Strain Name:
C57BL/6J-MtgxR5767Btlr
Stock Number:
043367-MU
Citation ID:
RRID:MMRRC_043367-MU
Other Names:
R5767 (G1)
Major Collection:

Gene Information

Cdh1
Name: cadherin 1
Synonyms: uvomorulin, UM, L-CAM, Ecad, E-cadherin, E-cad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12550
HGNC: HGNC:1748
Homologene: 20917
Pmel
Name: premelanosome protein
Synonyms: gp100, Pmel17, D10H12S53E, D12S53Eh, gp87, Si
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 20431
VEGA: 10
Homologene: 5048
Ireb2
Name: iron responsive element binding protein 2
Synonyms: Irp2, D9Ertd85e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 64602
VEGA: 9
HGNC: HGNC:6115
Homologene: 11280
Smarcc1
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
Synonyms: msp3, SRG3, BAF155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 20588
Homologene: 68296
Usp14
Name: ubiquitin specific peptidase 14
Synonyms: 2610005K12Rik, dUB-type TGT, 2610037B11Rik, NMF375, ataxia, nmf375, ax
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 59025
Homologene: 3780
Rcc2
Name: regulator of chromosome condensation 2
Synonyms: 2610510H01Rik, 2610529N02Rik, Td60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 108911
Homologene: 10282
Diaph1
Name: diaphanous related formin 1
Synonyms: Dia1, mDia1, Drf1, p140mDia, D18Wsu154e, Diap1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13367
HGNC: HGNC:2876
Homologene: 129567
Exoc4
Name: exocyst complex component 4
Synonyms: Sec8, Sec8l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 20336
Homologene: 40654
Tbcd
Name: tubulin-specific chaperone d
Synonyms: A030005L14Rik, 2310057L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 108903
Homologene: 4368
Kif15
Name: kinesin family member 15
Synonyms: 3930402I10Rik, Knsl7, 3110023M17Rik, N-10 kinesin, HKLP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 209737
VEGA: 9
Homologene: 23210
Uhrf1bp1l
Name: UHRF1 (ICBP90) binding protein 1-like
Synonyms: 4930506D01Rik, E030041M21Rik, 2010319N22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 75089
VEGA: 10
Homologene: 12590
Ranbp2
Name: RAN binding protein 2
Synonyms: A430087B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 19386
VEGA: 10
Homologene: 87808
Urb1
Name: URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
Synonyms: 4921511H13Rik, 5730405K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 207932
Homologene: 45941
Serpini1
Name: serine (or cysteine) peptidase inhibitor, clade I, member 1
Synonyms: Neuroserpin, Ns, Spi17, PI12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20713
HGNC: HGNC:8943
Homologene: 21045
Arid4a
Name: AT rich interactive domain 4A (RBP1-like)
Synonyms: Rbbp1, A630067N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238247
HGNC: HGNC:9885
Homologene: 11303
Tnfrsf21
Name: tumor necrosis factor receptor superfamily, member 21
Synonyms: TR7, Death receptor 6, DR6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 94185
VEGA: 17
Homologene: 8696
Rasal2
Name: RAS protein activator like 2
Synonyms: A330066M24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226525
HGNC: HGNC:9874
Homologene: 35217
Sgo2a
Name: shugoshin 2A
Synonyms: Sgol2a, 1110007N04Rik, Tripin, Sgol2, 5730576N04Rik, D1Ertd8e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68549
Homologene: 51867
Dsg4
Name: desmoglein 4
Synonyms: lah, CDHF13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 16769
Homologene: 65341
Lgr6
Name: leucine-rich repeat-containing G protein-coupled receptor 6
Synonyms: A530037C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329252
Homologene: 49680
Ms4a14
Name: membrane-spanning 4-domains, subfamily A, member 14
Synonyms: LOC383435
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 383435
Homologene: 138453
Vps13a
Name: vacuolar protein sorting 13A
Synonyms: 4930543C13Rik, D330038K10Rik, 4930516E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 271564
VEGA: 19
HGNC: HGNC:1908
Homologene: 22068
Ptger2
Name: prostaglandin E receptor 2 (subtype EP2)
Synonyms: EP2 receptor, EP2, Ptgerep2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 19217
HGNC: HGNC:9594
Homologene: 739
Itga2
Name: integrin alpha 2
Synonyms: VLA-2 receptor, alpha 2 subunit, DX5, CD49B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 16398
VEGA: 13
HGNC: HGNC:6137
Homologene: 1662
Gls2
Name: glutaminase 2 (liver, mitochondrial)
Synonyms: Lga, A330074B06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216456
Homologene: 40861
Mink1
Name: misshapen-like kinase 1 (zebrafish)
Synonyms: Map4k6, MINK, Misshapen/NIKs-related kinase, Ysk2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 50932
Homologene: 56762
Wdr66
Name: WD repeat domain 66
Synonyms: 4933428F06Rik, 4930415N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 269701
Homologene: 16964
Slc22a30
Name: solute carrier family 22, member 30
Synonyms: C730048C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 319800
Homologene: 77136
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 435626
Homologene: 52359
Kctd16
Name: potassium channel tetramerisation domain containing 16
Synonyms: 4930434H12Rik, 2900055J20Rik, LOC383347
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 73001
VEGA: 18
Homologene: 44779
Cep89
Name: centrosomal protein 89
Synonyms: 2610507L03Rik, Ccdc123
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72140
Homologene: 12444
Tmc3
Name: transmembrane channel-like gene family 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233424
Homologene: 45588
Dennd2d
Name: DENN/MADD domain containing 2D
Synonyms: 2010308M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 72121
Homologene: 11776
C2
Name: complement component 2 (within H-2S)
Synonyms: classical-complement pathway C3/C5 convertase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12263
HGNC: HGNC:1248
Homologene: 45
Armc2
Name: armadillo repeat containing 2
Synonyms: 2610018I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 213402
Homologene: 41848
Actr6
Name: ARP6 actin-related protein 6
Synonyms: 2010200J04Rik, CDA12, Arp6, ArpX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67019
VEGA: 10
Homologene: 6451
Ano3
Name: anoctamin 3
Synonyms: B230324K02Rik, Tmem16c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228432
Homologene: 57147
Fbln5
Name: fibulin 5
Synonyms: EVEC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 23876
VEGA: 12
HGNC: HGNC:3602
Homologene: 38170
Ovch2
Name: ovochymase 2
Synonyms: 9230106D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244199
Homologene: 18255
Olfr175
Name: olfactory receptor 175
Synonyms: MOR184-10P, GA_x54KRFPKG5P-55026345-55025418, GA_x54KRFPKG5P-54993816-54992890, Olfr175-ps1, Olfr174, MOR184-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 259004
Homologene: 17461
Olfr1053
Name: olfactory receptor 1053
Synonyms: Olfr1053-ps1, GA_x6K02T2Q125-47793414-47792471, MOR187-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 257974
Homologene: 74197
Olfr738
Name: olfactory receptor 738
Synonyms: GA_x6K02T2PMLR-6110726-6111661, MOR106-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258662
Homologene: 74220
AI429214
Name: expressed sequence AI429214
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 621080
Homologene: 82747
Wnt2
Name: wingless-type MMTV integration site family, member 2
Synonyms: 2610510E18Rik, Wnt2a, Mirp, m-irp, Int1l1, Wnt-2, Irp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 22413
Homologene: 20719
Zc3h8
Name: zinc finger CCCH type containing 8
Synonyms: Fliz1, E130108N08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 57432
Homologene: 10759
Ifna5
Name: interferon alpha 5
Synonyms: Ifa5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 15968
HGNC: HGNC:5425
Homologene: 68536
Gm27013
Name: predicted gene, 27013
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to T, chromosome 1 at 58,019,660 bp
  • T to C, chromosome 1 at 74,147,663 bp
  • C to T, chromosome 1 at 134,994,010 bp
  • T to C, chromosome 1 at 157,176,162 bp
  • T to A, chromosome 2 at 86,314,398 bp
  • A to T, chromosome 2 at 110,661,271 bp
  • A to T, chromosome 2 at 128,930,892 bp
  • C to T, chromosome 3 at 75,613,081 bp
  • C to T, chromosome 3 at 106,487,815 bp
  • C to A, chromosome 4 at 88,835,799 bp
  • T to A, chromosome 4 at 140,715,919 bp
  • G to A, chromosome 5 at 123,298,521 bp
  • G to T, chromosome 6 at 17,990,028 bp
  • G to A, chromosome 6 at 33,918,432 bp
  • C to T, chromosome 6 at 130,675,958 bp
  • T to A, chromosome 7 at 35,417,645 bp
  • G to A, chromosome 7 at 83,599,982 bp
  • T to C, chromosome 7 at 107,781,978 bp
  • TCCCTGATGAAC to TC, chromosome 8 at 36,994,229 bp
  • C to A, chromosome 8 at 106,668,555 bp
  • A to G, chromosome 9 at 54,900,516 bp
  • G to A, chromosome 9 at 110,132,183 bp
  • A to G, chromosome 9 at 123,013,974 bp
  • A to G, chromosome 10 at 42,011,927 bp
  • T to G, chromosome 10 at 58,476,825 bp
  • A to T, chromosome 10 at 89,726,755 bp
  • A to G, chromosome 10 at 89,787,199 bp
  • A to G, chromosome 10 at 128,205,221 bp
  • T to C, chromosome 10 at 128,714,381 bp
  • A to G, chromosome 11 at 70,606,075 bp
  • A to G, chromosome 11 at 121,592,692 bp
  • A to G, chromosome 12 at 71,060,093 bp
  • A to T, chromosome 12 at 101,765,209 bp
  • C to T, chromosome 13 at 114,839,570 bp
  • G to T, chromosome 14 at 44,989,142 bp
  • T to C, chromosome 14 at 50,413,778 bp
  • T to C, chromosome 16 at 58,823,953 bp
  • T to A, chromosome 16 at 90,776,163 bp
  • T to A, chromosome 17 at 34,876,456 bp
  • A to G, chromosome 17 at 43,037,659 bp
  • A to T, chromosome 18 at 10,009,935 bp
  • T to A, chromosome 18 at 20,462,492 bp
  • T to A, chromosome 18 at 37,853,355 bp
  • A to T, chromosome 18 at 40,258,869 bp
  • G to A, chromosome 19 at 8,344,393 bp
  • G to T, chromosome 19 at 11,302,027 bp
  • T to C, chromosome 19 at 16,664,564 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5767 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043367-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.