Strain Name:
C57BL/6J-MtgxR5671Btlr
Stock Number:
043314-MU
Citation ID:
RRID:MMRRC_043314-MU
Other Names:
R5671 (G1)
Major Collection:

Gene Information

Zfp423
Name: zinc finger protein 423
Synonyms: ataxia1, Roaz, Ebfaz, Zfp104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 94187
Homologene: 9010
Ak2
Name: adenylate kinase 2
Synonyms: Ak-2, D4Ertd220e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11637
HGNC: HGNC:362
Homologene: 1227
Washc4
Name: WASH complex subunit 4
Synonyms: A230046K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 319277
VEGA: 10
Homologene: 123926
Flnb
Name: filamin, beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 286940
HGNC: HGNC:3755
Homologene: 37480
Gpa33
Name: glycoprotein A33 (transmembrane)
Synonyms: A33 antigen, 2210401D16Rik, 2010310L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 59290
HGNC: HGNC:4445
Homologene: 4245
Ap3b1
Name: adaptor-related protein complex 3, beta 1 subunit
Synonyms: AP-3, beta3A, rim2, Hps2, recombination induced mutation 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 11774
VEGA: 13
HGNC: HGNC:566
Homologene: 68125
Cdx1
Name: caudal type homeobox 1
Synonyms: Cdx, Cdx-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 12590
HGNC: HGNC:1805
Homologene: 1366
Akap8l
Name: A kinase (PRKA) anchor protein 8-like
Synonyms: Nakap95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 54194
VEGA: 17
Homologene: 8658
Lmbr1l
Name: limb region 1 like
Synonyms: 1110013E13Rik, D15Ertd735e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 74775
Homologene: 10011
Rnd2
Name: Rho family GTPase 2
Synonyms: Rohn, Arhn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11858
Homologene: 21123
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 236266
HGNC: HGNC:428
Homologene: 49406
Kank4
Name: KN motif and ankyrin repeat domains 4
Synonyms: Ankrd38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242553
Homologene: 18244
Clca4b
Name: chloride channel accessory 4B
Synonyms: AI747448
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99709
HGNC: HGNC:2018
Homologene: 40808
Clec14a
Name: C-type lectin domain family 14, member a
Synonyms: 1200003C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 66864
VEGA: 12
Homologene: 12047
Vps51
Name: VPS51 GARP complex subunit
Synonyms: 1110014N23Rik, 3110057M17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 68505
HGNC: HGNC:1172
Homologene: 34675
2700049A03Rik
Name: RIKEN cDNA 2700049A03 gene
Synonyms: talpid3, Ta3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 76967
Homologene: 8839
Usp8
Name: ubiquitin specific peptidase 8
Synonyms: Ubpy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 84092
Homologene: 3782
Vps13a
Name: vacuolar protein sorting 13A
Synonyms: 4930543C13Rik, 4930516E05Rik, D330038K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 271564
VEGA: 19
HGNC: HGNC:1908
Homologene: 22068
Slc11a2
Name: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
Synonyms: van, microcytic anemia, viable anaemia, DCT1, DMT1, Nramp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 18174
Homologene: 55471
Capn11
Name: calpain 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268958
HGNC: HGNC:1478
Homologene: 21392
Lama2
Name: laminin, alpha 2
Synonyms: mer, merosin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Muc4
Name: mucin 4
Synonyms: 4933405I11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 140474
HGNC: HGNC:7514
Homologene: 124469
Nalcn
Name: sodium leak channel, non-selective
Synonyms: A530023G15Rik, Vgcnl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 338370
VEGA: 14
Homologene: 21832
Tpo
Name: thyroid peroxidase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 22018
Homologene: 461
Ly75
Name: lymphocyte antigen 75
Synonyms: CD205, DEC-205
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17076
HGNC: HGNC:6729
Homologene: 31085
Olfr1285
Name: olfactory receptor 1285
Synonyms: MOR248-17P, GA_x6K02T2Q125-72459956-72460837, MOR248-25_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 545447
Rbbp8
Name: retinoblastoma binding protein 8, endonuclease
Synonyms: 9930104E21Rik, CtIP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225182
VEGA: 18
HGNC: HGNC:9891
Homologene: 28546
Ivns1abp
Name: influenza virus NS1A binding protein
Synonyms: NS1-BP, HSPC068, Nd1-L, Nd1-S, NS-1, 1700126I16Rik, ND1, 1190004M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 117198
Homologene: 31384
Tectb
Name: tectorin beta
Synonyms: [b]-tectorin, Tctnb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 21684
Homologene: 7568
Rhoj
Name: ras homolog family member J
Synonyms: Arhj, TC10L, TCL, 1110005O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 80837
HGNC: HGNC:688
Homologene: 56894
Tmc6
Name: transmembrane channel-like gene family 6
Synonyms: EVER1, D11Ertd204e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217353
Homologene: 5258
Vmn2r11
Name: vomeronasal 2, receptor 11
Synonyms: EG384219
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 384219
Homologene: 129606
Ptpru
Name: protein tyrosine phosphatase, receptor type, U
Synonyms: Ptprl, RPTPlambda
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Gad1-ps
Name: glutamate decarboxylase 1, pseudogene
Synonyms: Gad-1ps
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 382407
VEGA: 10
Olfr1444
Name: olfactory receptor 1444
Synonyms: MOR202-4, GA_x6K02T2RE5P-3191201-3192160
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258697
Homologene: 64906
Antxr1
Name: anthrax toxin receptor 1
Synonyms: Tem8, 2810405N18Rik, 2310008J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 69538
Homologene: 12976
Ifna6
Name: interferon alpha 6
Synonyms: Ifna8, Ifa6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 15969
HGNC: HGNC:5425
Homologene: 68536
Gpr45
Name: G protein-coupled receptor 45
Synonyms: 9230112G11Rik, PSP24alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 93690
HGNC: HGNC:4503
Homologene: 5228
Gpr141b
Name: G protein-coupled receptor 141B
Synonyms: A530099J19Rik, Karma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 319293
Homologene: 105930
Exoc3l4
Name: exocyst complex component 3-like 4
Synonyms: 1600013K19Rik, 1200009I06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 74190
VEGA: 12
Homologene: 41760
Synpo
Name: synaptopodin
Synonyms: 9030217H17Rik, 9330140I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 104027
Homologene: 5274
Clip4
Name: CAP-GLY domain containing linker protein family, member 4
Synonyms: Rsnl2, 1700024K14Rik, 1700074B05Rik, 5830409B12Rik, 4833417L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78785
VEGA: 17
Homologene: 11662
Arhgap45
Name: Rho GTPase activating protein 45
Synonyms: Hmha1, 6330406L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70719
Homologene: 69120
4930444G20Rik
Name: RIKEN cDNA 4930444G20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 114671
Homologene: 130042
H2-Eb1
Name: histocompatibility 2, class II antigen E beta
Synonyms: H-2Eb, Ia-4, Ia4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14969
HGNC: HGNC:4953
Homologene: 101524
Slc22a28
Name: solute carrier family 22, member 28
Synonyms: Gm5631
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 434674
VEGA: 19
Homologene: 77136
Pcsk1
Name: proprotein convertase subtilisin/kexin type 1
Synonyms: Phpp-1, PC3, prohormone convertase 1/3, SPC3, PC1, Nec1, Nec-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18548
HGNC: HGNC:8743
Homologene: 379
Ska1
Name: spindle and kinetochore associated complex subunit 1
Synonyms: 2810433K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 66468
VEGA: 18
Homologene: 11975
Ttyh3
Name: tweety family member 3
Synonyms: 2900029G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 78339
Homologene: 18431
H2-Ke6
Name: H2-K region expressed gene 6
Synonyms: Ring2, H-2Ke6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 14979
HGNC: HGNC:3554
Homologene: 56588
Olfr1388
Name: olfactory receptor 1388
Synonyms: MOR256-28, GA_x6K02T2QP88-5991012-5990077
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258459
Homologene: 74258
Nhlrc1
Name: NHL repeat containing 1
Synonyms: B230309E09Rik, Malin, EPM2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 105193
VEGA: 13
Homologene: 18439
Igkv9-120
Name: immunoglobulin kappa chain variable 9-120
Synonyms: Gm5571
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 434025
Golga7
Name: golgi autoantigen, golgin subfamily a, 7
Synonyms: GOLGA3AP1, HSPC041, C130038N16Rik, GCP16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 57437
Homologene: 9385
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 43,033,058 bp
  • G to T, chromosome 1 at 151,354,009 bp
  • A to G, chromosome 1 at 166,146,791 bp
  • T to C, chromosome 2 at 60,308,311 bp
  • C to T, chromosome 2 at 111,408,473 bp
  • A to G, chromosome 2 at 126,742,425 bp
  • G to A, chromosome 3 at 144,921,863 bp
  • A to T, chromosome 4 at 88,827,669 bp
  • A to G, chromosome 4 at 98,765,461 bp
  • T to A, chromosome 4 at 129,008,247 bp
  • T to A, chromosome 4 at 131,820,190 bp
  • A to G, chromosome 5 at 109,054,906 bp
  • T to A, chromosome 5 at 140,631,552 bp
  • G to A, chromosome 6 at 68,050,273 bp
  • T to A, chromosome 6 at 85,629,208 bp
  • C to T, chromosome 6 at 87,217,273 bp
  • C to T, chromosome 8 at 23,250,344 bp
  • T to C, chromosome 8 at 87,782,327 bp
  • T to A, chromosome 10 at 22,066,843 bp
  • A to T, chromosome 10 at 27,190,544 bp
  • A to G, chromosome 10 at 80,025,476 bp
  • T to C, chromosome 10 at 83,570,028 bp
  • A to T, chromosome 10 at 99,444,533 bp
  • T to C, chromosome 11 at 49,444,313 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • A to G, chromosome 11 at 117,775,615 bp
  • A to G, chromosome 12 at 30,119,491 bp
  • T to C, chromosome 12 at 58,267,826 bp
  • G to T, chromosome 12 at 71,164,546 bp
  • A to T, chromosome 12 at 71,164,547 bp
  • A to T, chromosome 12 at 75,393,969 bp
  • T to C, chromosome 12 at 111,423,417 bp
  • A to G, chromosome 13 at 19,729,295 bp
  • A to G, chromosome 13 at 47,013,717 bp
  • A to G, chromosome 13 at 75,097,907 bp
  • A to T, chromosome 13 at 94,528,257 bp
  • T to A, chromosome 14 at 7,890,843 bp
  • A to G, chromosome 14 at 123,295,406 bp
  • A to C, chromosome 15 at 98,907,608 bp
  • A to G, chromosome 15 at 100,403,288 bp
  • A to G, chromosome 16 at 32,753,720 bp
  • T to C, chromosome 17 at 32,338,292 bp
  • T to C, chromosome 17 at 34,026,461 bp
  • C to A, chromosome 17 at 34,314,255 bp
  • C to T, chromosome 17 at 45,639,674 bp
  • A to C, chromosome 17 at 71,789,883 bp
  • A to G, chromosome 18 at 11,742,642 bp
  • T to C, chromosome 18 at 60,595,950 bp
  • C to T, chromosome 18 at 61,019,899 bp
  • G to T, chromosome 18 at 74,196,996 bp
  • A to G, chromosome 19 at 6,068,194 bp
  • A to T, chromosome 19 at 8,131,431 bp
  • A to T, chromosome 19 at 12,861,807 bp
  • G to A, chromosome 19 at 16,715,100 bp
  • T to C, chromosome 19 at 55,192,627 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5671 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043314-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.