Strain Name:
C57BL/6J-MtgxR5817Btlr
Stock Number:
043397-MU
Citation ID:
RRID:MMRRC_043397-MU
Other Names:
R5817 (G1)
Major Collection:

Gene Information

Ubn2
Name: ubinuclein 2
Synonyms: D130059P03Rik, 6030408G03Rik, 2900060J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320538
Homologene: 45564
Slc6a5
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Synonyms: Glyt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 104245
Homologene: 37901
Pomt1
Name: protein-O-mannosyltransferase 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 99011
HGNC: HGNC:9202
Homologene: 68548
Polr2f
Name: polymerase (RNA) II (DNA directed) polypeptide F
Synonyms: RNA Pol II, 1810060D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 69833
VEGA: 15
HGNC: HGNC:9193
Homologene: 7178
Ahcyl2
Name: S-adenosylhomocysteine hydrolase-like 2
Synonyms: 4631427C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 74340
Homologene: 69337
Zc3h13
Name: zinc finger CCCH type containing 13
Synonyms: 2600010B19Rik, 3110050K21Rik, 4930570G11Rik, C87618
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 67302
VEGA: 14
Agpat4
Name: 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
Synonyms: 1500003P24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 68262
Homologene: 69293
Rnf169
Name: ring finger protein 169
Synonyms: 2900057K09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 108937
Homologene: 47510
Slc25a17
Name: solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
Synonyms: 34kDa, PMP34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 20524
VEGA: 15
Homologene: 4637
Serpini1
Name: serine (or cysteine) peptidase inhibitor, clade I, member 1
Synonyms: Spi17, Ns, PI12, Neuroserpin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20713
HGNC: HGNC:8943
Homologene: 21045
Rbm26
Name: RNA binding motif protein 26
Synonyms: C230097K14Rik, 1700009P03Rik, Pro1777
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 74213
Homologene: 41468
Cc2d2a
Name: coiled-coil and C2 domain containing 2A
Synonyms: b2b1035Clo, 5730509K17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231214
Homologene: 18159
Cntn2
Name: contactin 2
Synonyms: TAG1, axonin, Tax, D130012K04Rik, TAG-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 21367
HGNC: HGNC:2172
Homologene: 3720
Pole
Name: polymerase (DNA directed), epsilon
Synonyms: pol-epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18973
HGNC: HGNC:9177
Homologene: 4539
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: p600, A930005E13Rik, 1810009A16Rik, LOC381562, D930005K06Rik, Zubr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 69116
Homologene: 10804
Gprc5c
Name: G protein-coupled receptor, family C, group 5, member C
Synonyms: 1110028I06Rik, 3200002M13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 70355
Homologene: 11099
Ncr1
Name: natural cytotoxicity triggering receptor 1
Synonyms: MAR1 (mouse activating receptor 1), Ly94, NKp46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17086
HGNC: HGNC:6731
Homologene: 3551
Chst15
Name: carbohydrate sulfotransferase 15
Synonyms: 4631426J05Rik, GalNAcS-6ST, MAd5, MAd5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 77590
Homologene: 8908
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: 4432416O06Rik, DHC2, b2b414Clo, Dnchc2, m407Asp, m152Asp, D030010H02Rik, D330044F14Rik, DHC1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Msh3
Name: mutS homolog 3
Synonyms: D13Em1, Rep-3, Rep3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17686
HGNC: HGNC:7326
Homologene: 1829
Abcf3
Name: ATP-binding cassette, sub-family F (GCN20), member 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 27406
HGNC: HGNC:72
Homologene: 22784
Shq1
Name: SHQ1 homolog (S. cerevisiae)
Synonyms: Grim-1, 2810403P18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 72171
Homologene: 31683
Casc4
Name: cancer susceptibility candidate 4
Synonyms: D130060C09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 319996
Homologene: 16310
Fam13b
Name: family with sequence similarity 13, member B
Synonyms: 2610024E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225358
VEGA: 18
HGNC: HGNC:1335
Homologene: 9585
Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Synonyms: 9830168K16Rik, Trrp7, TRPC7, LTRPC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 28240
Homologene: 20709
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545370
Homologene: 23741
Fam20a
Name: family with sequence similarity 20, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 208659
Homologene: 9719
Ceacam18
Name: carcinoembryonic antigen-related cell adhesion molecule 18
Synonyms: 2010110O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 72431
Homologene: 48111
Plekhh2
Name: pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 213556
VEGA: 17
Homologene: 35317
Ralgapa2
Name: Ral GTPase activating protein, alpha subunit 2 (catalytic)
Synonyms: AS250, RGC2, A230067G21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241694
Homologene: 28131
Ahnak2
Name: AHNAK nucleoprotein 2
Synonyms: LOC382643
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 100041194
Homologene: 131081
Aadacl4
Name: arylacetamide deacetylase like 4
Synonyms: Gm13177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 435815
Homologene: 82530
Arhgef5
Name: Rho guanine nucleotide exchange factor (GEF) 5
Synonyms: 2210412D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 54324
Homologene: 66300
Xcr1
Name: chemokine (C motif) receptor 1
Synonyms: Ccxcr1, C motif-1/lymphotactin receptor, GPR5, XCR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 23832
HGNC: HGNC:1625
Homologene: 21095
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: Mll2, Mll4, C430014K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Smc1b
Name: structural maintenance of chromosomes 1B
Synonyms: SMC1beta, Smc1l2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 140557
VEGA: 15
Homologene: 13786
Map1a
Name: microtubule-associated protein 1 A
Synonyms: Mtap1, 6330416M19Rik, Mtap-1, Mtap1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17754
HGNC: HGNC:6835
Homologene: 1778
Mical2
Name: microtubule associated monooxygenase, calponin and LIM domain containing 2
Synonyms: 5330438E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 320878
Homologene: 8760
Palmd
Name: palmdelphin
Synonyms: PALML, 4631423C22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 114301
Homologene: 9804
D630003M21Rik
Name: RIKEN cDNA D630003M21 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228846
Homologene: 18598
Vmn1r214
Name: vomeronasal 1 receptor 214
Synonyms: V1rh5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 171248
Homologene: 110880
Gmcl1
Name: germ cell-less, spermatogenesis associated 1
Synonyms: mglc-1, Gcl, 2810049L19Rik, Btbd13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 23885
Homologene: 8021
Gm5581
Name: predicted gene 5581
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
Pcsk7
Name: proprotein convertase subtilisin/kexin type 7
Synonyms: SPC7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 18554
VEGA: 9
HGNC: HGNC:8748
Homologene: 37955
Prag1
Name: PEAK1 related kinase activating pseudokinase 1
Synonyms: NACK, D8Ertd82e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244418
Homologene: 18256
Olfr1333
Name: olfactory receptor 1333
Synonyms: MOR259-6, GA_x6K02T2QD9B-18703033-18703986, MOR259-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 258265
Homologene: 134082
Trappc1
Name: trafficking protein particle complex 1
Synonyms: MUM2, BET5, D11Ertd172e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 245828
Homologene: 41425
Olfr926
Name: olfactory receptor 926
Synonyms: GA_x6K02T2PVTD-32573036-32573962, MOR171-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258811
VEGA: 9
HGNC: HGNC:8482
Homologene: 128215
Olfr586
Name: olfactory receptor 586
Synonyms: MOR8-2, MOR8-7, GA_x6K02T2PBJ9-5836380-5835439
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259115
Homologene: 131143
Olfr554
Name: olfactory receptor 554
Synonyms: MOR25-1, GA_x6K02T2PBJ9-5356887-5357840
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258322
Homologene: 105158
Qars
Name: glutaminyl-tRNA synthetase
Synonyms: 1200016L19Rik, 1110018N24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 97541
HGNC: HGNC:9751
Homologene: 133975
E330017A01Rik
Name: RIKEN cDNA E330017A01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224247
Homologene: 87248
Aqp7
Name: aquaporin 7
Synonyms: AQP7L, AQPap
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 11832
HGNC: HGNC:640
Homologene: 48000
Il6
Name: interleukin 6
Synonyms: Il-6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 16193
HGNC: HGNC:6018
Homologene: 502
Gm5454
Name: predicted gene 5454
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 432800
VEGA: 13
Gm21319
Name: predicted gene, 21319
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 100861908
Homologene: 103865
Gm11677
Name: predicted gene 11677
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 629967
Gm6619
Name: predicted gene 6619
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 102638913
Homologene: 136510
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 132,518,748 bp
  • T to A, chromosome 1 at 150,737,524 bp
  • A to T, chromosome 2 at 32,248,679 bp
  • G to A, chromosome 2 at 76,742,666 bp
  • A to T, chromosome 2 at 121,298,910 bp
  • T to A, chromosome 2 at 121,906,044 bp
  • G to A, chromosome 2 at 146,333,486 bp
  • A to G, chromosome 2 at 158,196,493 bp
  • T to A, chromosome 3 at 75,613,324 bp
  • T to C, chromosome 3 at 116,918,623 bp
  • G to A, chromosome 4 at 41,035,510 bp
  • T to G, chromosome 4 at 118,830,099 bp
  • A to G, chromosome 4 at 139,468,847 bp
  • A to G, chromosome 4 at 144,622,927 bp
  • A to G, chromosome 5 at 30,018,008 bp
  • G to A, chromosome 5 at 43,712,418 bp
  • G to A, chromosome 5 at 110,312,972 bp
  • G to A, chromosome 6 at 29,890,721 bp
  • C to A, chromosome 6 at 38,479,153 bp
  • G to A, chromosome 6 at 43,275,104 bp
  • A to G, chromosome 6 at 86,714,248 bp
  • A to G, chromosome 6 at 100,573,720 bp
  • A to G, chromosome 6 at 131,167,169 bp
  • A to G, chromosome 6 at 131,486,437 bp
  • T to A, chromosome 7 at 4,340,895 bp
  • A to G, chromosome 7 at 43,641,841 bp
  • C to A, chromosome 7 at 49,956,491 bp
  • A to G, chromosome 7 at 99,925,769 bp
  • A to G, chromosome 7 at 102,640,378 bp
  • A to T, chromosome 7 at 103,121,908 bp
  • A to T, chromosome 7 at 112,323,659 bp
  • A to T, chromosome 7 at 132,269,144 bp
  • G to A, chromosome 7 at 132,269,147 bp
  • A to C, chromosome 8 at 36,103,703 bp
  • T to A, chromosome 9 at 6,996,905 bp
  • A to G, chromosome 9 at 38,877,377 bp
  • A to T, chromosome 9 at 45,926,033 bp
  • C to T, chromosome 9 at 108,510,242 bp
  • C to T, chromosome 9 at 123,855,857 bp
  • C to A, chromosome 10 at 77,965,980 bp
  • A to T, chromosome 11 at 69,324,234 bp
  • T to A, chromosome 11 at 109,673,418 bp
  • C to T, chromosome 11 at 111,724,711 bp
  • T to A, chromosome 11 at 114,863,624 bp
  • G to T, chromosome 12 at 87,773,431 bp
  • A to T, chromosome 12 at 112,774,003 bp
  • T to G, chromosome 13 at 23,035,321 bp
  • A to T, chromosome 13 at 92,286,000 bp
  • T to A, chromosome 13 at 103,356,632 bp
  • A to G, chromosome 14 at 75,328,132 bp
  • T to C, chromosome 14 at 105,128,603 bp
  • T to C, chromosome 15 at 79,151,669 bp
  • G to A, chromosome 15 at 81,327,060 bp
  • A to G, chromosome 15 at 85,067,783 bp
  • A to T, chromosome 15 at 98,862,363 bp
  • T to C, chromosome 16 at 20,549,083 bp
  • T to C, chromosome 16 at 58,636,793 bp
  • C to T, chromosome 17 at 12,215,210 bp
  • A to G, chromosome 17 at 84,571,726 bp
  • T to C, chromosome 18 at 34,457,797 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5817 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043397-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.