Strain Name:
C57BL/6J-MtgxR5916Btlr
Stock Number:
044113-MU
Citation ID:
RRID:MMRRC_044113-MU
Other Names:
R5916 (G1)
Major Collection:

Gene Information

Utrn
Name: utrophin
Synonyms: Dmdl, G-utrophin, DRP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22288
VEGA: 10
Homologene: 21398
Ntrk2
Name: neurotrophic tyrosine kinase, receptor, type 2
Synonyms: trkB, Tkrb, C030027L06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18212
VEGA: 13
HGNC: HGNC:8032
Homologene: 4504
Colgalt2
Name: collagen beta(1-O)galactosyltransferase 2
Synonyms: Glt25d2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269132
Homologene: 22865
Agt
Name: angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
Synonyms: Aogen, Serpina8, angiotensin precursor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11606
HGNC: HGNC:333
Homologene: 14
Mga
Name: MAX gene associated
Synonyms: D030062C11Rik, C130042M01Rik, Mad5, Mga
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 29808
Homologene: 49351
U2af2
Name: U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 22185
Homologene: 110853
Tbc1d22a
Name: TBC1 domain family, member 22a
Synonyms: D15Ertd781e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223754
VEGA: 15
HGNC: HGNC:1309
Homologene: 105406
Trappc12
Name: trafficking protein particle complex 12
Synonyms: D930014A20Rik, Ttc15, CGI-87
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 217449
VEGA: 12
Homologene: 34805
Resf1
Name: retroelement silencing factor 1
Synonyms: GET, 2810474O19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67246
Homologene: 19251
Heatr1
Name: HEAT repeat containing 1
Synonyms: B130016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 217995
VEGA: 13
Homologene: 34562
Rad51b
Name: RAD51 paralog B
Synonyms: mREC2, Rad51l1, Rad51b, R51H2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 19363
VEGA: 12
HGNC: HGNC:9822
Homologene: 50190
Focad
Name: focadhesin
Synonyms: BC057079
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230393
Homologene: 9842
Atp13a1
Name: ATPase type 13A1
Synonyms: catp, Cgi152, Atp13a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 170759
VEGA: 8
Homologene: 5791
Nufip1
Name: nuclear fragile X mental retardation protein interacting protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 27275
VEGA: 14
HGNC: HGNC:8057
Homologene: 8216
Zkscan5
Name: zinc finger with KRAB and SCAN domains 5
Synonyms: hKraba1, Zfp95
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22757
Homologene: 8734
Scube2
Name: signal peptide, CUB domain, EGF-like 2
Synonyms: 4932442O19Rik, ICRFP703B1614Q5.1, Cegf1, ICRFP703N2430Q5.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 56788
Homologene: 36383
Fzd3
Name: frizzled class receptor 3
Synonyms: Fz3, D930050A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 14365
HGNC: HGNC:4041
Homologene: 23004
Tent2
Name: terminal nucleotidyltransferase 2
Synonyms: 8030446C20Rik, Papd4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 100715
VEGA: 13
Homologene: 44022
Vsir
Name: V-set immunoregulatory receptor
Synonyms: 4632428N05Rik, PD-1H, Dies1, VISTA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 74048
Homologene: 81923
Il17re
Name: interleukin 17 receptor E
Synonyms: Il25r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 57890
Homologene: 17109
Il1f9
Name: interleukin 1 family, member 9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 215257
Homologene: 49595
Lrrn2
Name: leucine rich repeat protein 2, neuronal
Synonyms: 5730406J09Rik, NLRR-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 16980
Homologene: 21274
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: D330044F14Rik, b2b414Clo, Dnchc2, m152Asp, D030010H02Rik, m407Asp, DHC2, DHC1b, 4432416O06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Hmcn2
Name: hemicentin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 665700
Homologene: 90772
Rfx8
Name: regulatory factor X 8
Synonyms: 4933400N17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 619289
Homologene: 82436
Rpgrip1l
Name: Rpgrip1-like
Synonyms: 1700047E16Rik, Nphp8, fantom, Ftm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244585
Homologene: 18296
Dchs1
Name: dachsous cadherin related 1
Synonyms: 3110041P15Rik, C130033F22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233651
Homologene: 2771
Ptprq
Name: protein tyrosine phosphatase, receptor type, Q
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 237523
HGNC: HGNC:9679
Homologene: 83557
Naip5
Name: NLR family, apoptosis inhibitory protein 5
Synonyms: Naip-rs3, Lgn1, Birc1e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17951
HGNC: HGNC:7634
Homologene: 113589
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: HL19, LOC380889, DHC3, HL-19, 4921531P07Rik, Dnahc12, Hdhc3, DLP12, Dnahc7l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Fmnl3
Name: formin-like 3
Synonyms: 2700073B04Rik, Wbp3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 22379
Homologene: 69101
Mx1
Name: MX dynamin-like GTPase 1
Synonyms: myxovirus (influenza) resistance 1 polypeptide, Mx, Mx-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17857
Clrn1
Name: clarin 1
Synonyms: A130002D11Rik, USH3, clarin-1, Ush3a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229320
Homologene: 17738
Junb
Name: jun B proto-oncogene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16477
HGNC: HGNC:6205
Homologene: 7390
Lrriq1
Name: leucine-rich repeats and IQ motif containing 1
Synonyms: 4930503E15Rik, Gm1557, LOC380658
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 74978
Homologene: 46007
Npepl1
Name: aminopeptidase-like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228961
Homologene: 11647
Olfr1308
Name: olfactory receptor 1308
Synonyms: MOR245-22, GA_x6K02T2Q125-73008844-73007882
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258258
Homologene: 45797
Olfr108
Name: olfactory receptor 108
Synonyms: MOR156-5, GA_x6K02T2PSCP-1893605-1894534
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 258457
Homologene: 44985
Megf6
Name: multiple EGF-like-domains 6
Synonyms: 2600001P17Rik, Egfl3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230971
HGNC: HGNC:3232
Homologene: 45412
Tmcc2
Name: transmembrane and coiled-coil domains 2
Synonyms: 1110063G11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68875
Homologene: 8905
Olfr417
Name: olfactory receptor 417
Synonyms: MOR267-11, GA_x6K02T2P20D-20787051-20786119
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258238
Homologene: 17358
Dsc3
Name: desmocollin 3
Synonyms: 5430426I24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 13507
VEGA: 18
HGNC: HGNC:3037
Homologene: 1462
Sipa1l2
Name: signal-induced proliferation-associated 1 like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 244668
Homologene: 18956
Asb2
Name: ankyrin repeat and SOCS box-containing 2
Synonyms: 1110008E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 65256
Homologene: 69202
Herc6
Name: hect domain and RLD 6
Synonyms: 1700121D12Rik, CEB1, 2510038N07Rik, 4930427L17Rik, Herc5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 67138
Homologene: 70768
Zscan29
Name: zinc finger SCAN domains 29
Synonyms: Zfp690
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99334
Homologene: 17586
Abcc1
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Synonyms: Mdrap, MRP, Abcc1b, Abcc1a, Mrp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 17250
HGNC: HGNC:51
Homologene: 133779
Ano3
Name: anoctamin 3
Synonyms: B230324K02Rik, Tmem16c
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228432
Homologene: 57147
Marchf1
Name: membrane associated ring-CH-type finger 1
Synonyms: 2900024D24Rik, March1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72925
Homologene: 113749
Fam243
Name: family with sequence similarity 243
Synonyms: 4930563D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 75328
VEGA: 16
Homologene: 57100
Glb1l3
Name: galactosidase, beta 1 like 3
Synonyms: 4921509F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 70893
Homologene: 72240
Adam3
Name: a disintegrin and metallopeptidase domain 3 (cyritestin)
Synonyms: tMDC, Cyrn1, Taz83, ADAM3, Taz83
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11497
HGNC: HGNC:209
Homologene: 69052
Ccdc173
Name: coiled-coil domain containing 173
Synonyms: 4930578N16Rik, 4930525K21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 75051
Homologene: 18989
Atxn7l2
Name: ataxin 7-like 2
Synonyms: 2610528J18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 72522
Homologene: 17728
Ocln
Name: occludin
Synonyms: Ocl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 18260
HGNC: HGNC:8104
Homologene: 1905
Tpp1
Name: tripeptidyl peptidase I
Synonyms: Cln2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12751
HGNC: HGNC:2073
Homologene: 335
Olfr544
Name: olfactory receptor 544
Synonyms: GA_x6K02T2PBJ9-5206624-5205620, MOR42-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 257926
Homologene: 133590
Slc35f1
Name: solute carrier family 35, member F1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215085
Homologene: 33552
Erich3
Name: glutamate rich 3
Synonyms: 4922501L14Rik, 5031409G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 209601
Homologene: 27877
Bambi
Name: BMP and activin membrane-bound inhibitor
Synonyms: 2610003H06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 68010
VEGA: 18
Homologene: 8215
Gm13177
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Gm20654
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 39,688,619 bp
  • C to T, chromosome 1 at 132,357,691 bp
  • T to A, chromosome 1 at 132,937,800 bp
  • T to A, chromosome 1 at 152,504,122 bp
  • A to T, chromosome 1 at 174,369,132 bp
  • T to G, chromosome 2 at 24,192,794 bp
  • T to A, chromosome 2 at 31,396,139 bp
  • A to T, chromosome 2 at 69,789,462 bp
  • A to T, chromosome 2 at 110,681,836 bp
  • A to G, chromosome 2 at 111,960,830 bp
  • T to A, chromosome 2 at 119,964,312 bp
  • G to T, chromosome 2 at 121,164,037 bp
  • G to T, chromosome 2 at 174,121,544 bp
  • T to C, chromosome 3 at 58,846,362 bp
  • T to C, chromosome 3 at 108,205,662 bp
  • A to T, chromosome 3 at 154,695,823 bp
  • T to C, chromosome 4 at 88,357,541 bp
  • A to T, chromosome 4 at 144,622,980 bp
  • A to G, chromosome 4 at 154,249,425 bp
  • T to A, chromosome 5 at 145,205,302 bp
  • G to A, chromosome 6 at 57,646,203 bp
  • T to A, chromosome 6 at 113,470,123 bp
  • C to T, chromosome 6 at 149,326,578 bp
  • A to T, chromosome 7 at 5,079,180 bp
  • G to A, chromosome 7 at 102,484,379 bp
  • A to T, chromosome 7 at 105,749,380 bp
  • C to A, chromosome 7 at 105,759,166 bp
  • A to G, chromosome 7 at 109,831,724 bp
  • A to T, chromosome 8 at 24,684,539 bp
  • G to T, chromosome 8 at 66,387,111 bp
  • T to A, chromosome 8 at 69,807,098 bp
  • T to C, chromosome 8 at 84,977,876 bp
  • C to A, chromosome 8 at 91,252,913 bp
  • A to T, chromosome 8 at 124,563,858 bp
  • A to T, chromosome 8 at 125,468,573 bp
  • A to G, chromosome 9 at 7,102,309 bp
  • T to C, chromosome 9 at 26,854,736 bp
  • T to A, chromosome 10 at 12,665,051 bp
  • C to A, chromosome 10 at 52,933,221 bp
  • C to T, chromosome 10 at 60,358,037 bp
  • G to A, chromosome 10 at 103,221,382 bp
  • A to T, chromosome 10 at 107,523,513 bp
  • A to G, chromosome 12 at 28,691,514 bp
  • C to T, chromosome 12 at 79,325,082 bp
  • G to T, chromosome 12 at 103,323,876 bp
  • T to C, chromosome 13 at 12,434,471 bp
  • A to G, chromosome 13 at 58,808,729 bp
  • T to C, chromosome 13 at 93,175,547 bp
  • A to C, chromosome 13 at 100,222,701 bp
  • T to G, chromosome 13 at 100,506,179 bp
  • T to A, chromosome 14 at 26,706,918 bp
  • G to A, chromosome 14 at 65,202,729 bp
  • T to C, chromosome 14 at 76,134,900 bp
  • A to T, chromosome 15 at 75,451,178 bp
  • A to G, chromosome 15 at 86,214,608 bp
  • A to T, chromosome 15 at 99,321,828 bp
  • G to T, chromosome 16 at 14,465,142 bp
  • T to A, chromosome 16 at 92,320,671 bp
  • T to C, chromosome 16 at 97,451,733 bp
  • C to T, chromosome 17 at 37,445,679 bp
  • A to G, chromosome 18 at 3,511,463 bp
  • T to C, chromosome 18 at 19,987,020 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5916 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044113-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.