Loading Mouse GIF
Loading...

Strain Name:
C57BL/6J-MtgxR5719Btlr/Mmmh
Stock Number:
043339-MU
Citation ID:
RRID:MMRRC_043339-MU
Other Names:
R5719 (G1)
Major Collection:

Strain Information

Myo5a
Name: myosin VA
Synonyms: MVa, MyoVA, Myo5, flail, 9630007J19Rik, Dbv
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17918
HGNC: HGNC:7602
Homologene: 20100
Crhr2
Name: corticotropin releasing hormone receptor 2
Synonyms: Crfr2, CRF-R2, CRFR2beta, CRFR2alpha, CRF 2 receptor, CRH-R2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12922
HGNC: HGNC:2358
Homologene: 55612
Herc3
Name: hect domain and RLD 3
Synonyms: 5730409F18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 73998
HGNC: HGNC:4876
Homologene: 57095
Dnmt1
Name: DNA methyltransferase 1
Synonyms: MTase, Dnmt1o, Cxxc9, MommeD2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 13433
VEGA: 9
HGNC: HGNC:2976
Homologene: 124071
Tmem248
Name: transmembrane protein 248
Synonyms: G430067H08Rik, A930023A16Rik, 0610007L01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71667
Homologene: 9951
Zranb3
Name: zinc finger, RAN-binding domain containing 3
Synonyms: 4933425L19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226409
Homologene: 32770
Cdk13
Name: cyclin dependent kinase 13
Synonyms: 2310015O17Rik, Cdc2l5
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69562
VEGA: 13
HGNC: HGNC:1733
Homologene: 135707
Shroom3
Name: shroom family member 3
Synonyms: D5Ertd287e, Shrm, Shrm3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 27428
Homologene: 9263
Ccdc91
Name: coiled-coil domain containing 91
Synonyms: 1700086G08Rik, 1810060J02Rik, p56
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67015
Homologene: 10131
Top3b
Name: topoisomerase (DNA) III beta
Synonyms: Topo III beta
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 21976
Homologene: 2923
Schip1
Name: schwannomin interacting protein 1
Synonyms: SCHIP-1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 30953
Homologene: 130673
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: A530081C03Rik, Murr2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17847
Homologene: 40978
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: chromatin remodeling factor, 8030453L17Rik, E430018P19Rik, KMT2H
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192195
Homologene: 10225
Slc22a3
Name: solute carrier family 22 (organic cation transporter), member 3
Synonyms: EMT, Oct3, Orct3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20519
VEGA: 17
Homologene: 22630
Eif4g1
Name: eukaryotic translation initiation factor 4, gamma 1
Synonyms: E030015G23Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208643
HGNC: HGNC:3296
Homologene: 110725
Osbpl9
Name: oxysterol binding protein-like 9
Synonyms: 2600011I06Rik, ORP-9
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100273
Homologene: 69380
Zbtb2
Name: zinc finger and BTB domain containing 2
Synonyms: LOC381990
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 381990
VEGA: 10
Homologene: 10837
Gfral
Name: GDNF family receptor alpha like
Synonyms: GRAL
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 404194
Homologene: 45748
Lsg1
Name: large 60S subunit nuclear export GTPase 1
Synonyms: D16Bwg1547e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224092
Homologene: 5917
Snf8
Name: SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)
Synonyms: D11Moh34
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 27681
Homologene: 5239
Eml2
Name: echinoderm microtubule associated protein like 2
Synonyms: 1600029N02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72205
Homologene: 8125
N4bp1
Name: NEDD4 binding protein 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 80750
Homologene: 23703
Slc7a5
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
Synonyms: TA1, D0H16S474E, LAT1, Gm42049
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 20539
Homologene: 55759
Kcng3
Name: potassium voltage-gated channel, subfamily G, member 3
Synonyms: KV6.3, Kv10.1b, Kv10.1a
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 225030
VEGA: 17
Homologene: 15168
Ccdc127
Name: coiled-coil domain containing 127
Synonyms: 5430420E17Rik, 0610011N22Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67433
Homologene: 11482
Cacna2d2
Name: calcium channel, voltage-dependent, alpha 2/delta subunit 2
Synonyms: a2d2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 56808
HGNC: HGNC:1400
Homologene: 4400
Tmprss7
Name: transmembrane serine protease 7
Synonyms: LOC385645, B230219I23Rik, matriptase-3
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208171
Homologene: 18178
Fyb1
Name: FYN binding protein 1
Synonyms: FYB-120/130, ADAP, B630013F22Rik, Fyb
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 23880
HGNC: HGNC:4036
Homologene: 22664
Ptprd
Name: protein tyrosine phosphatase receptor type D
Synonyms: 3000002J10Rik, B230219D21Rik, 1110002J03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19266
HGNC: HGNC:9668
Abca4
Name: ATP-binding cassette, sub-family A member 4
Synonyms: Rim protein, RmP, Abc10, D430003I15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11304
HGNC: HGNC:34
Homologene: 298
Nuak1
Name: NUAK family, SNF1-like kinase, 1
Synonyms: B230104P22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 77976
Homologene: 8896
Bltp2
Name: bridge-like lipid transfer protein family member 2
Synonyms: 2610507B11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72503
Homologene: 34730
Wdr24
Name: WD repeat domain 24
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268933
Homologene: 6870
Actrt3
Name: actin related protein T3
Synonyms: 1700119I24Rik, Arpm1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76652
Homologene: 13038
Scn5a
Name: sodium channel, voltage-gated, type V, alpha
Synonyms: Nav1.5c, Nav1.5, mH1, SkM2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20271
Homologene: 22738
Ppargc1b
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 beta
Synonyms: PGC-1beta/ERRL1, 4631412G21Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 170826
Homologene: 15776
Odad2
Name: outer dynein arm docking complex subunit 2
Synonyms: 4930463I21Rik, Armc4, b2b227.1Clo, b2b643Clo
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 74934
VEGA: 18
Homologene: 9992
Nlrc3
Name: NLR family, CARD domain containing 3
Synonyms: D230007K08Rik, Caterpiller 16.2, CLR16.2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 268857
Homologene: 18720
Stox2
Name: storkhead box 2
Synonyms: 4933409N07Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71069
Homologene: 18414
Smc1b
Name: structural maintenance of chromosomes 1B
Synonyms: SMC1beta, Smc1l2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 140557
VEGA: 15
Homologene: 13786
Greb1l
Name: growth regulation by estrogen in breast cancer-like
Synonyms: mKIAA4095, AK220484
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 381157
Homologene: 73393
Tsen15
Name: tRNA splicing endonuclease subunit 15
Synonyms: 5730449L18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66637
Homologene: 12002
Slc14a2
Name: solute carrier family 14 (urea transporter), member 2
Synonyms: UT-A3, UT-A5
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 27411
VEGA: 18
Homologene: 5183
Adam22
Name: a disintegrin and metallopeptidase domain 22
Synonyms: MDC2, 2900022I03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11496
HGNC: HGNC:201
Homologene: 37898
Abcc3
Name: ATP-binding cassette, sub-family C member 3
Synonyms: 1700019L09Rik, MRP3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76408
HGNC: HGNC:54
Homologene: 68364
Or5w11
Name: olfactory receptor family 5 subfamily W member 11
Synonyms: GA_x6K02T2Q125-49133664-49134593, MOR177-4, Olfr1131
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258652
Homologene: 133019
Fam234a
Name: family with sequence similarity 234, member A
Synonyms: Itfg3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106581
Homologene: 12932
Prss40
Name: serine protease 40
Synonyms: Tesp2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 21756
Homologene: 69043
Skint8
Name: selection and upkeep of intraepithelial T cells 8
Synonyms: OTTMUSG00000009475
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 639774
Homologene: 106613
Myrf
Name: myelin regulatory factor
Synonyms: LOC225908, LOC386531, Gm98
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225908
HGNC: HGNC:1181
Homologene: 32167
Gm5501
Name: predicted gene 5501
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 433161
Krt36
Name: keratin 36
Synonyms: HRa-1, Krt1-22, keratin 5, Krt1-5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16673
HGNC: HGNC:6454
Homologene: 88459
Or5p66
Name: olfactory receptor family 5 subfamily P member 66
Synonyms: GA_x6K02T2PBJ9-10617173-10616229, MOR204-17, Olfr490
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258491
Homologene: 73955
Or8b4
Name: olfactory receptor family 8 subfamily B member 4
Synonyms: GA_x6K02T2PVTD-31600511-31601440, MOR163-1, Olfr878
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258794
HGNC: HGNC:8473
Homologene: 17395
A630001G21Rik
Name: RIKEN cDNA A630001G21 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 319997
Homologene: 79992
Rftn2
Name: raftlin family member 2
Synonyms: 2700010E02Rik, 3222401M22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74013
Homologene: 16954
Igfbp6
Name: insulin-like growth factor binding protein 6
Synonyms: IGFBP-6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16012
HGNC: HGNC:5475
Homologene: 1641
Gm9871
Name: predicted gene 9871
Synonyms: EG207157
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 207157
Krtap4-22
Name: keratin associated protein 4-22
Synonyms: Gm11595
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 100040276
Homologene: 124486
Lrwd1
Name: leucine-rich repeats and WD repeat domain containing 1
Synonyms: 1200011O22Rik, Orca
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71735
Homologene: 17678
Isyna1
Name: myo-inositol 1-phosphate synthase A1
Synonyms: 1300017C10Rik, inositol-3-phosphate synthase 1, myo-inositol 1-phosphate synthase A1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71780
Homologene: 6222
Gm10309
Name: predicted gene 10309
Type: Gene
Species: Mouse
Chromosome: 17
Gm6309
Name: predicted gene 6309
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 622306
Homologene: 86127
Ifi27l2b
Name: interferon, alpha-inducible protein 27 like 2B
Synonyms: 1810023F06Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217845
Homologene: 137395
Rnaset2a
Name: ribonuclease T2A
Synonyms: RNASE6PL, 0610007O07Rik, 4930532K22Rik, 4833423A10Rik, Rnaset2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 100037283
VEGA: 17
Homologene: 31190
Hes7
Name: hes family bHLH transcription factor 7
Synonyms: bHLHb37
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 84653
Homologene: 23779
A130051J06Rik
Name: RIKEN cDNA A130051J0 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 791370
VEGA: 15
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 34,552,517 bp
  • C to T, chromosome 1 at 55,214,286 bp
  • T to A, chromosome 1 at 85,723,385 bp
  • T to C, chromosome 1 at 127,963,876 bp
  • T to C, chromosome 1 at 152,371,783 bp
  • T to C, chromosome 2 at 87,629,131 bp
  • A to C, chromosome 3 at 30,598,127 bp
  • T to C, chromosome 3 at 68,408,227 bp
  • C to A, chromosome 3 at 89,054,498 bp
  • T to C, chromosome 3 at 89,058,626 bp
  • T to C, chromosome 3 at 122,135,266 bp
  • T to A, chromosome 4 at 76,054,602 bp
  • T to A, chromosome 4 at 109,062,566 bp
  • C to A, chromosome 4 at 111,950,193 bp
  • T to C, chromosome 5 at 8,367,217 bp
  • T to A, chromosome 5 at 92,943,018 bp
  • T to A, chromosome 5 at 130,229,588 bp
  • A to T, chromosome 5 at 136,132,239 bp
  • A to T, chromosome 5 at 146,168,182 bp
  • T to C, chromosome 6 at 55,103,222 bp
  • T to A, chromosome 6 at 58,894,543 bp
  • T to A, chromosome 6 at 101,796,187 bp
  • C to G, chromosome 6 at 147,575,503 bp
  • G to A, chromosome 7 at 19,201,163 bp
  • T to G, chromosome 7 at 108,286,392 bp
  • T to A, chromosome 8 at 47,413,137 bp
  • A to G, chromosome 8 at 70,594,702 bp
  • T to C, chromosome 8 at 86,851,684 bp
  • C to T, chromosome 8 at 95,744,296 bp
  • A to C, chromosome 8 at 121,883,642 bp
  • T to C, chromosome 9 at 20,912,595 bp
  • A to T, chromosome 9 at 37,919,351 bp
  • A to T, chromosome 9 at 75,151,931 bp
  • C to T, chromosome 9 at 76,197,046 bp
  • A to G, chromosome 9 at 107,524,652 bp
  • A to C, chromosome 9 at 119,530,052 bp
  • G to A, chromosome 10 at 4,369,456 bp
  • A to T, chromosome 10 at 84,409,720 bp
  • T to G, chromosome 11 at 23,354,846 bp
  • A to G, chromosome 11 at 69,121,589 bp
  • T to A, chromosome 11 at 78,273,245 bp
  • T to C, chromosome 11 at 94,351,068 bp
  • T to A, chromosome 11 at 96,041,725 bp
  • G to A, chromosome 11 at 99,772,555 bp
  • T to C, chromosome 11 at 100,104,161 bp
  • T to C, chromosome 12 at 103,455,787 bp
  • A to G, chromosome 13 at 17,719,655 bp
  • T to A, chromosome 13 at 74,357,068 bp
  • T to C, chromosome 14 at 30,663,226 bp
  • A to T, chromosome 15 at 6,580,869 bp
  • T to A, chromosome 15 at 85,096,658 bp
  • C to T, chromosome 15 at 95,790,760 bp
  • A to T, chromosome 15 at 102,148,181 bp
  • C to T, chromosome 16 at 3,963,725 bp
  • T to C, chromosome 16 at 16,885,836 bp
  • T to A, chromosome 16 at 20,689,011 bp
  • C to T, chromosome 16 at 30,561,775 bp
  • T to C, chromosome 16 at 45,686,430 bp
  • T to C, chromosome 17 at 8,132,047 bp
  • C to T, chromosome 17 at 12,423,804 bp
  • T to C, chromosome 17 at 25,828,340 bp
  • T to A, chromosome 17 at 26,214,653 bp
  • G to T, chromosome 17 at 83,631,134 bp
  • A to T, chromosome 17 at 86,498,993 bp
  • G to T, chromosome 18 at 7,211,496 bp
  • G to A, chromosome 18 at 9,917,417 bp
  • G to A, chromosome 18 at 10,542,427 bp
  • T to A, chromosome 18 at 61,307,568 bp
  • A to G, chromosome 18 at 78,209,042 bp
  • T to A, chromosome 19 at 10,216,723 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5719 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043339-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.