Strain Name:
C57BL/6J-MtgxR5707Btlr/Mmmh
Stock Number:
043332-MU
Citation ID:
RRID:MMRRC_043332-MU
Other Names:
R5707 (G1)
Major Collection:

Gene Information

Sptbn1
Name: spectrin beta, non-erythrocytic 1
Synonyms: beta fodrin, Spnb-2, spectrin G, brain spectrin, elf3, elf1, 9930031C03Rik, non-erythrocytic, Spnb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20742
Homologene: 2354
Mtmr7
Name: myotubularin related protein 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 54384
HGNC: HGNC:7454
Homologene: 99732
Tanc1
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Synonyms: 1200003E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66860
Homologene: 18946
Phf20
Name: PHD finger protein 20
Synonyms: 6820402O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228829
Homologene: 9507
Pdlim5
Name: PDZ and LIM domain 5
Synonyms: Enh3, Enh2, Enh, 1110001A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 56376
Homologene: 21289
Reps1
Name: RalBP1 associated Eps domain containing protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 19707
Homologene: 7515
Cenpc1
Name: centromere protein C1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12617
HGNC: HGNC:1854
Homologene: 1371
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, Bruce, A430032G04Rik, D630005A10Rik, A430040A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Dop1a
Name: DOP1 leucine zipper like protein A
Synonyms: B130005I07Rik, D9Ertd809e, Dopey1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 320615
Homologene: 26645
Tenm2
Name: teneurin transmembrane protein 2
Synonyms: Ten-m2, D3Bwg1534e, 9330187F13Rik, 2610040L17Rik, Odz2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 23964
Homologene: 22672
Ucn3
Name: urocortin 3
Synonyms: Urocortin III
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 83428
VEGA: 13
Homologene: 49959
Cnr1
Name: cannabinoid receptor 1 (brain)
Synonyms: CB1, CB1R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12801
HGNC: HGNC:2159
Homologene: 7273
Ppp4r3a
Name: protein phosphatase 4 regulatory subunit 3A
Synonyms: 1110034C04Rik, Smek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68734
VEGA: 12
Homologene: 69510
Gm5121
Name: predicted gene 5121
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 101154638
VEGA: 9
Kirrel3
Name: kirre like nephrin family adhesion molecule 3
Synonyms: Neph2, 1500010O20Rik, 2900036G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 67703
Homologene: 57050
Klf5
Name: Kruppel-like factor 5
Synonyms: Bteb2, 4930520J07Rik, IKLF, CKLF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12224
VEGA: 14
HGNC: HGNC:6349
Homologene: 37520
Zfp507
Name: zinc finger protein 507
Synonyms: A230056M16Rik, 1810022O10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 668501
Homologene: 8942
Tmem64
Name: transmembrane protein 64
Synonyms: 9630015D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100201
Homologene: 45636
Rasgef1b
Name: RasGEF domain family, member 1B
Synonyms: Gpig4, 4732452O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 320292
Homologene: 14860
Krt14
Name: keratin 14
Synonyms: epidermolysis bullosa simplex, Dowling-Meara, Koebner, Krt-1.14, K14, Cytokeratin 14, Krt1-14
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16664
HGNC: HGNC:6416
Homologene: 110439
Aqp11
Name: aquaporin 11
Synonyms: 1700015P13Rik, sjds
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66333
Homologene: 18269
1700125H20Rik
Name: RIKEN cDNA 1700125H20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 73634
Homologene: 18763
Abca13
Name: ATP-binding cassette, sub-family A (ABC1), member 13
Synonyms: A930002G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268379
Homologene: 27991
Tarbp1
Name: TAR RNA binding protein 1
Synonyms: Gm17296
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212728
Homologene: 38082
Mroh7
Name: maestro heat-like repeat family member 7
Synonyms: LOC381538, Gm1027, Heatr8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 381538
Homologene: 19633
Kidins220
Name: kinase D-interacting substrate 220
Synonyms: 3110039L19Rik, C330002I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 77480
VEGA: 12
Homologene: 14254
Pter
Name: phosphotriesterase related
Synonyms: Mpr56-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 19212
HGNC: HGNC:9590
Homologene: 7495
Pdzd8
Name: PDZ domain containing 8
Synonyms: A630041P07Rik, Pdzk8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107368
VEGA: 19
Homologene: 14879
Xylt1
Name: xylosyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233781
Homologene: 32534
Slc4a5
Name: solute carrier family 4, sodium bicarbonate cotransporter, member 5
Synonyms: C330016K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232156
Homologene: 31125
Gm5114
Name: predicted gene 5114
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330513
Homologene: 45597
Arhgef15
Name: Rho guanine nucleotide exchange factor (GEF) 15
Synonyms: D530030K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 442801
Homologene: 18345
Diras1
Name: DIRAS family, GTP-binding RAS-like 1
Synonyms: GBTS1, Di-Ras1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 208666
Homologene: 64823
Odad4
Name: outer dynein arm complex subunit 4
Synonyms: 4933404O19Rik, Ttc25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74407
Homologene: 12860
Nhsl1
Name: NHS-like 1
Synonyms: A630035H13Rik, D10Bwg0940e, 5730409E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215819
Homologene: 27834
Elapor2
Name: endosome-lysosome associated apoptosis and autophagy regulator family member 2
Synonyms: 9330182L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231014
Homologene: 27396
Dpy19l1
Name: dpy-19-like 1 (C. elegans)
Synonyms: 1100001I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244745
Homologene: 14762
Stkld1
Name: serine/threonine kinase-like domain containing 1
Synonyms: LOC279029, Gm711
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 279029
Homologene: 19586
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215772
Homologene: 100289
Smgc
Name: submandibular gland protein C
Synonyms: Sfc21, 2310010P21Rik, DXImx49e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223809
Ctnnb1
Name: catenin (cadherin associated protein), beta 1
Synonyms: beta-catenin, Catnb, beta catenin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12387
HGNC: HGNC:2514
Homologene: 1434
Vmn2r83
Name: vomeronasal 2, receptor 83
Synonyms: EG625029
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 625029
Homologene: 83669
Ppp1r18
Name: protein phosphatase 1, regulatory subunit 18
Synonyms: 2310014H01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 76448
Homologene: 19512
Wdr90
Name: WD repeat domain 90
Synonyms: 3230401M21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106618
Homologene: 27066
Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Synonyms: Cav2.3, Cchra1, alpha1E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12290
HGNC: HGNC:1392
Homologene: 20185
Col6a2
Name: collagen, type VI, alpha 2
Synonyms: Col6a-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 12834
HGNC: HGNC:2212
Homologene: 1392
Meiob
Name: meiosis specific with OB domains
Synonyms: 4930528F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 75178
VEGA: 17
Homologene: 102013
Adcy6
Name: adenylate cyclase 6
Synonyms: AC6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11512
VEGA: 15
HGNC: HGNC:237
Homologene: 22400
Olfr382
Name: olfactory receptor 382
Synonyms: GA_x6K02T2P1NL-3676608-3675670, MOR135-14, MOR135-31_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258435
Homologene: 17252
Dydc2
Name: DPY30 domain containing 2
Synonyms: 4933428D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 71200
VEGA: 14
Homologene: 49996
Pcare
Name: photoreceptor cilium actin regulator
Synonyms: BC027072
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225004
VEGA: 17
Homologene: 19792
Ggt1
Name: gamma-glutamyltransferase 1
Synonyms: GGT, CD224, Ggtp, dwg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14598
HGNC: HGNC:4250
Homologene: 68450
Prss41
Name: protease, serine 41
Synonyms: Tessp1, 4931440B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71003
Homologene: 28091
Try4
Name: trypsin 4
Synonyms: Td, 0910001B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 22074
HGNC: HGNC:9486
Homologene: 106639
Olfr366
Name: olfactory receptor 366
Synonyms: GA_x6K02T2NLDC-33902472-33903401, MOR138-5P, MOR138-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 236509
Homologene: 114744
Cela3b
Name: chymotrypsin-like elastase family, member 3B
Synonyms: 2310074F01Rik, 0910001F22Rik, Ela3, Ela3b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 67868
Homologene: 128227
Olfr1360
Name: olfactory receptor 1360
Synonyms: GA_x6K02T2QHY8-11561962-11562903, MOR256-10, MOR256-35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 258536
Homologene: 11056
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 154,633,717 bp
  • T to C, chromosome 2 at 12,978,180 bp
  • A to G, chromosome 2 at 26,943,987 bp
  • C to A, chromosome 2 at 37,219,889 bp
  • T to C, chromosome 2 at 59,758,530 bp
  • T to G, chromosome 2 at 156,296,771 bp
  • T to A, chromosome 3 at 142,304,299 bp
  • T to C, chromosome 4 at 15,266,288 bp
  • C to A, chromosome 4 at 33,944,330 bp
  • T to A, chromosome 4 at 106,681,885 bp
  • G to T, chromosome 4 at 137,424,856 bp
  • A to G, chromosome 5 at 9,441,698 bp
  • T to A, chromosome 5 at 86,035,434 bp
  • T to G, chromosome 5 at 99,234,602 bp
  • T to C, chromosome 6 at 41,305,043 bp
  • T to A, chromosome 6 at 83,261,415 bp
  • G to T, chromosome 7 at 35,794,163 bp
  • G to C, chromosome 7 at 39,411,276 bp
  • A to G, chromosome 7 at 97,737,428 bp
  • T to A, chromosome 7 at 117,656,494 bp
  • T to C, chromosome 8 at 40,558,162 bp
  • A to G, chromosome 8 at 126,467,144 bp
  • T to C, chromosome 9 at 24,414,267 bp
  • A to G, chromosome 9 at 35,013,276 bp
  • T to G, chromosome 9 at 57,334,483 bp
  • T to A, chromosome 9 at 86,502,997 bp
  • C to A, chromosome 9 at 120,955,168 bp
  • C to T, chromosome 10 at 10,391,757 bp
  • T to A, chromosome 10 at 18,056,010 bp
  • C to T, chromosome 10 at 18,526,503 bp
  • T to A, chromosome 10 at 75,585,238 bp
  • T to C, chromosome 10 at 76,611,031 bp
  • T to A, chromosome 10 at 79,491,349 bp
  • T to C, chromosome 10 at 81,022,081 bp
  • T to C, chromosome 11 at 9,510,620 bp
  • A to T, chromosome 11 at 30,143,174 bp
  • T to C, chromosome 11 at 36,047,182 bp
  • A to G, chromosome 11 at 68,954,715 bp
  • G to T, chromosome 11 at 73,516,625 bp
  • A to G, chromosome 11 at 85,173,312 bp
  • C to T, chromosome 11 at 100,204,758 bp
  • G to A, chromosome 11 at 100,554,061 bp
  • A to G, chromosome 12 at 25,013,391 bp
  • G to A, chromosome 12 at 101,058,511 bp
  • A to G, chromosome 13 at 3,941,556 bp
  • A to G, chromosome 13 at 21,674,599 bp
  • T to G, chromosome 14 at 41,061,954 bp
  • T to C, chromosome 14 at 99,301,508 bp
  • C to T, chromosome 15 at 76,199,671 bp
  • A to T, chromosome 15 at 91,860,663 bp
  • T to C, chromosome 15 at 98,598,741 bp
  • C to T, chromosome 17 at 23,842,416 bp
  • A to G, chromosome 17 at 24,835,051 bp
  • A to G, chromosome 17 at 25,857,192 bp
  • T to C, chromosome 17 at 35,867,236 bp
  • G to T, chromosome 17 at 71,751,572 bp
  • T to A, chromosome 17 at 74,696,404 bp
  • A to T, chromosome 19 at 59,299,625 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5707 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043332-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.