Strain Name:
C57BL/6J-MtgxR5847Btlr
Stock Number:
044065-MU
Citation ID:
RRID:MMRRC_044065-MU
Other Names:
R5847 (G1)
Major Collection:

Gene Information

Mtmr3
Name: myotubularin related protein 3
Synonyms: 1700092A20Rik, FYVE-DSP1, ZFYVE10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 74302
HGNC: HGNC:7451
Homologene: 23662
Wnk1
Name: WNK lysine deficient protein kinase 1
Synonyms: EG406236, Hsn2, 6430573H23Rik, Prkwnk1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232341
Homologene: 14253
Cnot2
Name: CCR4-NOT transcription complex, subunit 2
Synonyms: 2600016M12Rik, 2810470K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 72068
HGNC: HGNC:7878
Homologene: 40953
Wwp1
Name: WW domain containing E3 ubiquitin protein ligase 1
Synonyms: SDRP1, 8030445B08Rik, AIP5, Tiul1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 107568
Homologene: 21385
Rheb
Name: Ras homolog enriched in brain
Synonyms: Rheb1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19744
Homologene: 123916
Dock4
Name: dedicator of cytokinesis 4
Synonyms: EST N28122, 6330411N01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 238130
VEGA: 12
Homologene: 56680
Ppp1r10
Name: protein phosphatase 1, regulatory subunit 10
Synonyms: 2610025H06Rik, D17Ertd808e, PNUTS
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 52040
HGNC: HGNC:9284
Homologene: 2033
Dek
Name: DEK oncogene (DNA binding)
Synonyms: D13H6S231E, 1810019E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 110052
HGNC: HGNC:2768
Homologene: 2593
Wwc1
Name: WW, C2 and coiled-coil domain containing 1
Synonyms: Kibra
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 211652
Homologene: 69180
Cacng3
Name: calcium channel, voltage-dependent, gamma subunit 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 54376
HGNC: HGNC:1407
Homologene: 4767
Trappc3
Name: trafficking protein particle complex 3
Synonyms: 1110058K12Rik, Bet3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 27096
Homologene: 6399
Epg5
Name: ectopic P-granules autophagy protein 5 homolog (C. elegans)
Synonyms: 5430411K18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 100502841
VEGA: 18
Homologene: 14575
Zfp868
Name: zinc finger protein 868
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234362
Homologene: 74376
Ncr1
Name: natural cytotoxicity triggering receptor 1
Synonyms: MAR1 (mouse activating receptor 1), Ly94, NKp46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 17086
HGNC: HGNC:6731
Homologene: 3551
Snx9
Name: sorting nexin 9
Synonyms: SDP1, SH3PX1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 66616
VEGA: 17
Homologene: 49454
Tox4
Name: TOX high mobility group box family member 4
Synonyms: 5730589K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 268741
Homologene: 8889
Trim11
Name: tripartite motif-containing 11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 94091
Homologene: 14225
Tmem51
Name: transmembrane protein 51
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 214359
Homologene: 9966
Pde12
Name: phosphodiesterase 12
Synonyms: E430028B21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 211948
Homologene: 14272
Dact2
Name: dishevelled-binding antagonist of beta-catenin 2
Synonyms: Dpr2, 2900084M21Rik, dapper2, Frd2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 240025
VEGA: 17
Homologene: 18237
Nphp3
Name: nephronophthisis 3 (adolescent)
Synonyms: nephrocystin 3, pcy, D330020E01Rik, 3632410F03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 74025
HGNC: HGNC:7907
Homologene: 32697
Rpgrip1l
Name: Rpgrip1-like
Synonyms: fantom, Ftm, 1700047E16Rik, Nphp8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244585
Homologene: 18296
Akap3
Name: A kinase (PRKA) anchor protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 11642
HGNC: HGNC:373
Homologene: 4688
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: FPC, tigmin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Arhgap20
Name: Rho GTPase activating protein 20
Synonyms: 6530403F17Rik, A530023E23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 244867
Homologene: 18938
Tgfbi
Name: transforming growth factor, beta induced
Synonyms: Beta-ig, bIG-h3, 68kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 21810
VEGA: 13
Homologene: 37294
Evc2
Name: EvC ciliary complex subunit 2
Synonyms: Ellis van Creveld syndrome 2, limbin, Lbn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 68525
Homologene: 17117
Mgam
Name: maltase-glucoamylase
Synonyms: 6030407P20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232714
HGNC: HGNC:7043
Homologene: 130099
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Myoc
Name: myocilin
Synonyms: TIGR, GLC1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17926
HGNC: HGNC:7610
Homologene: 220
Olfr1097
Name: olfactory receptor 1097
Synonyms: GA_x6K02T2Q125-48376288-48375341, MOR206-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258840
Homologene: 37005
Ttc23l
Name: tetratricopeptide repeat domain 23-like
Synonyms: 4930401A09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 75777
Homologene: 44907
Tbc1d2b
Name: TBC1 domain family, member 2B
Synonyms: 1810061M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 67016
Homologene: 56694
Idh3b
Name: isocitrate dehydrogenase 3 (NAD+) beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 170718
HGNC: HGNC:5385
Homologene: 5035
Doxl1
Name: diamine oxidase-like protein 1
Synonyms: 1600015I10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 69761
Homologene: 79726
Edar
Name: ectodysplasin-A receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 13608
HGNC: HGNC:2895
Homologene: 7699
Pbld1
Name: phenazine biosynthesis-like protein domain containing 1
Synonyms: Pbld, 0610038K03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 68371
VEGA: 10
Homologene: 41470
Cyp2c37
Name: cytochrome P450, family 2. subfamily c, polypeptide 37
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 13096
Homologene: 137231
Ccdc158
Name: coiled-coil domain containing 158
Synonyms: 4932413O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 320696
Homologene: 18560
Adgrg6
Name: adhesion G protein-coupled receptor G6
Synonyms: LOC215798, Gpr126, DREG, 1190004A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 215798
Homologene: 10724
Ccdc63
Name: coiled-coil domain containing 63
Synonyms: 4921511C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330188
Homologene: 45136
Iqca1l
Name: IQ motif containing with AAA domain 1 like
Synonyms: 4931409K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231045
Homologene: 18602
Ctnna2
Name: catenin (cadherin associated protein), alpha 2
Synonyms: Catna, Catna2, alpha(N)-catenin, alpha N-catenin, chp
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12386
HGNC: HGNC:2510
Homologene: 68394
Alpk1
Name: alpha-kinase 1
Synonyms: 8430410J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71481
Homologene: 11849
Olfr168
Name: olfactory receptor 168
Synonyms: GA_x54KRFPKG5P-15979009-15978071, MOR271-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258354
Homologene: 128057
Zfp354b
Name: zinc finger protein 354B
Synonyms: Kid2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 27274
Homologene: 32187
Olfr678
Name: olfactory receptor 678
Synonyms: MOR32-5, GA_x6K02T2PBJ9-7698491-7699432
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258753
Homologene: 27254
Pdxk
Name: pyridoxal (pyridoxine, vitamin B6) kinase
Synonyms: 2310036D04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 216134
HGNC: HGNC:8819
Homologene: 2731
Zfp24
Name: zinc finger protein 24
Synonyms: Zfp191, KOX17, 5033419P20Rik, ZF-12, 3526401F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 59057
Homologene: 5068
Zfp853
Name: zinc finger protein 853
Synonyms: LOC330230
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 330230
Igkv8-24
Name: immunoglobulin kappa chain variable 8-24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 677858
Scgb2b33
Name: secretoglobin, family 2B, member 33
Synonyms: Abpbg33, Gm9161
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 668419
Homologene: 83171
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to A, chromosome 1 at 20,374,736 bp
  • A to G, chromosome 1 at 162,639,367 bp
  • A to C, chromosome 2 at 86,890,332 bp
  • A to T, chromosome 2 at 130,284,028 bp
  • A to G, chromosome 3 at 127,680,074 bp
  • A to T, chromosome 4 at 19,662,174 bp
  • A to T, chromosome 4 at 126,273,978 bp
  • A to G, chromosome 4 at 142,032,035 bp
  • A to T, chromosome 5 at 24,544,166 bp
  • T to A, chromosome 5 at 24,807,069 bp
  • C to T, chromosome 5 at 37,404,724 bp
  • G to T, chromosome 5 at 92,627,480 bp
  • T to A, chromosome 5 at 122,116,845 bp
  • C to T, chromosome 5 at 143,288,669 bp
  • T to C, chromosome 6 at 40,684,055 bp
  • T to A, chromosome 6 at 48,933,478 bp
  • A to T, chromosome 6 at 70,216,972 bp
  • A to T, chromosome 6 at 76,973,837 bp
  • C to A, chromosome 6 at 119,992,408 bp
  • T to A, chromosome 6 at 126,865,558 bp
  • A to T, chromosome 7 at 4,344,574 bp
  • T to C, chromosome 7 at 33,112,814 bp
  • A to T, chromosome 7 at 105,069,857 bp
  • T to C, chromosome 7 at 122,762,309 bp
  • T to C, chromosome 8 at 69,611,652 bp
  • T to C, chromosome 8 at 91,304,985 bp
  • G to A, chromosome 9 at 51,824,976 bp
  • C to A, chromosome 9 at 90,209,724 bp
  • A to G, chromosome 9 at 104,003,037 bp
  • T to A, chromosome 10 at 14,426,777 bp
  • T to A, chromosome 10 at 58,603,179 bp
  • A to T, chromosome 10 at 63,076,414 bp
  • G to T, chromosome 10 at 78,445,038 bp
  • T to C, chromosome 10 at 116,527,946 bp
  • A to G, chromosome 11 at 4,482,925 bp
  • A to G, chromosome 11 at 35,867,326 bp
  • T to C, chromosome 11 at 50,923,216 bp
  • T to A, chromosome 11 at 58,990,593 bp
  • CAGTTGCTTAAA to CA, chromosome 11 at 66,095,240 bp
  • A to G, chromosome 12 at 40,621,251 bp
  • A to G, chromosome 13 at 47,101,601 bp
  • G to A, chromosome 13 at 56,636,605 bp
  • A to G, chromosome 14 at 26,665,631 bp
  • A to G, chromosome 14 at 52,286,784 bp
  • T to C, chromosome 15 at 10,537,596 bp
  • A to T, chromosome 16 at 19,530,326 bp
  • C to A, chromosome 17 at 5,924,621 bp
  • A to G, chromosome 17 at 14,199,188 bp
  • A to G, chromosome 17 at 35,926,847 bp
  • G to A, chromosome 18 at 24,018,038 bp
  • T to C, chromosome 18 at 78,030,055 bp
  • C to T, chromosome 19 at 40,011,732 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5847 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044065-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.