Strain Name:
C57BL/6J-MtgxR5651Btlr
Stock Number:
043297-MU
Citation ID:
RRID:MMRRC_043297-MU
Other Names:
R5651 (G1)
Major Collection:

Gene Information

Pkd1
Name: polycystin 1, transient receptor potential channel interacting
Synonyms: polycystin-1, PC1, PC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 18763
VEGA: 17
HGNC: HGNC:9008
Homologene: 250
Htr2a
Name: 5-hydroxytryptamine (serotonin) receptor 2A
Synonyms: 5-HT2A receptor, Htr-2, Htr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 15558
VEGA: 14
HGNC: HGNC:5293
Homologene: 68073
Hnrnpa1
Name: heterogeneous nuclear ribonucleoprotein A1
Synonyms: hnrnp-A, Hdp, D15Ertd119e, Hnrpa1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 15382
VEGA: 15
HGNC: HGNC:5031
Homologene: 134628
Rxra
Name: retinoid X receptor alpha
Synonyms: RXRalpha1, RXR alpha 1, 9530071D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20181
Homologene: 2220
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Pam, C130061D10Rik, Phr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105689
Homologene: 9005
Plk4
Name: polo like kinase 4
Synonyms: Sak, Stk18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20873
Homologene: 7962
Tanc2
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Synonyms: 5730590C14Rik, 3526402J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 77097
Homologene: 64680
Senp1
Name: SUMO1/sentrin specific peptidase 1
Synonyms: 2310046A20Rik, E330036L07Rik, D15Ertd528e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223870
Homologene: 8731
Phldb1
Name: pleckstrin homology like domain, family B, member 1
Synonyms: LL5A, D330037A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102693
Homologene: 15903
Cald1
Name: caldesmon 1
Synonyms: 4833423D12Rik, C920027I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 109624
HGNC: HGNC:1441
Homologene: 137254
Rasal2
Name: RAS protein activator like 2
Synonyms: A330066M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226525
HGNC: HGNC:9874
Homologene: 35217
Cftr
Name: cystic fibrosis transmembrane conductance regulator
Synonyms: Abcc7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12638
HGNC: HGNC:1884
Homologene: 55465
Ier5
Name: immediate early response 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 15939
HGNC: HGNC:5393
Homologene: 7778
Slc49a4
Name: solute carrier family 49 member 4
Synonyms: RCC4, Dirc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224132
Homologene: 13137
Cecr2
Name: CECR2, histone acetyl-lysine reader
Synonyms: 2810409N01Rik, 2610101O16Rik, Gtl4, cat eye syndrome chromosome region, candidate 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330409
HGNC: HGNC:1840
Homologene: 64662
Xpot
Name: exportin, tRNA (nuclear export receptor for tRNAs)
Synonyms: EXPORTIN-T, C79645, 1110004L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 73192
VEGA: 10
Homologene: 38291
Boc
Name: biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 117606
Homologene: 32819
Mia3
Name: melanoma inhibitory activity 3
Synonyms: LOC385255, Tango, A930039G15Rik, B230399H06Rik, 9130229H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 338366
Homologene: 85165
Palld
Name: palladin, cytoskeletal associated protein
Synonyms: 2410003B16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72333
Homologene: 75052
Mpp7
Name: membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
Synonyms: 5430426E14Rik, 2810038M04Rik, LOC381166, 1110068J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 75739
VEGA: 18
Homologene: 1455
Inka2
Name: inka box actin regulator 2
Synonyms: 6530418L21Rik, Inka2, Fam212b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 109050
Homologene: 10421
Atp8b1
Name: ATPase, class I, type 8B, member 1
Synonyms: FIC1, Ic
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 54670
VEGA: 18
HGNC: HGNC:3706
Homologene: 21151
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: tigmin, FPC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Sh3rf1
Name: SH3 domain containing ring finger 1
Synonyms: Posh, 2200003J05Rik, Sh3md2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 59009
Homologene: 10988
Brinp3
Name: bone morphogenetic protein/retinoic acid inducible neural specific 3
Synonyms: B830045N13Rik, Fam5c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 215378
Homologene: 17786
Atp11b
Name: ATPase, class VI, type 11B
Synonyms: 1110019I14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 76295
Homologene: 32919
Taok2
Name: TAO kinase 2
Synonyms: MAP3K17, TAO2, TAO1, PSK1, 1110033K02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381921
Homologene: 74531
Fshr
Name: follicle stimulating hormone receptor
Synonyms: follicle-stimulating hormone receptor, Follitropin receptor, FSH-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 14309
VEGA: 17
HGNC: HGNC:3969
Homologene: 117
Pappa
Name: pregnancy-associated plasma protein A
Synonyms: PAG1, IGFBP-4ase, PAPP-A, 8430414N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 18491
HGNC: HGNC:8602
Homologene: 31097
Thsd7a
Name: thrombospondin, type I, domain containing 7A
Synonyms: LOC330267
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330267
Homologene: 46582
Olfr70
Name: olfactory receptor 70
Synonyms: mOR6, MOR262-10, GA_x6K02T2N78B-16239704-16240654
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 56014
Homologene: 10459
Mmut
Name: methylmalonyl-Coenzyme A mutase
Synonyms: D230010K02Rik, Mut
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17850
VEGA: 17
HGNC: HGNC:7526
Homologene: 20097
Olfr177
Name: olfactory receptor 177
Synonyms: GA_x54KRFPKG5P-55091371-55090442, MOR184-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258998
Homologene: 121500
AY358078
Name: cDNA sequence AY358078
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 278676
Homologene: 115686
Krt87
Name: keratin 87
Synonyms: Krt2-25, Krt83
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 406219
VEGA: 15
Homologene: 133804
Fbxo11
Name: F-box protein 11
Synonyms: GENA 104, Jf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225055
Homologene: 11843
Vmn1r215
Name: vomeronasal 1 receptor 215
Synonyms: V1ri2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 171253
Homologene: 110880
Vcpip1
Name: valosin containing protein (p97)/p47 complex interacting protein 1
Synonyms: 5730421J18Rik, 5730538E15Rik, Vcip135
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 70675
Homologene: 11814
Mast1
Name: microtubule associated serine/threonine kinase 1
Synonyms: 9430008B02Rik, SAST170, SAST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 56527
Homologene: 10543
Hhla1
Name: HERV-H LTR-associating 1
Synonyms: F930104E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 654498
HGNC: HGNC:4904
Homologene: 129987
V1ra8
Name: vomeronasal 1 receptor, A8
Synonyms: Vmn1r-ps33
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 113850
Vmn1r233
Name: vomeronasal 1 receptor 233
Synonyms: V1rf5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 171236
Homologene: 128343
Cyp2c38
Name: cytochrome P450, family 2, subfamily c, polypeptide 38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 13097
HGNC: HGNC:2622
Homologene: 117948
Slfn5
Name: schlafen 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 327978
Homologene: 18839
Olfr1053
Name: olfactory receptor 1053
Synonyms: GA_x6K02T2Q125-47793414-47792471, MOR187-4, Olfr1053-ps1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257974
Homologene: 74197
Olfr311
Name: olfactory receptor 311
Synonyms: GA_x6K02T2NKPP-565870-564944, MOR222-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258530
Homologene: 77375
9930111J21Rik2
Name: RIKEN cDNA 9930111J21 gene 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 245240
B020004C17Rik
Name: RIKEN cDNA B020004C17 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 432860
VEGA: 14
Homologene: 128423
Psmb5
Name: proteasome (prosome, macropain) subunit, beta type 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19173
VEGA: 14
HGNC: HGNC:9542
Homologene: 55690
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 9,747,840 bp
  • C to T, chromosome 1 at 20,117,807 bp
  • A to T, chromosome 1 at 146,701,799 bp
  • T to C, chromosome 1 at 155,098,745 bp
  • A to G, chromosome 1 at 157,157,381 bp
  • T to A, chromosome 1 at 183,358,654 bp
  • C to T, chromosome 2 at 27,737,341 bp
  • A to G, chromosome 2 at 86,314,440 bp
  • A to G, chromosome 3 at 35,855,140 bp
  • A to G, chromosome 3 at 40,813,505 bp
  • C to A, chromosome 3 at 105,716,432 bp
  • C to G, chromosome 4 at 43,696,636 bp
  • A to G, chromosome 4 at 65,156,352 bp
  • C to T, chromosome 6 at 12,343,213 bp
  • T to A, chromosome 6 at 18,255,365 bp
  • T to A, chromosome 6 at 34,762,320 bp
  • T to C, chromosome 6 at 90,203,526 bp
  • G to A, chromosome 6 at 120,755,560 bp
  • T to C, chromosome 7 at 126,880,283 bp
  • A to G, chromosome 8 at 61,363,167 bp
  • A to T, chromosome 8 at 61,538,788 bp
  • G to C, chromosome 8 at 84,928,968 bp
  • G to A, chromosome 9 at 44,711,903 bp
  • A to T, chromosome 10 at 121,604,549 bp
  • G to A, chromosome 11 at 49,019,873 bp
  • A to T, chromosome 11 at 58,841,491 bp
  • A to C, chromosome 11 at 82,960,664 bp
  • T to A, chromosome 11 at 105,798,700 bp
  • T to G, chromosome 13 at 23,075,811 bp
  • T to A, chromosome 14 at 51,822,160 bp
  • C to T, chromosome 14 at 54,616,764 bp
  • C to T, chromosome 14 at 57,015,232 bp
  • T to A, chromosome 14 at 74,705,703 bp
  • A to G, chromosome 14 at 103,282,665 bp
  • T to A, chromosome 15 at 65,941,814 bp
  • A to G, chromosome 15 at 98,076,617 bp
  • A to T, chromosome 15 at 101,434,029 bp
  • G to C, chromosome 15 at 103,240,528 bp
  • G to A, chromosome 16 at 35,735,616 bp
  • T to A, chromosome 16 at 44,521,195 bp
  • A to G, chromosome 16 at 58,872,484 bp
  • T to A, chromosome 17 at 20,994,017 bp
  • A to G, chromosome 17 at 24,591,387 bp
  • T to A, chromosome 17 at 40,947,111 bp
  • A to T, chromosome 17 at 88,015,708 bp
  • T to A, chromosome 17 at 88,985,829 bp
  • A to G, chromosome 18 at 7,355,016 bp
  • G to C, chromosome 18 at 64,531,382 bp
  • T to A, chromosome 19 at 39,460,712 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5651 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043297-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.