Strain Name:
C57BL/6J-MtgxR5645Btlr
Stock Number:
043293-MU
Citation ID:
RRID:MMRRC_043293-MU
Other Names:
R5645 (G1)
Major Collection:

Gene Information

Dnmt1
Name: DNA methyltransferase (cytosine-5) 1
Synonyms: MTase, Cxxc9, MommeD2, Dnmt1o
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 13433
VEGA: 9
HGNC: HGNC:2976
Homologene: 124071
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, C130061D10Rik, Pam
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105689
Homologene: 9005
Ano6
Name: anoctamin 6
Synonyms: F730003B03Rik, 2900059G15Rik, Tmem16f
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 105722
VEGA: 15
Homologene: 27888
Fry
Name: FRY microtubule binding protein
Synonyms: 9330186A19Rik, cg003
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 320365
Homologene: 113770
Senp7
Name: SUMO1/sentrin specific peptidase 7
Synonyms: 2900036C23Rik, 6030449K19Rik, 2410152H17Rik, 2810413I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 66315
Homologene: 10778
Tacc2
Name: transforming, acidic coiled-coil containing protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 57752
Homologene: 5087
Sec16a
Name: SEC16 homolog A, endoplasmic reticulum export factor
Synonyms: C230052J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227648
Homologene: 10533
Ywhae
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
Synonyms: 14-3-3 epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 22627
Homologene: 100743
Tut4
Name: terminal uridylyl transferase 4
Synonyms: 6030404K05Rik, 9230115F04Rik, Zcchc11, Tent3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230594
Homologene: 35279
Akap9
Name: A kinase (PRKA) anchor protein (yotiao) 9
Synonyms: mei2-5, G1-448-15, 5730481H23Rik, AKAP450, repro12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Akap1
Name: A kinase (PRKA) anchor protein 1
Synonyms: S-AKAP84, DAKAP1, AKAP84, AKAP121
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11640
HGNC: HGNC:367
Homologene: 31165
Sdha
Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Synonyms: FP, SDHF, SDH2, 2310034D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66945
Homologene: 3073
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: Murr2, A530081C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17847
Homologene: 40978
Elp1
Name: elongator complex protein 1
Synonyms: C78473, 3110040G09Rik, IKAP, Ikbkap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230233
HGNC: HGNC:5959
Homologene: 2699
Cul5
Name: cullin 5
Synonyms: VACM-1, C330021I08Rik, 4921514I20Rik, 8430423K24Rik, C030032G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 75717
HGNC: HGNC:2556
Homologene: 2597
Klf13
Name: Kruppel-like factor 13
Synonyms: FKLF-2, RFLAT1, RFLAT-1, 9430029L20Rik, NSLP1, Bteb3, Klf13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 50794
Homologene: 32288
Iqgap3
Name: IQ motif containing GTPase activating protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 404710
Homologene: 26400
Pfas
Name: phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
Synonyms: Sofa, 4432409B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237823
HGNC: HGNC:8863
Homologene: 5970
Hpf1
Name: histone PARylation factor 1
Synonyms: 2700029M09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 72612
Homologene: 32374
Ifnar2
Name: interferon (alpha and beta) receptor 2
Synonyms: Ifnar-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 15976
HGNC: HGNC:5433
Homologene: 49242
Leng8
Name: leukocyte receptor cluster (LRC) member 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232798
Homologene: 13612
Adamts12
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239337
VEGA: 15
Homologene: 12808
Boc
Name: biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 117606
Homologene: 32819
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Oser1
Name: oxidative stress responsive serine rich 1
Synonyms: 3230401D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 66680
Homologene: 9521
Cep295
Name: centrosomal protein 295
Synonyms: LOC382128, 5830418K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 319675
Homologene: 27936
Itgae
Name: integrin alpha E, epithelial-associated
Synonyms: alpha-E1, CD103
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16407
HGNC: HGNC:6147
Homologene: 113560
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 665700
Homologene: 90772
Mslnl
Name: mesothelin-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 328783
VEGA: 17
Homologene: 18633
Nkx2-2
Name: NK2 homeobox 2
Synonyms: Nkx-2.2, Nkx2.2, tinman
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18088
HGNC: HGNC:7835
Homologene: 1879
Rusc2
Name: RUN and SH3 domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 100213
Homologene: 18967
Slc9a5
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 5
Synonyms: LOC277973
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 277973
Homologene: 31247
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225997
VEGA: 19
Homologene: 9767
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: PKHDL1, fibrocystin L, D86 mRNA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 192190
Homologene: 16332
Mab21l4
Name: mab-21-like 4
Synonyms: 2310007B03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 71874
Homologene: 11761
Trim80
Name: tripartite motif-containing 80
Synonyms: 4933422H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 432613
Homologene: 46325
5830411N06Rik
Name: RIKEN cDNA 5830411N06 gene
Synonyms: Scart2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244234
Homologene: 133218
Acsm1
Name: acyl-CoA synthetase medium-chain family member 1
Synonyms: Macs, Bucs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 117147
Homologene: 24930
Prph2
Name: peripherin 2
Synonyms: rds, Rd2, Tspan22, Nmf193
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 19133
HGNC: HGNC:9942
Homologene: 273
Treh
Name: trehalase (brush-border membrane glycoprotein)
Synonyms: 2210412M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 58866
Homologene: 5198
Adcy2
Name: adenylate cyclase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 210044
VEGA: 13
HGNC: HGNC:233
Homologene: 75133
Fam214a
Name: family with sequence similarity 214, member A
Synonyms: C130047D21Rik, BC031353, 6330415I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235493
VEGA: 9
Homologene: 35065
Grin2a
Name: glutamate receptor, ionotropic, NMDA2A (epsilon 1)
Synonyms: GluN2A, NMDAR2A, GluRepsilon1, NR2A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 14811
HGNC: HGNC:4585
Homologene: 645
Slco1a4
Name: solute carrier organic anion transporter family, member 1a4
Synonyms: Oatp1a4, Oatp2, Slc21a5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 28250
Homologene: 130782
Kansl1l
Name: KAT8 regulatory NSL complex subunit 1-like
Synonyms: 1110028C15Rik, C430010P07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68691
Homologene: 27376
Abca6
Name: ATP-binding cassette, sub-family A (ABC1), member 6
Synonyms: 6330565N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 76184
HGNC: HGNC:36
Homologene: 71264
Heg1
Name: heart development protein with EGF-like domains 1
Synonyms: 9530025L16Rik, 5530401I02Rik, 4632417D23Rik, LOC268884
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 77446
Homologene: 35276
Gm1123
Name: predicted gene 1123
Synonyms: LOC382097
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 382097
Homologene: 135699
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: Mll2, Mll4, C430014K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Cyp2c37
Name: cytochrome P450, family 2. subfamily c, polypeptide 37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 13096
Homologene: 137231
Iqcc
Name: IQ motif containing C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230767
Homologene: 49526
Asap2
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
Synonyms: LOC385250, 6530401G17Rik, Ddef2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 211914
HGNC: HGNC:2721
Homologene: 2888
Amer3
Name: APC membrane recruitment 3
Synonyms: 9430069J07Rik, Fam123c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 211383
Homologene: 51888
4930503B20Rik
Name: RIKEN cDNA 4930503B20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 75015
Homologene: 41344
Sncaip
Name: synuclein, alpha interacting protein (synphilin)
Synonyms: 4933427B05Rik, synphilin-1, SYPH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 67847
Homologene: 3987
Kbtbd3
Name: kelch repeat and BTB (POZ) domain containing 3
Synonyms: 2200003A07Rik, Bklhd3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 69149
Homologene: 12300
Agbl4
Name: ATP/GTP binding protein-like 4
Synonyms: Ccp6, 4930578N11Rik, 4931433A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 78933
Homologene: 84880
Car13
Name: carbonic anhydrase 13
Synonyms: 2310075C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71934
Homologene: 75207
Cr2
Name: complement receptor 2
Synonyms: Cr1, CD21, Cr-1, CD35, Cr-2, C3DR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12902
HGNC: HGNC:2336
Homologene: 55611
Apba2
Name: amyloid beta (A4) precursor protein-binding, family A, member 2
Synonyms: X11-like, Mint 2, X11L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11784
HGNC: HGNC:579
Homologene: 4021
Olfr1233
Name: olfactory receptor 1233
Synonyms: GA_x6K02T2Q125-50784973-50784056, MOR238-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258974
Homologene: 74243
Skint1
Name: selection and upkeep of intraepithelial T cells 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 639781
Homologene: 87538
Olfr745
Name: olfactory receptor 745
Synonyms: MOR106-11, GA_x6K02T2PMLR-6361495-6362481
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258296
Homologene: 27116
Tekt1
Name: tektin 1
Synonyms: MT14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 21689
Homologene: 7973
Glb1l3
Name: galactosidase, beta 1 like 3
Synonyms: 4921509F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 70893
Homologene: 72240
Fam161a
Name: family with sequence similarity 161, member A
Synonyms: 4930430E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 73873
Homologene: 19131
Tjp3
Name: tight junction protein 3
Synonyms: ZO-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 27375
VEGA: 10
Homologene: 8458
Vps9d1
Name: VPS9 domain containing 1
Synonyms: 1300018I17Rik, 2410004N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 72325
Homologene: 21021
Ak5
Name: adenylate kinase 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229949
HGNC: HGNC:365
Homologene: 76103
1700102P08Rik
Name: RIKEN cDNA 1700102P08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 112418
Homologene: 14230
4930549C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
Gm29096
Name: predicted gene 29096
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 34,588,381 bp
  • T to C, chromosome 1 at 66,801,344 bp
  • T to C, chromosome 1 at 93,152,946 bp
  • G to T, chromosome 1 at 195,154,273 bp
  • T to G, chromosome 2 at 26,439,895 bp
  • C to A, chromosome 2 at 31,420,812 bp
  • A to T, chromosome 2 at 89,339,705 bp
  • T to C, chromosome 2 at 147,184,399 bp
  • C to T, chromosome 2 at 163,407,045 bp
  • T to A, chromosome 3 at 14,645,120 bp
  • T to C, chromosome 3 at 88,117,699 bp
  • C to T, chromosome 3 at 146,650,509 bp
  • A to T, chromosome 3 at 152,656,033 bp
  • G to T, chromosome 4 at 43,425,758 bp
  • T to C, chromosome 4 at 56,776,920 bp
  • G to A, chromosome 4 at 108,557,373 bp
  • A to T, chromosome 4 at 111,657,330 bp
  • A to G, chromosome 4 at 112,025,502 bp
  • A to T, chromosome 4 at 129,616,527 bp
  • G to T, chromosome 4 at 136,612,917 bp
  • A to G, chromosome 5 at 4,050,590 bp
  • T to C, chromosome 5 at 150,380,867 bp
  • T to C, chromosome 6 at 141,834,659 bp
  • A to G, chromosome 7 at 4,145,274 bp
  • G to A, chromosome 7 at 63,891,600 bp
  • A to G, chromosome 7 at 64,695,806 bp
  • A to G, chromosome 7 at 119,640,697 bp
  • A to T, chromosome 7 at 130,624,051 bp
  • G to A, chromosome 7 at 140,248,940 bp
  • T to G, chromosome 8 at 60,896,800 bp
  • T to C, chromosome 8 at 105,357,013 bp
  • A to G, chromosome 8 at 123,247,748 bp
  • A to G, chromosome 9 at 4,331,426 bp
  • A to T, chromosome 9 at 15,332,794 bp
  • C to A, chromosome 9 at 15,335,108 bp
  • G to A, chromosome 9 at 20,922,147 bp
  • G to T, chromosome 9 at 26,824,826 bp
  • A to G, chromosome 9 at 44,682,678 bp
  • T to C, chromosome 9 at 53,622,943 bp
  • T to A, chromosome 9 at 75,025,679 bp
  • T to C, chromosome 9 at 99,014,191 bp
  • A to G, chromosome 9 at 108,397,204 bp
  • T to C, chromosome 10 at 41,552,356 bp
  • T to C, chromosome 10 at 81,278,620 bp
  • T to A, chromosome 11 at 23,015,725 bp
  • T to C, chromosome 11 at 23,375,024 bp
  • A to G, chromosome 11 at 68,991,132 bp
  • A to T, chromosome 11 at 72,351,837 bp
  • A to G, chromosome 11 at 73,129,248 bp
  • T to C, chromosome 11 at 75,756,924 bp
  • T to C, chromosome 11 at 88,845,627 bp
  • T to C, chromosome 11 at 110,250,408 bp
  • T to A, chromosome 11 at 115,446,785 bp
  • T to A, chromosome 12 at 21,265,982 bp
  • C to A, chromosome 13 at 68,729,202 bp
  • A to G, chromosome 13 at 74,323,839 bp
  • T to C, chromosome 14 at 50,643,067 bp
  • A to T, chromosome 14 at 103,188,608 bp
  • C to A, chromosome 14 at 103,188,615 bp
  • A to G, chromosome 15 at 11,277,420 bp
  • A to G, chromosome 15 at 44,532,992 bp
  • A to G, chromosome 15 at 95,920,351 bp
  • A to G, chromosome 15 at 98,844,397 bp
  • T to A, chromosome 16 at 9,992,226 bp
  • A to G, chromosome 16 at 33,706,963 bp
  • A to G, chromosome 16 at 44,499,661 bp
  • T to A, chromosome 16 at 56,173,208 bp
  • A to G, chromosome 16 at 91,404,227 bp
  • G to T, chromosome 17 at 25,737,842 bp
  • G to T, chromosome 17 at 46,910,667 bp
  • A to G, chromosome 17 at 67,802,948 bp
  • A to G, chromosome 18 at 52,894,956 bp
  • A to G, chromosome 19 at 18,853,604 bp
  • G to A, chromosome 19 at 39,994,152 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5645 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043293-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.