Strain Name:
C57BL/6J-MtgxR5631Btlr
Stock Number:
043282-MU
Citation ID:
RRID:MMRRC_043282-MU
Other Names:
R5631 (G1)
Major Collection:

Gene Information

Fn1
Name: fibronectin 1
Synonyms: Fn, Fn-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14268
HGNC: HGNC:3778
Homologene: 1533
Runx1
Name: runt related transcription factor 1
Synonyms: AML1, Cbfa2, Pebp2a2, runt domain, alpha subunit 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 12394
Homologene: 1331
Ldlrad3
Name: low density lipoprotein receptor class A domain containing 3
Synonyms: Lrad3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241576
Homologene: 18377
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: trithorax Drosophila, HTRX1, Cxxc7, Mll1, All1, Mll, ALL-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 214162
HGNC: HGNC:7132
Homologene: 4338
Anapc1
Name: anaphase promoting complex subunit 1
Synonyms: Mcpr, Apc1, 2610021O03Rik, tsg24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17222
Homologene: 7414
Yars
Name: tyrosyl-tRNA synthetase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 107271
Homologene: 2730
Heatr5a
Name: HEAT repeat containing 5A
Synonyms: D930036F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 320487
VEGA: 12
Homologene: 19635
Smc4
Name: structural maintenance of chromosomes 4
Synonyms: Smc4l1, 2500002A22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 70099
Homologene: 4015
Secisbp2l
Name: SECIS binding protein 2-like
Synonyms: 3110001I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 70354
Homologene: 18923
Rspry1
Name: ring finger and SPRY domain containing 1
Synonyms: 4930470D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 67610
Homologene: 12164
Cramp1l
Name: cramped chromatin regulator homolog 1
Synonyms: 5830477H08Rik, Tce4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 57354
VEGA: 17
Homologene: 35373
Clock
Name: circadian locomotor output cycles kaput
Synonyms: bHLHe8, 5330400M04Rik, KAT13D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12753
HGNC: HGNC:2082
Homologene: 3603
Stt3b
Name: STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
Synonyms: Simp, 1300006C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 68292
VEGA: 9
Homologene: 7387
Ap4m1
Name: adaptor-related protein complex AP-4, mu 1
Synonyms: 4930443L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 11781
HGNC: HGNC:574
Homologene: 3467
Adamtsl1
Name: ADAMTS-like 1
Synonyms: punctin-1, 5930437A14Rik, 6720426B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 77739
Homologene: 64642
Rplp2
Name: ribosomal protein, large P2
Synonyms: 2700049I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67186
Homologene: 133574
Fancm
Name: Fanconi anemia, complementation group M
Synonyms: C730036B14Rik, D12Ertd364e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 104806
VEGA: 12
Homologene: 35378
Thumpd1
Name: THUMP domain containing 1
Synonyms: 6330575P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233802
Homologene: 5878
Stag3
Name: stromal antigen 3
Synonyms: stromalin 3, SA-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 50878
Homologene: 40844
Kcnv1
Name: potassium channel, subfamily V, member 1
Synonyms: 2700023A03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 67498
VEGA: 15
Homologene: 22811
Tns2
Name: tensin 2
Synonyms: Tenc1, nph, nep
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 209039
VEGA: 15
Homologene: 37077
Slc9a5
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 5
Synonyms: LOC277973
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 277973
Homologene: 31247
Pkdrej
Name: polycystin (PKD) family receptor for egg jelly
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18766
VEGA: 15
HGNC: HGNC:9015
Homologene: 4427
Mrc1
Name: mannose receptor, C type 1
Synonyms: CD206, MR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17533
HGNC: HGNC:7228
Homologene: 37622
Hfm1
Name: HFM1, ATP-dependent DNA helicase homolog
Synonyms: Sec63d1, LOC381663, A330009G12Rik, Mer3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330149
Homologene: 87103
Dock3
Name: dedicator of cyto-kinesis 3
Synonyms: Moca, PBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 208869
HGNC: HGNC:2989
Homologene: 21030
Naip6
Name: NLR family, apoptosis inhibitory protein 6
Synonyms: Naip-rs4A, Naip-rs4, Birc1f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17952
HGNC: HGNC:7634
Homologene: 113589
Oplah
Name: 5-oxoprolinase (ATP-hydrolysing)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 75475
HGNC: HGNC:8149
Homologene: 90938
Zkscan3
Name: zinc finger with KRAB and SCAN domains 3
Synonyms: Zfp306, Zfp307, 2810435N07Rik, Skz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 72739
Homologene: 130732
Top2b
Name: topoisomerase (DNA) II beta
Synonyms: Top-2, D230016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 21974
Homologene: 134711
Ppfibp1
Name: PTPRF interacting protein, binding protein 1 (liprin beta 1)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67533
HGNC: HGNC:9249
Homologene: 2685
4933427D14Rik
Name: RIKEN cDNA 4933427D14 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 74477
Homologene: 8874
Trim34a
Name: tripartite motif-containing 34A
Synonyms: Trim34-1, Trim34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 94094
Homologene: 128238
Nrap
Name: nebulin-related anchoring protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18175
HGNC: HGNC:7988
Homologene: 4499
Hpx
Name: hemopexin
Synonyms: Hpxn, hx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 15458
HGNC: HGNC:5171
Homologene: 511
Ipo4
Name: importin 4
Synonyms: 8430408O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 75751
Homologene: 5835
Ccdc130
Name: coiled-coil domain containing 130
Synonyms: 4930527D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 67736
Homologene: 12183
Ccdc144b
Name: coiled-coil domain containing 144B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 241943
Homologene: 87263
Lrrc71
Name: leucine rich repeat containing 71
Synonyms: 4933430H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74485
Homologene: 83646
Ncoa5
Name: nuclear receptor coactivator 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228869
Homologene: 32496
Rps6ka4
Name: ribosomal protein S6 kinase, polypeptide 4
Synonyms: 1110069D02Rik, 90kDa, MSK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 56613
VEGA: 19
Homologene: 69288
Mfhas1
Name: malignant fibrous histiocytoma amplified sequence 1
Synonyms: D8Ertd91e, 2310066G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 52065
Homologene: 3114
Ugt3a2
Name: UDP glycosyltransferases 3 family, polypeptide A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223337
Homologene: 122787
Mrgprf
Name: MAS-related GPR, member F
Synonyms: MrgF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 211577
Homologene: 17023
Olfr1133
Name: olfactory receptor 1133
Synonyms: GA_x6K02T2Q125-49151278-49150337, MOR176-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258348
Smtnl1
Name: smoothelin-like 1
Synonyms: Chasm, 1110030K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68678
Homologene: 11488
Vmn1r128
Name: vomeronasal 1 receptor 128
Synonyms: Gm8509
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 667199
Homologene: 104166
Trp53i13
Name: transformation related protein 53 inducible protein 13
Synonyms: 2410019G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216964
Homologene: 16293
Mvb12b
Name: multivesicular body subunit 12B
Synonyms: Fam125b, 2610528K11Rik, 2610200O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 72543
Homologene: 25444
Polr3h
Name: polymerase (RNA) III (DNA directed) polypeptide H
Synonyms: 5031409G22Rik, RPC8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 78929
VEGA: 15
Homologene: 6337
Fam175a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 71,590,196 bp
  • A to T, chromosome 2 at 14,328,572 bp
  • G to T, chromosome 2 at 33,827,703 bp
  • T to C, chromosome 2 at 84,818,754 bp
  • A to T, chromosome 2 at 87,645,608 bp
  • T to C, chromosome 2 at 102,069,956 bp
  • C to T, chromosome 2 at 125,740,737 bp
  • T to C, chromosome 2 at 128,657,217 bp
  • T to C, chromosome 2 at 165,013,121 bp
  • G to C, chromosome 3 at 36,046,877 bp
  • T to C, chromosome 3 at 69,030,312 bp
  • T to A, chromosome 3 at 87,739,149 bp
  • C to T, chromosome 4 at 86,276,923 bp
  • T to G, chromosome 4 at 129,209,749 bp
  • G to A, chromosome 5 at 76,230,338 bp
  • T to G, chromosome 5 at 100,817,974 bp
  • A to G, chromosome 5 at 106,904,763 bp
  • A to G, chromosome 5 at 138,174,789 bp
  • T to A, chromosome 5 at 138,295,877 bp
  • T to C, chromosome 6 at 146,996,860 bp
  • G to A, chromosome 7 at 21,349,375 bp
  • A to T, chromosome 7 at 104,248,739 bp
  • A to T, chromosome 7 at 105,595,601 bp
  • A to G, chromosome 7 at 119,720,602 bp
  • A to C, chromosome 7 at 141,451,259 bp
  • A to G, chromosome 7 at 145,308,546 bp
  • G to A, chromosome 8 at 35,588,419 bp
  • G to T, chromosome 8 at 84,263,881 bp
  • A to T, chromosome 8 at 94,629,078 bp
  • C to T, chromosome 8 at 105,349,509 bp
  • A to T, chromosome 9 at 44,820,688 bp
  • T to C, chromosome 9 at 106,955,699 bp
  • G to A, chromosome 9 at 115,254,845 bp
  • C to A, chromosome 11 at 72,176,764 bp
  • C to A, chromosome 11 at 77,509,593 bp
  • T to A, chromosome 12 at 51,955,527 bp
  • T to C, chromosome 12 at 65,113,843 bp
  • A to G, chromosome 13 at 21,394,533 bp
  • T to C, chromosome 13 at 100,300,138 bp
  • T to C, chromosome 14 at 16,409,882 bp
  • A to G, chromosome 14 at 55,632,069 bp
  • C to T, chromosome 14 at 55,633,381 bp
  • T to C, chromosome 15 at 9,361,885 bp
  • T to A, chromosome 15 at 45,109,357 bp
  • T to C, chromosome 15 at 76,305,241 bp
  • T to A, chromosome 15 at 81,925,912 bp
  • T to C, chromosome 15 at 85,820,437 bp
  • C to T, chromosome 15 at 102,108,934 bp
  • C to A, chromosome 16 at 92,695,563 bp
  • T to A, chromosome 17 at 24,985,603 bp
  • T to C, chromosome 19 at 6,830,977 bp
  • T to G, chromosome 19 at 56,354,121 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5631 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043282-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.