Strain Name:
C57BL/6J-MtgxR5927Btlr
Stock Number:
044122-MU
Citation ID:
RRID:MMRRC_044122-MU
Other Names:
R5927 (G1)
Major Collection:

Gene Information

Acadm
Name: acyl-Coenzyme A dehydrogenase, medium chain
Synonyms: MCAD
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 11364
HGNC: HGNC:89
Homologene: 3
Elavl4
Name: ELAV like RNA binding protein 4
Synonyms: Hud
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15572
HGNC: HGNC:3315
Homologene: 40729
Dysf
Name: dysferlin
Synonyms: 2310004N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 26903
HGNC: HGNC:3097
Homologene: 20748
Kcmf1
Name: potassium channel modulatory factor 1
Synonyms: 1700094M07Rik, clone DEBT-91, Pmcf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74287
Homologene: 99845
Cdk11b
Name: cyclin-dependent kinase 11B
Synonyms: Cdc2l2, Cdc2l1, CDK11-p46, PITSLRE proteins, CDK11-p110, CDK11-p58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 12537
Homologene: 22416
P4htm
Name: prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
Synonyms: P4h-tm, 4933406E20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 74443
Homologene: 41765
Stk11ip
Name: serine/threonine kinase 11 interacting protein
Synonyms: LIP1, LKB1IP, 1200014D22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71728
Homologene: 12406
Elp3
Name: elongator acetyltransferase complex subunit 3
Synonyms: 2610507P14Rik, KAT9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 74195
VEGA: 14
Homologene: 7105
Psme4
Name: proteasome (prosome, macropain) activator subunit 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103554
Homologene: 113742
Atad5
Name: ATPase family, AAA domain containing 5
Synonyms: C130052G03Rik, LOC237877
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237877
Homologene: 32611
Sin3b
Name: transcriptional regulator, SIN3B (yeast)
Synonyms: 2810430C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 20467
Homologene: 81810
Xpo1
Name: exportin 1
Synonyms: Crm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 103573
Homologene: 2554
Kif15
Name: kinesin family member 15
Synonyms: 3110023M17Rik, Knsl7, HKLP2, 3930402I10Rik, N-10 kinesin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 209737
VEGA: 9
Homologene: 23210
Trim24
Name: tripartite motif-containing 24
Synonyms: D430004I05Rik, A130082H20Rik, Tif1a, TIF1alpha
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 21848
Homologene: 20830
Kpna3
Name: karyopherin (importin) alpha 3
Synonyms: IPOA4, importin alpha 4, importin alpha 4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 16648
VEGA: 14
HGNC: HGNC:6396
Homologene: 20520
Sin3a
Name: transcriptional regulator, SIN3A (yeast)
Synonyms: Sin3, mSin3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 20466
Homologene: 32124
Itgb2
Name: integrin beta 2
Synonyms: Mac-1 beta, Cd18, 2E6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16414
HGNC: HGNC:6155
Homologene: 20092
Rpf1
Name: ribosome production factor 1 homolog
Synonyms: 2310066N05Rik, Bxdc5, 2210420E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70285
Homologene: 68728
Rock1
Name: Rho-associated coiled-coil containing protein kinase 1
Synonyms: 1110055K06Rik, Rock-I
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 19877
VEGA: 18
Homologene: 55899
Thra
Name: thyroid hormone receptor alpha
Synonyms: T3R[a], Thra1, T3Ralpha, Nr1a1, TR alpha 1, TR alpha 2, c-erbAalpha, 6430529J03Rik, Erba, Thra2, Rvr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 21833
Homologene: 37747
Ptgfrn
Name: prostaglandin F2 receptor negative regulator
Synonyms: 4833445A08Rik, CD9P-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 19221
HGNC: HGNC:9601
Homologene: 7908
Arhgdib
Name: Rho, GDP dissociation inhibitor (GDI) beta
Synonyms: Ly-GDI, Gdid4, D4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 11857
HGNC: HGNC:679
Homologene: 20318
Sidt2
Name: SID1 transmembrane family, member 2
Synonyms: CGI-40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 214597
Homologene: 22943
Npat
Name: nuclear protein in the AT region
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 244879
HGNC: HGNC:7896
Homologene: 1888
Ankrd26
Name: ankyrin repeat domain 26
Synonyms: 5730521P14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232339
Homologene: 45968
Cmip
Name: c-Maf inducing protein
Synonyms: 5830471E12Rik, 4933407C03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74440
Homologene: 18869
Map4k3
Name: mitogen-activated protein kinase kinase kinase kinase 3
Synonyms: 9530052P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225028
VEGA: 17
HGNC: HGNC:6865
Homologene: 2683
Tpcn2
Name: two pore segment channel 2
Synonyms: D830047E22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233979
Homologene: 16375
Lcorl
Name: ligand dependent nuclear receptor corepressor-like
Synonyms: Mlr1, A830039H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 209707
Homologene: 82325
Eps8l2
Name: EPS8-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 98845
Homologene: 69358
Fgfr4
Name: fibroblast growth factor receptor 4
Synonyms: Fgfr-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 14186
HGNC: HGNC:3691
Homologene: 20461
Prlr
Name: prolactin receptor
Synonyms: Pr-1, Prlr-rs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19116
HGNC: HGNC:9446
Homologene: 733
Dnah5
Name: dynein, axonemal, heavy chain 5
Synonyms: b2b1154Clo, b2b1537Clo, Dnahc5, b2b3491Clo, b2b1565Clo, Mdnah5, b2b1134Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 110082
HGNC: HGNC:2950
Homologene: 1048
Gpn1
Name: GPN-loop GTPase 1
Synonyms: 2410004J02Rik, Xab1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 74254
Homologene: 5257
Tnr
Name: tenascin R
Synonyms: J1-tenascin, janusin, restrictin, TN-R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 21960
Homologene: 124416
Lama4
Name: laminin, alpha 4
Synonyms: laminin [a]4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 16775
HGNC: HGNC:6484
Homologene: 37604
Ccdc146
Name: coiled-coil domain containing 146
Synonyms: 4930528G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75172
Homologene: 67159
Kcnt1
Name: potassium channel, subfamily T, member 1
Synonyms: Slack, slo2, C030030G16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227632
Homologene: 11055
Col22a1
Name: collagen, type XXII, alpha 1
Synonyms: 2310067L16Rik, C80743
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 69700
Homologene: 43567
Usp4
Name: ubiquitin specific peptidase 4 (proto-oncogene)
Synonyms: Unp, F730026I20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 22258
Homologene: 20716
Eri2
Name: exoribonuclease 2
Synonyms: Exod1, 4933424N09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 71151
Homologene: 12383
Gramd1a
Name: GRAM domain containing 1A
Synonyms: D7Bwg0611e, 1300003M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 52857
Homologene: 10843
Sectm1b
Name: secreted and transmembrane 1B
Synonyms: 1810003C24Rik, K12, Sectm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 58210
Homologene: 86740
Vmn2r118
Name: vomeronasal 2, receptor 118
Synonyms: Vmn2r119, EG383258, EG668547
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 383258
Homologene: 129687
Mmp8
Name: matrix metallopeptidase 8
Synonyms: Collagenase-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17394
VEGA: 9
HGNC: HGNC:7175
Homologene: 22482
Slc16a14
Name: solute carrier family 16 (monocarboxylic acid transporters), member 14
Synonyms: 1110004H10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 71781
Homologene: 34318
Stc1
Name: stanniocalcin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 20855
VEGA: 14
Homologene: 2374
Hivep3
Name: human immunodeficiency virus type I enhancer binding protein 3
Synonyms: Krc, Schnurri-3, 2900056N03Rik, E030045D18Rik, Shn3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 16656
Homologene: 7803
Gpr176
Name: G protein-coupled receptor 176
Synonyms: LOC381413
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381413
Homologene: 5226
Cpeb1
Name: cytoplasmic polyadenylation element binding protein 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 12877
Homologene: 7278
Krt80
Name: keratin 80
Synonyms: Kb20, 2310041I20Rik, 1200016G03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 74127
VEGA: 15
Homologene: 66610
Sestd1
Name: SEC14 and spectrin domains 1
Synonyms: 1500031J16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228071
Homologene: 45505
Olfr1246
Name: olfactory receptor 1246
Synonyms: GA_x6K02T2Q125-51034790-51033846, MOR231-9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258788
Homologene: 74246
Tmem8
Name: transmembrane protein 8
Synonyms: Rxylt1, M83, Tmem8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 60455
Homologene: 10944
Zfp850
Name: zinc finger protein 850
Synonyms: C130069I09Rik, Gm4636
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100043772
Cybb
Name: cytochrome b-245, beta polypeptide
Synonyms: gp91phox, Nox2, gp91phox, Cgd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
NCBI: 13058
HGNC: HGNC:2578
Homologene: 68054
Crebzf
Name: CREB/ATF bZIP transcription factor
Synonyms: 1110034C16Rik, 6330417B10Rik, LAZip, LAZipII, Zf
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233490
Homologene: 10926
Tbx6
Name: T-box 6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 21389
Homologene: 3389
Vmn1r88
Name: vomeronasal 1 receptor, 88
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 100312474
Homologene: 74345
Wdr74
Name: WD repeat domain 74
Synonyms: 5730436H21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 107071
Homologene: 41226
Trdv2-2
Name: T cell receptor delta variable 2-2
Synonyms: Gm17015
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 320913
Polr3h
Name: polymerase (RNA) III (DNA directed) polypeptide H
Synonyms: 5031409G22Rik, RPC8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 78929
VEGA: 15
Homologene: 6337
Gm5108
Name: predicted gene 5108
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 330097
Igkv12-40
Name: immunoglobulin kappa chain variable 12-40
Synonyms: Gm5722
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 435904
D630036H23Rik
Name: RIKEN cDNA D630036H23 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 75,524,691 bp
  • T to C, chromosome 1 at 84,912,267 bp
  • T to C, chromosome 1 at 159,912,766 bp
  • T to A, chromosome 2 at 25,909,376 bp
  • T to A, chromosome 2 at 77,187,159 bp
  • T to A, chromosome 2 at 89,591,100 bp
  • T to A, chromosome 2 at 118,373,040 bp
  • A to T, chromosome 3 at 101,060,652 bp
  • A to T, chromosome 3 at 146,519,463 bp
  • T to A, chromosome 3 at 153,939,108 bp
  • T to A, chromosome 4 at 110,290,243 bp
  • A to G, chromosome 4 at 120,097,108 bp
  • G to A, chromosome 4 at 155,648,240 bp
  • T to A, chromosome 5 at 21,308,621 bp
  • T to C, chromosome 5 at 31,500,891 bp
  • G to T, chromosome 5 at 45,725,424 bp
  • T to G, chromosome 5 at 67,976,871 bp
  • T to A, chromosome 6 at 37,958,569 bp
  • A to G, chromosome 6 at 69,879,399 bp
  • T to A, chromosome 6 at 72,843,005 bp
  • T to A, chromosome 6 at 84,207,212 bp
  • A to G, chromosome 6 at 118,507,636 bp
  • A to T, chromosome 6 at 136,924,138 bp
  • A to T, chromosome 7 at 13,178,513 bp
  • C to A, chromosome 7 at 27,990,195 bp
  • A to G, chromosome 7 at 31,139,821 bp
  • T to C, chromosome 7 at 81,361,680 bp
  • C to T, chromosome 7 at 90,444,323 bp
  • C to A, chromosome 7 at 119,786,068 bp
  • G to A, chromosome 7 at 126,784,853 bp
  • A to T, chromosome 7 at 141,356,346 bp
  • T to A, chromosome 7 at 145,278,784 bp
  • C to A, chromosome 8 at 72,749,878 bp
  • A to T, chromosome 8 at 117,257,309 bp
  • T to A, chromosome 9 at 7,563,202 bp
  • T to C, chromosome 9 at 45,944,454 bp
  • A to T, chromosome 9 at 53,562,221 bp
  • A to T, chromosome 9 at 57,111,111 bp
  • T to G, chromosome 9 at 108,391,760 bp
  • T to C, chromosome 9 at 108,597,383 bp
  • A to G, chromosome 9 at 123,017,261 bp
  • A to G, chromosome 10 at 39,072,812 bp
  • C to A, chromosome 10 at 77,546,034 bp
  • A to T, chromosome 11 at 23,268,653 bp
  • A to T, chromosome 11 at 23,268,656 bp
  • T to G, chromosome 11 at 30,804,294 bp
  • T to A, chromosome 11 at 80,127,285 bp
  • G to A, chromosome 11 at 98,763,688 bp
  • T to C, chromosome 11 at 121,055,674 bp
  • C to A, chromosome 12 at 36,381,672 bp
  • T to A, chromosome 13 at 55,166,887 bp
  • T to C, chromosome 14 at 53,961,541 bp
  • C to T, chromosome 14 at 61,384,647 bp
  • A to G, chromosome 14 at 65,582,177 bp
  • T to C, chromosome 14 at 69,032,373 bp
  • C to T, chromosome 15 at 10,322,446 bp
  • A to T, chromosome 15 at 28,335,718 bp
  • G to T, chromosome 15 at 72,006,966 bp
  • G to T, chromosome 15 at 81,917,279 bp
  • A to G, chromosome 15 at 101,364,208 bp
  • T to C, chromosome 17 at 26,121,998 bp
  • A to G, chromosome 17 at 55,624,494 bp
  • A to G, chromosome 17 at 80,613,919 bp
  • T to C, chromosome 18 at 10,116,792 bp
  • T to C, chromosome 19 at 8,739,833 bp
  • C to G, chromosome X at 9,450,750 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5927 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044122-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.