Strain Name:
C57BL/6J-MtgxR5691Btlr
Stock Number:
043324-MU
Citation ID:
RRID:MMRRC_043324-MU
Other Names:
R5691 (G1)
Major Collection:

Gene Information

Nrcam
Name: neuronal cell adhesion molecule
Synonyms: C030017F07Rik, Bravo, C130076O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319504
VEGA: 12
HGNC: HGNC:7994
Homologene: 21041
Kdm4c
Name: lysine (K)-specific demethylase 4C
Synonyms: 2410141F18Rik, Jmjd2c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 76804
Homologene: 41004
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: D230004K18Rik, b2b1625.2Clo, Gp330, Megalin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Setd3
Name: SET domain containing 3
Synonyms: D12Ertd771e, 2610305M23Rik, 2610102I01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 52690
Homologene: 41748
Dlgap4
Name: DLG associated protein 4
Synonyms: SAP90/PSD-95-associated protein 4, DAP4, PSD-95/SAP90 binding protein 4, Sapap4, WBP16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228836
Homologene: 8935
Zfp106
Name: zinc finger protein 106
Synonyms: Cd-1, sirm, Sh3bp3, H3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20402
Homologene: 40787
Trps1
Name: transcriptional repressor GATA binding 1
Synonyms: D15Ertd586e, trichorhinophalangeal syndrome I (human)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 83925
Homologene: 8556
Zfp90
Name: zinc finger protein 90
Synonyms: Nk10 expressed protein, NK10, Zfp83, KRAB17, 6430515L01Rik, Zfp64
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 22751
Homologene: 86800
Nova1
Name: neuro-oncological ventral antigen 1
Synonyms: Nova-1, 9430099M15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 664883
VEGA: 12
HGNC: HGNC:7886
Homologene: 21296
Ap4m1
Name: adaptor-related protein complex AP-4, mu 1
Synonyms: 4930443L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 11781
HGNC: HGNC:574
Homologene: 3467
Dcc
Name: deleted in colorectal carcinoma
Synonyms: Igdcc1, C030036D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13176
HGNC: HGNC:2701
Homologene: 21081
Sp3
Name: trans-acting transcription factor 3
Synonyms: D130027J01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20687
Homologene: 7952
Iqcd
Name: IQ motif containing D
Synonyms: 4933433C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 75732
Homologene: 49921
Fan1
Name: FANCD2/FANCI-associated nuclease 1
Synonyms: 6030441H18Rik, Mtmr15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 330554
Homologene: 45598
Ncoa2
Name: nuclear receptor coactivator 2
Synonyms: SRC-2, TIF-2, D1Ertd433e, TIF2, Grip1, bHLHe75, glucocorticoid receptor-interacting protein 1, KAT13C, TIF2/GRIP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17978
HGNC: HGNC:7669
Homologene: 4768
Bcl10
Name: B cell leukemia/lymphoma 10
Synonyms: mE10, BCL-10, cE10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12042
HGNC: HGNC:989
Homologene: 2912
Selenot
Name: selenoprotein T
Synonyms: Selt, 5730408P04Rik, SelT, 2810407C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 69227
Homologene: 32304
Plekhm2
Name: pleckstrin homology domain containing, family M (with RUN domain) member 2
Synonyms: 2310034J19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 69582
Homologene: 19575
Pgam5
Name: phosphoglycerate mutase family member 5
Synonyms: 2610528A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 72542
Homologene: 14597
Cdc123
Name: cell division cycle 123
Synonyms: G431001I09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 98828
Homologene: 4394
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 269700
Homologene: 28297
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: 9330101J02Rik, Ttc40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 212124
Tespa1
Name: thymocyte expressed, positive selection associated 1
Synonyms: Itprid3, 5830405N20Rik, A430001F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67596
VEGA: 10
Homologene: 106645
Mroh7
Name: maestro heat-like repeat family member 7
Synonyms: Gm1027, LOC381538, Heatr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381538
Homologene: 19633
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: D12Ertd777e, Nesp2g, nesprin-2, syne-2, dice, Cpfl8, 6820443O06Rik, diminished cone electroretinogram
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 319565
Homologene: 56700
P3h3
Name: prolyl 3-hydroxylase 3
Synonyms: Grcb, Leprel2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 14789
Homologene: 8401
Gm6614
Name: predicted gene 6614
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 625716
Homologene: 87075
Nadsyn1
Name: NAD synthetase 1
Synonyms: 9130012B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 78914
Homologene: 6098
Ifi207
Name: interferon activated gene 207
Synonyms: Pyhin-A, AI607873
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226691
HGNC: HGNC:5395
Homologene: 115929
Rabgap1l
Name: RAB GTPase activating protein 1-like
Synonyms: 5830411O09Rik, 8430421H08Rik, Hh1, 9630005B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 29809
Homologene: 8143
Nubpl
Name: nucleotide binding protein-like
Synonyms: 2410170E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 76826
Homologene: 11854
Vmn2r73
Name: vomeronasal 2, receptor 73
Synonyms: EG620928
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 620928
Homologene: 115466
Abcb5
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 5
Synonyms: 9230106F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 77706
HGNC: HGNC:46
Homologene: 83488
Inpp4b
Name: inositol polyphosphate-4-phosphatase, type II
Synonyms: E130107I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234515
HGNC: HGNC:6075
Homologene: 20832
Eqtn
Name: equatorin, sperm acrosome associated
Synonyms: equatorin, 1700028B15Rik, Afaf, 4930579C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 67753
HGNC: HGNC:1359
Homologene: 75250
Hid1
Name: HID1 domain containing
Synonyms: C630004H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217310
Homologene: 12737
Fbxo17
Name: F-box protein 17
Synonyms: FBXO26, Fbx17, Fbg4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 50760
Homologene: 17523
Slc22a27
Name: solute carrier family 22, member 27
Synonyms: mOAT6 related protein, AB056442
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 171405
Homologene: 77136
Oasl2
Name: 2'-5' oligoadenylate synthetase-like 2
Synonyms: Mmu-OASL, M1204
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 23962
Homologene: 128369
Olfr1099
Name: olfactory receptor 1099
Synonyms: MOR206-3, GA_x6K02T2Q125-48446067-48445129
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258764
Homologene: 107003
Mgat4e
Name: MGAT4 family, member E
Synonyms: 4931440L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 71001
Homologene: 129994
Gm13084
Name: predicted gene 13084
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381569
Homologene: 77858
Parp14
Name: poly (ADP-ribose) polymerase family, member 14
Synonyms: CoaSt6, collaborator of Stat6, 1600029O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 547253
Homologene: 19697
Lrrc69
Name: leucine rich repeat containing 69
Synonyms: 1700034K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 73314
Homologene: 78018
Jph1
Name: junctophilin 1
Synonyms: JP-1, mitsugumin72, ENSMUSG00000054314
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 57339
Homologene: 10761
Rps3a2
Name: ribosomal protein S3A2
Synonyms: Gm10119
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 100043780
Ermn
Name: ermin, ERM-like protein
Synonyms: A330104H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 77767
Homologene: 12683
Aqp7
Name: aquaporin 7
Synonyms: AQP7L, AQPap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11832
HGNC: HGNC:640
Homologene: 48000
Prss21
Name: protease, serine 21
Synonyms: testisin, mT4, 1700023E12Rik, TESP5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 57256
HGNC: HGNC:9485
Homologene: 137342
Phpt1
Name: phosphohistidine phosphatase 1
Synonyms: 1700008C22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75454
Homologene: 8573
Tmc7
Name: transmembrane channel-like gene family 7
Synonyms: C630024K23Rik, 1700030H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 209760
Homologene: 36424
Defb46
Name: defensin beta 46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 574081
Riox1
Name: ribosomal oxygenase 1
Synonyms: NO66, 2410016O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 71952
VEGA: 12
Homologene: 11366
Gm9745
Name: predicted gene 9745
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 100039655
2410022M11Rik
Name: RIKEN cDNA 2410022M11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 100503842
Tcl1b4
Name: T cell leukemia/lymphoma 1B, 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 27380
VEGA: 12
Homologene: 83274
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 13,180,550 bp
  • T to G, chromosome 1 at 17,004,363 bp
  • A to T, chromosome 1 at 134,540,991 bp
  • A to T, chromosome 1 at 160,735,684 bp
  • A to G, chromosome 1 at 173,732,426 bp
  • T to A, chromosome 2 at 5,823,175 bp
  • T to C, chromosome 2 at 25,573,695 bp
  • A to T, chromosome 2 at 58,047,764 bp
  • T to C, chromosome 2 at 69,502,553 bp
  • A to G, chromosome 2 at 72,971,459 bp
  • A to T, chromosome 2 at 86,959,272 bp
  • G to A, chromosome 2 at 120,524,471 bp
  • A to G, chromosome 2 at 156,704,470 bp
  • C to T, chromosome 3 at 58,586,026 bp
  • C to T, chromosome 3 at 145,933,149 bp
  • T to A, chromosome 4 at 14,769,648 bp
  • G to A, chromosome 4 at 41,035,510 bp
  • A to T, chromosome 4 at 74,334,728 bp
  • C to A, chromosome 4 at 94,923,728 bp
  • C to A, chromosome 4 at 106,702,618 bp
  • A to C, chromosome 4 at 141,628,289 bp
  • A to T, chromosome 4 at 143,812,009 bp
  • G to A, chromosome 5 at 110,267,093 bp
  • C to A, chromosome 5 at 114,899,767 bp
  • C to T, chromosome 5 at 120,602,506 bp
  • A to G, chromosome 5 at 121,348,815 bp
  • A to G, chromosome 5 at 138,172,391 bp
  • C to T, chromosome 6 at 124,855,153 bp
  • A to T, chromosome 6 at 141,994,855 bp
  • G to A, chromosome 7 at 28,737,472 bp
  • C to A, chromosome 7 at 64,354,370 bp
  • A to G, chromosome 7 at 85,858,091 bp
  • T to C, chromosome 7 at 118,541,893 bp
  • T to C, chromosome 7 at 139,606,700 bp
  • C to T, chromosome 7 at 143,812,579 bp
  • T to A, chromosome 8 at 19,242,133 bp
  • T to A, chromosome 8 at 81,890,694 bp
  • C to A, chromosome 8 at 106,425,078 bp
  • T to A, chromosome 10 at 130,354,769 bp
  • A to G, chromosome 11 at 115,348,819 bp
  • T to C, chromosome 12 at 44,564,256 bp
  • T to C, chromosome 12 at 46,816,955 bp
  • G to A, chromosome 12 at 52,105,276 bp
  • TCCAGGTAGGGCACACC to TCC, chromosome 12 at 76,027,856 bp
  • C to T, chromosome 12 at 83,951,692 bp
  • C to A, chromosome 12 at 105,202,547 bp
  • A to T, chromosome 12 at 108,160,285 bp
  • A to T, chromosome 12 at 118,927,235 bp
  • A to T, chromosome 13 at 8,942,657 bp
  • A to G, chromosome 14 at 56,812,373 bp
  • G to T, chromosome 14 at 88,123,047 bp
  • T to A, chromosome 15 at 50,827,304 bp
  • A to G, chromosome 16 at 35,863,539 bp
  • A to G, chromosome 17 at 23,868,785 bp
  • T to C, chromosome 18 at 71,575,083 bp
  • T to C, chromosome 19 at 7,926,670 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5691 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043324-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.