Strain Name:
C57BL/6J-MtgxR5788Btlr
Stock Number:
043382-MU
Citation ID:
RRID:MMRRC_043382-MU
Other Names:
R5788 (G1)
Major Collection:

Gene Information

Espl1
Name: extra spindle pole bodies 1, separase
Synonyms: SSE, ESP1, PRCE, Cerp, separase, PRCE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 105988
VEGA: 15
Homologene: 32151
Ckm
Name: creatine kinase, muscle
Synonyms: Ckmm, M-CK, MCK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12715
HGNC: HGNC:1994
Homologene: 20432
Kcns2
Name: K+ voltage-gated channel, subfamily S, 2
Synonyms: E130006J24Rik, Kv9.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16539
VEGA: 15
HGNC: HGNC:6301
Homologene: 22465
Bahcc1
Name: BAH domain and coiled-coil containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268515
Homologene: 129585
Hcn2
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 2
Synonyms: trls, HAC1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 15166
HGNC: HGNC:4846
Homologene: 31022
Tet1
Name: tet methylcytosine dioxygenase 1
Synonyms: 2510010B09Rik, D10Ertd17e, Cxxc6, BB001228
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 52463
Homologene: 12735
Specc1l
Name: sperm antigen with calponin homology and coiled-coil domains 1-like
Synonyms: 4930470P14Rik, Specc1l, 9530057A13Rik, Cytsa, 4932439K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 74392
VEGA: 10
Homologene: 15610
Hsd17b4
Name: hydroxysteroid (17-beta) dehydrogenase 4
Synonyms: multifunctional protein 2, Mfp-2, 17[b]-HSD, perMFE-2, MFE-2, MFP2, D-bifunctional protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 15488
HGNC: HGNC:5213
Homologene: 358
Bicd1
Name: BICD cargo adaptor 1
Synonyms: B830009D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 12121
HGNC: HGNC:1049
Homologene: 37518
Son
Name: Son DNA binding protein
Synonyms: 2900011L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 20658
Homologene: 10551
Cpsf7
Name: cleavage and polyadenylation specific factor 7
Synonyms: C330017N18Rik, 5730453I16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 269061
VEGA: 19
Homologene: 11731
Thbs1
Name: thrombospondin 1
Synonyms: Thbs-1, TSP-1, TSP1, tbsp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 21825
Homologene: 31142
Rxfp3
Name: relaxin family peptide receptor 3
Synonyms: Rln3r1, Salpr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239336
Homologene: 9568
Uchl1
Name: ubiquitin carboxy-terminal hydrolase L1
Synonyms: PGP 9.5, PGP9.5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22223
Homologene: 37894
Rnd2
Name: Rho family GTPase 2
Synonyms: Rohn, Arhn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11858
Homologene: 21123
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: 9330188B09Rik, D630001M17Rik, 4921513O20Rik, cI-46, LOC381026
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 66725
Homologene: 18982
Naca
Name: nascent polypeptide-associated complex alpha polypeptide
Synonyms: LOC380777, skNAC
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 17938
VEGA: 10
HGNC: HGNC:7629
Homologene: 136025
Zfp266
Name: zinc finger protein 266
Synonyms: 5330440G10Rik, 5730601F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 77519
Homologene: 105676
Fzd2
Name: frizzled class receptor 2
Synonyms: Mfz10, Fz10, Mfz10a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 57265
HGNC: HGNC:4040
Homologene: 20377
Csmd1
Name: CUB and Sushi multiple domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 94109
Homologene: 69536
Zkscan17
Name: zinc finger with KRAB and SCAN domains 17
Synonyms: Zfp496, Nizp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 268417
Homologene: 13108
Amfr
Name: autocrine motility factor receptor
Synonyms: gp78
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 23802
HGNC: HGNC:463
Homologene: 888
Ttn
Name: titin
Synonyms: 2310036G12Rik, mdm, 1100001C23Rik, shru, D830007G01Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, L56, connectin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Olfr1102
Name: olfactory receptor 1102
Synonyms: GA_x6K02T2Q125-48487992-48488966, MOR179-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228228
Homologene: 88426
Tmed4
Name: transmembrane p24 trafficking protein 4
Synonyms: 1110014L17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103694
Homologene: 5308
Hephl1
Name: hephaestin-like 1
Synonyms: zyklopen, thd, Zp, LOC244698, cw
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244698
Homologene: 9112
Naip6
Name: NLR family, apoptosis inhibitory protein 6
Synonyms: Birc1f, Naip-rs4A, Naip-rs4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17952
HGNC: HGNC:7634
Homologene: 113589
Pld4
Name: phospholipase D family, member 4
Synonyms: thss
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 104759
VEGA: 12
Homologene: 16350
Grin2b
Name: glutamate receptor, ionotropic, NMDA2B (epsilon 2)
Synonyms: GluRepsilon2, NMDAR2B, GluN2B, NR2B, Nmdar2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 14812
HGNC: HGNC:4586
Homologene: 646
Tas2r135
Name: taste receptor, type 2, member 135
Synonyms: mt2r38, Tas2r35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387512
Homologene: 52230
Ankrd60
Name: ankyrin repeat domain 60
Synonyms: 1700030G11Rik, 1700019A24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 70065
Homologene: 43792
Gm4787
Name: predicted gene 4787
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 214321
Homologene: 86950
Flg2
Name: filaggrin family member 2
Synonyms: EG229574
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229574
Homologene: 134146
Pcid2
Name: PCI domain containing 2
Synonyms: A730042J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234069
Homologene: 10168
Nwd2
Name: NACHT and WD repeat domain containing 2
Synonyms: 3110047P20Rik, B830017A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319807
Homologene: 14974
Wsb2
Name: WD repeat and SOCS box-containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 59043
Homologene: 32417
Hinfp
Name: histone H4 transcription factor
Synonyms: Mizf, DKFZp434F162
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102423
VEGA: 9
Homologene: 9174
Ano5
Name: anoctamin 5
Synonyms: Tmem16e, Gdd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233246
Homologene: 100071
Acot11
Name: acyl-CoA thioesterase 11
Synonyms: Thea, 1110020M10Rik, Them1, BFIT1, 2010309H15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329910
Homologene: 11977
Ipo4
Name: importin 4
Synonyms: 8430408O15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 75751
Homologene: 5835
Evi5l
Name: ecotropic viral integration site 5 like
Synonyms: B130050I23Rik, 3110007G05Rik, 1700084G18Rik, 2310039H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 213027
Homologene: 134635
Atp8a2
Name: ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
Synonyms: wl, agil, Ib
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 50769
Homologene: 4443
Ccdc66
Name: coiled-coil domain containing 66
Synonyms: E230015L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 320234
VEGA: 14
Homologene: 35309
Pogk
Name: pogo transposable element with KRAB domain
Synonyms: BASS2, 9130401E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71592
Homologene: 32346
Acadsb
Name: acyl-Coenzyme A dehydrogenase, short/branched chain
Synonyms: 1300003O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66885
HGNC: HGNC:91
Homologene: 1216
Rhbg
Name: Rhesus blood group-associated B glycoprotein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 58176
Homologene: 9469
Dkk4
Name: dickkopf WNT signaling pathway inhibitor 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 234130
HGNC: HGNC:2894
Homologene: 8680
Olfr503
Name: olfactory receptor 503
Synonyms: MOR34-9, MOR34-12, MOR34-9, GA_x6K02T2PBJ9-10874315-10875286, Olfr1548, MOR34-8P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259143
Homologene: 121509
Kif1c
Name: kinesin family member 1C
Synonyms: N-3 kinsin, D11Bwg1349e, B430105J22Rik, Orch3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 16562
HGNC: HGNC:6317
Homologene: 4821
Gm10428
Name: predicted gene 10428
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Fancg
Name: Fanconi anemia, complementation group G
Synonyms: Xrcc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 60534
HGNC: HGNC:3588
Homologene: 3402
Olfr790
Name: olfactory receptor 790
Synonyms: GA_x6K02T2PULF-11179777-11180721, MOR112-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258935
Homologene: 74101
Ndufs2
Name: NADH:ubiquinone oxidoreductase core subunit S2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226646
HGNC: HGNC:7708
Homologene: 56659
Teddm2
Name: transmembrane epididymal family member 2
Synonyms: 5830403L16Rik, e9-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 240817
Homologene: 65346
Gm15121
Name: predicted gene 15121
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Gm1988
Name: predicted gene 1988
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100038967
Homologene: 80005
Gm7133
Name: predicted gene 7133
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 634331
Homologene: 86643
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 97,243,476 bp
  • A to T, chromosome 1 at 153,851,064 bp
  • A to T, chromosome 1 at 166,409,011 bp
  • A to G, chromosome 1 at 171,239,385 bp
  • A to T, chromosome 2 at 76,919,231 bp
  • A to G, chromosome 2 at 87,002,301 bp
  • T to A, chromosome 2 at 118,122,508 bp
  • TGGCCACGCGG to TGG, chromosome 2 at 173,578,089 bp
  • C to T, chromosome 3 at 88,245,567 bp
  • A to T, chromosome 3 at 93,200,989 bp
  • A to T, chromosome 4 at 43,007,130 bp
  • C to T, chromosome 4 at 106,760,130 bp
  • T to C, chromosome 5 at 63,807,771 bp
  • T to A, chromosome 5 at 66,676,411 bp
  • A to G, chromosome 5 at 117,377,418 bp
  • T to A, chromosome 6 at 42,405,597 bp
  • T to C, chromosome 6 at 135,740,964 bp
  • T to C, chromosome 6 at 149,484,000 bp
  • A to G, chromosome 7 at 19,419,447 bp
  • T to A, chromosome 7 at 39,172,203 bp
  • G to A, chromosome 7 at 51,566,318 bp
  • C to T, chromosome 7 at 103,460,879 bp
  • T to C, chromosome 7 at 108,545,344 bp
  • A to G, chromosome 7 at 131,443,599 bp
  • A to T, chromosome 8 at 4,206,800 bp
  • C to T, chromosome 8 at 13,100,320 bp
  • T to C, chromosome 8 at 16,201,966 bp
  • T to C, chromosome 8 at 22,625,331 bp
  • T to A, chromosome 8 at 94,000,314 bp
  • A to G, chromosome 9 at 15,084,283 bp
  • A to G, chromosome 9 at 20,506,036 bp
  • C to T, chromosome 9 at 44,297,808 bp
  • T to C, chromosome 10 at 62,839,958 bp
  • G to T, chromosome 10 at 75,276,921 bp
  • T to C, chromosome 10 at 79,717,111 bp
  • G to A, chromosome 10 at 128,040,142 bp
  • A to T, chromosome 10 at 129,500,894 bp
  • A to G, chromosome 10 at 129,500,910 bp
  • A to G, chromosome 11 at 6,271,743 bp
  • A to G, chromosome 11 at 59,487,260 bp
  • T to G, chromosome 11 at 62,753,281 bp
  • T to A, chromosome 11 at 70,708,828 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • A to T, chromosome 11 at 102,605,467 bp
  • A to G, chromosome 11 at 120,286,352 bp
  • G to C, chromosome 12 at 81,377,830 bp
  • A to C, chromosome 12 at 112,764,117 bp
  • G to T, chromosome 13 at 100,300,216 bp
  • C to T, chromosome 14 at 27,498,491 bp
  • C to T, chromosome 14 at 55,628,820 bp
  • T to A, chromosome 14 at 60,020,793 bp
  • A to G, chromosome 15 at 11,036,164 bp
  • A to C, chromosome 15 at 34,838,854 bp
  • T to G, chromosome 15 at 91,764,648 bp
  • T to A, chromosome 15 at 102,324,030 bp
  • A to G, chromosome 16 at 91,660,052 bp
  • G to A, chromosome 18 at 50,173,709 bp
  • T to G, chromosome 19 at 10,540,718 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5788 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043382-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.