Strain Name:
C57BL/6J-MtgxR5734Btlr
Stock Number:
043348-MU
Citation ID:
RRID:MMRRC_043348-MU
Other Names:
R5734 (G1)
Major Collection:

Gene Information

Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: TM7LN3, EGF-TM7, F4/80, DD7A5-7, Emr1, Ly71
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Marc2
Name: mitochondrial amidoxime reducing component 2
Synonyms: Mosc2, 2810484M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 67247
Homologene: 9904
Arid4b
Name: AT rich interactive domain 4B (RBP1-like)
Synonyms: 6720480E17Rik, RBBP1L1, Rbp1l1, SAP180, 6330417L24Rik, BRCAA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 94246
Homologene: 12847
Usp7
Name: ubiquitin specific peptidase 7
Synonyms: 2210010O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 252870
Homologene: 2592
Ccn1
Name: cellular communication network factor 1
Synonyms: Cyr61, CCN1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 16007
HGNC: HGNC:2654
Homologene: 1194
Lactb2
Name: lactamase, beta 2
Synonyms: E430032H21Rik, Cgi-83
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 212442
Homologene: 9349
Kat8
Name: K(lysine) acetyltransferase 8
Synonyms: MOF, 5830450F21Rik, Myst1, D7Ertd629e, 2010203C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67773
Homologene: 41676
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: apollon, D630005A10Rik, A430040A19Rik, Bruce, A430032G04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12211
Homologene: 7248
Relch
Name: RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
Synonyms: 2310035C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227446
Homologene: 10834
Dcaf8
Name: DDB1 and CUL4 associated factor 8
Synonyms: D1Dau35e, D1Ucla4, Wdr42a, H326
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 98193
Homologene: 56725
Skp2
Name: S-phase kinase-associated protein 2 (p45)
Synonyms: FBXL1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 27401
Homologene: 55942
Rbm34
Name: RNA binding motif protein 34
Synonyms: D8Ertd233e, 4930547K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 52202
Homologene: 56691
Capza2
Name: capping protein (actin filament) muscle Z-line, alpha 2
Synonyms: 1110053K06Rik, Cappa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12343
HGNC: HGNC:1490
Homologene: 55956
Robo2
Name: roundabout guidance receptor 2
Synonyms: 2600013A04Rik, 9430089E08Rik, D230004I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 268902
Homologene: 43188
Apob
Name: apolipoprotein B
Synonyms: apob-48, apob-100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Smad5
Name: SMAD family member 5
Synonyms: Smad 5, MusMLP, Madh5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17129
HGNC: HGNC:6771
Homologene: 4313
Nop53
Name: NOP53 ribosome biogenesis factor
Synonyms: 9430097C02Rik, Gltscr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 68077
HGNC: HGNC:4333
Homologene: 44130
St3gal1
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 1
Synonyms: Siat4, CMP-N-acetylneuraminate: [beta-galactosidase alpha-2,3] sialytransferase, ST3GalI, Siat4a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20442
VEGA: 15
Homologene: 7540
Chrm5
Name: cholinergic receptor, muscarinic 5
Synonyms: muscarinic acetylcholine receptor 5, M5R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 213788
HGNC: HGNC:1954
Homologene: 22697
Cacna1a
Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Synonyms: smrl, alpha1A, Cacnl1a4, SCA6, nmf352, Ccha1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12286
HGNC: HGNC:1388
Homologene: 56383
Sox6
Name: SRY (sex determining region Y)-box 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 20679
Homologene: 22631
Tex15
Name: testis expressed gene 15
Synonyms: 2210014E14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 104271
Homologene: 12837
Sorcs1
Name: sortilin-related VPS10 domain containing receptor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 58178
Homologene: 10967
Ccdc125
Name: coiled-coil domain containing 125
Synonyms: 5830436D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 76041
VEGA: 13
Homologene: 27932
Nlrp9a
Name: NLR family, pyrin domain containing 9A
Synonyms: D7Ertd565e, Nalp9a, Nalp-theta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233001
HGNC: null
Homologene: 116072
Scn2a
Name: sodium channel, voltage-gated, type II, alpha
Synonyms: Nav1.2, A230052E19Rik, Scn2a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 110876
Homologene: 75001
Nek9
Name: NIMA (never in mitosis gene a)-related expressed kinase 9
Synonyms: C130021H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217718
Homologene: 13222
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 81877
Homologene: 49589
Adamts2
Name: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
Synonyms: procollagen N-proteinase, hPCPNI, ADAM-TS2, a disintegrin and metalloproteinase with thrombospondin repeats
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216725
HGNC: HGNC:218
Homologene: 8597
Abcc9
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Synonyms: SUR2A, SUR2B, Sur2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Ttc21a
Name: tetratricopeptide repeat domain 21A
Synonyms: 4921538N17Rik, Thm2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74052
Homologene: 14728
Trpm8
Name: transient receptor potential cation channel, subfamily M, member 8
Synonyms: CMR1, Trp-p8, TRPP8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 171382
Homologene: 23433
4931429L15Rik
Name: RIKEN cDNA 4931429L15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74361
HGNC: null
Homologene: 86847
Zfp217
Name: zinc finger protein 217
Synonyms: 4933431C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228913
Homologene: 4757
Glipr1
Name: GLI pathogenesis-related 1 (glioma)
Synonyms: RTVP-1, RTVP1, 2410114O14Rik, mRTVP-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 73690
Homologene: 21357
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: Opo, ojoplano
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218165
VEGA: 13
Homologene: 125376
Myoz3
Name: myozenin 3
Synonyms: calsarcin-3, Fatz-3, 4833419K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 170947
Homologene: 15782
Clip1
Name: CAP-GLY domain containing linker protein 1
Synonyms: cytoplasmic linker protein 50, Rsn, 1110007I12Rik, CLIP-170, Clip 170, 4631429H07Rik, Clip50, restin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 56430
Homologene: 74455
Capn9
Name: calpain 9
Synonyms: GC36, nCL-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 73647
HGNC: HGNC:1486
Homologene: 38208
Asb3
Name: ankyrin repeat and SOCS box-containing 3
Synonyms: 2400011J03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 65257
Homologene: 9391
Dbx2
Name: developing brain homeobox 2
Synonyms: 9430056A22Rik, LOC383001
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223843
Homologene: 54981
Lin28a
Name: lin-28 homolog A (C. elegans)
Synonyms: Tex17, Lin-28, Lin28, Lin28a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 83557
Homologene: 32592
Pabpc4l
Name: poly(A) binding protein, cytoplasmic 4-like
Synonyms: C330050A14Rik, EG241989
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 241989
Homologene: 66336
Zfp382
Name: zinc finger protein 382
Synonyms: 5930415A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233060
Homologene: 32798
Trat1
Name: T cell receptor associated transmembrane adaptor 1
Synonyms: C030046M14Rik, Trim, Tcrim
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 77647
VEGA: 16
Homologene: 41130
Fam114a1
Name: family with sequence similarity 114, member A1
Synonyms: 9130005N14Rik, 1190001N04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 68303
Homologene: 12259
Gpt2
Name: glutamic pyruvate transaminase (alanine aminotransferase) 2
Synonyms: ALT2, 4631422C05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 108682
Homologene: 68832
Selp
Name: selectin, platelet
Synonyms: P-selectin, CD62P, Grmp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 20344
Homologene: 2260
Chtop
Name: chromatin target of PRMT1
Synonyms: 2500003M10Rik, friend of Prmt1, Fop
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66511
Homologene: 137362
Tpbgl
Name: trophoblast glycoprotein-like
Synonyms: Gm4980
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100503386
Homologene: 47844
Rpgr
Name: retinitis pigmentosa GTPase regulator
Synonyms: Rp3h, Rd9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 19893
Homologene: 55455
Gm6408
Name: predicted gene 6408
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 623198
HGNC: null
Homologene: 86127
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 13,660,387 bp
  • T to A, chromosome 1 at 88,355,280 bp
  • T to C, chromosome 1 at 105,703,883 bp
  • C to T, chromosome 1 at 164,143,891 bp
  • T to C, chromosome 1 at 172,172,911 bp
  • T to C, chromosome 1 at 184,832,589 bp
  • A to G, chromosome 2 at 65,717,722 bp
  • T to A, chromosome 2 at 112,480,100 bp
  • T to C, chromosome 2 at 170,119,144 bp
  • T to A, chromosome 3 at 46,446,689 bp
  • C to T, chromosome 3 at 90,502,115 bp
  • A to G, chromosome 3 at 145,648,268 bp
  • A to T, chromosome 4 at 134,007,973 bp
  • T to C, chromosome 5 at 65,009,046 bp
  • T to C, chromosome 5 at 123,615,154 bp
  • A to T, chromosome 5 at 146,482,382 bp
  • T to C, chromosome 6 at 17,660,765 bp
  • A to G, chromosome 6 at 142,625,731 bp
  • T to C, chromosome 7 at 15,945,962 bp
  • G to C, chromosome 7 at 26,570,640 bp
  • T to C, chromosome 7 at 30,134,430 bp
  • C to A, chromosome 7 at 99,625,742 bp
  • C to T, chromosome 7 at 115,541,621 bp
  • T to C, chromosome 7 at 127,920,579 bp
  • C to A, chromosome 8 at 33,546,336 bp
  • T to C, chromosome 8 at 45,051,209 bp
  • A to G, chromosome 8 at 84,583,731 bp
  • T to C, chromosome 8 at 85,523,256 bp
  • A to G, chromosome 8 at 124,605,844 bp
  • T to C, chromosome 8 at 126,970,130 bp
  • A to G, chromosome 9 at 46,304,005 bp
  • G to A, chromosome 9 at 119,966,666 bp
  • G to A, chromosome 10 at 111,985,793 bp
  • G to T, chromosome 11 at 31,029,021 bp
  • G to A, chromosome 11 at 50,788,667 bp
  • T to A, chromosome 12 at 7,988,781 bp
  • C to T, chromosome 12 at 85,303,515 bp
  • A to G, chromosome 13 at 14,160,271 bp
  • T to A, chromosome 13 at 40,087,849 bp
  • T to A, chromosome 13 at 56,723,804 bp
  • A to G, chromosome 13 at 100,687,114 bp
  • T to C, chromosome 15 at 9,139,479 bp
  • A to T, chromosome 15 at 67,106,673 bp
  • T to C, chromosome 15 at 95,654,723 bp
  • T to C, chromosome 16 at 8,701,981 bp
  • A to T, chromosome 16 at 48,734,941 bp
  • C to T, chromosome 16 at 74,352,784 bp
  • A to T, chromosome 17 at 34,698,910 bp
  • A to T, chromosome 17 at 57,443,990 bp
  • G to A, chromosome 17 at 74,618,424 bp
  • G to A, chromosome 18 at 60,579,471 bp
  • G to T, chromosome 19 at 50,182,775 bp
  • G to A, chromosome X at 10,166,272 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5734 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043348-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.