Strain Name:
C57BL/6J-MtgxR5814Btlr
Stock Number:
043396-MU
Citation ID:
RRID:MMRRC_043396-MU
Other Names:
R5814 (G1)
Major Collection:

Gene Information

Sema3e
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Synonyms: Semah
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 20349
Homologene: 8247
Vps33a
Name: VPS33A CORVET/HOPS core subunit
Synonyms: bf, 3830421M04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 77573
Homologene: 11294
Hgf
Name: hepatocyte growth factor
Synonyms: NK1, C230052L06Rik, NK2, HGF/SF, scatter factor, SF/HGF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 15234
HGNC: HGNC:4893
Homologene: 503
Mmp10
Name: matrix metallopeptidase 10
Synonyms: stromelysin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17384
VEGA: 9
HGNC: HGNC:7156
Homologene: 20546
Ep400
Name: E1A binding protein p400
Synonyms: mDomino, p400, 1700020J09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75560
Homologene: 38779
Pcf11
Name: PCF11 cleavage and polyadenylation factor subunit
Synonyms: 5730417B17Rik, 2500001H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74737
Homologene: 32282
Srsf11
Name: serine and arginine-rich splicing factor 11
Synonyms: Sfrs11, 2610019N13Rik, 0610009J05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 69207
Homologene: 36164
Dnmt3b
Name: DNA methyltransferase 3B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13436
HGNC: HGNC:2979
Homologene: 56000
Rpsa
Name: ribosomal protein SA
Synonyms: Lamr1, P40-8, Lamrl1, Lamr, 67lr, P40-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 16785
VEGA: 9
HGNC: HGNC:6502
Homologene: 68249
Setd2
Name: SET domain containing 2
Synonyms: KMT3A, 4921524K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235626
Homologene: 56493
Lin9
Name: lin-9 homolog (C. elegans)
Synonyms: 2700022J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 72568
Homologene: 35252
Utp4
Name: UTP4 small subunit processome component
Synonyms: TEG-292, Cirh1a, Tex292
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 21771
HGNC: HGNC:1983
Homologene: 40775
Arrdc3
Name: arrestin domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105171
Homologene: 69318
Crot
Name: carnitine O-octanoyltransferase
Synonyms: 1200003H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74114
HGNC: HGNC:2366
Homologene: 10899
Sh3d19
Name: SH3 domain protein D19
Synonyms: Kryn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 27059
Homologene: 19064
Cit
Name: citron
Synonyms: C030025P15Rik, Cit-k, citron kinase, CRIK-SK, citron-N
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 12704
HGNC: HGNC:1985
Homologene: 21404
Pcbp2
Name: poly(rC) binding protein 2
Synonyms: alphaCP-2, Hnrpx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18521
VEGA: 15
HGNC: HGNC:8648
Homologene: 74536
Spag9
Name: sperm associated antigen 9
Synonyms: 4831406C20Rik, syd1, Mapk8ip4, 3110018C07Rik, 4733401I23Rik, JLP, JIP4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70834
Homologene: 2954
Prune2
Name: prune homolog 2
Synonyms: A230083H22Rik, A330102H22Rik, 6330414G02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 353211
VEGA: 19
Homologene: 18939
Paxbp1
Name: PAX3 and PAX7 binding protein 1
Synonyms: Pax3/7bp, 1810007M14Rik, Gcfc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67367
Homologene: 9604
Taf6l
Name: TATA-box binding protein associated factor 6 like
Synonyms: 2810417N14Rik, C530024J06Rik, PAF65A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225895
Homologene: 4728
Cd209b
Name: CD209b antigen
Synonyms: mSIGNR1, 1810030I22Rik, SIGNR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 69165
HGNC: HGNC:1641
Homologene: 84858
Clvs2
Name: clavesin 2
Synonyms: Rlbp1l2, A330019N05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215890
Homologene: 27894
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 77505
Homologene: 131117
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: FPC, tigmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Clcn3
Name: chloride channel, voltage-sensitive 3
Synonyms: Clc3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 12725
HGNC: HGNC:2021
Homologene: 20435
9130409I23Rik
Name: RIKEN cDNA 9130409I23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 619326
Homologene: 134522
Gm11639
Name: predicted gene 11639
Synonyms: Efcab15, Gm11639
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 105242472
Itgb4
Name: integrin beta 4
Synonyms: CD104
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 192897
HGNC: HGNC:6158
Homologene: 179
Sycp1
Name: synaptonemal complex protein 1
Synonyms: SCP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 20957
Homologene: 2389
Cacna1s
Name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Synonyms: fmd, muscle dysgenesis, DHPR alpha1s, mdg, Cchl1a3, sj, Cav1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12292
HGNC: HGNC:1397
Homologene: 37257
Ect2l
Name: epithelial cell transforming sequence 2 oncogene-like
Synonyms: Gm10331, C330021H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100045792
Homologene: 46005
Gxylt2
Name: glucoside xylosyltransferase 2
Synonyms: Glt8d4, LOC232313
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232313
Homologene: 16823
Kdm1b
Name: lysine (K)-specific demethylase 1B
Synonyms: 4632428N09Rik, Aof1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218214
Homologene: 14695
Bace1
Name: beta-site APP cleaving enzyme 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 23821
HGNC: HGNC:933
Homologene: 8014
Sspo
Name: SCO-spondin
Synonyms: Scospondin, C79529
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243369
Homologene: 45453
Gbp4
Name: guanylate binding protein 4
Synonyms: Mag-2, Mpa-2, Mpa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17472
Homologene: 128731
Pla2g4c
Name: phospholipase A2, group IVC (cytosolic, calcium-independent)
Synonyms: CPLA2-gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232889
HGNC: HGNC:9037
Homologene: 115256
Tsnaxip1
Name: translin-associated factor X (Tsnax) interacting protein 1
Synonyms: TXI1, 1700016K08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72236
Homologene: 10194
Gm10142
Name: predicted gene 10142
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100502921
VEGA: 10
Homologene: 135713
4933402N03Rik
Name: RIKEN cDNA 4933402N03 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233918
Homologene: 52852
Cyp4a12b
Name: cytochrome P450, family 4, subfamily a, polypeptide 12B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 13118
Homologene: 134044
Ttll10
Name: tubulin tyrosine ligase-like family, member 10
Synonyms: 4930595O22Rik, 4833412E22Rik, Ttll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 330010
Homologene: 51912
Vmn2r45
Name: vomeronasal 2, receptor 45
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100042810
Homologene: 113703
Ikbke
Name: inhibitor of kappaB kinase epsilon
Synonyms: IKKepsilon, IKK-i
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 56489
Homologene: 23168
Erp27
Name: endoplasmic reticulum protein 27
Synonyms: 1810047B09Rik, 1810033M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 69187
Homologene: 12303
Myrip
Name: myosin VIIA and Rab interacting protein
Synonyms: Slac2-c, A230081N12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 245049
Homologene: 9150
Creb3l3
Name: cAMP responsive element binding protein 3-like 3
Synonyms: CREB-H, D10Bur1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 208677
Homologene: 13080
Olfr1
Name: olfactory receptor 1
Synonyms: MOR135-13, GA_x6K02T2P1NL-3556334-3555390, I54
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258923
Homologene: 115482
Hexim2
Name: hexamethylene bis-acetamide inducible 2
Synonyms: 4933402L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71059
Homologene: 16946
Smim4
Name: small integral membrane protein 4
Synonyms: Gm41122, 2010107H07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66487
Ccnb1-ps
Name: cyclin B1, pseudogene
Synonyms: Gm5593
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 434175
HGNC: HGNC:1579
Homologene: 68982
Krtap19-9a
Name: keratin associated protein 19-9A
Synonyms: Gm9829, Krtap16-10a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 20,199,405 bp
  • T to A, chromosome 1 at 131,271,779 bp
  • A to G, chromosome 1 at 136,107,142 bp
  • T to A, chromosome 1 at 180,669,198 bp
  • G to A, chromosome 1 at 181,055,098 bp
  • A to T, chromosome 2 at 153,672,497 bp
  • G to A, chromosome 3 at 86,126,604 bp
  • A to C, chromosome 3 at 102,895,897 bp
  • C to T, chromosome 3 at 158,023,344 bp
  • T to A, chromosome 4 at 115,432,497 bp
  • T to A, chromosome 4 at 156,047,627 bp
  • A to C, chromosome 5 at 8,973,996 bp
  • A to G, chromosome 5 at 14,225,666 bp
  • A to G, chromosome 5 at 16,602,307 bp
  • G to A, chromosome 5 at 105,119,919 bp
  • C to A, chromosome 5 at 110,695,578 bp
  • T to A, chromosome 5 at 115,979,419 bp
  • T to C, chromosome 5 at 123,565,056 bp
  • A to T, chromosome 6 at 48,451,884 bp
  • C to A, chromosome 6 at 100,733,235 bp
  • A to T, chromosome 6 at 136,911,566 bp
  • T to A, chromosome 7 at 8,471,476 bp
  • T to A, chromosome 7 at 13,340,618 bp
  • T to C, chromosome 7 at 42,107,098 bp
  • A to G, chromosome 7 at 92,657,714 bp
  • C to A, chromosome 7 at 105,719,895 bp
  • T to C, chromosome 7 at 131,139,082 bp
  • T to C, chromosome 8 at 3,923,348 bp
  • T to C, chromosome 8 at 60,934,573 bp
  • A to G, chromosome 8 at 105,843,971 bp
  • T to A, chromosome 8 at 106,912,275 bp
  • G to A, chromosome 9 at 7,503,620 bp
  • A to G, chromosome 9 at 45,860,264 bp
  • T to A, chromosome 9 at 110,567,758 bp
  • A to G, chromosome 9 at 120,128,485 bp
  • G to A, chromosome 9 at 120,424,668 bp
  • A to T, chromosome 10 at 18,200,009 bp
  • G to T, chromosome 10 at 33,528,507 bp
  • C to A, chromosome 10 at 77,716,123 bp
  • C to T, chromosome 10 at 81,085,662 bp
  • AGCGGTCGTAGGC to AGC, chromosome 11 at 73,395,654 bp
  • T to A, chromosome 11 at 94,082,828 bp
  • G to A, chromosome 11 at 103,138,383 bp
  • T to A, chromosome 11 at 104,736,114 bp
  • C to T, chromosome 11 at 115,984,157 bp
  • A to G, chromosome 13 at 47,063,146 bp
  • G to T, chromosome 13 at 80,890,579 bp
  • A to G, chromosome 14 at 31,124,520 bp
  • T to A, chromosome 15 at 102,483,162 bp
  • T to C, chromosome 16 at 88,924,114 bp
  • G to T, chromosome 16 at 91,030,496 bp
  • C to A, chromosome 19 at 8,774,846 bp
  • A to G, chromosome 19 at 17,016,361 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5814 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043396-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.