Strain Name:
C57BL/6J-MtgxR5770Btlr
Stock Number:
043370-MU
Citation ID:
RRID:MMRRC_043370-MU
Other Names:
R5770 (G1)
Major Collection:

Gene Information

Pcdh9
Name: protocadherin 9
Synonyms: A730003J17Rik, LOC382930, C630029H24Rik, C530050I23Rik, 1500001L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 211712
HGNC: HGNC:8661
Homologene: 10698
Phf21a
Name: PHD finger protein 21A
Synonyms: PFTF1, Bhc80, D030065N23Rik, 80kDa, Braf35/HDAC complex (Bhc)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 192285
Homologene: 9597
1700030C10Rik
Name: RIKEN cDNA 1700030C10 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 69513
Kif11
Name: kinesin family member 11
Synonyms: Eg5, Knsl1, Kifl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16551
VEGA: 19
HGNC: HGNC:6388
Homologene: 3322
Zc3h4
Name: zinc finger CCCH-type containing 4
Synonyms: Bwq1, LOC330474, Kiaa1064-hp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 330474
Homologene: 87150
Sec16a
Name: SEC16 homolog A, endoplasmic reticulum export factor
Synonyms: C230052J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227648
Homologene: 10533
Nudcd3
Name: NudC domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 209586
Homologene: 9097
Ankfy1
Name: ankyrin repeat and FYVE domain containing 1
Synonyms: Ankhzn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11736
Homologene: 9491
Sdha
Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Synonyms: SDHF, SDH2, FP, 2310034D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66945
Homologene: 3073
Zfp292
Name: zinc finger protein 292
Synonyms: 5730450D02Rik, Zn-16, Zfp-15, 9430062L07Rik, Krox-10, Zfp15, Zn-15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 30046
Homologene: 8493
Oprm1
Name: opioid receptor, mu 1
Synonyms: MOP-R, MOR-1, MOP receptor, muOR, mor, Oprm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 18390
HGNC: HGNC:8156
Homologene: 37368
Ints13
Name: integrator complex subunit 13
Synonyms: 4933424B01Rik, Asun, Spata30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 71177
Homologene: 10043
Robo3
Name: roundabout guidance receptor 3
Synonyms: Rig-1, Rig1, Robo3b, Robo3a, Rbig1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19649
Homologene: 32119
Ticam1
Name: toll-like receptor adaptor molecule 1
Synonyms: TICAM-1, Trif
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106759
Homologene: 8605
Gpr68
Name: G protein-coupled receptor 68
Synonyms: OGR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238377
HGNC: HGNC:4519
Homologene: 2603
Macrod2
Name: mono-ADP ribosylhydrolase 2
Synonyms: 1110033L15Rik, 2610107G07Rik, 2900006F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72899
Homologene: 85987
Hk1
Name: hexokinase 1
Synonyms: mHk1-s, Hk1-s, Hk-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 15275
HGNC: HGNC:4922
Homologene: 100530
Pcnx3
Name: pecanex homolog 3
Synonyms: Pcnxl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 104401
Homologene: 17000
Bcl9
Name: B cell CLL/lymphoma 9
Synonyms: 2610202E01Rik, 8030475K17Rik, A330041G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 77578
HGNC: HGNC:1008
Homologene: 3191
Itpkc
Name: inositol 1,4,5-trisphosphate 3-kinase C
Synonyms: 9130023N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233011
Homologene: 11868
Susd2
Name: sushi domain containing 2
Synonyms: 1200011D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 71733
VEGA: 10
Homologene: 10481
Ern2
Name: endoplasmic reticulum (ER) to nucleus signalling 2
Synonyms: Ire1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26918
Homologene: 22687
Abhd8
Name: abhydrolase domain containing 8
Synonyms: 0910001L24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 64296
Homologene: 11188
Tecta
Name: tectorin alpha
Synonyms: [a]-tectorin, Tctna
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 21683
Homologene: 3955
Pdzph1
Name: PDZ and pleckstrin homology domains 1
Synonyms: 2610034M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 69239
Homologene: 130756
Mgam
Name: maltase-glucoamylase
Synonyms: 6030407P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232714
HGNC: HGNC:7043
Homologene: 130099
Myh8
Name: myosin, heavy polypeptide 8, skeletal muscle, perinatal
Synonyms: MyHC-pn, 4832426G23Rik, Myhs-p, Myhsp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 17885
HGNC: HGNC:7578
Homologene: 68256
Olfr980
Name: olfactory receptor 980
Synonyms: MOR223-2, GA_x6K02T2PVTD-33705428-33704496
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 259110
VEGA: 9
Homologene: 81557
Khdrbs3
Name: KH domain containing, RNA binding, signal transduction associated 3
Synonyms: SLM-2, Salp, T-STAR, Etle
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 13992
VEGA: 15
Homologene: 4780
Dll3
Name: delta like canonical Notch ligand 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 13389
HGNC: HGNC:2909
Homologene: 7291
Nat8f5
Name: N-acetyltransferase 8 (GCN5-related) family member 5
Synonyms: Cml5, 1810018F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 69049
Homologene: 87019
Hcrtr2
Name: hypocretin (orexin) receptor 2
Synonyms: mOX2bR, mOXR2, OX2r, mOX2aR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 387285
HGNC: HGNC:4849
Homologene: 1168
Nlrp4b
Name: NLR family, pyrin domain containing 4B
Synonyms: Nalp-gamma, Nalp4b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 210045
Homologene: 65242
Olfr205
Name: olfactory receptor 205
Synonyms: MOR182-11P, GA_x54KRFPKG5P-55543875-55542958
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 257881
Homologene: 79469
Cgnl1
Name: cingulin-like 1
Synonyms: 9930020M10Rik, Jacop, 4933421H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 68178
Homologene: 41901
Shoc1
Name: shortage in chiasmata 1
Synonyms: Gm426, AI481877, Mzip2, LOC242489
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100155
Homologene: 79783
Olfr679
Name: olfactory receptor 679
Synonyms: MOR40-2, GA_x6K02T2PBJ9-7714499-7715446
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259046
Homologene: 81538
Slc22a30
Name: solute carrier family 22, member 30
Synonyms: C730048C13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 319800
Homologene: 77136
Slc16a5
Name: solute carrier family 16 (monocarboxylic acid transporters), member 5
Synonyms: A130015N09Rik, MCT5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217316
Homologene: 20985
Alpk3
Name: alpha-kinase 3
Synonyms: Midori
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 116904
Homologene: 10813
Nmrk1
Name: nicotinamide riboside kinase 1
Synonyms: D630020N23Rik, BC016495
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225994
Homologene: 6787
Usp20
Name: ubiquitin specific peptidase 20
Synonyms: Vdu2, 1700055M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74270
Homologene: 4861
D630003M21Rik
Name: RIKEN cDNA D630003M21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228846
Homologene: 18598
Tgfb1i1
Name: transforming growth factor beta 1 induced transcript 1
Synonyms: ARA55, hic-5, TSC-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 21804
Homologene: 7572
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 76645
Homologene: 124481
Pcdhb19
Name: protocadherin beta 19
Synonyms: Pcdhb11, PcdhbS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93890
HGNC: HGNC:8683
Homologene: 128411
Olfr1384
Name: olfactory receptor 1384
Synonyms: GA_x6K02T2QP88-5922712-5921756, MOR256-23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258464
Homologene: 74259
Olfr314
Name: olfactory receptor 314
Synonyms: GA_x6K02T2NKPP-622179-621244, MOR278-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 257917
Homologene: 133891
Lrrn4
Name: leucine rich repeat neuronal 4
Synonyms: B430119L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 320974
Homologene: 17632
Spata2l
Name: spermatogenesis associated 2-like
Synonyms: 2610039E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 78779
Homologene: 32729
Aoc3
Name: amine oxidase, copper containing 3
Synonyms: semicarbazide-sensitive amine oxidase, SSAO, VAP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11754
HGNC: HGNC:550
Homologene: 2770
Gm6133
Name: predicted gene 6133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 620155
VEGA: 18
Olfr46
Name: olfactory receptor 46
Synonyms: IF5, IB7, GA_x6K02T2PBJ9-42759973-42760905, MOR253-8, ID12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 18345
Homologene: 110491
Gm11595
Name: predicted gene 11595
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 100040276
Homologene: 124486
Kcns3
Name: potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
Synonyms: D12Ertd137e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238076
VEGA: 12
HGNC: HGNC:6302
Homologene: 20518
Desi2
Name: desumoylating isopeptidase 2
Synonyms: Pppde1, 5830417C01Rik, Fam152a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 78825
Homologene: 56741
Cyp2j13
Name: cytochrome P450, family 2, subfamily j, polypeptide 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230459
Homologene: 138297
Olfr1255
Name: olfactory receptor 1255
Synonyms: MOR232-4, GA_x6K02T2Q125-51257221-51258135
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258979
Homologene: 82298
Slc35b3
Name: solute carrier family 35, member B3
Synonyms: 4921526O06Rik, PAPST2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 108652
VEGA: 13
Homologene: 9313
Tpm3-rs7
Name: tropomyosin 3, related sequence 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 621054
VEGA: 14
Nhlrc1
Name: NHL repeat containing 1
Synonyms: Malin, B230309E09Rik, EPM2B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105193
VEGA: 13
Homologene: 18439
Nkx2-3
Name: NK2 homeobox 3
Synonyms: Nkx-2.3, tinman, Nkx2.3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18089
HGNC: HGNC:7836
Homologene: 17061
Prox2
Name: prospero homeobox 2
Synonyms: 1700058C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 73422
Homologene: 18421
Cyp2c44
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 178,256,495 bp
  • T to C, chromosome 2 at 26,414,390 bp
  • A to G, chromosome 2 at 31,017,508 bp
  • T to A, chromosome 2 at 89,816,549 bp
  • C to T, chromosome 2 at 92,351,854 bp
  • C to G, chromosome 2 at 132,872,156 bp
  • T to C, chromosome 2 at 141,232,182 bp
  • T to C, chromosome 2 at 158,195,580 bp
  • T to C, chromosome 3 at 97,215,175 bp
  • A to G, chromosome 4 at 34,806,747 bp
  • T to C, chromosome 4 at 59,092,466 bp
  • A to T, chromosome 4 at 96,077,432 bp
  • A to G, chromosome 6 at 40,669,804 bp
  • T to C, chromosome 6 at 85,817,675 bp
  • T to C, chromosome 6 at 146,555,073 bp
  • T to A, chromosome 7 at 10,715,487 bp
  • T to A, chromosome 7 at 16,429,611 bp
  • T to C, chromosome 7 at 27,212,988 bp
  • T to C, chromosome 7 at 28,299,009 bp
  • A to G, chromosome 7 at 81,078,562 bp
  • A to T, chromosome 7 at 105,090,895 bp
  • C to T, chromosome 7 at 122,179,907 bp
  • A to T, chromosome 7 at 128,248,547 bp
  • A to G, chromosome 7 at 140,610,943 bp
  • A to G, chromosome 8 at 71,457,328 bp
  • C to A, chromosome 8 at 117,055,018 bp
  • A to G, chromosome 8 at 123,235,720 bp
  • T to A, chromosome 9 at 37,419,201 bp
  • C to T, chromosome 9 at 40,006,338 bp
  • T to A, chromosome 9 at 42,345,589 bp
  • C to T, chromosome 9 at 71,645,487 bp
  • T to A, chromosome 9 at 76,259,666 bp
  • G to A, chromosome 10 at 6,789,026 bp
  • T to C, chromosome 10 at 62,286,449 bp
  • T to A, chromosome 10 at 74,185,345 bp
  • C to T, chromosome 10 at 75,638,019 bp
  • T to C, chromosome 11 at 6,113,286 bp
  • A to G, chromosome 11 at 49,514,592 bp
  • G to A, chromosome 11 at 58,786,594 bp
  • G to A, chromosome 11 at 67,297,200 bp
  • C to G, chromosome 11 at 72,760,256 bp
  • G to A, chromosome 11 at 99,772,555 bp
  • T to G, chromosome 11 at 101,331,752 bp
  • A to G, chromosome 11 at 115,472,778 bp
  • A to G, chromosome 12 at 11,092,249 bp
  • T to C, chromosome 12 at 20,815,459 bp
  • A to G, chromosome 12 at 85,087,380 bp
  • A to T, chromosome 12 at 100,878,821 bp
  • A to T, chromosome 13 at 38,937,758 bp
  • A to G, chromosome 13 at 47,014,712 bp
  • A to T, chromosome 13 at 74,323,120 bp
  • G to A, chromosome 14 at 93,886,943 bp
  • A to G, chromosome 14 at 113,315,375 bp
  • T to A, chromosome 15 at 69,049,463 bp
  • A to T, chromosome 16 at 59,329,151 bp
  • TCACACA to TCACA, chromosome 17 at 56,270,629 bp
  • A to T, chromosome 17 at 58,879,151 bp
  • A to G, chromosome 18 at 37,498,037 bp
  • A to G, chromosome 18 at 78,350,249 bp
  • T to C, chromosome 19 at 5,681,579 bp
  • A to T, chromosome 19 at 8,386,527 bp
  • G to T, chromosome 19 at 18,645,074 bp
  • A to G, chromosome 19 at 37,390,865 bp
  • T to A, chromosome 19 at 43,614,533 bp
  • T to A, chromosome 19 at 44,021,579 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5770 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043370-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.