Strain Name:
C57BL/6J-MtgxR5789Btlr
Stock Number:
043383-MU
Citation ID:
RRID:MMRRC_043383-MU
Other Names:
R5789 (G1)
Major Collection:

Gene Information

Cops3
Name: COP9 signalosome subunit 3
Synonyms: Csn3, COP9 complex S3, Sgn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 26572
VEGA: 11
HGNC: HGNC:2239
Homologene: 2710
Socs3
Name: suppressor of cytokine signaling 3
Synonyms: E2a-Pbx1 target gene in fibroblasts 10, SSI-3, Cish3, STAT-induced STAT inhibitor 3, CIS3, cytokine-inducible SH2 protein 3, EF-10, SOCS-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12702
VEGA: 11
Homologene: 2941
Dclre1c
Name: DNA cross-link repair 1C
Synonyms: 9930121L06Rik, Artemis, Art
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 227525
VEGA: 2
Homologene: 32547
Ptpn12
Name: protein tyrosine phosphatase, non-receptor type 12
Synonyms: PTP-P19, PTP-PEST, P19-PTP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19248
VEGA: 5
HGNC: HGNC:9645
Homologene: 37691
Wasf1
Name: WAS protein family, member 1
Synonyms: WAVE-1, WAVE, Scar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 83767
VEGA: 10
Homologene: 2920
Xpnpep3
Name: X-prolyl aminopeptidase 3, mitochondrial
Synonyms: E430012M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 321003
VEGA: 15
Carmil1
Name: capping protein regulator and myosin 1 linker 1
Synonyms: Carmil, Lrrc16, Lrrc16a, 1110037D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 68732
VEGA: 13
Homologene: 9757
Tcf12
Name: transcription factor 12
Synonyms: HTF-4, ALF1, HEB, HTF4, ME1, HEBAlt, bHLHb20, REB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21406
VEGA: 9
Homologene: 40774
Kmt2a
Name: lysine (K)-specific methyltransferase 2A
Synonyms: trithorax Drosophila, HTRX1, Cxxc7, Mll1, All1, Mll, ALL-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 214162
VEGA: 9
HGNC: HGNC:7132
Homologene: 4338
Yars
Name: tyrosyl-tRNA synthetase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 107271
VEGA: 4
Homologene: 2730
Slc12a2
Name: solute carrier family 12, member 2
Synonyms: sy-ns, Nkcc1, mBSC2, sodium/potassium/chloride cotransporters
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 20496
VEGA: 18
Homologene: 20283
Mtrex
Name: Mtr4 exosome RNA helicase
Synonyms: 2610528A15Rik, Skiv2l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 72198
VEGA: 13
Homologene: 6257
Zfp90
Name: zinc finger protein 90
Synonyms: Zfp64, KRAB17, 6430515L01Rik, NK10, Zfp83, Nk10 expressed protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 22751
VEGA: 8
Homologene: 86800
Tmem135
Name: transmembrane protein 135
Synonyms: 2810439K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72759
VEGA: 7
Homologene: 11295
Supt6
Name: SPT6, histone chaperone and transcription elongation factor
Synonyms: Supt6h, 5131400N11Rik, SPT6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20926
VEGA: 11
Homologene: 40661
Cdan1
Name: congenital dyserythropoietic anemia, type I (human)
Synonyms: 1500015A01Rik, CDA1, CDA-I, codanin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 68968
VEGA: 2
HGNC: HGNC:1713
Homologene: 16324
Fam180a
Name: family with sequence similarity 180, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 208164
VEGA: 6
Homologene: 18283
Gfral
Name: GDNF family receptor alpha like
Synonyms: GRAL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 404194
Homologene: 45748
Tmem170
Name: transmembrane protein 170
Synonyms: 9030409E16Rik, D8Bwg1414e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 66817
VEGA: 8
Homologene: 12040
Coq7
Name: demethyl-Q 7
Synonyms: clk-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 12850
VEGA: 7
HGNC: HGNC:2244
Homologene: 6953
Eif2b3
Name: eukaryotic translation initiation factor 2B, subunit 3
Synonyms: 1190002P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 108067
VEGA: 4
HGNC: HGNC:3259
Homologene: 7005
Inpp4a
Name: inositol polyphosphate-4-phosphatase, type I
Synonyms: 107kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 269180
VEGA: 1
HGNC: HGNC:6074
Homologene: 2871
Zscan22
Name: zinc finger and SCAN domain containing 22
Synonyms: D530006B18Rik, Hkr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232878
VEGA: 7
HGNC: HGNC:4929
Homologene: 68122
Dhx37
Name: DEAH (Asp-Glu-Ala-His) box polypeptide 37
Synonyms: LOC381671, LOC208144
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 208144
VEGA: 5
Homologene: 6641
Enpp1
Name: ectonucleotide pyrophosphatase/phosphodiesterase 1
Synonyms: Pca-1, CD203c, E-NPP1, PC-1, NPP1, Ly-41, Pca, Npps, 4833416E15Rik, Pdnp1, twy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 18605
VEGA: 10
HGNC: HGNC:3356
Homologene: 38151
Dnajc13
Name: DnaJ heat shock protein family (Hsp40) member C13
Synonyms: D030002L11Rik, LOC382100, Rme8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235567
VEGA: 9
Homologene: 13574
Cp
Name: ceruloplasmin
Synonyms: D3Ertd555e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12870
VEGA: 3
HGNC: HGNC:2295
Homologene: 75
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 77505
VEGA: 7
Homologene: 131117
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381917
VEGA: 7
HGNC: HGNC:2949
Homologene: 19674
Abcb11
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 11
Synonyms: sister of P-glycoprotein, Bsep, PGY4, ABC16, PFIC2, Lith1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 27413
VEGA: 2
HGNC: HGNC:42
Homologene: 74509
Nckap5
Name: NCK-associated protein 5
Synonyms: LOC380609, E030049G20Rik, D130011D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 210356
VEGA: 1
Homologene: 35542
Uroc1
Name: urocanase domain containing 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243537
VEGA: 6
Homologene: 76629
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: 2310047C17Rik, 1110004P15Rik, DY6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Gm7455, Col6a5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 665033
Homologene: 122792
Ciao3
Name: cytosolic iron-sulfur assembly component 3
Synonyms: Narfl, 9030612I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 67563
VEGA: 17
Homologene: 6750
D630003M21Rik
Name: RIKEN cDNA D630003M21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228846
Homologene: 18598
Col6a2
Name: collagen, type VI, alpha 2
Synonyms: Col6a-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 12834
VEGA: 10
HGNC: HGNC:2212
Homologene: 1392
Aqp1
Name: aquaporin 1
Synonyms: CHIP28
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 11826
VEGA: 6
HGNC: HGNC:633
Homologene: 68051
Sh2d2a
Name: SH2 domain containing 2A
Synonyms: Lck-associated adapter protein, Rlk/Itk-binding protein, TSAd, RIBP, Lad
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 27371
VEGA: 3
Homologene: 2958
C9orf72
Name: C9orf72, member of C9orf72-SMCR8 complex
Synonyms: 3110043O21Rik, Dennd9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 73205
VEGA: 4
Homologene: 10137
Doc2b
Name: double C2, beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 13447
VEGA: 11
HGNC: HGNC:2986
Homologene: 20796
Nudcd1
Name: NudC domain containing 1
Synonyms: 4921532K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 67429
VEGA: 15
Homologene: 12128
Samsn1
Name: SAM domain, SH3 domain and nuclear localization signals, 1
Synonyms: 4930571B16Rik, Hacs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 67742
VEGA: 16
Homologene: 11148
Gabra1
Name: gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
Synonyms: GABAAR alpha1, Gabra-1, GABAA alpha 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14394
VEGA: 11
HGNC: HGNC:4075
Homologene: 629
Them5
Name: thioesterase superfamily member 5
Synonyms: 1110038F21Rik, 1110007B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66198
VEGA: 3
Homologene: 11931
Ifi213
Name: interferon activated gene 213
Synonyms: Pyr-A, E030037K03Rik, Pydc4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 623121
HGNC: HGNC:5395
Homologene: 115929
Plekhb1
Name: pleckstrin homology domain containing, family B (evectins) member 1
Synonyms: Phret1, evt-1, PHR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 27276
VEGA: 7
Homologene: 8449
Zdhhc16
Name: zinc finger, DHHC domain containing 16
Synonyms: APH2, 1500015N03Rik, Ablphilin 2, Abl-philin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 74168
VEGA: 19
Homologene: 11377
Aloxe3
Name: arachidonate lipoxygenase 3
Synonyms: e-LOX-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 23801
VEGA: 11
Homologene: 8013
Prrt1
Name: proline-rich transmembrane protein 1
Synonyms: G5b, SynDIG4, NG5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 260297
VEGA: 17
Homologene: 134500
Trbv20
Name: T cell receptor beta, variable 20
Synonyms: Gm16911, Tcrb-V15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 100124685
VEGA: 6
Gm16551
Name: predicted gene 16551
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 100503019
Pcdhgc5
Name: protocadherin gamma subfamily C, 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93708
VEGA: 18
HGNC: HGNC:8718
Homologene: 110933
Mrgprb13
Name: MAS-related GPR, member B13
Synonyms: MrgB13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 620137
VEGA: 7
Homologene: 83620
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 37,372,329 bp
  • A to G, chromosome 1 at 126,027,702 bp
  • C to A, chromosome 1 at 173,568,794 bp
  • A to T, chromosome 2 at 3,437,956 bp
  • A to G, chromosome 2 at 69,245,764 bp
  • A to G, chromosome 2 at 120,729,535 bp
  • C to T, chromosome 2 at 158,216,814 bp
  • T to A, chromosome 3 at 19,957,290 bp
  • T to A, chromosome 3 at 87,849,513 bp
  • A to G, chromosome 3 at 94,346,601 bp
  • T to A, chromosome 4 at 35,226,112 bp
  • T to A, chromosome 4 at 117,028,495 bp
  • C to T, chromosome 4 at 129,196,897 bp
  • G to A, chromosome 5 at 20,989,015 bp
  • A to C, chromosome 5 at 125,421,039 bp
  • C to A, chromosome 6 at 35,313,526 bp
  • A to G, chromosome 6 at 41,188,791 bp
  • A to G, chromosome 6 at 55,336,761 bp
  • A to G, chromosome 6 at 90,344,197 bp
  • T to G, chromosome 7 at 12,903,926 bp
  • A to T, chromosome 7 at 48,312,198 bp
  • A to G, chromosome 7 at 89,196,122 bp
  • A to T, chromosome 7 at 100,645,586 bp
  • A to G, chromosome 7 at 105,705,010 bp
  • G to T, chromosome 7 at 118,529,706 bp
  • G to T, chromosome 7 at 119,943,599 bp
  • T to C, chromosome 8 at 106,423,973 bp
  • A to G, chromosome 8 at 111,866,400 bp
  • T to C, chromosome 9 at 44,819,904 bp
  • T to C, chromosome 9 at 71,885,236 bp
  • T to A, chromosome 9 at 74,849,253 bp
  • C to T, chromosome 9 at 76,197,046 bp
  • T to C, chromosome 9 at 104,214,188 bp
  • T to C, chromosome 9 at 105,864,608 bp
  • A to T, chromosome 10 at 24,647,239 bp
  • G to A, chromosome 10 at 40,926,574 bp
  • T to A, chromosome 10 at 76,604,389 bp
  • A to T, chromosome 11 at 42,182,915 bp
  • T to C, chromosome 11 at 59,830,280 bp
  • T to C, chromosome 11 at 69,126,439 bp
  • T to A, chromosome 11 at 75,786,115 bp
  • A to G, chromosome 11 at 78,233,586 bp
  • T to A, chromosome 11 at 117,967,782 bp
  • A to G, chromosome 13 at 24,121,848 bp
  • A to T, chromosome 13 at 112,891,285 bp
  • G to A, chromosome 15 at 44,388,483 bp
  • T to A, chromosome 15 at 81,415,864 bp
  • T to C, chromosome 16 at 75,876,448 bp
  • T to C, chromosome 17 at 25,781,203 bp
  • T to C, chromosome 17 at 34,631,957 bp
  • C to A, chromosome 18 at 37,821,506 bp
  • T to A, chromosome 18 at 57,912,019 bp
  • A to T, chromosome 19 at 9,002,321 bp
  • T to A, chromosome 19 at 41,938,133 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5789 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043383-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.