Strain Name:
C57BL/6J-MtgxR5713Btlr
Stock Number:
043335-MU
Citation ID:
RRID:MMRRC_043335-MU
Other Names:
R5713 (G1)
Major Collection:

Gene Information

Bmp6
Name: bone morphogenetic protein 6
Synonyms: D13Wsu115e, Vgr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 12161
VEGA: 13
HGNC: HGNC:1073
Homologene: 1300
Pax4
Name: paired box 4
Synonyms: Pax-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 18506
HGNC: HGNC:8618
Homologene: 4515
Btbd11
Name: BTB (POZ) domain containing 11
Synonyms: 6330404E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 74007
Homologene: 72536
Jak2
Name: Janus kinase 2
Synonyms: C81284
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 16452
VEGA: 19
HGNC: HGNC:6192
Homologene: 21033
Phf20l1
Name: PHD finger protein 20-like 1
Synonyms: CGI-72, E130113K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239510
VEGA: 15
Homologene: 9341
Tcf12
Name: transcription factor 12
Synonyms: HEB, REB, HTF4, HEBAlt, ALF1, ME1, bHLHb20, HTF-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21406
Homologene: 40774
Nasp
Name: nuclear autoantigenic sperm protein (histone-binding)
Synonyms: 5033430J04Rik, Epcs32, Nasp-T, D4Ertd767e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 50927
HGNC: HGNC:7644
Homologene: 133894
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: Murr2, A530081C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17847
Homologene: 40978
Arid1b
Name: AT rich interactive domain 1B (SWI-like)
Synonyms: 9330189K18Rik, B230217J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 239985
Homologene: 32344
Casp3
Name: caspase 3
Synonyms: A830040C14Rik, AC-3, CC3, CPP32, Caspase-3, Yama, Apopain, mldy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12367
HGNC: HGNC:1504
Homologene: 37912
Lmnb2
Name: lamin B2
Synonyms: lamin B3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16907
HGNC: HGNC:6638
Homologene: 7818
Mllt3
Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
Synonyms: 2610012I03Rik, D4Ertd321e, Af9, 2210011H10Rik, 3830408D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 70122
HGNC: HGNC:7136
Homologene: 37933
Atp5g3
Name: ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228033
HGNC: HGNC:843
Homologene: 133873
Ing5
Name: inhibitor of growth family, member 5
Synonyms: 1700027H23Rik, 1810018M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 66262
Homologene: 90955
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: 2210407G14Rik, Hapip, E530005C20Rik, LOC224126
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Zfp874a
Name: zinc finger protein 874a
Synonyms: Rslcan15, C330011K17Rik, Zfp874
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 238692
Homologene: 135597
Siglecg
Name: sialic acid binding Ig-like lectin G
Synonyms: mSiglec-G, A630096C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243958
Homologene: 13228
Pla2g7
Name: phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
Synonyms: PAF acetylhydrolase, PAF-AH
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 27226
HGNC: HGNC:9040
Homologene: 3725
Serpind1
Name: serine (or cysteine) peptidase inhibitor, clade D, member 1
Synonyms: Hcf2, heparin cofactor II, HC II, HCII
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 15160
HGNC: HGNC:4838
Homologene: 36018
Pde4a
Name: phosphodiesterase 4A, cAMP specific
Synonyms: Dpde2, D9Ertd60e, dunce
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 18577
HGNC: HGNC:8780
Homologene: 4520
Nr1d1
Name: nuclear receptor subfamily 1, group D, member 1
Synonyms: A530070C09Rik, rev-erbA(alpha), REV-ERBalpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217166
HGNC: HGNC:7962
Homologene: 23324
Cdc42bpa
Name: CDC42 binding protein kinase alpha
Synonyms: A930014J19Rik, DMPK-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226751
HGNC: HGNC:1737
Homologene: 55765
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Hc
Name: hemolytic complement
Synonyms: C5, C5a, Hfib2, He
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Mtpap
Name: mitochondrial poly(A) polymerase
Synonyms: 0610027A18Rik, Papd1, Tent6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 67440
VEGA: 18
Homologene: 10008
Plcb3
Name: phospholipase C, beta 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 18797
VEGA: 19
HGNC: HGNC:9056
Homologene: 47960
Abhd18
Name: abhydrolase domain containing 18
Synonyms: 3110057O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 269423
Homologene: 105457
Lipa
Name: lysosomal acid lipase A
Synonyms: Lal, Lip-1, Lip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 16889
VEGA: 19
HGNC: HGNC:6617
Homologene: 37277
Supv3l1
Name: suppressor of var1, 3-like 1 (S. cerevisiae)
Synonyms: 6330443E10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 338359
Homologene: 2386
Vmn2r108
Name: vomeronasal 2, receptor 108
Synonyms: EG627805
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 627805
Homologene: 129678
Otop2
Name: otopetrin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237987
Homologene: 27803
Clic3
Name: chloride intracellular channel 3
Synonyms: 2300003G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 69454
HGNC: HGNC:2064
Homologene: 3432
Rbm24
Name: RNA binding motif protein 24
Synonyms: 6330546B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 666794
VEGA: 13
Homologene: 23015
Ccl3
Name: chemokine (C-C motif) ligand 3
Synonyms: MIP1-alpha, Mip1a, macrophage inflammatory protein-1alpha, MIP-1alpha, MIP-1 alpha, Scya3, LD78alpha, G0S19-1, CCL3, MIP1-(a)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20302
Homologene: 2242
Il2rb
Name: interleukin 2 receptor, beta chain
Synonyms: CD122, IL-15Rbeta, IL15Rbeta, IL-2/15Rbeta, IL-15 receptor beta chain, Il-2Rbeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 16185
VEGA: 15
HGNC: HGNC:6009
Homologene: 47955
Mup21
Name: major urinary protein 21
Synonyms: Gm11208
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381531
Homologene: 74304
Aqp7
Name: aquaporin 7
Synonyms: AQP7L, AQPap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11832
HGNC: HGNC:640
Homologene: 48000
Slc26a8
Name: solute carrier family 26, member 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224661
Homologene: 27095
Prr16
Name: proline rich 16
Synonyms: 5430406M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 71373
VEGA: 18
Homologene: 41152
Tcrg-C2
Name: T-cell receptor gamma, constant 2
Synonyms: Tcrg-C2, Gm16603, Trgc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 107574
Gm4887
Name: predicted gene 4887
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233637
Homologene: 131294
Gm26627
Name: predicted gene, 26627
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 105242612
Rps29
Name: ribosomal protein S29
Synonyms: S29 ribosomal protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20090
Homologene: 83197
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 93,812,730 bp
  • T to C, chromosome 1 at 180,084,410 bp
  • A to T, chromosome 2 at 25,458,167 bp
  • A to C, chromosome 2 at 35,013,531 bp
  • A to G, chromosome 2 at 73,909,307 bp
  • T to A, chromosome 3 at 40,934,979 bp
  • G to A, chromosome 4 at 41,035,510 bp
  • C to G, chromosome 4 at 62,150,274 bp
  • A to T, chromosome 4 at 87,841,211 bp
  • A to G, chromosome 4 at 116,614,361 bp
  • A to G, chromosome 6 at 28,446,185 bp
  • A to G, chromosome 6 at 29,507,851 bp
  • A to T, chromosome 7 at 43,408,802 bp
  • A to T, chromosome 7 at 104,821,793 bp
  • C to A, chromosome 8 at 46,636,314 bp
  • T to A, chromosome 9 at 21,203,517 bp
  • T to C, chromosome 9 at 71,885,263 bp
  • A to G, chromosome 10 at 62,430,504 bp
  • C to T, chromosome 10 at 80,906,087 bp
  • A to T, chromosome 10 at 85,651,652 bp
  • T to A, chromosome 11 at 23,343,515 bp
  • T to A, chromosome 11 at 66,025,223 bp
  • C to T, chromosome 11 at 83,649,240 bp
  • T to C, chromosome 11 at 98,770,411 bp
  • T to A, chromosome 11 at 115,329,044 bp
  • C to A, chromosome 12 at 69,158,728 bp
  • T to A, chromosome 13 at 19,307,345 bp
  • C to T, chromosome 13 at 38,498,952 bp
  • A to G, chromosome 13 at 46,429,304 bp
  • A to T, chromosome 13 at 67,449,357 bp
  • A to G, chromosome 15 at 66,636,820 bp
  • A to G, chromosome 15 at 78,491,848 bp
  • A to G, chromosome 16 at 17,336,987 bp
  • A to T, chromosome 16 at 34,016,579 bp
  • C to A, chromosome 17 at 5,336,816 bp
  • A to G, chromosome 17 at 20,471,028 bp
  • T to A, chromosome 17 at 28,661,879 bp
  • T to A, chromosome 17 at 43,594,292 bp
  • G to A, chromosome 18 at 4,396,280 bp
  • A to G, chromosome 18 at 51,302,838 bp
  • T to C, chromosome 19 at 6,957,692 bp
  • A to G, chromosome 19 at 29,271,393 bp
  • A to T, chromosome 19 at 34,523,432 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5713 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043335-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.