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Strain Name:
C57BL/6J-MtgxR5934Btlr/Mmmh
Stock Number:
044128-MU
Citation ID:
RRID:MMRRC_044128-MU
Other Names:
R5934 (G1)
Major Collection:

Strain Information

Nos1
Name: nitric oxide synthase 1, neuronal
Synonyms: nNOS, bNOS, Nos-1, NO, 2310005C01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18125
HGNC: HGNC:7872
Homologene: 37327
Slc27a4
Name: solute carrier family 27 (fatty acid transporter), member 4
Synonyms: fatty acid transport protein 4, FATP4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26569
Homologene: 68437
Cep70
Name: centrosomal protein 70
Synonyms: 6720484E09Rik, C030018L16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68121
Homologene: 11387
Rai14
Name: retinoic acid induced 14
Synonyms: 1700020L11Rik, Ankycorbin, Norpeg, 1700008J19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75646
VEGA: 15
Homologene: 9199
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 2510002A14Rik, 9030227G01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72313
Homologene: 103956
Gpr88
Name: G-protein coupled receptor 88
Synonyms: Strg
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 64378
HGNC: HGNC:4539
Homologene: 11104
Rgs4
Name: regulator of G-protein signaling 4
Synonyms: ESTM50, ESTM48
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19736
Homologene: 4100
Pard3
Name: par-3 family cell polarity regulator
Synonyms: ASIP, D8Ertd580e, PAR-3, Par3, Pard3a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 93742
Homologene: 10489
Sf3b3
Name: splicing factor 3b, subunit 3
Synonyms: 5730409A01Rik, 1810061H24Rik, SAP130, RSE1, D8Ertd633e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 101943
Homologene: 6579
Kif20b
Name: kinesin family member 20B
Synonyms: N-6 kinesin, C330014J10Rik, Kif20b, Mphosph1, 33cex, magoo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240641
VEGA: 19
HGNC: HGNC:7212
Homologene: 9418
Usp19
Name: ubiquitin specific peptidase 19
Synonyms: 8430421I07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71472
Homologene: 41730
Dop1a
Name: DOP1 leucine zipper like protein A
Synonyms: B130005I07Rik, D9Ertd809e, Dopey1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320615
Homologene: 26645
Tsc22d1
Name: TSC22 domain family, member 1
Synonyms: TSC-22, Egr5, Tgfb1i4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 21807
Homologene: 7573
Prrc2a
Name: proline-rich coiled-coil 2A
Synonyms: G2, Bat-2, D17H6S51E, Wbp12, 3110039B05Rik, Bat2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 53761
Homologene: 10567
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Ift74
Name: intraflagellar transport 74
Synonyms: 1700029H06Rik, Cmg1, Ccdc2, b2b796Clo
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67694
Homologene: 11831
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, LOC381026, 9330188B09Rik, D630001M17Rik, 4921513O20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66725
Homologene: 18982
Gapdh
Name: glyceraldehyde-3-phosphate dehydrogenase
Synonyms: Gapd, Gapd
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14433
HGNC: HGNC:4141
Homologene: 107053
Zswim6
Name: zinc finger SWIM-type containing 6
Synonyms: 2900036G02Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67263
VEGA: 13
Homologene: 83517
Pigr
Name: polymeric immunoglobulin receptor
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18703
HGNC: HGNC:8968
Homologene: 1984
Ckb
Name: creatine kinase, brain
Synonyms: Ck-3, B-CK
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 12709
VEGA: 12
HGNC: HGNC:1991
Homologene: 37530
Hspg2
Name: perlecan (heparan sulfate proteoglycan 2)
Synonyms: per, Pcn, Plc, perlecan
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 15530
HGNC: HGNC:5273
Homologene: 68473
Rab22a
Name: RAB22A, member RAS oncogene family
Synonyms: E130120E14Rik, 3732413A17Rik, Rab22
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19334
HGNC: HGNC:9764
Homologene: 10782
Reck
Name: reversion-inducing-cysteine-rich protein with kazal motifs
Synonyms: St15
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 53614
Homologene: 9622
Ddhd2
Name: DDHD domain containing 2
Synonyms: SAMWD1, 2010305K11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72108
Homologene: 66646
Zfp574
Name: zinc finger protein 574
Synonyms: A630056B21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232976
Homologene: 11238
Abcb4
Name: ATP-binding cassette, sub-family B member 4
Synonyms: mdr-2, Mdr2, Pgy-2, Pgy2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18670
HGNC: HGNC:45
Homologene: 136368
Atp1a3
Name: ATPase, Na+/K+ transporting, alpha 3 polypeptide
Synonyms: Atpa-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232975
HGNC: HGNC:801
Homologene: 113729
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Or1j20
Name: olfactory receptor family 1 subfamily J member 20
Synonyms: GA_x6K02T2NLDC-33564136-33565083, MOR136-10, Olfr352
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258942
Homologene: 121523
Ptpdc1
Name: protein tyrosine phosphatase domain containing 1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218232
VEGA: 13
Homologene: 17576
Xirp2
Name: xin actin-binding repeat containing 2
Synonyms: A530024P18Rik, 2310008C07Rik, 2310003D02Rik, mXin beta, myomaxin, Cmya3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241431
Homologene: 19388
Cdh5
Name: cadherin 5
Synonyms: VE-cadherin, 7B4/cadherin-5, VEC, CD144, VE-Cad, VECD, VEcad
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12562
HGNC: HGNC:1764
Homologene: 1359
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245026
Homologene: 18260
Heg1
Name: heart development protein with EGF-like domains 1
Synonyms: LOC268884, 5530401I02Rik, 9530025L16Rik, 4632417D23Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 77446
Homologene: 35276
Tmem184c
Name: transmembrane protein 184C
Synonyms: 8430433H16Rik, Tmem34
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234463
Homologene: 32403
Cd96
Name: CD96 antigen
Synonyms: Tactile, 1700109I12Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 84544
Homologene: 68489
Or5w8
Name: olfactory receptor family 5 subfamily W member 8
Synonyms: GA_x6K02T2Q125-49358694-49359620, MOR177-9, Olfr1151
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258631
Homologene: 36999
Mucl2
Name: mucin-like 2
Synonyms: Spt-1, Spt1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20770
Homologene: 137219
Polr1e
Name: polymerase (RNA) I polypeptide E
Synonyms: 53kDa, D030019D19Rik, Paf53, Praf1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 64424
Homologene: 41486
Apcdd1
Name: adenomatosis polyposis coli down-regulated 1
Synonyms: EIG180, Drapc1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 494504
VEGA: 18
Homologene: 77420
Or56a5
Name: olfactory receptor family 56 subfamily A member 5
Synonyms: GA_x6K02T2PBJ9-7773007-7772066, MOR40-1, Olfr683
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259047
Homologene: 133645
Acot11
Name: acyl-CoA thioesterase 11
Synonyms: BFIT1, 2010309H15Rik, Them1, 1110020M10Rik, Thea
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 329910
Homologene: 11977
Sult1d1
Name: sulfotransferase family 1D, member 1
Synonyms: tyrosine-ester sulfotransferase, 5033411P13Rik, Sultn
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 53315
Homologene: 124464
Tchh
Name: trichohyalin
Synonyms: Thh, AHF
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99681
Homologene: 136273
Musk
Name: muscle, skeletal, receptor tyrosine kinase
Synonyms: MDK4, Nsk1, Nsk2, Nsk3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18198
HGNC: HGNC:7525
Homologene: 4084
Mpp4
Name: membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
Synonyms: DLG6
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227157
Homologene: 23296
Or52e15
Name: olfactory receptor family 52 subfamily E member 15
Synonyms: GA_x6K02T2PBJ9-7625746-7624808, MOR32-4, Olfr672
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258755
Homologene: 138317
Or8u8
Name: olfactory receptor family 8 subfamily U member 8
Synonyms: IE6, MOR185-6, GA_x6K02T2Q125-47650922-47649963, Olfr52
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18352
Homologene: 105200
Kcnh3
Name: potassium voltage-gated channel, subfamily H (eag-related), member 3
Synonyms: ether a go-go like, Elk2, Melk2, C030044P22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16512
VEGA: 15
HGNC: HGNC:6252
Homologene: 32150
Gmeb2
Name: glucocorticoid modulatory element binding protein 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 229004
HGNC: HGNC:4371
Homologene: 8228
Or4d2
Name: olfactory receptor family 4 subfamily D member 2
Synonyms: GA_x6K02T2PAEV-9540823-9539888, MOR240-1, Olfr463
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258408
HGNC: HGNC:8294
Homologene: 64870
Msl2
Name: MSL complex subunit 2
Synonyms: E130103E02Rik, Rnf184, Msl2l1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77853
Homologene: 10021
Or2at1
Name: olfactory receptor family 2 subfamily AT member 1
Synonyms: GA_x6K02T2PBJ9-2443810-2444775, MOR101-2, Olfr521
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258353
Homologene: 128108
Macir
Name: macrophage immunometabolism regulator
Synonyms: D1Ertd622e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 52392
Homologene: 13239
Aldh2
Name: aldehyde dehydrogenase 2, mitochondrial
Synonyms: Ahd5, Ahd-5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11669
HGNC: HGNC:404
Homologene: 55480
Calhm5
Name: calcium homeostasis modulator family member 5
Synonyms: Fam26e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103511
VEGA: 10
Homologene: 17807
Hdhd3
Name: haloacid dehalogenase-like hydrolase domain containing 3
Synonyms: 2810435D12Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72748
Homologene: 11497
Ugt1a7c
Name: UDP glucuronosyltransferase 1 family, polypeptide A7C
Synonyms: A10'
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 394432
Homologene: 136043
Cysltr2
Name: cysteinyl leukotriene receptor 2
Synonyms: CYSLT2R, Cyslt2, CysLT2, 2300001H05Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70086
VEGA: 14
Homologene: 10688
Or10v1
Name: olfactory receptor family 10 subfamily V member 1
Synonyms: GA_x6K02T2RE5P-2247227-2248156, MOR266-4, Olfr1420
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258405
Homologene: 17234
Psma5-ps
Name: proteasome subunit alpha 5, pseudogene
Synonyms: Gm8394
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 666974
VEGA: 10
Or10d4b
Name: olfactory receptor family 10 subfamily D member 4B
Synonyms: GA_x6K02T2PVTD-33320043-33320987, MOR224-12, Olfr960
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258276
VEGA: 9
Homologene: 17168
Lace1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 59,121,376 bp
  • G to T, chromosome 1 at 88,095,879 bp
  • A to T, chromosome 1 at 97,645,930 bp
  • A to T, chromosome 1 at 130,844,527 bp
  • T to C, chromosome 1 at 169,745,238 bp
  • G to T, chromosome 2 at 29,811,660 bp
  • T to A, chromosome 2 at 36,870,268 bp
  • T to A, chromosome 2 at 67,524,804 bp
  • G to A, chromosome 2 at 82,986,748 bp
  • T to A, chromosome 2 at 86,182,102 bp
  • T to C, chromosome 2 at 87,857,241 bp
  • A to G, chromosome 2 at 173,661,504 bp
  • T to C, chromosome 2 at 181,255,574 bp
  • A to T, chromosome 3 at 93,444,112 bp
  • C to T, chromosome 3 at 116,252,309 bp
  • G to A, chromosome 4 at 43,930,979 bp
  • T to C, chromosome 4 at 45,029,369 bp
  • T to A, chromosome 4 at 58,373,613 bp
  • C to A, chromosome 4 at 62,499,370 bp
  • A to T, chromosome 4 at 94,632,734 bp
  • C to T, chromosome 4 at 106,760,130 bp
  • A to G, chromosome 4 at 137,518,772 bp
  • T to C, chromosome 5 at 8,930,806 bp
  • T to C, chromosome 5 at 73,090,717 bp
  • CCATG to CCATGGCATG, chromosome 5 at 87,559,770 bp
  • A to G, chromosome 5 at 117,936,445 bp
  • T to C, chromosome 5 at 121,579,615 bp
  • A to G, chromosome 6 at 125,162,701 bp
  • T to C, chromosome 7 at 24,978,874 bp
  • G to A, chromosome 7 at 25,080,332 bp
  • A to T, chromosome 7 at 99,767,389 bp
  • C to A, chromosome 7 at 104,996,178 bp
  • G to A, chromosome 7 at 105,143,660 bp
  • A to G, chromosome 8 at 25,753,113 bp
  • A to T, chromosome 8 at 77,604,723 bp
  • T to A, chromosome 8 at 104,138,268 bp
  • A to G, chromosome 8 at 110,823,470 bp
  • T to G, chromosome 8 at 127,389,338 bp
  • C to T, chromosome 9 at 39,623,183 bp
  • T to A, chromosome 9 at 86,542,442 bp
  • T to C, chromosome 9 at 99,254,265 bp
  • T to C, chromosome 9 at 101,101,818 bp
  • C to T, chromosome 9 at 105,767,075 bp
  • C to T, chromosome 9 at 108,492,567 bp
  • A to G, chromosome 10 at 34,092,202 bp
  • G to A, chromosome 10 at 42,318,686 bp
  • T to C, chromosome 10 at 85,314,281 bp
  • C to T, chromosome 11 at 82,956,592 bp
  • T to A, chromosome 11 at 83,121,944 bp
  • T to C, chromosome 11 at 87,893,223 bp
  • G to T, chromosome 11 at 118,041,102 bp
  • A to T, chromosome 12 at 111,670,229 bp
  • A to T, chromosome 13 at 11,584,154 bp
  • T to C, chromosome 13 at 48,586,369 bp
  • A to G, chromosome 13 at 107,744,107 bp
  • T to C, chromosome 14 at 73,029,491 bp
  • T to G, chromosome 14 at 76,418,826 bp
  • A to G, chromosome 14 at 96,123,215 bp
  • T to A, chromosome 15 at 10,575,159 bp
  • T to C, chromosome 15 at 91,734,046 bp
  • G to A, chromosome 15 at 99,226,533 bp
  • A to T, chromosome 15 at 103,897,566 bp
  • C to T, chromosome 16 at 33,726,919 bp
  • G to T, chromosome 16 at 46,117,903 bp
  • A to T, chromosome 17 at 35,150,084 bp
  • C to T, chromosome 18 at 62,951,869 bp
  • A to G, chromosome 19 at 11,896,929 bp
  • G to T, chromosome 19 at 34,941,321 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5934 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044128-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.