MMRRC:043353-MU

Synonyms: alpha-latrotoxin receptor (calcium-dependent), neurexin I beta, neurexin I alpha, neurexin I beta, neurexin I beta, neurexin I alpha, neurexin I alpha, 1700062G21Rik, A230068P09Rik, 9330127H16Rik

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 17

MGI: MGI:1096391

NCBI: 18189

Ensembl: ENSMUSG00000024109

VEGA: OTTMUSG00000034567

HGNC: HGNC:8008

Homologene: 21005

CCDS: CCDS57112.1, CCDS57113.1, CCDS84338.1, CCDS84339.1, CCDS84340.1, CCDS84341.1, CCDS84342.1

UCSC: Chr17:90341072-91400587

Ctsll3

Name: cathepsin L-like 3

Synonyms: 2310051M13Rik

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 13

MGI: MGI:1917452

NCBI: 70202

Ensembl: ENSMUSG00000056728

VEGA: 13

HGNC: HGNC:2537

Homologene: 134916

CCDS: CCDS36691.1

UCSC: Chr13:60946064-60950658

Kcnk4

Name: potassium channel, subfamily K, member 4

Synonyms: TRAAKt

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 19

MGI: MGI:1298234

NCBI: 16528

Ensembl: ENSMUSG00000024957

VEGA: 19

HGNC: HGNC:6279

Homologene: 7391

CCDS: CCDS29511.1

UCSC: Chr19:6903030-6912261

Sh2b3

Name: SH2B adaptor protein 3

Synonyms: Lnk

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 5

MGI: MGI:893598

NCBI: 16923

Ensembl: ENSMUSG00000042594

VEGA: OTTMUSG00000029807

HGNC: HGNC:29605

Homologene: 36179

CCDS: CCDS19641.1, CCDS84952.1

UCSC: Chr5:121953544-121975706

Ssrp1

Name: structure specific recognition protein 1

Synonyms: T160, Hmgi-rs3, Hmg1-rs1, Hmgox

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 2

MGI: MGI:107912

NCBI: 20833

Ensembl: ENSMUSG00000027067

VEGA: OTTMUSG00000013453

HGNC: HGNC:11327

Homologene: 110735

CCDS: CCDS38165.1

UCSC: Chr2:84867464-84877458

Spata31f3

Name: spermatogenesis associated 31 subfamily F member 3

Synonyms: BC049635, Fam205c

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 4

MGI: MGI:2679716

NCBI: 277773

Ensembl: ENSMUSG00000050141

VEGA: OTTMUSG00000006597

HGNC: HGNC:42673

Homologene: 77625

CCDS: CCDS18082.1, CCDS89730.1

UCSC: Chr4:42868003-42874246

Vezt

Name: vezatin, adherens junctions transmembrane protein

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 10

MGI: MGI:2143698

NCBI: 215008

Ensembl: ENSMUSG00000036099

VEGA: OTTMUSG00000030972

HGNC: HGNC:18258

Homologene: 9739

CCDS: CCDS36038.1, CCDS78886.1, CCDS78887.1, CCDS83750.1

UCSC: Chr10:93797384-93871661

Slc27a3

Name: solute carrier family 27 (fatty acid transporter), member 3

Synonyms: fatty acid transport protein 3, FATP3, Acsvl3

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 3

MGI: MGI:1347358

NCBI: 26568

Ensembl: ENSMUSG00000027932

VEGA: OTTMUSG00000029600

HGNC: HGNC:10997

Homologene: 11529

CCDS: CCDS17527.1

UCSC: Chr3:90292540-90298693

Trim30d

Name: tripartite motif-containing 30D

Synonyms: TRIM30-3, Trim79

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 7

MGI: MGI:3035181

NCBI: 209387

Ensembl: ENSMUSG00000057596

VEGA: OTTMUSG00000019202

HGNC: HGNC:16276

Homologene: 114426

CCDS: CCDS40069.1, CCDS52347.1

UCSC: Chr7:104119221-104157062

Maml3

Name: mastermind like transcriptional coactivator 3

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 3

MGI: MGI:2389461

NCBI: 433586

Ensembl: ENSMUSG00000061143

VEGA: OTTMUSG00000026673

HGNC: HGNC:16272

Homologene: 41284

CCDS: CCDS17342.2

UCSC: Chr3:51595032-52012740

Zfp128

Name: zinc finger protein 128

Synonyms: mZnf8, 9630016P15Rik

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 7

MGI: MGI:2389445

NCBI: 243833

Ensembl: ENSMUSG00000060397

VEGA: OTTMUSG00000022356

HGNC: HGNC:13154

Homologene: 10889

CCDS: CCDS20815.1

UCSC: Chr7:12615105-12627349

Slc35f1

Name: solute carrier family 35, member F1

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 10

MGI: MGI:2139810

NCBI: 215085

Ensembl: ENSMUSG00000038602

VEGA: OTTMUSG00000023982

HGNC: HGNC:21483

Homologene: 33552

CCDS: CCDS23843.1

UCSC: Chr10:52566597-52987718

Acss2

Name: acyl-CoA synthetase short-chain family member 2

Synonyms: acetyl-CoA synthetase 1, ACAS, AceCS1, Acas1, Acs1, Acas2

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 2

MGI: MGI:1890410

NCBI: 60525

Ensembl: ENSMUSG00000027605

VEGA: OTTMUSG00000016058

HGNC: HGNC:15814

Homologene: 6469

CCDS: CCDS16950.1

UCSC: Chr2:155359963-155404663

Or52e7

Name: olfactory receptor family 52 subfamily E member 7

Synonyms: GA_x6K02T2PBJ9-7664016-7664969, MOR32-1, Olfr676

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 7

MGI: MGI:3030510

NCBI: 259099

Ensembl: ENSMUSG00000073915

VEGA: OTTMUSG00000060556

Homologene: 64955

CCDS: CCDS21637.1

UCSC: Chr7:104680774-104685360

Ankef1

Name: ankyrin repeat and EF-hand domain containing 1

Synonyms: Ankrd5

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 2

MGI: MGI:2441685

NCBI: 319196

Ensembl: ENSMUSG00000074771

VEGA: OTTMUSG00000015561

HGNC: HGNC:15803

Homologene: 11130

CCDS: CCDS38249.1

UCSC: Chr2:136374241-136397774

Ccdc159

Name: coiled-coil domain containing 159

Synonyms: 2510048L02Rik

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 9

MGI: MGI:1914369

NCBI: 67119

Ensembl: ENSMUSG00000006241

VEGA: 9

HGNC: HGNC:26996

Homologene: 12084

CCDS: CCDS40557.1, CCDS52738.1

UCSC: Chr9:21838767-21847168

Rasl10a

Name: RAS-like, family 10, member A

Synonyms: 2210403B10Rik

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 11

MGI: MGI:1922918

NCBI: 75668

Ensembl: ENSMUSG00000034209

VEGA: OTTMUSG00000005072

HGNC: HGNC:16954

Homologene: 4732

CCDS: CCDS24394.1

UCSC: Chr11:5008128-5010385

Prop1

Name: paired like homeodomain factor 1

Synonyms: prophet of Pit1, prophet of Pit-1, Prop-1

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 11

MGI: MGI:109330

NCBI: 19127

Ensembl: ENSMUSG00000044542

VEGA: OTTMUSG00000007884

HGNC: HGNC:9455

Homologene: 4558

CCDS: CCDS24643.1

UCSC: Chr11:50841633-50844584

Pcdhga9

Name: protocadherin gamma subfamily A, 9

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 18

MGI: MGI:1935226

NCBI: 93717

Ensembl: ENSMUSG00000102440

VEGA: OTTMUSG00000050834

HGNC: HGNC:8707

Homologene: 56827

CCDS: CCDS37783.1

UCSC: Chr18:37869989-37974916

Cga

Name: glycoprotein hormones, alpha subunit

Synonyms: GPHalpha, alpha-GSU, Tsha, aGSU, alphaSU, alphaGSU

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 4

MGI: MGI:88390

NCBI: 12640

Ensembl: ENSMUSG00000028298

VEGA: OTTMUSG00000006474

HGNC: HGNC:1885

Homologene: 587

CCDS: CCDS18035.1

UCSC: Chr4:34893779-34907374

Gm20830

Name: predicted gene, 20830

Type: Gene

Species: Mus musculus (mouse)

Chromosome: Y

MGI: MGI:5434186

NCBI: 108168638

Ensembl: ENSMUSG00000096686

VEGA: OTTMUSG00000045702

UCSC: ChrY:6916434-6917118

Gm19402

Name: predicted gene, 19402

Type: Gene

Species: Mus musculus (mouse)

Chromosome: 10

MGI: MGI:5011587

NCBI: 100502831

Ensembl: ENSMUSG00000095970

VEGA: 10

Homologene: 115744

CCDS: CCDS56723.1

UCSC: Chr10:77525791-77526644

Genetic Alterations

ENU-induced transitions at the following base pair locations (GRCm38):

G to T, chromosome 1 at 110,108,845 bp
T to C, chromosome 1 at 144,245,372 bp
G to T, chromosome 1 at 178,122,762 bp
A to G, chromosome 1 at 188,436,962 bp
C to A, chromosome 2 at 69,466,877 bp
T to A, chromosome 2 at 85,041,168 bp
C to A, chromosome 2 at 86,923,205 bp
A to G, chromosome 2 at 136,549,709 bp
A to G, chromosome 2 at 155,574,616 bp
T to A, chromosome 2 at 172,377,833 bp
G to T, chromosome 3 at 52,104,132 bp
G to T, chromosome 3 at 90,387,072 bp
T to A, chromosome 3 at 110,135,420 bp
T to G, chromosome 3 at 121,981,911 bp
T to C, chromosome 4 at 34,904,108 bp
G to A, chromosome 4 at 42,873,087 bp
T to C, chromosome 4 at 58,096,223 bp
T to C, chromosome 4 at 81,421,188 bp
A to C, chromosome 5 at 115,279,882 bp
A to T, chromosome 5 at 121,828,457 bp
A to G, chromosome 5 at 144,750,939 bp
T to C, chromosome 6 at 58,918,799 bp
C to A, chromosome 6 at 70,138,600 bp
A to T, chromosome 6 at 89,356,529 bp
C to T, chromosome 7 at 12,884,727 bp
C to A, chromosome 7 at 19,136,495 bp
T to G, chromosome 7 at 42,476,431 bp
A to T, chromosome 7 at 104,472,328 bp
A to G, chromosome 7 at 105,036,156 bp
T to A, chromosome 7 at 105,771,596 bp
A to G, chromosome 7 at 118,797,011 bp
A to T, chromosome 8 at 15,080,914 bp
A to T, chromosome 8 at 80,615,778 bp
A to T, chromosome 8 at 85,302,956 bp
A to T, chromosome 9 at 21,929,390 bp
C to A, chromosome 9 at 38,180,718 bp
T to A, chromosome 9 at 51,816,727 bp
T to A, chromosome 9 at 62,070,540 bp
T to A, chromosome 9 at 108,534,115 bp
T to G, chromosome 10 at 53,089,450 bp
C to T, chromosome 10 at 77,690,682 bp
A to T, chromosome 10 at 93,997,095 bp
G to A, chromosome 10 at 107,857,001 bp
T to A, chromosome 11 at 5,059,519 bp
T to C, chromosome 11 at 50,951,009 bp
T to G, chromosome 11 at 82,176,886 bp
T to A, chromosome 11 at 115,802,289 bp
G to T, chromosome 13 at 60,801,001 bp
G to T, chromosome 13 at 65,295,680 bp
G to T, chromosome 13 at 112,527,487 bp
A to G, chromosome 13 at 114,884,506 bp
A to T, chromosome 14 at 56,018,615 bp
T to C, chromosome 14 at 93,886,724 bp
G to T, chromosome 15 at 75,779,531 bp
C to A, chromosome 15 at 103,157,616 bp
T to A, chromosome 16 at 35,658,476 bp
G to A, chromosome 17 at 25,244,785 bp
C to A, chromosome 17 at 90,643,224 bp
A to T, chromosome 18 at 37,738,806 bp
A to T, chromosome 19 at 6,928,355 bp
A to G, chromosome Y at 6,916,664 bp

Strain Description [Including phenotype, strain background, strain development and suggested control mice]

Phenotype

G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.

Strain Development

C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.

Suggested Control Mice

Wild-type littermates or C57BL/6J mice

MMRRC Genetic QC

MMRRC Genetic QC Summary

The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.

Strain Origin

Donor

Bruce Beutler, M.D., University of Texas Southwestern Medical Center.

Primary Reference

MUTAGENETIX record for R5743 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information Expand All

Health Status Report

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .

Appearance

Coat Color

Black

Breeding

MMRRC Breeding System

Random intra-strain mating

Breeding Scheme(s)

When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.

Overall Breeding Performance

Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain

Reproductive Statistics

Average litter size

Undetermined

Recommended wean age

3 weeks

Order Request Information Expand All

Availability Level

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Conditions of Distribution [Including applicable technology transfer agreements]

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Fees

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)

MMRRC Item #	Description	Distribution Fee / Unit (US $) Shipping & Handling not included	Units	Notes
043353-MU-RESUS	Litter recovered from cryo-archive	$5,475.00 / Non-Profit	Litter	Recovered litter⁴; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

¹ The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

² An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

³ An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

⁴ The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.

Strain Detail Sheet

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Colony and Husbandry Information Expand All

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