Strain Name:
C57BL/6J-MtgxR5795Btlr
Stock Number:
043386-MU
Citation ID:
RRID:MMRRC_043386-MU
Other Names:
R5795 (G1)
Major Collection:

Gene Information

Chrna3
Name: cholinergic receptor, nicotinic, alpha polypeptide 3
Synonyms: alpha 3, Acra-3, A730007P14Rik, (a)3, neuronal nicotinic acetylcholine receptor, alpha 3 subunit, Acra3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 110834
VEGA: 9
HGNC: HGNC:1957
Homologene: 591
Adipor1
Name: adiponectin receptor 1
Synonyms: 2810031L11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72674
Homologene: 69199
Tanc1
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Synonyms: 1200003E16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66860
Homologene: 18946
Slc31a2
Name: solute carrier family 31, member 2
Synonyms: Ctr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 20530
Homologene: 37536
Ercc6
Name: excision repair cross-complementing rodent repair deficiency, complementation group 6
Synonyms: CSB, C130058G22Rik, CS group B correcting gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 319955
VEGA: 14
HGNC: HGNC:3438
Homologene: 133552
Hmmr
Name: hyaluronan mediated motility receptor (RHAMM)
Synonyms: CD168, Rhamm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 15366
HGNC: HGNC:5012
Homologene: 8271
Tango6
Name: transport and golgi organization 6
Synonyms: Tango6, Tmco7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 272538
Homologene: 52121
Polr3b
Name: polymerase (RNA) III (DNA directed) polypeptide B
Synonyms: 2700078H01Rik, A330032P03Rik, RPC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70428
VEGA: 10
Homologene: 6981
Chmp5
Name: charged multivesicular body protein 5
Synonyms: 2210412K09Rik, chromatin modifying protein 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 76959
Homologene: 5757
Brat1
Name: BRCA1-associated ATM activator 1
Synonyms: Baat1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231841
Homologene: 16776
Irf7
Name: interferon regulatory factor 7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 54123
HGNC: HGNC:6122
Homologene: 128624
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Appl1
Name: adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Synonyms: 7330406P05Rik, 2900057D21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 72993
Homologene: 32143
Paf1
Name: Paf1, RNA polymerase II complex component
Synonyms: 5730511K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 54624
Homologene: 5441
Tbc1d32
Name: TBC1 domain family, member 32
Synonyms: Bromi, C6orf170, b2b2284Clo, D630037F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 544696
VEGA: 10
Homologene: 51889
F5
Name: coagulation factor V
Synonyms: Cf5, Cf-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Ush2a
Name: usherin
Synonyms: MUSH2A, A930011D15Rik, Ushrn, Ush2a, LOC269160, LOC381317, A930037M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22283
Homologene: 66151
Hephl1
Name: hephaestin-like 1
Synonyms: Zp, thd, zyklopen, cw, LOC244698
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244698
Homologene: 9112
Pdzph1
Name: PDZ and pleckstrin homology domains 1
Synonyms: 2610034M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 69239
Homologene: 130756
Ogfod2
Name: 2-oxoglutarate and iron-dependent oxygenase domain containing 2
Synonyms: 1300006G11Rik, 5730405M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66627
Homologene: 32588
Mink1
Name: misshapen-like kinase 1 (zebrafish)
Synonyms: MINK, Misshapen/NIKs-related kinase, Ysk2, Map4k6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 50932
Homologene: 56762
Lrp4
Name: low density lipoprotein receptor-related protein 4
Synonyms: mdig, Megf7, 6430526J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228357
HGNC: HGNC:6696
Homologene: 17964
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC9, MUC5, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Cblif
Name: cobalamin binding intrinsic factor
Synonyms: Gif
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 14603
HGNC: HGNC:4268
Homologene: 3773
Ahnak
Name: AHNAK nucleoprotein (desmoyokin)
Synonyms: 2310047C17Rik, DY6, 1110004P15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Acpp
Name: acid phosphatase, prostate
Synonyms: PAP, A030005E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56318
HGNC: HGNC:125
Homologene: 55552
Sfi1
Name: Sfi1 homolog, spindle assembly associated (yeast)
Synonyms: 2310047I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 78887
Homologene: 12707
Slc28a2b
Name: solute carrier family 28 member 2b
Synonyms: Gm14085
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381417
Tas2r125
Name: taste receptor, type 2, member 125
Synonyms: mt2r59, Tas2r25, T2R26, mGR25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 387352
Homologene: 87294
Vmn2r104
Name: vomeronasal 2, receptor 104
Synonyms: V2r7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22313
Homologene: 129751
Pcdh8
Name: protocadherin 8
Synonyms: 1700080P15Rik, Papc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18530
HGNC: HGNC:8660
Homologene: 1943
Vmn2r105
Name: vomeronasal 2, receptor 105
Synonyms: EG627743
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 627743
Homologene: 129680
Ccs
Name: copper chaperone for superoxide dismutase
Synonyms: CCS, Ccsd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 12460
VEGA: 19
HGNC: HGNC:1613
Homologene: 3762
Ankrd24
Name: ankyrin repeat domain 24
Synonyms: 5730519E19Rik, 4631433D01Rik, D10Bur2e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70615
Homologene: 49885
C5ar1
Name: complement component 5a receptor 1
Synonyms: C5r1, D7Msu1, C5aR, Cd88
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12273
HGNC: HGNC:1338
Homologene: 20413
Olfr1448
Name: olfactory receptor 1448
Synonyms: GA_x6K02T2RE5P-3249780-3248836, MOR202-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258696
Homologene: 64904
Crocc
Name: ciliary rootlet coiled-coil, rootletin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230872
Homologene: 16811
Hsd11b1
Name: hydroxysteroid 11-beta dehydrogenase 1
Synonyms: 11beta-hydroxysteroid dehydrogenase type 1, 11beta-HSD-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 15483
HGNC: HGNC:5208
Homologene: 68471
Dbndd1
Name: dysbindin (dystrobrevin binding protein 1) domain containing 1
Synonyms: 2810427I04Rik, D8Ertd590e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72185
Homologene: 11433
Bmp8b
Name: bone morphogenetic protein 8b
Synonyms: Op3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12164
HGNC: HGNC:1075
Homologene: 130625
Ilvbl
Name: ilvB (bacterial acetolactate synthase)-like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216136
VEGA: 10
HGNC: HGNC:6041
Homologene: 68532
Zfp316
Name: zinc finger protein 316
Synonyms: Emzf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 54201
Homologene: 69231
Minpp1
Name: multiple inositol polyphosphate histidine phosphatase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 17330
VEGA: 19
HGNC: HGNC:7102
Homologene: 37980
Spire1
Name: spire type actin nucleation factor 1
Synonyms: Spir-1, 6030430B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68166
VEGA: 18
Homologene: 35507
Olfr91
Name: olfactory receptor 91
Synonyms: GA_x6K02T2PSCP-1533927-1532989, MOR256-20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258470
HGNC: HGNC:8252
Homologene: 72346
Zfp456
Name: zinc finger protein 456
Synonyms: Rslcan-13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 408065
Homologene: 110878
Traf5
Name: TNF receptor-associated factor 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22033
Homologene: 27079
Csf3
Name: colony stimulating factor 3 (granulocyte)
Synonyms: MGI-IG, G-CSF, Csfg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 12985
HGNC: HGNC:2438
Homologene: 7677
Mycl
Name: v-myc avian myelocytomatosis viral oncogene lung carcinoma derived
Synonyms: Lmyc-1, Lmyc1, L-myc, Mycl1, bHLHe38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16918
HGNC: HGNC:7555
Homologene: 3921
Oaf
Name: out at first homolog
Synonyms: D130038B21Rik, D9Ucla1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 102644
VEGA: 9
Homologene: 14334
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 134,424,903 bp
  • C to T, chromosome 1 at 164,152,009 bp
  • A to T, chromosome 1 at 188,443,397 bp
  • T to C, chromosome 1 at 191,999,846 bp
  • A to G, chromosome 1 at 193,240,632 bp
  • A to G, chromosome 2 at 59,807,582 bp
  • A to G, chromosome 2 at 91,474,471 bp
  • T to C, chromosome 2 at 122,517,994 bp
  • T to G, chromosome 4 at 40,950,562 bp
  • T to C, chromosome 4 at 62,297,052 bp
  • G to A, chromosome 4 at 122,996,622 bp
  • C to A, chromosome 4 at 123,121,968 bp
  • TCTGAGCTGCTGAGCTGC to TCTGAGCTGC, chromosome 4 at 141,041,807 bp
  • G to A, chromosome 5 at 124,114,761 bp
  • G to T, chromosome 5 at 140,713,072 bp
  • A to T, chromosome 5 at 143,262,839 bp
  • G to A, chromosome 6 at 132,909,658 bp
  • T to C, chromosome 7 at 16,248,394 bp
  • T to G, chromosome 7 at 28,396,618 bp
  • G to A, chromosome 7 at 141,265,116 bp
  • G to A, chromosome 7 at 141,871,741 bp
  • T to A, chromosome 8 at 106,718,077 bp
  • A to G, chromosome 8 at 123,509,880 bp
  • C to T, chromosome 9 at 15,069,760 bp
  • T to A, chromosome 9 at 43,223,944 bp
  • T to A, chromosome 9 at 55,015,268 bp
  • A to G, chromosome 9 at 104,309,489 bp
  • A to T, chromosome 10 at 56,215,062 bp
  • T to C, chromosome 10 at 78,577,144 bp
  • C to A, chromosome 10 at 81,645,103 bp
  • A to T, chromosome 10 at 84,628,252 bp
  • T to C, chromosome 10 at 84,677,011 bp
  • A to ATCTTCCCAAAGCCAGTGC, chromosome 11 at 3,153,384 bp
  • T to A, chromosome 11 at 40,721,906 bp
  • T to C, chromosome 11 at 70,607,790 bp
  • G to T, chromosome 11 at 98,702,027 bp
  • A to T, chromosome 13 at 67,366,920 bp
  • G to T, chromosome 14 at 26,942,816 bp
  • A to G, chromosome 14 at 32,526,352 bp
  • T to C, chromosome 14 at 79,770,980 bp
  • G to T, chromosome 17 at 20,030,110 bp
  • A to G, chromosome 17 at 20,030,282 bp
  • A to T, chromosome 17 at 20,228,736 bp
  • A to G, chromosome 17 at 37,093,769 bp
  • A to G, chromosome 17 at 58,885,867 bp
  • A to G, chromosome 17 at 67,796,727 bp
  • A to T, chromosome 18 at 67,495,195 bp
  • A to G, chromosome 19 at 4,833,339 bp
  • A to T, chromosome 19 at 9,012,382 bp
  • A to G, chromosome 19 at 11,760,376 bp
  • A to G, chromosome 19 at 12,919,824 bp
  • G to A, chromosome 19 at 32,514,157 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5795 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043386-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.