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Availability & Fees Order this Strain
A floxed neo STOP cassette is inserted in the Hand1 5'UTR along with two point mutations:
Cre recombination removes the STOP cassette and allows for endogenous level of expression in tissues where Cre and Hand1 expression overlap.
Homozygous: lethal E9.5
Hetero/Hemizygous: viable and fertile
Cre-excised Phenotype: Undetermined
Colony Surveillance Program and Current Health Reports
Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.
Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.
The donor or their institution limits the distribution to non-profit institutions only.