Strain Name:
C57BL/6J-MtgxR5881Btlr
Stock Number:
044085-MU
Citation ID:
RRID:MMRRC_044085-MU
Other Names:
R5881 (G1)
Major Collection:

Gene Information

Mc3r
Name: melanocortin 3 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 17201
HGNC: HGNC:6931
Homologene: 7412
Dnmt1
Name: DNA methyltransferase (cytosine-5) 1
Synonyms: MTase, Cxxc9, MommeD2, Dnmt1o
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 13433
VEGA: 9
HGNC: HGNC:2976
Homologene: 124071
Ylpm1
Name: YLP motif containing 1
Synonyms: ZAP, A930013E17Rik, Zap3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 56531
Homologene: 87707
Cisd1
Name: CDGSH iron sulfur domain 1
Synonyms: Zcd1, D10Ertd214e, mitoNEET
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 52637
Homologene: 10212
Ppa2
Name: pyrophosphatase (inorganic) 2
Synonyms: 1110013G13Rik, Sid6306
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 74776
Homologene: 134244
Ybx3
Name: Y box protein 3
Synonyms: Dpba, Csda, oxyR, dbpA, MSY4, MSY3, Yb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 56449
HGNC: HGNC:2428
Homologene: 2708
Ank3
Name: ankyrin 3, epithelial
Synonyms: Ank-3, AnkG, Ankyrin-G, Ankyrin-3, 2900054D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 11735
HGNC: HGNC:494
Homologene: 56908
Rab27a
Name: RAB27A, member RAS oncogene family
Synonyms: 4933437C11Rik, 2410003M20Rik, 2210402C08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 11891
HGNC: HGNC:9766
Homologene: 3069
Vipas39
Name: VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
Synonyms: SPE-39, Vipar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 104799
VEGA: 12
Homologene: 41464
Rnf34
Name: ring finger protein 34
Synonyms: phafin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 80751
Homologene: 11839
Gprin3
Name: GPRIN family member 3
Synonyms: C030038J10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 243385
Homologene: 52334
Adam11
Name: a disintegrin and metallopeptidase domain 11
Synonyms: Mdc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11488
HGNC: HGNC:189
Homologene: 7614
Rala
Name: v-ral simian leukemia viral oncogene A (ras related)
Synonyms: 3010001O15Rik, Rasl1, Ral
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 56044
HGNC: HGNC:9839
Homologene: 3942
Tent2
Name: terminal nucleotidyltransferase 2
Synonyms: 8030446C20Rik, Papd4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 100715
VEGA: 13
Homologene: 44022
Boc
Name: biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 117606
Homologene: 32819
Epgn
Name: epithelial mitogen
Synonyms: 2310069M11Rik, epigen
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 71920
Homologene: 19527
Jmjd6
Name: jumonji domain containing 6
Synonyms: PSR, 5730436I23Rik, Ptdsr, PtdSerR
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 107817
Homologene: 9046
Necap1
Name: NECAP endocytosis associated 1
Synonyms: 1200016B17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 67602
Homologene: 22902
Ice1
Name: interactor of little elongation complex ELL subunit 1
Synonyms: BC018507
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218333
VEGA: 13
Homologene: 18902
Papln
Name: papilin, proteoglycan-like sulfated glycoprotein
Synonyms: E030033C16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 170721
Homologene: 71541
Hmcn1
Name: hemicentin 1
Synonyms: LOC240793, EG545370
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545370
Homologene: 23741
Mccc1
Name: methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
Synonyms: 2310058B18Rik, MCCalpha, MCCA, 1810045E08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 72039
HGNC: HGNC:6936
Homologene: 10603
Scn7a
Name: sodium channel, voltage-gated, type VII, alpha
Synonyms: Nav2.3, 1110034K09Rik, Nax, Scn6a, Nav2, NaG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 20272
Homologene: 55706
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
Homologene: 110349
Dock10
Name: dedicator of cytokinesis 10
Synonyms: Zizimin3, Jr4, Jr5, A630054M16Rik, 9330153B10Rik, ZIZ3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 210293
Homologene: 45952
C8a
Name: complement component 8, alpha polypeptide
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230558
HGNC: HGNC:1352
Homologene: 472
Abi3
Name: ABI gene family, member 3
Synonyms: 2210414K06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66610
Homologene: 9505
Rabgap1l
Name: RAB GTPase activating protein 1-like
Synonyms: 5830411O09Rik, 8430421H08Rik, Hh1, 9630005B12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 29809
Homologene: 8143
Tdrd5
Name: tudor domain containing 5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 214575
Homologene: 18312
Ros1
Name: Ros1 proto-oncogene
Synonyms: c-ros, Ros-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 19886
Homologene: 2207
Phldb3
Name: pleckstrin homology like domain, family B, member 3
Synonyms: EG232970, Gm10102
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232970
Homologene: 109375
Eml3
Name: echinoderm microtubule associated protein like 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225898
VEGA: 19
Homologene: 27044
Tie1
Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Synonyms: TIE, tie-1, D430008P04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 21846
Homologene: 3957
Myo1f
Name: myosin IF
Synonyms: C330006B10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 17916
HGNC: HGNC:7600
Homologene: 56276
Ddx60
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234311
Homologene: 23031
Samd9l
Name: sterile alpha motif domain containing 9-like
Synonyms: ESTM25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 209086
HGNC: HGNC:1349
Homologene: 7707
Lrit2
Name: leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
Synonyms: A930010E21Rik, Lrrc22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239038
VEGA: 14
Homologene: 18292
Slc6a20a
Name: solute carrier family 6 (neurotransmitter transporter), member 20A
Synonyms: A730081N20Rik, Xtrp3s1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 102680
Homologene: 10625
Ppef2
Name: protein phosphatase, EF hand calcium-binding domain 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 19023
HGNC: HGNC:9244
Homologene: 55959
Pkd1l2
Name: polycystic kidney disease 1 like 2
Synonyms: 1700126L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 76645
Homologene: 124481
Dsel
Name: dermatan sulfate epimerase-like
Synonyms: DS-epi2, 9330132E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 319901
Homologene: 12964
Olfr1271
Name: olfactory receptor 1271
Synonyms: MOR227-5, GA_x6K02T2Q125-51620802-51619885
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 258789
Rgl2
Name: ral guanine nucleotide dissociation stimulator-like 2
Synonyms: Rgt2, Rlf, KE1.5, Rab2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 19732
HGNC: HGNC:9769
Homologene: 3494
Olfr725
Name: olfactory receptor 725
Synonyms: MOR246-7_p, MOR246-3, GA_x6K02T2PMLR-5725741-5724776
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258314
Homologene: 44957
Hspa14
Name: heat shock protein 14
Synonyms: NST-1, Hsp70-4, HSP70L1, 70kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 50497
Homologene: 74307
Desi2
Name: desumoylating isopeptidase 2
Synonyms: 5830417C01Rik, Pppde1, Fam152a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 78825
Homologene: 56741
Olfr65
Name: olfactory receptor 65
Synonyms: 5'[b]3, MOR1-2, GA_x6K02T2PBJ9-6634906-6633983
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18365
Homologene: 66459
Ces3a
Name: carboxylesterase 3A
Synonyms: Es-male carboxylesterase, Es31
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 382053
HGNC: HGNC:1865
Homologene: 84407
Entpd2
Name: ectonucleoside triphosphate diphosphohydrolase 2
Synonyms: Cd39l1, NTPDase2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12496
HGNC: HGNC:3364
Homologene: 20333
Ager
Name: advanced glycosylation end product-specific receptor
Synonyms: RAGE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 11596
HGNC: HGNC:320
Homologene: 883
Commd8
Name: COMM domain containing 8
Synonyms: IMAGE:1958590, D5Buc26e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 27784
Homologene: 9873
Hils1
Name: histone H1-like protein in spermatids 1
Synonyms: TISP64
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 54388
Homologene: 56818
Gm10436
Name: predicted gene 10436
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 100039315
VEGA: 12
Homologene: 103830
Grifin
Name: galectin-related inter-fiber protein
Synonyms: E130101O17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 77998
HGNC: HGNC:4577
Homologene: 14293
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 80,560,923 bp
  • A to T, chromosome 1 at 111,859,438 bp
  • A to G, chromosome 1 at 150,630,327 bp
  • A to T, chromosome 1 at 156,294,500 bp
  • A to T, chromosome 1 at 160,342,113 bp
  • A to G, chromosome 1 at 178,237,913 bp
  • A to G, chromosome 2 at 3,498,170 bp
  • A to C, chromosome 2 at 25,400,812 bp
  • T to C, chromosome 2 at 66,675,526 bp
  • G to T, chromosome 2 at 82,984,441 bp
  • A to T, chromosome 2 at 90,266,442 bp
  • T to C, chromosome 2 at 172,249,172 bp
  • A to G, chromosome 3 at 35,964,382 bp
  • A to T, chromosome 3 at 133,330,439 bp
  • T to A, chromosome 4 at 104,853,932 bp
  • T to C, chromosome 4 at 118,475,603 bp
  • A to T, chromosome 5 at 72,162,764 bp
  • A to G, chromosome 5 at 91,028,363 bp
  • A to T, chromosome 5 at 92,250,529 bp
  • A to T, chromosome 5 at 122,864,083 bp
  • G to T, chromosome 5 at 140,563,587 bp
  • T to C, chromosome 6 at 3,372,716 bp
  • T to C, chromosome 6 at 59,354,786 bp
  • T to A, chromosome 6 at 122,881,544 bp
  • A to C, chromosome 6 at 131,368,488 bp
  • T to C, chromosome 7 at 24,626,722 bp
  • T to A, chromosome 7 at 103,906,676 bp
  • A to T, chromosome 8 at 62,037,070 bp
  • G to A, chromosome 8 at 105,050,566 bp
  • A to G, chromosome 8 at 116,997,582 bp
  • A to G, chromosome 9 at 20,952,717 bp
  • G to A, chromosome 9 at 73,085,039 bp
  • A to C, chromosome 9 at 123,641,708 bp
  • C to T, chromosome 10 at 52,181,798 bp
  • C to T, chromosome 10 at 69,986,830 bp
  • A to T, chromosome 10 at 71,336,414 bp
  • A to G, chromosome 11 at 94,968,163 bp
  • A to C, chromosome 11 at 95,834,387 bp
  • A to T, chromosome 11 at 95,834,388 bp
  • A to C, chromosome 11 at 102,773,810 bp
  • C to T, chromosome 11 at 116,839,856 bp
  • A to G, chromosome 12 at 83,771,878 bp
  • A to T, chromosome 12 at 85,042,125 bp
  • G to A, chromosome 12 at 87,251,807 bp
  • A to G, chromosome 12 at 88,176,341 bp
  • A to G, chromosome 13 at 17,893,161 bp
  • T to C, chromosome 13 at 70,606,501 bp
  • A to T, chromosome 13 at 93,175,738 bp
  • G to T, chromosome 14 at 37,072,235 bp
  • G to A, chromosome 14 at 50,034,987 bp
  • A to G, chromosome 16 at 44,490,651 bp
  • A to G, chromosome 17 at 33,576,653 bp
  • G to A, chromosome 17 at 33,580,285 bp
  • A to G, chromosome 17 at 33,932,717 bp
  • G to T, chromosome 17 at 34,600,077 bp
  • T to C, chromosome 19 at 8,933,443 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5881 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044085-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.