA: 18
HGNC: HGNC:315
Homologene: 4947
Gpc1
Name: glypican 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14733
HGNC: HGNC:4449
Homologene: 20477
C2cd5
Name: C2 calcium-dependent domain containing 5
Synonyms: C030008B15Rik, CDP138, 5730419I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74741
Homologene: 8873
Spg11
Name: SPG11, spatacsin vesicle trafficking associated
Synonyms: C530005A01Rik, 6030465E24Rik, spastic paraplegia 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 214585
Homologene: 41614
Csn2
Name: casein beta
Synonyms: CSN2, Csnb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12991
HGNC: HGNC:2447
Homologene: 1426
Carm1
Name: coactivator-associated arginine methyltransferase 1
Synonyms: Prmt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 59035
Homologene: 10990
Ccdc47
Name: coiled-coil domain containing 47
Synonyms: asp4, 2610204L23Rik, calumin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67163
Homologene: 41351
Atl2
Name: atlastin GTPase 2
Synonyms: Aip-2, 2010110I21Rik, Arl6ip2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 56298
VEGA: 17
Homologene: 56949
Svil
Name: supervillin
Synonyms: B430302E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 225115
Homologene: 25090
Dlx3
Name: distal-less homeobox 3
Synonyms: Dlx-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13393
HGNC: HGNC:2916
Homologene: 74544
Sertad4
Name: SERTA domain containing 4
Synonyms: C130018M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 214791
Homologene: 10483
Itgae
Name: integrin alpha E, epithelial-associated
Synonyms: CD103, alpha-E1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16407
HGNC: HGNC:6147
Homologene: 113560
Cfap74
Name: cilia and flagella associated protein 74
Synonyms: 2010015L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 544678
Homologene: 129584
Ptprd
Name: protein tyrosine phosphatase, receptor type, D
Synonyms: 3000002J10Rik, B230219D21Rik, 1110002J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19266
HGNC: HGNC:9668
Nkpd1
Name: NTPase, KAP family P-loop domain containing 1
Synonyms: 2310015G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 69547
Homologene: 18876
Scn7a
Name: sodium channel, voltage-gated, type VII, alpha
Synonyms: Nav2.3, NaG, Nav2, 1110034K09Rik, Scn6a, Nax
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20272
Homologene: 55706
Plekhg4
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 4
Synonyms: 4931414L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 102075
Homologene: 18516
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Kif9
Name: kinesin family member 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16578
Homologene: 65620
Izumo3
Name: IZUMO family member 3
Synonyms: 1700011H22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69314
Homologene: 122080
5530400C23Rik
Name: RIKEN cDNA 5530400C23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232426
Homologene: 79760
Col4a1
Name: collagen, type IV, alpha 1
Synonyms: Col4a-1, Del(8)Bru44H, Del(8)44H, Bru, Svc, Raw, alpha1(IV) collagen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12826
HGNC: HGNC:2202
Homologene: 20437
Cstdc1
Name: cystatin domain containing 1
Synonyms: cystatin SC, 8030411F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 78609
Homologene: 128710
Qrich2
Name: glutamine rich 2
Synonyms: LOC217341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217341
Homologene: 12951
Ranbp6
Name: RAN binding protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240614
HGNC: HGNC:9851
Homologene: 18935
Olfr600
Name: olfactory receptor 600
Synonyms: GA_x6K02T2PBJ9-6056235-6055291, MOR39-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259048
Homologene: 17476
Pex5l
Name: peroxisomal biogenesis factor 5-like
Synonyms: 1700016J08Rik, PXR2, TRIP8b, Pex2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 58869
Homologene: 9562
Vmn2r99
Name: vomeronasal 2, receptor 99
Synonyms: EG665376
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 665376
Homologene: 115024
Olfr814
Name: olfactory receptor 814
Synonyms: GA_x6K02T2PULF-11553313-11552381, MOR113-5, MOR113-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 259165
Homologene: 133585
Itga2b
Name: integrin alpha 2b
Synonyms: platelet glycoprotein IIb, GpIIb, alphaIIb, CD41, GP IIb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16399
HGNC: HGNC:6138
Homologene: 37304
Ocm
Name: oncomodulin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 18261
Homologene: 4511
Insyn2b
Name: inhibitory synaptic factor family member 2B
Synonyms: Gm6041, Fam196b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 574403
VEGA: 11
Homologene: 107175
Pou2f2
Name: POU domain, class 2, transcription factor 2
Synonyms: Oct2b, Oct2a, Otf-2, Oct-2, Otf2, Oct2d, Oct2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18987
HGNC: HGNC:9213
Homologene: 55674
Zfp62
Name: zinc finger protein 62
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 22720
Homologene: 40686
Olfr667
Name: olfactory receptor 667
Synonyms: GA_x6K02T2PBJ9-7546146-7545166, MOR34-2, MOR34-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259062
Homologene: 121559
R3hdm4
Name: R3H domain containing 4
Synonyms: C030046I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 109284
VEGA: 10
Homologene: 16343
Olfr724
Name: olfactory receptor 724
Synonyms: GA_x6K02T2PMLR-5645801-5644872, MOR247-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 258485
Homologene: 71986
Vmn1r91
Name: vomeronasal 1 receptor 91
Synonyms: Gm8442
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 667067
Homologene: 104166
Cd300lf
Name: CD300 molecule like family member F
Synonyms: Pigr3, CLM-1, IgSF13, IREM1, F730004D16Rik, DIgR2, LMIR3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246746
Homologene: 51396
Clec4a1
Name: C-type lectin domain family 4, member a1
Synonyms: mDcir4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 269799
Homologene: 72399
Fam221a
Name: family with sequence similarity 221, member A
Synonyms: D330028D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 231946
Homologene: 18214
Gm37240
Name: predicted gene, 37240
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 62,769,062 bp
  • A to T, chromosome 1 at 92,854,893 bp
  • T to C, chromosome 1 at 192,847,106 bp
  • T to C, chromosome 2 at 41,375,902 bp
  • G to A, chromosome 2 at 66,699,998 bp
  • G to T, chromosome 2 at 122,061,000 bp
  • G to T, chromosome 2 at 148,783,378 bp
  • G to A, chromosome 3 at 32,992,916 bp
  • G to A, chromosome 3 at 84,515,693 bp
  • A to C, chromosome 4 at 56,778,969 bp
  • A to T, chromosome 4 at 76,128,813 bp
  • A to T, chromosome 4 at 92,146,800 bp
  • T to A, chromosome 4 at 119,620,143 bp
  • A to G, chromosome 4 at 155,438,166 bp
  • T to A, chromosome 5 at 87,694,649 bp
  • G to A, chromosome 5 at 90,265,545 bp
  • T to C, chromosome 5 at 144,023,856 bp
  • A to G, chromosome 6 at 49,376,115 bp
  • A to G, chromosome 6 at 122,932,237 bp
  • A to T, chromosome 6 at 133,294,482 bp
  • T to C, chromosome 6 at 143,083,243 bp
  • G to A, chromosome 7 at 19,523,268 bp
  • A to T, chromosome 7 at 20,101,461 bp
  • G to A, chromosome 7 at 25,092,895 bp
  • A to G, chromosome 7 at 103,346,247 bp
  • A to G, chromosome 7 at 104,916,627 bp
  • A to C, chromosome 7 at 144,648,600 bp
  • T to C, chromosome 8 at 11,245,760 bp
  • T to A, chromosome 8 at 105,381,398 bp
  • A to G, chromosome 9 at 21,587,359 bp
  • G to A, chromosome 9 at 110,489,944 bp
  • C to T, chromosome 10 at 79,912,458 bp
  • T to C, chromosome 10 at 129,874,553 bp
  • G to A, chromosome 11 at 34,402,788 bp
  • A to T, chromosome 11 at 49,216,612 bp
  • A to G, chromosome 11 at 73,111,849 bp
  • G to A, chromosome 11 at 75,506,410 bp
  • T to C, chromosome 11 at 95,120,500 bp
  • T to C, chromosome 11 at 99,018,912 bp
  • A to G, chromosome 11 at 102,461,135 bp
  • G to A, chromosome 11 at 106,208,213 bp
  • G to T, chromosome 11 at 115,117,114 bp
  • T to C, chromosome 11 at 116,447,150 bp
  • A to G, chromosome 14 at 49,960,529 bp
  • C to T, chromosome 15 at 73,058,217 bp
  • G to T, chromosome 17 at 19,379,339 bp
  • T to C, chromosome 17 at 79,861,461 bp
  • C to T, chromosome 18 at 5,057,345 bp
  • G to T, chromosome 18 at 67,421,259 bp
  • G to T, chromosome 19 at 29,811,728 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5362 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043264-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.