Strain Name:
C57BL/6J-MtgxR5822Btlr
Stock Number:
044052-MU
Citation ID:
RRID:MMRRC_044052-MU
Other Names:
R5822 (G1)
Major Collection:

Gene Information

Ptprz1
Name: protein tyrosine phosphatase, receptor type Z, polypeptide 1
Synonyms: PTPbeta, DSD-1-PG, Ptprz, Ptpz, Rptpbeta, PTPzeta, RPTPz, phosphacan
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Utp20
Name: UTP20 small subunit processome component
Synonyms: DRIM, 3830408P06Rik, mDRIM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 70683
VEGA: 10
Homologene: 38373
Kdm5b
Name: lysine (K)-specific demethylase 5B
Synonyms: PLU-1, Jarid1b, 2010009J12Rik, Rb-Bp2, D1Ertd202e, Plu1, 2210016I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 75605
Homologene: 48448
Rictor
Name: RPTOR independent companion of MTOR, complex 2
Synonyms: 6030405M08Rik, D530039E11Rik, 4921505C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 78757
VEGA: 15
Homologene: 34317
Ppp6c
Name: protein phosphatase 6, catalytic subunit
Synonyms: 2310003C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67857
HGNC: HGNC:9323
Homologene: 68273
Ipo11
Name: importin 11
Synonyms: 1700081H05Rik, Ranbp11, E330021B14Rik, 2510001A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 76582
Homologene: 7089
Pan2
Name: PAN2 poly(A) specific ribonuclease subunit
Synonyms: 1200014O24Rik, Usp52
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103135
VEGA: 10
Homologene: 5918
Relch
Name: RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
Synonyms: 2310035C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227446
Homologene: 10834
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: D130015N03Rik, 2810449H11Rik, tbl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Rims2
Name: regulating synaptic membrane exocytosis 2
Synonyms: 2810036I15Rik, RIM2, Syt3-rs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 116838
VEGA: 15
Homologene: 81639
Pdik1l
Name: PDLIM1 interacting kinase 1 like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230809
Homologene: 36977
Ppp1r15a
Name: protein phosphatase 1, regulatory subunit 15A
Synonyms: Gadd34, Myd116
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17872
Homologene: 8639
Unc5b
Name: unc-5 netrin receptor B
Synonyms: Unc5h2, 6330415E02Rik, D10Bwg0792e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 107449
VEGA: 10
Homologene: 32538
Ddx11
Name: DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
Synonyms: KRG2, CHL1, CHLR1, 4732462I11Rik, essa15a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 320209
VEGA: 17
HGNC: HGNC:2736
Homologene: 68973
Tnnt1
Name: troponin T1, skeletal, slow
Synonyms: sTnT, Tnt, skeletal muscle slow-twitch TnT, ssTnT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 21955
Homologene: 20704
Chkb
Name: choline kinase beta
Synonyms: Chkl, CK/EK-beta, Chetk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12651
HGNC: HGNC:1938
Homologene: 88718
Fyb
Name: FYN binding protein
Synonyms: ADAP, FYB-120/130, B630013F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 23880
HGNC: HGNC:4036
Homologene: 22664
Stk32a
Name: serine/threonine kinase 32A
Synonyms: A930015B13Rik, YANK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 269019
VEGA: 18
Homologene: 65357
Trim80
Name: tripartite motif-containing 80
Synonyms: 4933422H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 432613
Homologene: 46325
Madd
Name: MAP-kinase activating death domain
Synonyms: Rab3 GEP, 9630059K23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228355
HGNC: HGNC:6766
Homologene: 14249
Cacna1s
Name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Synonyms: sj, DHPR alpha1s, muscle dysgenesis, fmd, Cchl1a3, mdg, Cav1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12292
HGNC: HGNC:1397
Homologene: 37257
Nr1h5
Name: nuclear receptor subfamily 1, group H, member 5
Synonyms: FXRB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 381463
Homologene: 131277
Map3k10
Name: mitogen-activated protein kinase kinase kinase 10
Synonyms: MKN28 kinase, MKN28 derived nonreceptor_type, serine/threonine kinase, Mlk2, mixed lineage kinase 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 269881
HGNC: HGNC:6849
Homologene: 1834
Olfr1260
Name: olfactory receptor 1260
Synonyms: GA_x6K02T2Q125-51409740-51410672, MOR232-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258983
HGNC: null
Homologene: 17455
Abca8a
Name: ATP-binding cassette, sub-family A (ABC1), member 8a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217258
HGNC: HGNC:38
Homologene: 131160
Zfp276
Name: zinc finger protein (C2H2 type) 276
Synonyms: D8Ertd370e, D8Ertd377e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 57247
Homologene: 10731
Mdga2
Name: MAM domain containing glycosylphosphatidylinositol anchor 2
Synonyms: 6720489L24Rik, Adp, Mdga2, 9330209L04Rik, Tg(Prnp-PFN1*G118V)838Kiaei, Mamdc1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 320772
Homologene: 45659
Ggn
Name: gametogenetin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243897
Homologene: 45139
Flnc
Name: filamin C, gamma
Synonyms: actin binding protein 280, Fln2, 1110055E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 68794
HGNC: HGNC:3756
Homologene: 37481
Kcnh7
Name: potassium voltage-gated channel, subfamily H (eag-related), member 7
Synonyms: 9330137I11Rik, Kv11.3, erg3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 170738
Homologene: 13249
Gbp3
Name: guanylate binding protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 55932
Homologene: 137329
Klc3
Name: kinesin light chain 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232943
Homologene: 14899
Cdh20
Name: cadherin 20
Synonyms: Cdh7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 23836
HGNC: HGNC:1760
Homologene: 8015
4930553M12Rik
Name: RIKEN cDNA 4930553M12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: null
VEGA: null
HGNC: null
Homologene: null
Olfr1352
Name: olfactory receptor 1352
Synonyms: GA_x6K02T2QGN0-2828447-2827518, MOR139-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 259074
HGNC: HGNC:8373
Homologene: 131141
Tmem217
Name: transmembrane protein 217
Synonyms: 4933413N12Rik, EG622644
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 71138
VEGA: 17
Homologene: 51671
Mogat2
Name: monoacylglycerol O-acyltransferase 2
Synonyms: Mgat2, DGAT2L5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233549
Homologene: 57020
Olfr117
Name: olfactory receptor 117
Synonyms: MOR256-33, GA_x6K02T2PSCP-2119438-2118485
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258263
HGNC: null
Homologene: 105876
Sdr39u1
Name: short chain dehydrogenase/reductase family 39U, member 1
Synonyms: 2310014G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 654795
VEGA: 14
Homologene: 69295
Olfr331
Name: olfactory receptor 331
Synonyms: MOR275-4, GA_x6K02T2NKPP-912840-913784
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 100502887
Homologene: 133015
Slc5a11
Name: solute carrier family 5 (sodium/glucose cotransporter), member 11
Synonyms: Kst1, 2010013B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233836
Homologene: 14184
B4galnt2
Name: beta-1,4-N-acetyl-galactosaminyl transferase 2
Synonyms: Galgt2, Dlb-1, Dlb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 14422
Homologene: 7329
Nkapl
Name: NFKB activating protein-like
Synonyms: 4921504I05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66707
Homologene: 57034
Gm12800
Name: predicted gene 12800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381535
HGNC: null
Homologene: null
Crp
Name: C-reactive protein, pentraxin-related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12944
HGNC: HGNC:2367
Homologene: 128039
Gm813
Name: predicted gene 813
Synonyms: LOC385656, LOC328695
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 328695
VEGA: 16
HGNC: null
Homologene: null
Bud23
Name: BUD23, rRNA methyltransferase and ribosome maturation factor
Synonyms: 1110003N24Rik, Wbscr22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 66138
Homologene: 5486
Cyp11b1
Name: cytochrome P450, family 11, subfamily b, polypeptide 1
Synonyms: Cyp11b-1, Cyp11b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 110115
Homologene: 106948
Npas2
Name: neuronal PAS domain protein 2
Synonyms: MOP4, bHLHe9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 18143
HGNC: HGNC:7895
Homologene: 1887
Serhl
Name: serine hydrolase-like
Synonyms: 1110019M09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 68607
Homologene: 65196
Olfr160
Name: olfactory receptor 160
Synonyms: MOR171-3, GA_x6K02T2PVTD-31389446-31388517, M72, MOR171-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 80706
HGNC: HGNC:8469
Homologene: 12726
Lst1
Name: leukocyte specific transcript 1
Synonyms: B144
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 16988
Homologene: null
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 39,347,566 bp
  • T to C, chromosome 1 at 104,934,098 bp
  • G to A, chromosome 1 at 105,718,856 bp
  • A to T, chromosome 1 at 134,588,773 bp
  • A to T, chromosome 1 at 136,112,078 bp
  • A to C, chromosome 1 at 172,698,068 bp
  • G to A, chromosome 2 at 39,200,052 bp
  • G to A, chromosome 2 at 62,716,238 bp
  • T to C, chromosome 2 at 89,978,443 bp
  • C to T, chromosome 2 at 91,152,533 bp
  • T to G, chromosome 3 at 102,949,328 bp
  • C to T, chromosome 3 at 142,566,478 bp
  • T to C, chromosome 4 at 88,868,359 bp
  • A to G, chromosome 4 at 101,910,243 bp
  • C to T, chromosome 4 at 134,287,163 bp
  • A to G, chromosome 5 at 135,063,921 bp
  • A to T, chromosome 6 at 23,001,445 bp
  • A to C, chromosome 6 at 29,459,430 bp
  • A to T, chromosome 7 at 4,516,346 bp
  • C to T, chromosome 7 at 19,395,799 bp
  • A to G, chromosome 7 at 27,656,734 bp
  • C to T, chromosome 7 at 29,172,556 bp
  • A to G, chromosome 7 at 45,523,303 bp
  • T to C, chromosome 7 at 99,219,905 bp
  • T to C, chromosome 7 at 123,252,431 bp
  • A to G, chromosome 8 at 123,255,718 bp
  • T to C, chromosome 9 at 37,711,791 bp
  • T to A, chromosome 9 at 66,445,612 bp
  • A to T, chromosome 10 at 60,772,527 bp
  • C to T, chromosome 10 at 78,984,189 bp
  • T to G, chromosome 10 at 88,817,285 bp
  • T to C, chromosome 10 at 128,320,380 bp
  • A to T, chromosome 11 at 58,501,638 bp
  • T to C, chromosome 11 at 95,866,159 bp
  • C to T, chromosome 11 at 110,030,879 bp
  • C to T, chromosome 11 at 115,447,921 bp
  • A to G, chromosome 12 at 66,655,335 bp
  • A to C, chromosome 13 at 21,468,423 bp
  • A to G, chromosome 13 at 106,848,418 bp
  • A to G, chromosome 14 at 55,897,739 bp
  • T to A, chromosome 15 at 6,663,226 bp
  • G to A, chromosome 15 at 6,794,006 bp
  • T to A, chromosome 15 at 39,476,490 bp
  • T to C, chromosome 15 at 74,836,821 bp
  • T to C, chromosome 15 at 83,116,327 bp
  • T to C, chromosome 15 at 89,429,512 bp
  • C to A, chromosome 16 at 58,615,712 bp
  • A to G, chromosome 17 at 29,526,555 bp
  • A to T, chromosome 17 at 35,188,383 bp
  • T to C, chromosome 17 at 37,660,231 bp
  • C to T, chromosome 17 at 66,129,981 bp
  • A to T, chromosome 18 at 43,313,487 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5822 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044052-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.