Strain Name:
C57BL/6J-MtgxR5678Btlr
Stock Number:
043317-MU
Citation ID:
RRID:MMRRC_043317-MU
Other Names:
R5678 (G1)
Major Collection:

Gene Information

Utrn
Name: utrophin
Synonyms: G-utrophin, Dmdl, DRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22288
VEGA: 10
Homologene: 21398
Atrn
Name: attractin
Synonyms: Mgca
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11990
HGNC: HGNC:885
Homologene: 22542
Npy1r
Name: neuropeptide Y receptor Y1
Synonyms: Y1-R, Npyr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 18166
HGNC: HGNC:7956
Homologene: 700
Utp20
Name: UTP20 small subunit processome component
Synonyms: DRIM, mDRIM, 3830408P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70683
VEGA: 10
Homologene: 38373
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77595
Homologene: 28122
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: G1-419-52, 4930523M17Rik, 1500002J22Rik, eIF4GII, repro8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Setd2
Name: SET domain containing 2
Synonyms: 4921524K10Rik, KMT3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235626
Homologene: 56493
Ints3
Name: integrator complex subunit 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229543
Homologene: 11309
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
Tasor
Name: transcription activation suppressor
Synonyms: D14Abb1e, Fam208a, 4933409E02Rik, MommeD6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218850
VEGA: 14
Homologene: 9062
Rps6ka5
Name: ribosomal protein S6 kinase, polypeptide 5
Synonyms: 6330404E13Rik, MSK1, 3110005L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 73086
VEGA: 12
Homologene: 48302
Gm14124
Name: predicted gene 14124
Synonyms: Gm10749, EG640962
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 100216455
Homologene: 134546
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Fndc3b
Name: fibronectin type III domain containing 3B
Synonyms: 1600019O04Rik, fad104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72007
Homologene: 11244
Prune2
Name: prune homolog 2
Synonyms: A230083H22Rik, A330102H22Rik, 6330414G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 353211
VEGA: 19
Homologene: 18939
Epha6
Name: Eph receptor A6
Synonyms: m-ehk2, Ehk2, Hek12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13840
Homologene: 56396
Srpk2
Name: serine/arginine-rich protein specific kinase 2
Synonyms: WBP6, mSRPK2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20817
Homologene: 101663
Baz1a
Name: bromodomain adjacent to zinc finger domain 1A
Synonyms: Wcrf180, Acf1, Gtl5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217578
HGNC: HGNC:960
Homologene: 45654
Sympk
Name: symplekin
Synonyms: 1500016F02Rik, 4632415H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 68188
Homologene: 37969
Cep295
Name: centrosomal protein 295
Synonyms: LOC382128, 5830418K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319675
Homologene: 27936
Col1a2
Name: collagen, type I, alpha 2
Synonyms: Cola2, Cola-2, Col1a-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12843
HGNC: HGNC:2198
Homologene: 69
Clcn1
Name: chloride channel, voltage-sensitive 1
Synonyms: Clc-1, NMF355, SMCC1, nmf355, Clc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12723
HGNC: HGNC:2019
Homologene: 63
Art3
Name: ADP-ribosyltransferase 3
Synonyms: 4930569O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 109979
HGNC: HGNC:725
Homologene: 911
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Acsl1
Name: acyl-CoA synthetase long-chain family member 1
Synonyms: Facl2, Acas1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 14081
HGNC: HGNC:3569
Homologene: 37561
Dscam
Name: DS cell adhesion molecule
Synonyms: Down syndrome cell adhesion molecule, 4932410A21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 13508
HGNC: HGNC:3039
Homologene: 74393
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215772
Homologene: 100289
Aatk
Name: apoptosis-associated tyrosine kinase
Synonyms: AATYK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11302
HGNC: HGNC:21
Homologene: 74861
Tmed11
Name: transmembrane p24 trafficking protein 11
Synonyms: 1810008K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 67366
Homologene: 48721
Tnrc18
Name: trinucleotide repeat containing 18
Synonyms: Zfp469, EG381742
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231861
Homologene: 45603
Dstyk
Name: dual serine/threonine and tyrosine protein kinase
Synonyms: C430014H23Rik, A930019K20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 213452
Homologene: 19711
Ccdc40
Name: coiled-coil domain containing 40
Synonyms: B930008I02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 207607
Homologene: 27890
Olfr978
Name: olfactory receptor 978
Synonyms: GA_x6K02T2PVTD-33692287-33693222, MOR223-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 259109
VEGA: 9
Homologene: 88420
3425401B19Rik
Name: RIKEN cDNA 3425401B19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100504518
VEGA: 14
Homologene: 54908
Slc66a2
Name: solute carrier family 66 member 2
Synonyms: C78974, 4933425L21Rik, Pqlc1, 5730564E11Rik, 2310009N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 66943
Homologene: 32623
Tchh
Name: trichohyalin
Synonyms: Thh, AHF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99681
Homologene: 136273
Esrp2
Name: epithelial splicing regulatory protein 2
Synonyms: Rbm35b, 9530027K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 77411
Homologene: 32617
Dhrs7
Name: dehydrogenase/reductase (SDR family) member 7
Synonyms: retDSR4, retSDR4, 5730564L20Rik, 2310016E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66375
VEGA: 12
Homologene: 9350
Zfp119a
Name: zinc finger protein 119a
Synonyms: Zfp119, Mzf13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 104349
Olfr1248
Name: olfactory receptor 1248
Synonyms: GA_x6K02T2Q125-51059648-51058725, MOR231-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258787
Homologene: 133613
Csrnp2
Name: cysteine-serine-rich nuclear protein 2
Synonyms: CSRNP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 207785
VEGA: 15
Homologene: 32743
Qdpr
Name: quinoid dihydropteridine reductase
Synonyms: 2610008L04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 110391
HGNC: HGNC:9752
Homologene: 271
1700093K21Rik
Name: RIKEN cDNA 1700093K21 gene
Synonyms: b2b3025Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67358
Homologene: 49849
Cd164
Name: CD164 antigen
Synonyms: A24, MGC-24, A115
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 53599
HGNC: HGNC:1632
Homologene: 38129
Gm13762
Name: predicted gene 13762
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Ighv5-9-1
Name: immunoglobulin heavy variable 5-9-1
Synonyms: Gm16886
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 641178
Lamtor2
Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Synonyms: Mapbpip, 2010111E04Rik, Rab25, Robld3, P14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 83409
Homologene: 8518
A530016L24Rik
Name: RIKEN cDNA A530016L24 gene
Synonyms: Nrac
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319942
VEGA: 12
Homologene: 52221
Gm8257
Name: predicted pseudogene 8257
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 666725
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 132,453,291 bp
  • A to T, chromosome 2 at 88,972,973 bp
  • A to G, chromosome 2 at 89,617,281 bp
  • T to C, chromosome 2 at 130,970,016 bp
  • A to T, chromosome 2 at 150,268,505 bp
  • A to G, chromosome 3 at 27,429,023 bp
  • A to G, chromosome 3 at 88,550,794 bp
  • T to C, chromosome 3 at 90,190,959 bp
  • A to G, chromosome 3 at 90,403,548 bp
  • A to T, chromosome 3 at 93,445,626 bp
  • A to G, chromosome 4 at 138,151,742 bp
  • TCA to T, chromosome 5 at 23,524,606 bp
  • T to C, chromosome 5 at 45,447,637 bp
  • T to C, chromosome 5 at 92,392,550 bp
  • T to C, chromosome 5 at 108,786,165 bp
  • T to C, chromosome 5 at 142,733,564 bp
  • C to T, chromosome 6 at 4,536,239 bp
  • A to G, chromosome 6 at 42,307,265 bp
  • T to C, chromosome 7 at 19,049,472 bp
  • T to C, chromosome 7 at 120,077,851 bp
  • T to A, chromosome 8 at 46,492,850 bp
  • T to C, chromosome 8 at 66,704,203 bp
  • G to A, chromosome 8 at 106,132,118 bp
  • T to C, chromosome 9 at 15,322,858 bp
  • T to C, chromosome 9 at 39,993,903 bp
  • C to T, chromosome 9 at 95,951,487 bp
  • A to G, chromosome 9 at 110,602,186 bp
  • T to G, chromosome 10 at 10,431,326 bp
  • A to G, chromosome 10 at 12,442,018 bp
  • T to C, chromosome 10 at 41,519,952 bp
  • A to T, chromosome 10 at 88,809,117 bp
  • T to C, chromosome 11 at 23,516,529 bp
  • T to C, chromosome 11 at 119,231,572 bp
  • T to C, chromosome 11 at 120,010,154 bp
  • T to C, chromosome 12 at 7,991,494 bp
  • T to C, chromosome 12 at 54,900,532 bp
  • C to T, chromosome 12 at 72,657,332 bp
  • T to C, chromosome 12 at 100,724,876 bp
  • T to G, chromosome 12 at 112,496,872 bp
  • T to C, chromosome 12 at 113,736,587 bp
  • CGCGGCGGCGGCGGCGG to CGCGGCGGCGGCGGCGGCGGCGG, chromosome 14 at 27,429,123 bp
  • T to A, chromosome 14 at 32,662,053 bp
  • A to T, chromosome 14 at 44,657,249 bp
  • T to C, chromosome 15 at 100,481,804 bp
  • A to T, chromosome 16 at 59,818,979 bp
  • A to G, chromosome 16 at 96,790,900 bp
  • T to C, chromosome 17 at 55,868,336 bp
  • T to C, chromosome 18 at 80,257,034 bp
  • A to G, chromosome 19 at 17,118,668 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5678 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043317-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.