Strain Name:
C57BL/6J-MtgxR5732Btlr
Stock Number:
043347-MU
Citation ID:
RRID:MMRRC_043347-MU
Other Names:
R5732 (G1)
Major Collection:

Gene Information

Wdr47
Name: WD repeat domain 47
Synonyms: 1810073M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99512
Homologene: 8984
Dhx35
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 35
Synonyms: 1200009D07Rik, Ddx35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 71715
Homologene: 6406
Foxj3
Name: forkhead box J3
Synonyms: Fhd6, C330039G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230700
Homologene: 35243
Dctn1
Name: dynactin 1
Synonyms: Glued, p150, p150glued
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 13191
HGNC: HGNC:2711
Homologene: 3011
Dcun1d3
Name: DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
Synonyms: 1700020A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233805
Homologene: 16155
Nr3c1
Name: nuclear receptor subfamily 3, group C, member 1
Synonyms: Grl1, GR, glucocorticoid receptor, Grl-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 14815
HGNC: HGNC:7978
Homologene: 30960
Apob
Name: apolipoprotein B
Synonyms: apob-48, apob-100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Lrig1
Name: leucine-rich repeats and immunoglobulin-like domains 1
Synonyms: Img, LIG-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 16206
Homologene: 7380
Fndc3b
Name: fibronectin type III domain containing 3B
Synonyms: 1600019O04Rik, fad104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 72007
Homologene: 11244
Acsf2
Name: acyl-CoA synthetase family member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 264895
Homologene: 23519
Snrpd2
Name: small nuclear ribonucleoprotein D2
Synonyms: 1810009A06Rik, SMD2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 107686
Homologene: 3381
Zfp644
Name: zinc finger protein 644
Synonyms: BM-005, D5Ertd689e, 1110068L01Rik, Zep-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 52397
Homologene: 12971
Tbc1d32
Name: TBC1 domain family, member 32
Synonyms: Bromi, D630037F22Rik, b2b2284Clo, C6orf170
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 544696
VEGA: 10
Homologene: 51889
Uggt1
Name: UDP-glucose glycoprotein glucosyltransferase 1
Synonyms: 0910001L17Rik, A930007H10Rik, C820010P03Rik, Ugcgl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 320011
Homologene: 10586
Kat2a
Name: K(lysine) acetyltransferase 2A
Synonyms: Gcn5, Gcn5l2, PCAF-B/GCN5, 1110051E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14534
HGNC: HGNC:4201
Homologene: 41343
Gp2
Name: glycoprotein 2 (zymogen granule membrane)
Synonyms: 2310037I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67133
HGNC: HGNC:4441
Homologene: 133790
Cdh23
Name: cadherin 23 (otocadherin)
Synonyms: USH1D, mdfw, ahl, nmf112, nmf181, nmf252, 4930542A03Rik, sals, bob
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 22295
Homologene: 11142
Kcnq1
Name: potassium voltage-gated channel, subfamily Q, member 1
Synonyms: KVLQT1, Kcna9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16535
HGNC: HGNC:6294
Homologene: 85014
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hy-3, hy3, 1700034M11Rik, hyrh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244653
Homologene: 52118
Siglec1
Name: sialic acid binding Ig-like lectin 1, sialoadhesin
Synonyms: Sn, Siglec-1, CD169
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20612
Homologene: 124458
Flt1
Name: FMS-like tyrosine kinase 1
Synonyms: vascular endothelial growth factor receptor-1, VEGFR-1, Flt-1, VEGFR1, sFlt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14254
HGNC: HGNC:3763
Homologene: 134179
Letm2
Name: leucine zipper-EF-hand containing transmembrane protein 2
Synonyms: D030041N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 270035
Homologene: 56358
Tmem266
Name: transmembrane protein 266
Synonyms: AI118078
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244886
Homologene: 17551
Top2b
Name: topoisomerase (DNA) II beta
Synonyms: Top-2, D230016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 21974
Homologene: 134711
Atg2a
Name: autophagy related 2A
Synonyms: 1810013C15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 329015
Homologene: 86985
Mug1
Name: murinoglobulin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 17836
Homologene: 136663
Fam171a2
Name: family with sequence similarity 171, member A2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217219
Homologene: 19144
Tex10
Name: testis expressed gene 10
Synonyms: 2810462N03Rik, clone 18330, 2610206N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269536
Homologene: 32361
Cps1
Name: carbamoyl-phosphate synthetase 1
Synonyms: 4732433M03Rik, CPS, D1Ucla3, CPSase I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227231
HGNC: HGNC:2323
Homologene: 68208
Capn5
Name: calpain 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12337
HGNC: HGNC:1482
Homologene: 31212
Cdx2
Name: caudal type homeobox 2
Synonyms: Cdx-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12591
HGNC: HGNC:1806
Homologene: 968
Zfp687
Name: zinc finger protein 687
Synonyms: 4931408L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 78266
Homologene: 10827
Naaa
Name: N-acylethanolamine acid amidase
Synonyms: Asahl, 2210023K21Rik, 3830414F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 67111
HGNC: HGNC:736
Homologene: 8686
Cdadc1
Name: cytidine and dCMP deaminase domain containing 1
Synonyms: NYD-SP15, 2310010M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 71891
VEGA: 14
Homologene: 12794
Llgl1
Name: LLGL1 scribble cell polarity complex component
Synonyms: Lgl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16897
HGNC: HGNC:6628
Homologene: 31220
Acaa1b
Name: acetyl-Coenzyme A acyltransferase 1B
Synonyms: thiolase B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235674
HGNC: HGNC:82
Homologene: 91131
Slco2a1
Name: solute carrier organic anion transporter family, member 2a1
Synonyms: mPgt, Pgt, Slc21a2, 2310021C19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 24059
Homologene: 38077
Lrfn3
Name: leucine rich repeat and fibronectin type III domain containing 3
Synonyms: SALM4, A530045B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233067
Homologene: 11558
Ccdc152
Name: coiled-coil domain containing 152
Synonyms: ENSMUSG00000071814
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 100039139
VEGA: 15
Homologene: 79247
Slc35a4
Name: solute carrier family 35, member A4
Synonyms: 2610030J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 67843
Homologene: 12195
Slc52a2
Name: solute carrier protein 52, member 2
Synonyms: D15Ertd747e, 2010003P03Rik, Gpr172b, PAR2, GPCR42
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 52710
VEGA: 15
Homologene: 56994
Pacsin3
Name: protein kinase C and casein kinase substrate in neurons 3
Synonyms: 6330413E15Rik, 4921507A02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 80708
HGNC: HGNC:8572
Homologene: 41117
Ndufaf1
Name: NADH:ubiquinone oxidoreductase complex assembly factor 1
Synonyms: CIA30, CGI-65, 2410001M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 69702
Homologene: 32289
Nsun5
Name: NOL1/NOP2/Sun domain family, member 5
Synonyms: Wbscr20a, 9830109N13Rik, Nol1r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 100609
Homologene: 6828
Cd3g
Name: CD3 antigen, gamma polypeptide
Synonyms: Ctg3, T3g, Ctg-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 12502
HGNC: HGNC:1675
Homologene: 55
Rpgr
Name: retinitis pigmentosa GTPase regulator
Synonyms: Rp3h, Rd9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 19893
Homologene: 55455
1700008F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 36,161,771 bp
  • A to T, chromosome 1 at 67,157,764 bp
  • A to G, chromosome 2 at 91,260,260 bp
  • G to A, chromosome 2 at 119,660,040 bp
  • G to A, chromosome 2 at 131,074,268 bp
  • G to A, chromosome 2 at 158,831,785 bp
  • T to C, chromosome 3 at 27,461,773 bp
  • T to C, chromosome 3 at 95,011,217 bp
  • T to A, chromosome 3 at 108,633,156 bp
  • G to T, chromosome 4 at 48,460,046 bp
  • A to T, chromosome 4 at 119,585,811 bp
  • G to A, chromosome 5 at 92,263,455 bp
  • A to T, chromosome 5 at 106,637,123 bp
  • T to C, chromosome 5 at 135,371,350 bp
  • T to C, chromosome 5 at 147,302,023 bp
  • G to T, chromosome 5 at 147,634,483 bp
  • G to A, chromosome 6 at 83,197,949 bp
  • G to T, chromosome 6 at 94,699,539 bp
  • A to G, chromosome 6 at 121,878,493 bp
  • T to C, chromosome 7 at 19,152,613 bp
  • T to C, chromosome 7 at 30,359,606 bp
  • A to G, chromosome 7 at 98,129,386 bp
  • A to G, chromosome 7 at 119,449,108 bp
  • T to C, chromosome 7 at 119,858,033 bp
  • C to A, chromosome 7 at 143,148,756 bp
  • A to C, chromosome 8 at 25,587,325 bp
  • T to A, chromosome 8 at 110,452,058 bp
  • A to G, chromosome 8 at 129,072,714 bp
  • T to C, chromosome 9 at 44,973,631 bp
  • T to C, chromosome 9 at 55,380,836 bp
  • C to T, chromosome 9 at 103,050,256 bp
  • T to A, chromosome 9 at 119,148,394 bp
  • T to A, chromosome 10 at 56,088,393 bp
  • A to G, chromosome 10 at 60,331,317 bp
  • T to C, chromosome 11 at 60,709,460 bp
  • T to C, chromosome 11 at 94,569,942 bp
  • A to G, chromosome 11 at 100,708,240 bp
  • T to C, chromosome 11 at 102,439,981 bp
  • A to G, chromosome 12 at 8,010,353 bp
  • A to T, chromosome 14 at 16,400,106 bp
  • A to G, chromosome 14 at 59,596,911 bp
  • A to G, chromosome 15 at 3,292,378 bp
  • T to C, chromosome 15 at 76,541,074 bp
  • A to T, chromosome 18 at 36,682,341 bp
  • A to T, chromosome 18 at 39,415,699 bp
  • T to C, chromosome 19 at 6,257,460 bp
  • G to A, chromosome X at 10,166,272 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5732 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043347-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.