Strain Name:
C57BL/6J-MtgxR5617Btlr
Stock Number:
043276-MU
Citation ID:
RRID:MMRRC_043276-MU
Other Names:
R5617 (G1)
Major Collection:

Gene Information

Ubr5
Name: ubiquitin protein ligase E3 component n-recognin 5
Synonyms: 4432411E13Rik, Edd, Edd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70790
VEGA: 15
Homologene: 9295
Plaat1
Name: phospholipase A and acyltransferase 1
Synonyms: 2810012B06Rik, A-C1, Hrasls
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 27281
Homologene: 8452
Clcnka
Name: chloride channel, voltage-sensitive Ka
Synonyms: CLC-K1, Clcnk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12733
Homologene: 65
Rabep1
Name: rabaptin, RAB GTPase binding effector protein 1
Synonyms: RAB5 effector protein, neurocrescin, rabaptin-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 54189
Homologene: 3451
Fbxo38
Name: F-box protein 38
Synonyms: 6030410I24Rik, SP329
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 107035
VEGA: 18
Homologene: 34526
Ranbp2
Name: RAN binding protein 2
Synonyms: A430087B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19386
VEGA: 10
Homologene: 87808
Slc25a17
Name: solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
Synonyms: 34kDa, PMP34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 20524
VEGA: 15
Homologene: 4637
Stim2
Name: stromal interaction molecule 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 116873
Homologene: 32490
Trio
Name: triple functional domain (PTPRF interacting)
Synonyms: Solo, 6720464I07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223435
VEGA: 15
Homologene: 20847
Htt
Name: huntingtin
Synonyms: htt, Hdh, huntingtin, IT15, HD, C430023I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15194
HGNC: HGNC:4851
Homologene: 1593
Lbr
Name: lamin B receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 98386
HGNC: HGNC:6518
Homologene: 2455
Grm2
Name: glutamate receptor, metabotropic 2
Synonyms: Gprc1b, mGluR2, 4930441L02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 108068
HGNC: HGNC:4594
Homologene: 20229
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Atp10a
Name: ATPase, class V, type 10A
Synonyms: Atp10c, pfatp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11982
Homologene: 56461
Pgm5
Name: phosphoglucomutase 5
Synonyms: 9530034F03Rik, aciculin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 226041
HGNC: HGNC:8908
Homologene: 74881
Lama3
Name: laminin, alpha 3
Synonyms: nicein, 150kDa, [a]3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 16774
HGNC: HGNC:6483
Homologene: 18279
Fam135b
Name: family with sequence similarity 135, member B
Synonyms: A830008O07Rik, 1700010C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70363
VEGA: 15
Homologene: 66605
Sptbn5
Name: spectrin beta, non-erythrocytic 5
Synonyms: Spnb5, EG640524
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 640524
Homologene: 41150
Aste1
Name: asteroid homolog 1
Synonyms: 1100001A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 66595
Homologene: 130666
Ncdn
Name: neurochondrin
Synonyms: neurochondrin-1, neurochondrin-2, norbin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 26562
Homologene: 8064
Acss3
Name: acyl-CoA synthetase short-chain family member 3
Synonyms: LOC380660, 8430416H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 380660
Homologene: 11587
Nr1h5
Name: nuclear receptor subfamily 1, group H, member 5
Synonyms: FXRB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 381463
Homologene: 131277
Parp3
Name: poly (ADP-ribose) polymerase family, member 3
Synonyms: Adprtl3, A930002C11Rik, PARP-3, Adprt3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235587
HGNC: HGNC:273
Homologene: 4005
Pou6f1
Name: POU domain, class 6, transcription factor 1
Synonyms: 2310038G18Rik, cns-1, Emb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19009
HGNC: HGNC:9224
Homologene: 7703
Krt78
Name: keratin 78
Synonyms: 2310030B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 332131
VEGA: 15
Homologene: 65261
Dennd4b
Name: DENN/MADD domain containing 4B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229541
Homologene: 28281
Map3k19
Name: mitogen-activated protein kinase kinase kinase 19
Synonyms: Ysk4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22625
Homologene: 19318
Ranbp6
Name: RAN binding protein 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 240614
HGNC: HGNC:9851
Homologene: 18935
Cenpb
Name: centromere protein B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12616
HGNC: HGNC:1852
Homologene: 1370
Vmn2r52
Name: vomeronasal 2, receptor 52
Synonyms: EG384534
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 384534
Homologene: 129605
Tmem163
Name: transmembrane protein 163
Synonyms: beta-actin::Cre, TgN(ACTB-cre)2Mrt, 2610024A01Rik, SV31, Tg(ACTB-cre)2Mrt, A-cre, Act-Cre, beta-actin-cre, creactin, beta-actin-Cre, actin-cre, beta-actin:Cre
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72160
Homologene: 12798
Osbpl5
Name: oxysterol binding protein-like 5
Synonyms: 1110006M06Rik, Obph1, ORP5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 79196
Homologene: 98024
Notum
Name: notum palmitoleoyl-protein carboxylesterase
Synonyms: 5730593N15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77583
Homologene: 45335
Olfr635
Name: olfactory receptor 635
Synonyms: MOR5-2, GA_x6K02T2PBJ9-6713641-6714588
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259122
Homologene: 133592
Slfn8
Name: schlafen 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 276950
Homologene: 45432
Cdh18
Name: cadherin 18
Synonyms: B230220E17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 320865
HGNC: HGNC:1757
Homologene: 55858
Gm7275
Name: predicted gene 7275
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 639644
VEGA: 16
Pfkm
Name: phosphofructokinase, muscle
Synonyms: PFK-A, Pfk4, PFK-M, Pfk-4, Pfkx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18642
VEGA: 15
HGNC: HGNC:8877
Homologene: 20101
Phactr2
Name: phosphatase and actin regulator 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215789
Homologene: 8816
Tubal3
Name: tubulin, alpha-like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238463
VEGA: 13
Homologene: 23488
Olfr1082
Name: olfactory receptor 1082
Synonyms: MOR192-4_p, GA_x6K02T2Q125-48079993-48079157
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 404473
Homologene: 104285
Rcor3
Name: REST corepressor 3
Synonyms: C730034D20Rik, 4921514E24Rik, E130101E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 214742
Homologene: 135671
Asb18
Name: ankyrin repeat and SOCS box-containing 18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 208372
Homologene: 16382
Mrps10
Name: mitochondrial ribosomal protein S10
Synonyms: Rpms10, 1110038B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 64657
Homologene: 10028
Marchf8
Name: membrane associated ring-CH-type finger 8
Synonyms: March8, Mir, 1300017E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71779
Homologene: 12412
Ubqln3
Name: ubiquilin 3
Synonyms: 4933400K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244178
Homologene: 9700
Lsamp
Name: limbic system-associated membrane protein
Synonyms: Lamp, B130007O04Rik, D930023J12Rik, Lam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268890
HGNC: HGNC:6705
Homologene: 20533
Samd13
Name: sterile alpha motif domain containing 13
Synonyms: LOC381481
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Dctn3
Name: dynactin 3
Synonyms: p24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 53598
HGNC: HGNC:2713
Homologene: 5233
Pcdha9
Name: protocadherin alpha 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 192161
HGNC: HGNC:8664
Homologene: 130700
Fam174a
Name: family with sequence similarity 174, member A
Synonyms: 2310044D20Rik, Tmem157
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 67698
Homologene: 12175
Gm9271
Name: predicted gene 9271
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 668618
Homologene: 45597
Ighv1-75
Name: immunoglobulin heavy variable 1-75
Synonyms: Gm16811
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 622728
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 89,954,462 bp
  • T to C, chromosome 1 at 95,314,247 bp
  • A to G, chromosome 1 at 127,551,330 bp
  • G to A, chromosome 1 at 127,822,966 bp
  • A to T, chromosome 1 at 181,828,902 bp
  • T to C, chromosome 1 at 192,120,130 bp
  • T to A, chromosome 2 at 86,594,001 bp
  • G to A, chromosome 2 at 120,046,484 bp
  • T to C, chromosome 2 at 131,179,014 bp
  • T to C, chromosome 3 at 90,275,626 bp
  • A to T, chromosome 3 at 102,947,829 bp
  • C to A, chromosome 3 at 146,646,310 bp
  • T to C, chromosome 4 at 41,716,407 bp
  • G to A, chromosome 4 at 126,745,047 bp
  • C to T, chromosome 4 at 141,389,317 bp
  • T to A, chromosome 5 at 34,870,806 bp
  • G to A, chromosome 5 at 54,109,733 bp
  • A to C, chromosome 6 at 116,403,520 bp
  • T to A, chromosome 7 at 10,170,934 bp
  • G to T, chromosome 7 at 39,363,652 bp
  • A to G, chromosome 7 at 58,803,675 bp
  • A to T, chromosome 7 at 103,979,714 bp
  • A to G, chromosome 7 at 104,142,433 bp
  • T to C, chromosome 7 at 143,692,947 bp
  • T to A, chromosome 9 at 105,397,835 bp
  • C to T, chromosome 9 at 106,474,505 bp
  • T to C, chromosome 9 at 106,651,076 bp
  • A to G, chromosome 10 at 13,474,065 bp
  • T to G, chromosome 10 at 58,465,667 bp
  • A to G, chromosome 10 at 74,635,672 bp
  • T to C, chromosome 10 at 106,951,990 bp
  • C to T, chromosome 11 at 9,277,891 bp
  • C to T, chromosome 11 at 70,917,529 bp
  • G to T, chromosome 11 at 83,004,721 bp
  • A to T, chromosome 11 at 120,656,345 bp
  • C to A, chromosome 12 at 115,834,254 bp
  • T to A, chromosome 13 at 3,933,432 bp
  • A to G, chromosome 15 at 23,226,768 bp
  • A to G, chromosome 15 at 27,902,748 bp
  • T to C, chromosome 15 at 38,030,657 bp
  • A to T, chromosome 15 at 71,622,016 bp
  • A to G, chromosome 15 at 76,174,532 bp
  • G to T, chromosome 15 at 81,360,774 bp
  • A to G, chromosome 15 at 98,122,226 bp
  • G to A, chromosome 15 at 100,585,993 bp
  • G to A, chromosome 15 at 101,947,609 bp
  • A to T, chromosome 16 at 29,220,410 bp
  • T to C, chromosome 16 at 42,134,423 bp
  • A to T, chromosome 16 at 48,074,164 bp
  • T to A, chromosome 17 at 47,378,242 bp
  • T to C, chromosome 18 at 12,498,936 bp
  • T to G, chromosome 18 at 36,998,816 bp
  • A to G, chromosome 18 at 62,505,971 bp
  • G to A, chromosome 19 at 24,750,401 bp
  • A to G, chromosome 19 at 29,812,463 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5617 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043276-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.