Strain Name:
C57BL/6J-MtgxR5837Btlr
Stock Number:
044057-MU
Citation ID:
RRID:MMRRC_044057-MU
Other Names:
R5837 (G1)
Major Collection:

Gene Information

Ptprz1
Name: protein tyrosine phosphatase, receptor type Z, polypeptide 1
Synonyms: RPTPz, DSD-1-PG, PTPzeta, PTPbeta, phosphacan, Ptprz, Ptpz, Rptpbeta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Npl
Name: N-acetylneuraminate pyruvate lyase
Synonyms: 0610033B02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 74091
Homologene: 12533
Bet1l
Name: Bet1 golgi vesicular membrane trafficking protein like
Synonyms: golgi SNARE, 2610021K23Rik, Gs15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 54399
Homologene: 10293
Ehmt1
Name: euchromatic histone methyltransferase 1
Synonyms: KMT1D, 9230102N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 77683
Homologene: 11698
Nudt1
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 1
Synonyms: Mth1, 8-oxo-7,8-dihydro-2'-dGTPase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 17766
HGNC: HGNC:8048
Homologene: 1839
Mef2d
Name: myocyte enhancer factor 2D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 17261
HGNC: HGNC:6997
Homologene: 4327
Mycbp2
Name: MYC binding protein 2, E3 ubiquitin protein ligase
Synonyms: Phr1, Pam, C130061D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105689
Homologene: 9005
Atf1
Name: activating transcription factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 11908
HGNC: HGNC:783
Homologene: 3790
Ccdc141
Name: coiled-coil domain containing 141
Synonyms: ENSMUSG00000075261, CAMDI, 2610301F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 545428
Homologene: 52149
Utp25
Name: UTP25 small subunit processome component
Synonyms: AA408296, Diexf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 215193
Homologene: 6170
Robo3
Name: roundabout guidance receptor 3
Synonyms: Robo3b, Robo3a, Rbig1, Rig1, Rig-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 19649
Homologene: 32119
Apob
Name: apolipoprotein B
Synonyms: apob-100, apob-48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Phrf1
Name: PHD and ring finger domains 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 101471
Homologene: 16377
Tnc
Name: tenascin C
Synonyms: TN, C130033P17Rik, Hxb, TN-C, cytotactin, tenascin-C, hexabrachion
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 21923
HGNC: HGNC:5318
Homologene: 55636
Treml1
Name: triggering receptor expressed on myeloid cells-like 1
Synonyms: TLT-1, 5430401J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 71326
VEGA: 17
Homologene: 52257
Ncoa2
Name: nuclear receptor coactivator 2
Synonyms: TIF2/GRIP-1, TIF2, Grip1, KAT13C, D1Ertd433e, TIF-2, SRC-2, glucocorticoid receptor-interacting protein 1, bHLHe75
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 17978
HGNC: HGNC:7669
Homologene: 4768
Lzic
Name: leucine zipper and CTNNBIP1 domain containing
Synonyms: 1810030J04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69151
Homologene: 12301
Nolc1
Name: nucleolar and coiled-body phosphoprotein 1
Synonyms: NOPP140, 3230402K17Rik, P130
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 70769
VEGA: 19
Ppp1r12c
Name: protein phosphatase 1, regulatory subunit 12C
Synonyms: 2410197A17Rik, Mbs85
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 232807
Homologene: 75071
Dact2
Name: dishevelled-binding antagonist of beta-catenin 2
Synonyms: Dpr2, 2900084M21Rik, Frd2, dapper2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240025
VEGA: 17
Homologene: 18237
Cep295
Name: centrosomal protein 295
Synonyms: 5830418K08Rik, LOC382128
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 319675
Homologene: 27936
Rapgef3
Name: Rap guanine nucleotide exchange factor (GEF) 3
Synonyms: 2310016P22Rik, Epac1, 9330170P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223864
Homologene: 21231
Dnajc13
Name: DnaJ heat shock protein family (Hsp40) member C13
Synonyms: D030002L11Rik, Rme8, LOC382100
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235567
Homologene: 13574
Rbp3
Name: retinol binding protein 3, interstitial
Synonyms: Rbp-3, Irbp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 19661
VEGA: 14
HGNC: HGNC:9921
Homologene: 9261
Wdr19
Name: WD repeat domain 19
Synonyms: C330027H04Rik, D330023L08Rik, Ift144, DYF2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 213081
Homologene: 11842
Trmt2a
Name: TRM2 tRNA methyltransferase 2A
Synonyms: Htf9c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 15547
Homologene: 7374
Ank1
Name: ankyrin 1, erythroid
Synonyms: Ank-1, pale
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11733
HGNC: HGNC:492
Homologene: 55427
Tnik
Name: TRAF2 and NCK interacting kinase
Synonyms: 1500031A17Rik, C630040K21Rik, C530008O15Rik, 4831440I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 665113
Homologene: 77943
Fbn1
Name: fibrillin 1
Synonyms: Fib-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14118
HGNC: HGNC:3603
Homologene: 30958
Ttn
Name: titin
Synonyms: D830007G01Rik, 2310057K23Rik, L56, shru, connectin, 2310074I15Rik, mdm, 2310036G12Rik, 1100001C23Rik, D330041I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Loxhd1
Name: lipoxygenase homology domains 1
Synonyms: sba, 1700096C21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 240411
Oc90
Name: otoconin 90
Synonyms: PLA2L, Ocn-95, Pla2ll
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 18256
HGNC: HGNC:8100
Homologene: 19021
Vmn2r116
Name: vomeronasal 2, receptor 116
Synonyms: EG619697, V2Rp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 619697
Homologene: 86604
Rabgap1l
Name: RAB GTPase activating protein 1-like
Synonyms: 5830411O09Rik, 8430421H08Rik, Hh1, 9630005B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 29809
Homologene: 8143
Vmn1r67
Name: vomeronasal 1 receptor 67
Synonyms: V1re10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 171263
Homologene: 128344
Lgi4
Name: leucine-rich repeat LGI family, member 4
Synonyms: clp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243914
Homologene: 16408
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 268527
Homologene: 8780
Olfr1491
Name: olfactory receptor 1491
Synonyms: GA_x6K02T2RE5P-4037809-4038768, MOR266-8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258342
Olfr376
Name: olfactory receptor 376
Synonyms: GA_x6K02T2P1NL-3535075-3536028, MOR135-12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 258924
Homologene: 133579
Ift140
Name: intraflagellar transport 140
Synonyms: Tce5, Wdtc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 106633
Homologene: 40979
Cyld
Name: CYLD lysine 63 deubiquitinase
Synonyms: 2010013M14Rik, C130039D01Rik, 2900009M21Rik, CYLD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74256
HGNC: HGNC:2584
Homologene: 9069
Abca2
Name: ATP-binding cassette, sub-family A (ABC1), member 2
Synonyms: Abc2, D2H0S1474E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11305
HGNC: HGNC:32
Homologene: 55590
Pcdhb9
Name: protocadherin beta 9
Synonyms: Pcdhb4C, PcdhbI
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93880
Homologene: 87124
Nudt19
Name: nudix (nucleoside diphosphate linked moiety X)-type motif 19
Synonyms: RP2-r, D7RP2e, D7Rp2, androgen regulated gene RP2, D7Rp2-r, D7Rp2-s, RP2-s
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 110959
Homologene: 13211
Pcdhb1
Name: protocadherin beta 1
Synonyms: PcdhbA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93872
HGNC: HGNC:8680
Homologene: 8348
Tmigd1
Name: transmembrane and immunoglobulin domain containing 1
Synonyms: 2010002A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 66601
Homologene: 41641
Phyhip
Name: phytanoyl-CoA hydroxylase interacting protein
Synonyms: PAHX-AP#1, PAHX-AP1, C630010D02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 105653
Homologene: 8847
Galnt6
Name: polypeptide N-acetylgalactosaminyltransferase 6
Synonyms: GalNAc-T6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 207839
HGNC: HGNC:4128
Homologene: 5218
Stoml2
Name: stomatin (Epb7.2)-like 2
Synonyms: SLP-2, 0610038F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66592
Homologene: 8389
Slco4c1
Name: solute carrier organic anion transporter family, member 4C1
Synonyms: OATP-M1, C330017E21Rik, SLC21A20, PRO2176, OATP4C1, OATP-H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227394
Homologene: 62654
Best1
Name: bestrophin 1
Synonyms: Vmd2, best macular dystrophy, mBest1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 24115
Homologene: 37895
Ssh3
Name: slingshot protein phosphatase 3
Synonyms: SSH-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 245857
VEGA: 19
Homologene: 32372
Zfp365
Name: zinc finger protein 365
Synonyms: DBZ, Su48
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216049
Homologene: 8975
Pramef6
Name: PRAME family member 6
Synonyms: Gm13099
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 195555
Homologene: 133722
Bpifa5
Name: BPI fold containing family A, member 5
Synonyms: 2310021H06Rik, 2310074B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 67135
Homologene: 12087
Zfp677
Name: zinc finger protein 677
Synonyms: A830058L05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 210503
Homologene: 138402
Olfr826
Name: olfactory receptor 826
Synonyms: MOR210-2, GA_x6K02T2PULF-11851623-11850682
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 258671
Homologene: 121503
Cyp2j13
Name: cytochrome P450, family 2, subfamily j, polypeptide 13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230459
Homologene: 138297
Zpbp2
Name: zona pellucida binding protein 2
Synonyms: 1700017D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69376
Homologene: 18892
Olfr1111
Name: olfactory receptor 1111
Synonyms: GA_x6K02T2Q125-48635468-48634530, MOR181-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258586
Homologene: 74238
Polr2h
Name: polymerase (RNA) II (DNA directed) polypeptide H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 245841
HGNC: HGNC:9195
Homologene: 4540
Commd7
Name: COMM domain containing 7
Synonyms: 2310010I22Rik, mU3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99311
Homologene: 24933
Psg17
Name: pregnancy specific glycoprotein 17
Synonyms: mmCGM5, Cea-2, Cea2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 26437
Homologene: 110989
Glra1
Name: glycine receptor, alpha 1 subunit
Synonyms: oscillator, nmf11, B230397M16Rik, ot
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14654
HGNC: HGNC:4326
Homologene: 20083
Gm10762
Name: predicted gene 10762
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Ilk
Name: integrin linked kinase
Synonyms: ESTM24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 16202
HGNC: HGNC:6040
Homologene: 3318
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 13,224,706 bp
  • C to T, chromosome 1 at 96,818,982 bp
  • T to C, chromosome 1 at 153,503,525 bp
  • T to C, chromosome 1 at 160,307,222 bp
  • A to T, chromosome 1 at 193,118,393 bp
  • A to G, chromosome 2 at 24,863,914 bp
  • G to A, chromosome 2 at 25,433,359 bp
  • T to C, chromosome 2 at 76,717,374 bp
  • G to T, chromosome 2 at 77,108,437 bp
  • A to T, chromosome 2 at 87,150,355 bp
  • A to T, chromosome 2 at 125,379,134 bp
  • C to T, chromosome 2 at 128,967,157 bp
  • A to G, chromosome 2 at 153,629,224 bp
  • A to G, chromosome 2 at 154,163,678 bp
  • A to T, chromosome 3 at 28,668,053 bp
  • A to G, chromosome 3 at 88,161,781 bp
  • G to T, chromosome 4 at 43,028,989 bp
  • T to A, chromosome 4 at 64,013,214 bp
  • A to T, chromosome 4 at 96,071,682 bp
  • A to G, chromosome 4 at 143,896,920 bp
  • G to T, chromosome 4 at 149,486,000 bp
  • A to G, chromosome 5 at 65,202,957 bp
  • A to G, chromosome 5 at 140,334,540 bp
  • T to C, chromosome 6 at 23,001,418 bp
  • C to A, chromosome 7 at 4,497,404 bp
  • T to C, chromosome 7 at 10,447,022 bp
  • T to A, chromosome 7 at 18,820,215 bp
  • C to T, chromosome 7 at 31,070,783 bp
  • T to C, chromosome 7 at 35,551,636 bp
  • T to C, chromosome 7 at 105,741,171 bp
  • C to A, chromosome 7 at 140,854,781 bp
  • C to G, chromosome 7 at 141,260,061 bp
  • A to G, chromosome 8 at 23,104,790 bp
  • G to A, chromosome 8 at 88,741,404 bp
  • T to A, chromosome 9 at 15,346,984 bp
  • T to A, chromosome 9 at 37,429,816 bp
  • T to A, chromosome 9 at 104,176,666 bp
  • A to T, chromosome 10 at 67,889,040 bp
  • A to T, chromosome 10 at 130,180,397 bp
  • G to T, chromosome 11 at 55,536,507 bp
  • A to G, chromosome 11 at 73,375,648 bp
  • A to G, chromosome 11 at 76,916,085 bp
  • G to A, chromosome 11 at 98,551,271 bp
  • A to G, chromosome 12 at 8,003,277 bp
  • C to T, chromosome 12 at 16,688,585 bp
  • C to A, chromosome 14 at 33,954,273 bp
  • C to A, chromosome 14 at 70,467,010 bp
  • C to A, chromosome 14 at 103,124,403 bp
  • T to C, chromosome 15 at 65,876,446 bp
  • C to T, chromosome 15 at 97,757,342 bp
  • T to A, chromosome 15 at 100,254,384 bp
  • G to A, chromosome 15 at 100,694,646 bp
  • C to T, chromosome 16 at 18,249,462 bp
  • T to A, chromosome 16 at 20,717,932 bp
  • A to G, chromosome 17 at 14,196,253 bp
  • A to T, chromosome 17 at 21,397,386 bp
  • T to C, chromosome 17 at 23,387,080 bp
  • A to G, chromosome 17 at 25,089,540 bp
  • A to G, chromosome 17 at 48,360,152 bp
  • T to C, chromosome 18 at 37,265,827 bp
  • C to A, chromosome 18 at 37,402,798 bp
  • A to G, chromosome 18 at 77,286,409 bp
  • T to C, chromosome 19 at 4,266,400 bp
  • T to A, chromosome 19 at 9,989,119 bp
  • T to A, chromosome 19 at 13,704,960 bp
  • T to C, chromosome 19 at 46,083,183 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5837 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044057-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.