Strain Name:
C57BL/6J-MtgxR5920Btlr
Stock Number:
044117-MU
Citation ID:
RRID:MMRRC_044117-MU
Other Names:
R5920 (G1)
Major Collection:

Gene Information

Dbh
Name: dopamine beta hydroxylase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 13166
HGNC: HGNC:2689
Homologene: 615
Kmt2e
Name: lysine (K)-specific methyltransferase 2E
Synonyms: 1810033J14Rik, 9530077A04Rik, D230038D11Rik, Mll5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 69188
Homologene: 18822
Ktn1
Name: kinectin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 16709
HGNC: HGNC:6467
Homologene: 7397
Zfp532
Name: zinc finger protein 532
Synonyms: C530030I18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 328977
Homologene: 138627
Uaca
Name: uveal autoantigen with coiled-coil domains and ankyrin repeats
Synonyms: 2700059D02Rik, nucling
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 72565
VEGA: 9
Homologene: 74297
Cenpc1
Name: centromere protein C1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12617
HGNC: HGNC:1854
Homologene: 1371
Kdm2b
Name: lysine (K)-specific demethylase 2B
Synonyms: Fbxl10, Jhdm1b, Cxxc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 30841
Homologene: 13069
Ptpn1
Name: protein tyrosine phosphatase, non-receptor type 1
Synonyms: PTP1B, PTP-1B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 19246
HGNC: HGNC:9642
Homologene: 2119
Sdha
Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Synonyms: FP, SDHF, SDH2, 2310034D06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 66945
Homologene: 3073
Immt
Name: inner membrane protein, mitochondrial
Synonyms: P87, P87/89, P89, HMP, 1700082C19Rik, Micos60, mitofilin, D830041H16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 76614
HGNC: HGNC:6047
Homologene: 38234
Atp13a1
Name: ATPase type 13A1
Synonyms: catp, Cgi152, Atp13a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 170759
VEGA: 8
Homologene: 5791
Calcr
Name: calcitonin receptor
Synonyms: Clr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12311
HGNC: HGNC:1440
Homologene: 1320
Chd2
Name: chromodomain helicase DNA binding protein 2
Synonyms: 2810040A01Rik, 5630401D06Rik, 2810013C04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244059
HGNC: HGNC:1917
Homologene: 37462
Adam18
Name: a disintegrin and metallopeptidase domain 18
Synonyms: Adam27, Dtgn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 13524
HGNC: HGNC:196
Homologene: 74941
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: Pcn, Plc, perlecan, per
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Usp33
Name: ubiquitin specific peptidase 33
Synonyms: 9830169D19Rik, Vdu1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 170822
Homologene: 8996
Il16
Name: interleukin 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16170
HGNC: HGNC:5980
Homologene: 18157
Pkd2l2
Name: polycystic kidney disease 2-like 2
Synonyms: TRPP5, Polycystin - L2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 53871
VEGA: 18
HGNC: HGNC:9012
Homologene: 22812
Col24a1
Name: collagen, type XXIV, alpha 1
Synonyms: 5430404K19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 71355
Homologene: 65061
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
Homologene: 110349
2010300C02Rik
Name: RIKEN cDNA 2010300C02 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 72097
Homologene: 19208
Myoc
Name: myocilin
Synonyms: TIGR, GLC1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 17926
HGNC: HGNC:7610
Homologene: 220
Mast3
Name: microtubule associated serine/threonine kinase 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 546071
Homologene: 66191
Aox1
Name: aldehyde oxidase 1
Synonyms: Aox2, Aox-2, retinal oxidase, Aox-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 11761
HGNC: HGNC:553
Homologene: 68165
Ak9
Name: adenylate kinase 9
Synonyms: Akd1, Akd2, Gm7127, LOC215946
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 633979
Homologene: 67934
Rasal3
Name: RAS protein activator like 3
Synonyms: A430107D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 320484
Homologene: 18901
Frmd4a
Name: FERM domain containing 4A
Synonyms: 2700017I06Rik, C230040M21Rik, Gm13190
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 209630
Homologene: 9971
Olfr517
Name: olfactory receptor 517
Synonyms: GA_x6K02T2PBJ9-11199311-11198367, MOR268-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258136
Homologene: 79413
Plcl2
Name: phospholipase C-like 2
Synonyms: Plce2, PRIP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224860
VEGA: 17
HGNC: HGNC:9064
Homologene: 9052
Phykpl
Name: 5-phosphohydroxy-L-lysine phospholyase
Synonyms: Agxt2l2, 2900006B13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 72947
Homologene: 75268
Per3
Name: period circadian clock 3
Synonyms: 2810049O06Rik, mPer3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18628
HGNC: HGNC:8847
Homologene: 7886
Tbc1d31
Name: TBC1 domain family, member 31
Synonyms: D330013L20Rik, Wdr67, LOC210544
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 210544
Homologene: 17089
Cfap43
Name: cilia and flagella associated protein 43
Synonyms: 4930428C11Rik, Wdr96, D19Ertd652e, 4930463G05Rik, 4632415N18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 100048534
Homologene: 36425
Usp9y
Name: ubiquitin specific peptidase 9, Y chromosome
Synonyms: Fafl2, Dffry
Type: Gene
Species: Mus musculus (mouse)
Chromosome: Y
Alteration at locus: Chemically Induced
NCBI: 107868
Homologene: 68408
Ttc26
Name: tetratricopeptide repeat domain 26
Synonyms: hpy, hop, hydrocephalic-polydactyl, 9430097H08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 264134
Homologene: 11786
Otulinl
Name: OTU deubiquitinase with linear linkage specificity like
Synonyms: Fam105a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223433
VEGA: 15
Homologene: 41302
Eif2b5
Name: eukaryotic translation initiation factor 2B, subunit 5 epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 224045
HGNC: HGNC:3261
Homologene: 2903
Casd1
Name: CAS1 domain containing 1
Synonyms: Cast1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 213819
Homologene: 11287
Mrgpre
Name: MAS-related GPR, member E
Synonyms: C130069N09Rik, MrgE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 244238
Homologene: 18469
Dcdc2c
Name: doublecortin domain containing 2C
Synonyms: 1110015M06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68511
Homologene: 131934
Ttc12
Name: tetratricopeptide repeat domain 12
Synonyms: E330017O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235330
Homologene: 32375
Gm15800
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
Hmha1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 37,637,981 bp
  • T to C, chromosome 1 at 58,049,472 bp
  • C to T, chromosome 1 at 162,639,559 bp
  • T to G, chromosome 2 at 4,333,116 bp
  • T to C, chromosome 2 at 27,177,231 bp
  • C to T, chromosome 2 at 82,988,508 bp
  • A to G, chromosome 2 at 167,971,748 bp
  • G to T, chromosome 3 at 145,428,230 bp
  • G to T, chromosome 3 at 152,374,683 bp
  • A to T, chromosome 4 at 137,553,782 bp
  • G to A, chromosome 4 at 151,012,450 bp
  • A to G, chromosome 5 at 23,499,442 bp
  • T to A, chromosome 5 at 86,020,910 bp
  • C to T, chromosome 5 at 121,308,271 bp
  • G to C, chromosome 5 at 122,880,296 bp
  • G to A, chromosome 6 at 3,722,994 bp
  • T to A, chromosome 6 at 4,641,853 bp
  • A to G, chromosome 6 at 38,412,070 bp
  • T to A, chromosome 6 at 71,863,196 bp
  • A to G, chromosome 7 at 73,537,312 bp
  • G to A, chromosome 7 at 83,652,344 bp
  • C to A, chromosome 7 at 108,868,688 bp
  • T to A, chromosome 7 at 143,781,728 bp
  • T to C, chromosome 8 at 24,674,075 bp
  • G to A, chromosome 8 at 69,800,096 bp
  • T to C, chromosome 8 at 70,787,933 bp
  • T to C, chromosome 9 at 49,453,333 bp
  • T to A, chromosome 9 at 60,869,603 bp
  • T to A, chromosome 10 at 41,420,676 bp
  • T to A, chromosome 10 at 80,029,131 bp
  • A to C, chromosome 11 at 51,602,795 bp
  • T to C, chromosome 12 at 28,535,537 bp
  • A to G, chromosome 13 at 74,326,925 bp
  • G to T, chromosome 14 at 47,724,024 bp
  • T to A, chromosome 15 at 27,664,356 bp
  • C to A, chromosome 15 at 57,942,558 bp
  • G to T, chromosome 16 at 20,498,944 bp
  • G to A, chromosome 17 at 32,395,169 bp
  • G to T, chromosome 17 at 50,608,675 bp
  • A to T, chromosome 18 at 34,430,773 bp
  • G to A, chromosome 18 at 65,644,350 bp
  • A to G, chromosome 19 at 47,760,896 bp
  • A to G, chromosome Y at 1,316,730 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5920 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044117-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.