Strain Name:
C57BL/6J-MtgxR5819Btlr
Stock Number:
043399-MU
Citation ID:
RRID:MMRRC_043399-MU
Other Names:
R5819 (G1)
Major Collection:

Gene Information

S1pr1
Name: sphingosine-1-phosphate receptor 1
Synonyms: S1P, Edg1, S1P1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 13609
HGNC: HGNC:3165
Homologene: 1071
Aggf1
Name: angiogenic factor with G patch and FHA domains 1
Synonyms: VG5Q, 2010009L17Rik, 2310029P06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 66549
Homologene: 41220
Kmt2c
Name: lysine (K)-specific methyltransferase 2C
Synonyms: HALR, E330008K23Rik, Mll3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231051
Homologene: 46480
Mga
Name: MAX gene associated
Synonyms: C130042M01Rik, Mga, D030062C11Rik, Mad5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 29808
Homologene: 49351
Phf14
Name: PHD finger protein 14
Synonyms: 1110001C23Rik, 5730446A07Rik, 4932409F11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 75725
Homologene: 8775
Mov10
Name: Mov10 RISC complex RNA helicase
Synonyms: Mov-10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 17454
HGNC: HGNC:7200
Homologene: 10365
Trp53bp1
Name: transformation related protein 53 binding protein 1
Synonyms: 53BP1, p53BP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 27223
Homologene: 4137
Cyfip1
Name: cytoplasmic FMR1 interacting protein 1
Synonyms: l(7)1Rl, E030028J09Rik, Sra-1, pl-1, Shyc, P140SRA-1, l7Rl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20430
Homologene: 22628
4932438A13Rik
Name: RIKEN cDNA 4932438A13 gene
Synonyms: FSA, Tweek
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229227
Homologene: 52105
Ruvbl1
Name: RuvB-like protein 1
Synonyms: 2510009G06Rik, Pontin52, Tip49a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 56505
Homologene: 37839
Chek1
Name: checkpoint kinase 1
Synonyms: Chk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 12649
HGNC: HGNC:1925
Homologene: 975
Rarb
Name: retinoic acid receptor, beta
Synonyms: RAR beta 2, Hap, RARbeta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 218772
VEGA: 14
HGNC: HGNC:9865
Homologene: 68100
Galnt4
Name: polypeptide N-acetylgalactosaminyltransferase 4
Synonyms: ppGaNTase-T4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 14426
HGNC: HGNC:4126
Homologene: 74511
Fubp1
Name: far upstream element (FUSE) binding protein 1
Synonyms: Fubp, Fubp4, 9530027K12Rik, FBP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 51886
HGNC: HGNC:4004
Homologene: 48253
Bod1l
Name: biorientation of chromosomes in cell division 1-like
Synonyms: A230054D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 665775
Homologene: 45109
Erc2
Name: ELKS/RAB6-interacting/CAST family member 2
Synonyms: ELKS2alpha, D14Ertd171e, CAST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 238988
Homologene: 69188
Zfyve27
Name: zinc finger, FYVE domain containing 27
Synonyms: 9530077C24Rik, protrudin, 2210011N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 319740
Homologene: 16939
Avil
Name: advillin
Synonyms: DOC6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11567
Homologene: 38200
Prkg1
Name: protein kinase, cGMP-dependent, type I
Synonyms: Prkgr1b, Prkg1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 19091
HGNC: HGNC:9414
Homologene: 55964
Ms4a10
Name: membrane-spanning 4-domains, subfamily A, member 10
Synonyms: 2010001N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 69826
Homologene: 11355
Ptprq
Name: protein tyrosine phosphatase, receptor type, Q
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237523
HGNC: HGNC:9679
Homologene: 83557
Abca4
Name: ATP-binding cassette, sub-family A (ABC1), member 4
Synonyms: Rim protein, D430003I15Rik, RmP, Abc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11304
HGNC: HGNC:34
Homologene: 298
Sbk3
Name: SH3 domain binding kinase family, member 3
Synonyms: LOC381835, Gm1078
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381835
Homologene: 82595
Efr3b
Name: EFR3 homolog B
Synonyms: C030014M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 668212
VEGA: 12
Homologene: 66195
Dclk1
Name: doublecortin-like kinase 1
Synonyms: CPG16, DCLK, 2810480F11Rik, 1700113D08Rik, Dcl, Click-I, Dcamkl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 13175
HGNC: HGNC:2700
Homologene: 130530
Htra1
Name: HtrA serine peptidase 1
Synonyms: RSPP11, Prss11, insulin-like growth factor binding protein 5 protease, HtrA1, L56
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56213
HGNC: HGNC:9476
Homologene: 31114
Rgl3
Name: ral guanine nucleotide dissociation stimulator-like 3
Synonyms: 1300003D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 71746
VEGA: 9
Homologene: 11363
Trnau1ap
Name: tRNA selenocysteine 1 associated protein 1
Synonyms: Trspap1, SECp43, 1110007F05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 71787
Homologene: 49509
Naaladl1
Name: N-acetylated alpha-linked acidic dipeptidase-like 1
Synonyms: LOC381204
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 381204
Homologene: 21124
Vmn2r13
Name: vomeronasal 2, receptor 13
Synonyms: Gm4867
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231589
Homologene: 129606
Osmr
Name: oncostatin M receptor
Synonyms: OSMRB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18414
HGNC: HGNC:8507
Homologene: 2972
Mettl21c
Name: methyltransferase like 21C
Synonyms: A530098C11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 433294
Homologene: 45916
Itprid1
Name: ITPR interacting domain containing 1
Synonyms: D530004J12Rik, Ccdc129
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232016
Homologene: 52344
Tmprss5
Name: transmembrane protease, serine 5 (spinesin)
Synonyms: spinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 80893
Homologene: 69471
Galc
Name: galactosylceramidase
Synonyms: Gacy, 2310068B06Rik, galactocerebrosidase, A930008M05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 14420
VEGA: 12
HGNC: HGNC:4115
Homologene: 124
Zfp777
Name: zinc finger protein 777
Synonyms: 2500002G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 72306
Homologene: 56721
Plppr4
Name: phospholipid phosphatase related 4
Synonyms: Lppr4, PRG-1, D3Bwg0562e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229791
Homologene: 8895
Olfr1275
Name: olfactory receptor 1275
Synonyms: GA_x6K02T2Q125-72283260-72282322, MOR245-18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 257980
Homologene: 79419
Tcp11
Name: t-complex protein 11
Synonyms: Tcp-11, D17Ken1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 21463
Homologene: 8433
Soga3
Name: SOGA family member 3
Synonyms: 6330407J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 67412
VEGA: 10
Homologene: 28227
Klhdc8b
Name: kelch domain containing 8B
Synonyms: 4931406O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 78267
Homologene: 45463
Gm17093
Name: predicted gene 17093
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Homologene: 128452
Optc
Name: opticin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269120
HGNC: HGNC:8158
Homologene: 8652
Ubqln3
Name: ubiquilin 3
Synonyms: 4933400K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 244178
Homologene: 9700
Scgb2b3
Name: secretoglobin, family 2B, member 3
Synonyms: Abpbg3, Gm4362
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043326
Homologene: 83171
Tdpoz8
Name: TD and POZ domain containing 8
Synonyms: Gm4858
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229571
Homologene: 130121
Smim8
Name: small integral membrane protein 8
Synonyms: 1810030N24Rik, 2810406B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66291
Homologene: 10708
Tas2r119
Name: taste receptor, type 2, member 119
Synonyms: mGR19, Tas2r19, mt2r19, T2R19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 57254
Homologene: 10480
Dfnb59
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 44,009,722 bp
  • T to C, chromosome 1 at 133,897,879 bp
  • A to G, chromosome 2 at 76,658,369 bp
  • A to T, chromosome 2 at 111,230,959 bp
  • A to C, chromosome 2 at 119,941,263 bp
  • G to A, chromosome 2 at 121,208,392 bp
  • A to T, chromosome 3 at 37,048,600 bp
  • G to A, chromosome 3 at 55,489,864 bp
  • A to G, chromosome 3 at 93,073,732 bp
  • C to T, chromosome 3 at 104,801,512 bp
  • G to T, chromosome 3 at 115,712,140 bp
  • T to A, chromosome 3 at 117,325,864 bp
  • A to T, chromosome 3 at 122,136,981 bp
  • T to C, chromosome 3 at 152,220,553 bp
  • TTTAATGAAGAGCT to TT, chromosome 4 at 34,771,261 bp
  • A to G, chromosome 4 at 132,325,210 bp
  • A to G, chromosome 5 at 25,409,132 bp
  • T to A, chromosome 5 at 41,832,605 bp
  • T to A, chromosome 5 at 109,174,100 bp
  • A to G, chromosome 6 at 11,997,252 bp
  • C to T, chromosome 6 at 48,037,588 bp
  • A to T, chromosome 6 at 55,897,891 bp
  • A to C, chromosome 6 at 88,483,115 bp
  • T to C, chromosome 7 at 4,969,997 bp
  • T to A, chromosome 7 at 31,360,214 bp
  • A to G, chromosome 7 at 55,879,151 bp
  • G to A, chromosome 7 at 104,141,467 bp
  • T to C, chromosome 7 at 130,981,739 bp
  • A to T, chromosome 9 at 21,981,602 bp
  • T to A, chromosome 9 at 36,710,405 bp
  • T to A, chromosome 9 at 49,114,479 bp
  • G to A, chromosome 9 at 108,451,062 bp
  • A to T, chromosome 10 at 29,197,273 bp
  • T to A, chromosome 10 at 99,110,030 bp
  • T to A, chromosome 10 at 107,719,883 bp
  • T to C, chromosome 10 at 127,009,998 bp
  • T to C, chromosome 12 at 3,992,965 bp
  • T to A, chromosome 12 at 98,216,261 bp
  • T to C, chromosome 13 at 95,351,621 bp
  • T to G, chromosome 14 at 16,443,820 bp
  • T to A, chromosome 14 at 28,141,369 bp
  • G to T, chromosome 14 at 44,521,529 bp
  • C to A, chromosome 15 at 6,815,787 bp
  • T to C, chromosome 15 at 32,177,306 bp
  • A to T, chromosome 17 at 28,069,236 bp
  • A to G, chromosome 19 at 6,109,654 bp
  • C to A, chromosome 19 at 10,968,690 bp
  • A to G, chromosome 19 at 31,585,672 bp
  • A to G, chromosome 19 at 42,183,496 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5819 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
043399-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.