Strain Name:
C57BL/6J-MtgxR5845Btlr
Stock Number:
044063-MU
Citation ID:
RRID:MMRRC_044063-MU
Other Names:
R5845 (G1)
Major Collection:

Gene Information

Ifngr2
Name: interferon gamma receptor 2
Synonyms: Ifgt, Ifgr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 15980
HGNC: HGNC:5440
Homologene: 4041
Cdon
Name: cell adhesion molecule-related/down-regulated by oncogenes
Synonyms: CDO, CAM-related/down-regulated by oncogenes
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 57810
Homologene: 22996
Sult6b1
Name: sulfotransferase family, cytosolic, 6B, member 1
Synonyms: 2410078J06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 73671
Homologene: 42242
Dock5
Name: dedicator of cytokinesis 5
Synonyms: rlc, 1110060D06Rik, lr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 68813
VEGA: 14
Homologene: 57016
Prkab1
Name: protein kinase, AMP-activated, beta 1 non-catalytic subunit
Synonyms: 1300015D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 19079
HGNC: HGNC:9378
Homologene: 38160
Ubr1
Name: ubiquitin protein ligase E3 component n-recognin 1
Synonyms: E3 alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22222
Homologene: 7582
Ubr7
Name: ubiquitin protein ligase E3 component n-recognin 7 (putative)
Synonyms: 5730410I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 66622
VEGA: 12
Homologene: 11998
Ccnf
Name: cyclin F
Synonyms: Fbxo1, CycF
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12449
VEGA: 17
HGNC: HGNC:1591
Homologene: 1335
Eif3c
Name: eukaryotic translation initiation factor 3, subunit C
Synonyms: 3230401O13Rik, Xs, Xsl, NIPIL(A3), 110kDa, Eif3s8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56347
HGNC: HGNC:3279
Homologene: 2781
Plxna4
Name: plexin A4
Synonyms: Plxa4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 243743
HGNC: HGNC:9102
Homologene: 77587
Rnd2
Name: Rho family GTPase 2
Synonyms: Rohn, Arhn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11858
Homologene: 21123
Septin2
Name: septin 2
Synonyms: Nedd5, Sept2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18000
HGNC: HGNC:7729
Homologene: 3243
Hs1bp3
Name: HCLS1 binding protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 58240
VEGA: 12
Homologene: 10980
Tmem131l
Name: transmembrane 131 like
Synonyms: D930015E06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229473
Homologene: 9057
Zswim4
Name: zinc finger SWIM-type containing 4
Synonyms: E130119J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 212168
Homologene: 18183
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 269700
Homologene: 28297
Trpv1
Name: transient receptor potential cation channel, subfamily V, member 1
Synonyms: capsaicin receptor, OTRPC1, VR-1, Vr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 193034
Homologene: 12920
Kcnk2
Name: potassium channel, subfamily K, member 2
Synonyms: TREK-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16526
HGNC: HGNC:6277
Homologene: 7794
Rasgrp3
Name: RAS, guanyl releasing protein 3
Synonyms: LOC240168
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 240168
VEGA: 17
Homologene: 15019
Acad10
Name: acyl-Coenzyme A dehydrogenase family, member 10
Synonyms: 2410021P16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 71985
Homologene: 49825
Fat3
Name: FAT atypical cadherin 3
Synonyms: LOC234973, D430038H04Rik, LOC382129, 9430076A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 270120
VEGA: 9
Homologene: 82252
Spta1
Name: spectrin alpha, erythrocytic 1
Synonyms: ihj, Spna-1, erythroid, Spna1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20739
Homologene: 74460
Mgam
Name: maltase-glucoamylase
Synonyms: 6030407P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232714
HGNC: HGNC:7043
Homologene: 130099
Slc26a6
Name: solute carrier family 26, member 6
Synonyms: B930010B04Rik, Pat1, CFEX
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 171429
Homologene: 99903
Dock10
Name: dedicator of cytokinesis 10
Synonyms: A630054M16Rik, Jr5, Zizimin3, ZIZ3, 9330153B10Rik, Jr4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 210293
Homologene: 45952
Uspl1
Name: ubiquitin specific peptidase like 1
Synonyms: E430026A01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 231915
Homologene: 4235
Fbn2
Name: fibrillin 2
Synonyms: Fib-2, Sne, sy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Fscb
Name: fibrous sheath CABYR binding protein
Synonyms: EG623046
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 623046
VEGA: 12
Homologene: 136275
Eml3
Name: echinoderm microtubule associated protein like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225898
VEGA: 19
Homologene: 27044
Trpm8
Name: transient receptor potential cation channel, subfamily M, member 8
Synonyms: Trp-p8, CMR1, TRPP8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 171382
Homologene: 23433
Kmt2d
Name: lysine (K)-specific methyltransferase 2D
Synonyms: Mll4, Mll2, C430014K11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 381022
HGNC: HGNC:7133
Homologene: 86893
Hrnr
Name: hornerin
Synonyms: 1110033K19Rik, S100a18, A530063N20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 68723
Homologene: 138092
Fcnb
Name: ficolin B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 14134
Homologene: 1518
Lrmp
Name: lymphoid-restricted membrane protein
Synonyms: D6Int7, D6Int8, Jaw1, D6Int5, D6Int4, D6Int3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 16970
HGNC: HGNC:6690
Homologene: 4483
Clca3b
Name: chloride channel accessory 3B
Synonyms: Clca4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229927
Homologene: 135610
Stoml2
Name: stomatin (Epb7.2)-like 2
Synonyms: SLP-2, 0610038F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 66592
Homologene: 8389
Ear2
Name: eosinophil-associated, ribonuclease A family, member 2
Synonyms: Rnase2, eosinophil-derived neurotoxin, liver
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 13587
Homologene: 40596
Olfr1129
Name: olfactory receptor 1129
Synonyms: MOR264-23, MOR264-9P, GA_x6K02T2Q125-49078087-49079031
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258111
Homologene: 133705
Vdr
Name: vitamin D (1,25-dihydroxyvitamin D3) receptor
Synonyms: Nr1i1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22337
Homologene: 37297
Cage1
Name: cancer antigen 1
Synonyms: CAGE1, 4933427I01Rik, Ctag3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 71213
Homologene: 18484
Mis18a
Name: MIS18 kinetochore protein A
Synonyms: 2810018N07Rik, 2610039C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 66578
HGNC: HGNC:1286
Homologene: 41294
Flacc1
Name: flagellum associated containing coiled-coil domains 1
Synonyms: 4933405P16Rik, Als2cr12, 4933425F06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 108812
Homologene: 51399
Amz2
Name: archaelysin family metallopeptidase 2
Synonyms: ESTM12
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 100503496
Ttc34
Name: tetratricopeptide repeat domain 34
Synonyms: B230396O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 242800
Homologene: 130480
Nsmce3
Name: NSE3 homolog, SMC5-SMC6 complex component
Synonyms: Ndnl2, HCA4, 5730494G16Rik, Mageg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 66647
HGNC: HGNC:7677
Homologene: 41520
Tmem221
Name: transmembrane protein 221
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 434325
Homologene: 110174
Tmem88
Name: transmembrane protein 88
Synonyms: 2600017H02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 67020
Homologene: 12073
Cyp2ab1
Name: cytochrome P450, family 2, subfamily ab, polypeptide 1
Synonyms: EG224044
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224044
Homologene: 120487
Gm6124
Name: predicted gene 6124
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 620018
Homologene: 45597
Zfp853
Name: zinc finger protein 853
Synonyms: LOC330230
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330230
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 58,667,778 bp
  • C to T, chromosome 1 at 80,505,742 bp
  • T to C, chromosome 1 at 88,328,180 bp
  • T to A, chromosome 1 at 93,499,035 bp
  • T to A, chromosome 1 at 174,241,096 bp
  • T to C, chromosome 1 at 189,277,721 bp
  • C to T, chromosome 2 at 28,079,621 bp
  • T to C, chromosome 2 at 87,576,023 bp
  • T to C, chromosome 2 at 120,904,005 bp
  • A to G, chromosome 3 at 83,940,553 bp
  • A to T, chromosome 3 at 93,332,637 bp
  • G to A, chromosome 3 at 144,825,316 bp
  • T to G, chromosome 4 at 43,030,008 bp
  • T to C, chromosome 4 at 154,865,472 bp
  • A to T, chromosome 5 at 116,024,160 bp
  • T to A, chromosome 5 at 121,307,524 bp
  • A to T, chromosome 5 at 121,626,083 bp
  • C to T, chromosome 5 at 143,288,669 bp
  • C to T, chromosome 5 at 149,193,960 bp
  • A to T, chromosome 6 at 32,237,776 bp
  • T to A, chromosome 6 at 40,675,323 bp
  • G to A, chromosome 6 at 145,171,666 bp
  • A to G, chromosome 7 at 39,219,875 bp
  • A to G, chromosome 7 at 64,872,188 bp
  • T to C, chromosome 7 at 126,564,755 bp
  • T to A, chromosome 8 at 71,555,144 bp
  • T to A, chromosome 8 at 84,217,242 bp
  • G to A, chromosome 9 at 16,377,210 bp
  • G to T, chromosome 9 at 35,457,466 bp
  • T to G, chromosome 9 at 108,862,083 bp
  • C to G, chromosome 11 at 69,397,678 bp
  • T to C, chromosome 11 at 73,240,581 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • T to C, chromosome 11 at 109,433,929 bp
  • A to G, chromosome 12 at 8,336,275 bp
  • A to G, chromosome 12 at 64,472,784 bp
  • C to T, chromosome 12 at 102,766,312 bp
  • T to A, chromosome 13 at 38,015,706 bp
  • G to A, chromosome 14 at 44,103,161 bp
  • A to T, chromosome 14 at 67,841,101 bp
  • C to A, chromosome 15 at 97,869,766 bp
  • G to A, chromosome 15 at 98,852,109 bp
  • C to T, chromosome 16 at 20,312,332 bp
  • A to G, chromosome 16 at 90,721,634 bp
  • T to C, chromosome 16 at 91,555,059 bp
  • C to A, chromosome 17 at 24,240,793 bp
  • A to T, chromosome 17 at 75,503,147 bp
  • A to C, chromosome 17 at 78,894,630 bp
  • T to C, chromosome 18 at 58,053,768 bp
  • A to G, chromosome 19 at 8,939,218 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5845 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044063-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.