Strain Name:
C57BL/6J-MtgxR5659Btlr
Stock Number:
043303-MU
Citation ID:
RRID:MMRRC_043303-MU
Other Names:
R5659 (G1)
Major Collection:

Gene Information

Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Olr1
Name: oxidized low density lipoprotein (lectin-like) receptor 1
Synonyms: LOX-1, Scare1, SR-EI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 108078
HGNC: HGNC:8133
Homologene: 1910
Kmt2e
Name: lysine (K)-specific methyltransferase 2E
Synonyms: 1810033J14Rik, D230038D11Rik, 9530077A04Rik, Mll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 69188
Homologene: 18822
Ppp1r37
Name: protein phosphatase 1, regulatory subunit 37
Synonyms: Lrrc68
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232947
Homologene: 17851
Usp32
Name: ubiquitin specific peptidase 32
Synonyms: 6430526O11Rik, 2900074J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237898
Homologene: 13066
Zfat
Name: zinc finger and AT hook domain containing
Synonyms: LOC380993, Zfp406, Zfat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 380993
Homologene: 16829
Luzp1
Name: leucine zipper protein 1
Synonyms: Luzp, 2700072H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269593
Homologene: 11545
Dhx9
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 9
Synonyms: leukophysin, nuclear DNA helicase II, RNA helicase, Ddx9, NDH II, NDHII, RHA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 13211
HGNC: HGNC:2750
Homologene: 1039
Brd1
Name: bromodomain containing 1
Synonyms: 1110059H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223770
HGNC: HGNC:1102
Homologene: 40956
Arhgap32
Name: Rho GTPase activating protein 32
Synonyms: p200RhoGAP, GC-GAP, PX-RICS, 3426406O18Rik, Grit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 330914
Homologene: 8812
Apaf1
Name: apoptotic peptidase activating factor 1
Synonyms: Apaf1l, 6230400I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11783
HGNC: HGNC:576
Homologene: 7626
Cyb5r4
Name: cytochrome b5 reductase 4
Synonyms: B5+B5R, b5/b5r, 2810034J18Rik, Ncb5or
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 266690
Homologene: 69207
Bcl6
Name: B cell leukemia/lymphoma 6
Synonyms: Bcl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12053
HGNC: HGNC:1001
Homologene: 7640
Rhot1
Name: ras homolog family member T1
Synonyms: Miro1, 2210403N23Rik, FLJ11040, Arht1, C430039G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 59040
Homologene: 56803
Sv2a
Name: synaptic vesicle glycoprotein 2 a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 64051
Homologene: 32237
Lpin1
Name: lipin 1
Synonyms: Lipin1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 14245
VEGA: 12
Homologene: 9266
Gin1
Name: gypsy retrotransposon integrase 1
Synonyms: 4930429M06, 4930429M06Rik, Zh2c2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 252876
Homologene: 69238
Kat6a
Name: K(lysine) acetyltransferase 6A
Synonyms: MOZ, Zfp220, 9930021N24Rik, Myst3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244349
Homologene: 4924
Phf21b
Name: PHD finger protein 21B
Synonyms: A730032D07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 271305
Homologene: 78154
Klhl20
Name: kelch-like 20
Synonyms: D930050H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226541
Homologene: 8699
Gipc1
Name: GIPC PDZ domain containing family, member 1
Synonyms: synectin, TIP-2, Semcap1, neurophilin1-IP, Glut1CIP, TaxIP2, Rgs19ip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 67903
HGNC: HGNC:1226
Homologene: 21167
Tspan11
Name: tetraspanin 11
Synonyms: 1110014F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 68498
Homologene: 23595
Pcdhac1
Name: protocadherin alpha subfamily C, 1
Synonyms: CNRc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 353236
HGNC: HGNC:8676
Homologene: 49561
Zfp637
Name: zinc finger protein 637
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232337
Homologene: 5069
Slc5a8
Name: solute carrier family 5 (iodide transporter), member 8
Synonyms: SMCT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216225
VEGA: 10
Homologene: 64832
Zhx2
Name: zinc fingers and homeoboxes 2
Synonyms: Raf, Afr-1, Afr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 387609
Homologene: 8968
Aqp8
Name: aquaporin 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11833
HGNC: HGNC:642
Homologene: 68166
Ap3b2
Name: adaptor-related protein complex 3, beta 2 subunit
Synonyms: Naptb, beta3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11775
HGNC: HGNC:567
Homologene: 55837
Zbtb38
Name: zinc finger and BTB domain containing 38
Synonyms: A930014K01Rik, Zenon homolog, CIBZ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245007
Homologene: 19529
Ros1
Name: Ros1 proto-oncogene
Synonyms: Ros-1, c-ros
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19886
Homologene: 2207
Ankhd1
Name: ankyrin repeat and KH domain containing 1
Synonyms: 1110004O12Rik, 9130019P20Rik, 4933432B13Rik, A530027J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 108857
Homologene: 87006
Atp10b
Name: ATPase, class V, type 10B
Synonyms: 5930426O13Rik, 9030605H24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 319767
Homologene: 70969
Pam
Name: peptidylglycine alpha-amidating monooxygenase
Synonyms: PHM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18484
HGNC: HGNC:8596
Homologene: 37369
Dnah7b
Name: dynein, axonemal, heavy chain 7B
Synonyms: LOC227058, Dnahc7b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227058
Homologene: 41287
Pld2
Name: phospholipase D2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18806
HGNC: HGNC:9068
Homologene: 55672
Zfp788
Name: zinc finger protein 788
Synonyms: 2810426N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 67607
Homologene: 137363
Ano5
Name: anoctamin 5
Synonyms: Gdd1, Tmem16e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233246
Homologene: 100071
Rasgrf1
Name: RAS protein-specific guanine nucleotide-releasing factor 1
Synonyms: CDC25Mm, Grfbeta, CDC25, Grf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19417
HGNC: HGNC:9875
Homologene: 74972
Olfr267
Name: olfactory receptor 267
Synonyms: GA_x6K02T2N78B-1272842-1273783, MOR262-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 258922
HGNC: HGNC:8264
Homologene: 17436
Cxcr5
Name: chemokine (C-X-C motif) receptor 5
Synonyms: Gpcr6, CXCR-5, Blr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12145
VEGA: 9
HGNC: HGNC:1060
Homologene: 1298
Cyp3a25
Name: cytochrome P450, family 3, subfamily a, polypeptide 25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56388
Homologene: 135775
Rmnd1
Name: required for meiotic nuclear division 1 homolog
Synonyms: 0610042C05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 66084
Homologene: 5675
Shc3
Name: src homology 2 domain-containing transforming protein C3
Synonyms: ShcC, N-Shc, Rai
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 20418
VEGA: 13
Homologene: 7536
Olfr3
Name: olfactory receptor 3
Synonyms: Y71, MOR136-14, GA_x6K02T2NLDC-33507606-33506665
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 18328
HGNC: HGNC:8208
Homologene: 66579
Cblc
Name: Casitas B-lineage lymphoma c
Synonyms: Cbl3, 2310079L19Rik, 2310076I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 80794
Homologene: 8108
Brsk1
Name: BR serine/threonine kinase 1
Synonyms: LOC381979, SAD-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381979
Homologene: 57169
Slc25a23
Name: solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
Synonyms: 2310067G05Rik, SCaMC-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 66972
Homologene: 11467
Ccdc87
Name: coiled-coil domain containing 87
Synonyms: 4931419P11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 399599
VEGA: 19
Homologene: 49531
Olfr922
Name: olfactory receptor 922
Synonyms: GA_x6K02T2PVTD-32518237-32519172, MOR161-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258777
VEGA: 9
Homologene: 27262
Scgb1b10
Name: secretoglobin, family 1B, member 10
Synonyms: Gm4384, Abpa10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 102635992
Homologene: 114479
Sqrdl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Fam179a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 46,352,849 bp
  • A to G, chromosome 1 at 97,775,532 bp
  • T to C, chromosome 1 at 97,842,299 bp
  • A to G, chromosome 1 at 153,471,735 bp
  • A to G, chromosome 1 at 161,090,470 bp
  • A to T, chromosome 2 at 36,812,954 bp
  • G to A, chromosome 2 at 122,787,603 bp
  • G to C, chromosome 3 at 96,190,303 bp
  • A to T, chromosome 4 at 58,785,672 bp
  • T to A, chromosome 4 at 136,542,476 bp
  • T to C, chromosome 5 at 23,497,807 bp
  • T to C, chromosome 5 at 145,991,546 bp
  • G to A, chromosome 6 at 117,843,330 bp
  • T to A, chromosome 6 at 127,938,277 bp
  • T to A, chromosome 6 at 129,500,029 bp
  • C to T, chromosome 7 at 4,715,372 bp
  • C to T, chromosome 7 at 19,535,523 bp
  • A to G, chromosome 7 at 19,792,932 bp
  • G to T, chromosome 7 at 32,100,878 bp
  • T to A, chromosome 7 at 41,650,116 bp
  • G to A, chromosome 7 at 51,583,814 bp
  • T to A, chromosome 7 at 81,476,752 bp
  • G to A, chromosome 7 at 123,466,666 bp
  • T to A, chromosome 8 at 22,938,160 bp
  • A to T, chromosome 8 at 83,664,126 bp
  • T to A, chromosome 9 at 32,181,960 bp
  • C to T, chromosome 9 at 38,815,776 bp
  • C to T, chromosome 9 at 44,513,393 bp
  • T to A, chromosome 9 at 87,055,828 bp
  • T to A, chromosome 9 at 89,984,289 bp
  • T to C, chromosome 9 at 96,687,420 bp
  • A to T, chromosome 10 at 4,427,382 bp
  • G to A, chromosome 10 at 52,143,386 bp
  • C to T, chromosome 10 at 88,919,428 bp
  • A to T, chromosome 10 at 91,062,153 bp
  • T to A, chromosome 11 at 43,245,425 bp
  • T to C, chromosome 11 at 70,557,561 bp
  • T to G, chromosome 11 at 80,250,355 bp
  • A to G, chromosome 11 at 85,077,414 bp
  • A to T, chromosome 12 at 16,540,989 bp
  • C to A, chromosome 13 at 13,634,627 bp
  • T to C, chromosome 13 at 51,516,594 bp
  • T to C, chromosome 15 at 57,822,308 bp
  • T to C, chromosome 15 at 68,119,013 bp
  • C to T, chromosome 15 at 84,793,900 bp
  • T to C, chromosome 15 at 88,713,381 bp
  • A to T, chromosome 16 at 23,968,409 bp
  • A to G, chromosome 17 at 57,045,500 bp
  • G to T, chromosome 17 at 71,687,672 bp
  • T to C, chromosome 18 at 36,561,050 bp
  • T to C, chromosome 18 at 37,092,417 bp
  • T to C, chromosome 19 at 4,840,850 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5659 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043303-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.