Strain Name:
C57BL/6J-MtgxR5695Btlr
Stock Number:
043326-MU
Citation ID:
RRID:MMRRC_043326-MU
Other Names:
R5695 (G1)
Major Collection:

Gene Information

Sulf2
Name: sulfatase 2
Synonyms: 2010004N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 72043
Homologene: 10313
Wrn
Name: Werner syndrome RecQ like helicase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 22427
Homologene: 6659
Gon4l
Name: gon-4-like (C.elegans)
Synonyms: 2610100B20Rik, 1500041I23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 76022
Homologene: 13002
Eif4g3
Name: eukaryotic translation initiation factor 4 gamma, 3
Synonyms: eIF4GII, G1-419-52, repro8, 4930523M17Rik, 1500002J22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230861
HGNC: HGNC:3298
Homologene: 2789
Cdca2
Name: cell division cycle associated 2
Synonyms: 2610311M19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 108912
Homologene: 18444
Aspm
Name: abnormal spindle microtubule assembly
Synonyms: Sha1, D330028K02Rik, Calmbp1, Aspm, MCPH5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12316
Homologene: 7650
Epc2
Name: enhancer of polycomb homolog 2
Synonyms: D2Ertd694e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227867
Homologene: 32274
Nup214
Name: nucleoporin 214
Synonyms: D2H9S46E, CAN
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227720
HGNC: HGNC:8064
Homologene: 38008
Lpin2
Name: lipin 2
Synonyms: 2610511G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 64898
Homologene: 8769
Supt16
Name: SPT16, facilitates chromatin remodeling subunit
Synonyms: Fact140, Supt16h, Spt16, Cdc68
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 114741
VEGA: 14
Homologene: 5207
Hipk2
Name: homeodomain interacting protein kinase 2
Synonyms: Stank, B230339E18Rik, 1110014O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 15258
Homologene: 68766
Pacs1
Name: phosphofurin acidic cluster sorting protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107975
VEGA: 19
Homologene: 9970
Phrf1
Name: PHD and ring finger domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 101471
Homologene: 16377
Oas1d
Name: 2'-5' oligoadenylate synthetase 1D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100535
HGNC: HGNC:8086
Homologene: 110815
Rbm33
Name: RNA binding motif protein 33
Synonyms: 3200001K10Rik, 6430512A10Rik, Prr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 381626
Homologene: 137386
Gtpbp1
Name: GTP binding protein 1
Synonyms: GTPBP1, GP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 14904
VEGA: 15
HGNC: HGNC:4669
Homologene: 3165
Gcnt2
Name: glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
Synonyms: IGnTC, IGnTB, IGnTA, 5330430K10Rik, IGnT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 14538
VEGA: 13
HGNC: HGNC:4204
Homologene: 41535
Enpp1
Name: ectonucleotide pyrophosphatase/phosphodiesterase 1
Synonyms: Ly-41, CD203c, PC-1, NPP1, E-NPP1, 4833416E15Rik, twy, Npps, Pca, Pdnp1, Pca-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 18605
HGNC: HGNC:3356
Homologene: 38151
Pcdh17
Name: protocadherin 17
Synonyms: LOC219228, C030033F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219228
VEGA: 14
Homologene: 8700
Anapc4
Name: anaphase promoting complex subunit 4
Synonyms: D5Ertd249e, APC4, 2610306D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 52206
Homologene: 40873
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hy-3, hy3, 1700034M11Rik, hyrh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244653
Homologene: 52118
Cmya5
Name: cardiomyopathy associated 5
Synonyms: 2310076E16Rik, Myospryn, 2310076E21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 76469
VEGA: 13
Homologene: 137367
Enpep
Name: glutamyl aminopeptidase
Synonyms: Ly51, APA, Bp-1/6C3, 6030431M22Rik, aminopeptidase-A, Ly-51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 13809
HGNC: HGNC:3355
Homologene: 68216
Olfr901
Name: olfactory receptor 901
Synonyms: MOR162-8, GA_x6K02T2PVTD-32123032-32123967
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258028
VEGA: 9
HGNC: null
Homologene: 79399
Ralgapa2
Name: Ral GTPase activating protein, alpha subunit 2 (catalytic)
Synonyms: AS250, RGC2, A230067G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241694
Homologene: 28131
Fras1
Name: Fraser extracellular matrix complex subunit 1
Synonyms: E130113P14Rik, bl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231470
Homologene: 23516
Cgn
Name: cingulin
Synonyms: 6330408J11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 70737
Homologene: 41394
Sorbs2
Name: sorbin and SH3 domain containing 2
Synonyms: 2010203O03Rik, 9430041O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234214
Homologene: 83295
Vmn2r84
Name: vomeronasal 2, receptor 84
Synonyms: EG625068
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 625068
HGNC: null
Homologene: 129606
Gmpr2
Name: guanosine monophosphate reductase 2
Synonyms: 1810008P16Rik, 5730544D12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105446
VEGA: 14
HGNC: HGNC:4377
Homologene: 22983
Bpifb4
Name: BPI fold containing family B, member 4
Synonyms: LOC381399, Gm1006
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 381399
Homologene: 66971
Rtl1
Name: retrotransposon Gaglike 1
Synonyms: Mart1, Mor1, Mar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 353326
VEGA: 12
Homologene: 120261
Abcd4
Name: ATP-binding cassette, sub-family D (ALD), member 4
Synonyms: Pxmp1l, P69r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 19300
VEGA: 12
HGNC: HGNC:68
Homologene: 3703
Kctd1
Name: potassium channel tetramerisation domain containing 1
Synonyms: 4933402K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 106931
VEGA: 18
Homologene: 65999
Ano8
Name: anoctamin 8
Synonyms: Tmem16h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 382014
Homologene: 124473
Slc2a4
Name: solute carrier family 2 (facilitated glucose transporter), member 4
Synonyms: Glut4, twgy, Glut-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20528
Homologene: 74381
Cntnap3
Name: contactin associated protein-like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 238680
VEGA: 13
Homologene: 129602
Olfr986
Name: olfactory receptor 986
Synonyms: MOR104-3, GA_x6K02T2PVTD-33886895-33887833
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258608
VEGA: 9
Homologene: 105185
Lax1
Name: lymphocyte transmembrane adaptor 1
Synonyms: E430019B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240754
Homologene: 49504
Ehf
Name: ets homologous factor
Synonyms: 9030625L19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 13661
HGNC: HGNC:3246
Homologene: 7301
Hhat
Name: hedgehog acyltransferase
Synonyms: Skn, 2810432O22Rik, AP-2CRE, Tg(TFAP2A-cre)1Will
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226861
Homologene: 41232
Entpd8
Name: ectonucleoside triphosphate diphosphohydrolase 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 72090
Homologene: 77857
Vps9d1
Name: VPS9 domain containing 1
Synonyms: 1300018I17Rik, 2410004N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 72325
Homologene: 21021
Fank1
Name: fibronectin type 3 and ankyrin repeat domains 1
Synonyms: 1700007B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 66930
Homologene: 12055
Plekhb1
Name: pleckstrin homology domain containing, family B (evectins) member 1
Synonyms: PHR1, evt-1, Phret1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 27276
Homologene: 8449
Nyap1
Name: neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
Synonyms: Nyap1, 6430598A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 243300
Homologene: 18320
Bend7
Name: BEN domain containing 7
Synonyms: 1110017O21Rik, E130319B15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 209645
Homologene: 17660
Olfr724
Name: olfactory receptor 724
Synonyms: GA_x6K02T2PMLR-5645801-5644872, MOR247-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258485
Homologene: 71986
Erich3
Name: glutamate rich 3
Synonyms: 5031409G23Rik, 4922501L14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 209601
Homologene: 27877
Vmn1r26
Name: vomeronasal 1 receptor 26
Synonyms: V1rc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 171190
HGNC: null
Homologene: null
Crnn
Name: cornulin
Synonyms: LOC381457
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 381457
HGNC: HGNC:1230
Homologene: 9416
Cbx8
Name: chromobox 8
Synonyms: Pc3, polycomb 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 30951
Homologene: 32199
Vmn2r39
Name: vomeronasal 2, receptor 39
Synonyms: EG545909
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 545909
HGNC: null
Homologene: 113703
Igfbpl1
Name: insulin-like growth factor binding protein-like 1
Synonyms: 2810453O06Rik, 2810011G06Rik, IGFBP-like protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 75426
Homologene: 10292
Morn4
Name: MORN repeat containing 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 226123
VEGA: 19
Homologene: 16635
Gm20830
Name: predicted gene, 20830
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
Alteration at locus: Chemically Induced
NCBI: 108168638
HGNC: null
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 133,680,578 bp
  • G to A, chromosome 1 at 139,479,669 bp
  • A to T, chromosome 1 at 192,717,019 bp
  • G to A, chromosome 2 at 4,763,241 bp
  • A to G, chromosome 2 at 25,084,334 bp
  • C to A, chromosome 2 at 32,034,373 bp
  • T to A, chromosome 2 at 49,547,607 bp
  • T to A, chromosome 2 at 103,266,779 bp
  • T to C, chromosome 2 at 146,333,477 bp
  • G to A, chromosome 2 at 153,942,923 bp
  • G to A, chromosome 2 at 166,132,758 bp
  • TGAGCA to TGAGCAGAGCA, chromosome 3 at 88,896,216 bp
  • A to G, chromosome 3 at 93,149,023 bp
  • G to A, chromosome 3 at 94,773,635 bp
  • C to T, chromosome 3 at 129,309,099 bp
  • G to T, chromosome 3 at 154,733,573 bp
  • A to T, chromosome 4 at 45,826,374 bp
  • T to A, chromosome 4 at 138,163,433 bp
  • A to T, chromosome 5 at 28,339,012 bp
  • C to T, chromosome 5 at 52,862,239 bp
  • A to G, chromosome 5 at 96,781,344 bp
  • T to C, chromosome 5 at 120,915,011 bp
  • C to T, chromosome 5 at 137,734,984 bp
  • A to T, chromosome 6 at 38,818,875 bp
  • A to T, chromosome 6 at 58,008,753 bp
  • T to A, chromosome 7 at 9,025,151 bp
  • A to T, chromosome 7 at 100,655,395 bp
  • A to G, chromosome 7 at 133,869,346 bp
  • A to G, chromosome 7 at 141,258,465 bp
  • C to A, chromosome 8 at 33,324,318 bp
  • A to T, chromosome 8 at 45,792,875 bp
  • A to C, chromosome 8 at 71,483,243 bp
  • A to T, chromosome 8 at 110,535,283 bp
  • T to C, chromosome 8 at 123,246,916 bp
  • A to G, chromosome 9 at 38,431,176 bp
  • T to C, chromosome 9 at 40,187,601 bp
  • T to C, chromosome 10 at 24,654,908 bp
  • T to A, chromosome 10 at 130,389,195 bp
  • G to T, chromosome 11 at 69,946,391 bp
  • T to C, chromosome 11 at 119,039,311 bp
  • T to A, chromosome 12 at 84,613,971 bp
  • T to A, chromosome 12 at 109,594,097 bp
  • A to G, chromosome 13 at 40,918,199 bp
  • A to G, chromosome 13 at 64,787,955 bp
  • C to A, chromosome 13 at 93,045,866 bp
  • T to C, chromosome 14 at 49,960,623 bp
  • A to T, chromosome 14 at 52,174,144 bp
  • T to C, chromosome 14 at 55,677,234 bp
  • A to G, chromosome 14 at 67,705,629 bp
  • A to G, chromosome 14 at 84,446,360 bp
  • G to A, chromosome 15 at 79,712,174 bp
  • C to T, chromosome 17 at 71,244,803 bp
  • T to G, chromosome 18 at 15,063,516 bp
  • A to G, chromosome 19 at 5,136,791 bp
  • A to G, chromosome 19 at 42,076,117 bp
  • A to T, chromosome Y at 6,916,501 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5695 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043326-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.